Q3SWZ4
Gene name |
EXOSC9 |
Protein name |
Exosome complex component RRP45 |
Names |
Exosome component 9 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:508005 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3SWZ4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3SWZ4-F1 | Predicted | AlphaFoldDB |
No variants for Q3SWZ4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3SWZ4 | |||||
No associated diseases with Q3SWZ4
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| exosome (RNase complex) | A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. |
| nuclear chromosome | A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKETPLSNCE | RRFLLRAIEE | KKRLDGRQTY | DYRNIKISFG | TDYGCCIVEL | GKTRVLGQVS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CELVSPKLNR | ATEGILFFNL | ELSQMAAPAF | EPGRQSDLLV | KLNRLLERCL | RNSKCIDTES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LCVVAGEKVW | QIRVDLHLLN | HDGNIIDAAS | IAAIVALCHF | RRPDVSVQGD | EVTLYTLEER |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DPVPLSIHHM | PICVSFAFFQ | QGTYLLVDPS | EREERVMDGL | LVIAMNKHRE | ICTIQSSGGI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MLLKDQVLRC | SKIAGVKVVE | ITELIQKALE | NDQKVRKEGG | KFGFVESMAN | QRITAFKMEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| APIDTSDVEE | KAEEIISEAE | PPSEVVSKPV | LWTPGTAQIG | EGIENSWGHL | EDSEKEDEDE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GGSDEAIILD | GMKMDTGVEV | SNIGSQDAPI | VLSDSEEEEM | IILEPDKNPK | KIRTQTISAT |
| 430 | |||||
| QVKAPSKKPV | KKRKKKRAAN |