Q3U2U7
Gene name |
Mettl17 |
Protein name |
Methyltransferase-like protein 17, mitochondrial |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:52535 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3U2U7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3U2U7-F1 | Predicted | AlphaFoldDB |
27 variants for Q3U2U7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3404992190 | 17 | C>F | No | EVA | |
| rs3389279406 | 55 | G>D | No | EVA | |
| rs3389321806 | 62 | V>I | No | EVA | |
| rs3404334068 | 77 | F>Y | No | EVA | |
| rs3404650344 | 84 | V>I | No | EVA | |
| rs3389279421 | 94 | Y>H | No | EVA | |
| rs3389326817 | 106 | E>G | No | EVA | |
| rs3389336495 | 118 | F>I | No | EVA | |
| rs3405400023 | 159 | Y>F | No | EVA | |
| rs3405081757 | 196 | G>D | No | EVA | |
| rs3405145231 | 206 | R>S | No | EVA | |
| rs3389324604 | 217 | C>S | No | EVA | |
| rs3389321548 | 232 | L>M | No | EVA | |
| rs3389298226 | 238 | S>L | No | EVA | |
| rs3389340970 | 261 | D>V | No | EVA | |
| rs3389249413 | 265 | S>* | No | EVA | |
| rs3389340888 | 291 | H>N | No | EVA | |
| rs3389298225 | 302 | A>V | No | EVA | |
| rs3405399974 | 314 | V>A | No | EVA | |
| rs3389279431 | 336 | H>Q | No | EVA | |
| rs3389324642 | 337 | E>* | No | EVA | |
| rs3389336526 | 339 | P>H | No | EVA | |
| rs3389249338 | 351 | C>Y | No | EVA | |
| rs3389324584 | 353 | F>I | No | EVA | |
| rs3404992163 | 426 | R>M | No | EVA | |
| rs3389298190 | 446 | P>T | No | EVA | |
| rs3405266428 | 458 | P>H | No | EVA |
No associated diseases with Q3U2U7
No regional properties for Q3U2U7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q3U2U7 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| methyltransferase activity | Catalysis of the transfer of a methyl group to an acceptor molecule. |
| mitochondrial ribosome binding | Binding to a mitochondrial ribosome. |
| S-adenosyl-L-methionine binding | Binding to S-adenosyl-L-methionine. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| methylation | The process in which a methyl group is covalently attached to a molecule. |
| ribosomal small subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATARTPRFL | LLFCRSCRSL | RGPQSRAYAA | LVPGVSQVDN | GSDFLGKKPH | RKHPGILHLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HVQLPQALAD | AAQLMLFERP | MRSVEKQVQA | LTNYLWSRHL | PVEPEELQRR | AAYLEKKFLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KQDSAPTEEK | LREAVLHALR | KTTYHWQELS | YSEELSLIYM | AARLDGGFAA | VFRAFHEIQA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RIPEFRPQTL | MDFGSGTGSV | AWAAHRTWGQ | SLREYVCVDS | SAAMLGLAEK | LLKGGSESGK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PCIPGVFFRQ | FLPVSPKVQF | DVVVSAYALS | ELPSRADRIE | VIQNLWRKTS | HFLVLVENGT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KAGHRLLMDA | RNLVLGEKEK | SPLDLRPSFV | FAPCPHELPC | PQLNASKSLA | CSFSQAYHPI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PFNWNKKPKE | EIFSMVILAR | GSPKEANRWP | RITQPVLKRP | RHVHCHLCCP | DGHMQHAVVT |
| 430 | 440 | 450 | 460 | ||
| ARRHGRDLYR | CARVSSWGDL | LPVIAPSEFP | PSSPDEEPPE | N |