Q3EAQ9

PR
Gene name
At3g43550 (T18D12.120)
Protein name
GDSL esterase/lipase At3g43550
Names
Extracellular lipase At3g43550
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G43550
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

205-281 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3EAQ9

Entry ID Method Resolution Chain Position Source
AF-Q3EAQ9-F1 Predicted AlphaFoldDB

81 variants for Q3EAQ9

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00392153 8 L>F No 1000Genomes
ENSVATH06173356 9 A>P No 1000Genomes
ENSVATH06173357 13 I>N No 1000Genomes
ENSVATH09418459 17 T>A No 1000Genomes
ENSVATH09418460 18 Y>N No 1000Genomes
ENSVATH02385036 23 G>R No 1000Genomes
ENSVATH12266812 26 V>L No 1000Genomes
tmp_3_15448780_C_A 49 T>N No 1000Genomes
tmp_3_15448782_C_T 50 L>F No 1000Genomes
ENSVATH02385039 58 Y>* No 1000Genomes
ENSVATH12266821 68 T>S No 1000Genomes
ENSVATH09418461 75 R>K No 1000Genomes
tmp_3_15448860_G_A 76 V>I No 1000Genomes
ENSVATH12266824 77 P>S No 1000Genomes
ENSVATH14306786 79 D>N No 1000Genomes
ENSVATH14306786 79 D>Y No 1000Genomes
tmp_3_15448878_G_A 82 A>T No 1000Genomes
ENSVATH02385051 88 V>A No 1000Genomes
ENSVATH02385050 88 V>I No 1000Genomes
ENSVATH02385053 96 N>I No 1000Genomes
tmp_3_15449014_C_T 97 P>L No 1000Genomes
tmp_3_15449026_C_T 101 P>L No 1000Genomes
tmp_3_15449025_C_T 101 P>S No 1000Genomes
ENSVATH02385054 102 H>D No 1000Genomes
ENSVATH02385054 102 H>N No 1000Genomes
ENSVATH02385055 102 H>Q No 1000Genomes
ENSVATH06173368 107 G>R No 1000Genomes
ENSVATH02385056 112 S>Y No 1000Genomes
tmp_3_15449062_G_A 113 G>E No 1000Genomes
ENSVATH02385057 114 G>* No 1000Genomes
ENSVATH14306790 116 G>S No 1000Genomes
ENSVATH12266875 118 D>Y No 1000Genomes
ENSVATH06173369 119 P>S No 1000Genomes
tmp_3_15449086_C_T 121 T>I No 1000Genomes
ENSVATH02385058 125 M>I No 1000Genomes
ENSVATH12266884 139 E>K No 1000Genomes
ENSVATH14306792 167 S>T No 1000Genomes
ENSVATH12266924 179 A>V No 1000Genomes
ENSVATH06173375 184 R>H No 1000Genomes
ENSVATH12266950 194 S>C No 1000Genomes
ENSVATH12266950 194 S>F No 1000Genomes
ENSVATH08113395 195 A>V No 1000Genomes
ENSVATH02385079 197 H>D No 1000Genomes
ENSVATH02385079 197 H>Y No 1000Genomes
ENSVATH12266952 198 F>L No 1000Genomes
ENSVATH08113402 203 H>Y No 1000Genomes
tmp_3_15449511_A_G 204 K>R No 1000Genomes
ENSVATH06173383 205 L>F No 1000Genomes
ENSVATH06173383 205 L>V No 1000Genomes
ENSVATH06173384 207 A>T No 1000Genomes
ENSVATH08113403 208 R>Q No 1000Genomes
tmp_3_15449529_T_A 210 I>N No 1000Genomes
ENSVATH06173386 211 G>R No 1000Genomes
ENSVATH12266988 212 V>M No 1000Genomes
ENSVATH06173388 214 S>C No 1000Genomes
ENSVATH06173391 217 P>L No 1000Genomes
ENSVATH06173390 217 P>S No 1000Genomes
ENSVATH06173392 218 V>F No 1000Genomes
ENSVATH06173392 218 V>I No 1000Genomes
tmp_3_15449564_C_T 222 P>S No 1000Genomes
ENSVATH14306793 227 V>G No 1000Genomes
ENSVATH12266991 234 R>K No 1000Genomes
ENSVATH08113404 244 A>S No 1000Genomes
tmp_3_15449631_C_T 244 A>V No 1000Genomes
ENSVATH02385088 249 A>E No 1000Genomes
tmp_3_15449649_G_A 250 R>K No 1000Genomes
ENSVATH08113405 252 S>Y No 1000Genomes
tmp_3_15449666_G_A 256 D>N No 1000Genomes
ENSVATH06173394 261 E>D No 1000Genomes
tmp_3_15449688_A_G 263 D>G No 1000Genomes
ENSVATH06173395 267 I>V No 1000Genomes
tmp_3_15449703_A_T 268 Y>F No 1000Genomes
tmp_3_15449705_A_T 269 I>F No 1000Genomes
tmp_3_15449723_C_G,T 275 L>F No 1000Genomes
tmp_3_15449723_C_G,T 275 L>V No 1000Genomes
ENSVATH08113406 281 H>Y No 1000Genomes
tmp_3_15449744_C_T 282 P>S No 1000Genomes
tmp_3_15449752_A_C 284 K>N No 1000Genomes
tmp_3_15449751_A_G 284 K>R No 1000Genomes
ENSVATH08113408 287 R>M No 1000Genomes
ENSVATH06173402 288 F>L No 1000Genomes

No associated diseases with Q3EAQ9

1 regional properties for Q3EAQ9

Type Name Position InterPro Accession
domain Armadillo repeat-containing domain 307 - 527 IPR006911

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
lipase activity Catalysis of the hydrolysis of a lipid or phospholipid.

1 GO annotations of biological process

Name Definition
lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0DI15 At1g59406 GDSL esterase/lipase At1g59406 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECM4 At1g58725 GDSL esterase/lipase At1g58725 Arabidopsis thaliana (Mouse-ear cress) PR
F4IBF0 At1g59030 GDSL esterase/lipase At1g59030 Arabidopsis thaliana (Mouse-ear cress) PR
P40602 APG Anther-specific proline-rich protein APG Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKLQIIWLAL VLIAVETYAV KQGKNVTIPA LIVFGDSIMD TGNNNNLPTL LKCNFPPYGK
70 80 90 100 110 120
DYPGGFATGR FSDGRVPSDL IAEKLGLVKT LPAYMNPYLK PHDLLKGVTF ASGGTGYDPL
130 140 150 160 170 180
TAKIMSVISV WDQLIYFKEY ISKIKRHFGE EKAKDILEHS FFLVVSSSND LAHTYLAQAH
190 200 210 220 230 240
RYDRTSYANF LADSAVHFVR ELHKLGARKI GVFSAVPVGC VPLQRTVFGG FFTRGCNQPL
250 260 270 280
NNMAKQFNAR LSPALDSLDK ELDGVIIYIN VYDTLFDMIQ HPKKYGRF