Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P40602

Entry ID Method Resolution Chain Position Source
AF-P40602-F1 Predicted AlphaFoldDB

55 variants for P40602

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01074291 3 R>Q No 1000Genomes
tmp_1_6977960_G_C 8 D>H No 1000Genomes
ENSVATH01074293 18 S>N No 1000Genomes
tmp_1_6977992_T_A 18 S>R No 1000Genomes
ENSVATH13930074 27 I>F No 1000Genomes
ENSVATH01074294 27 I>N No 1000Genomes
ENSVATH04606569 31 T>K No 1000Genomes
tmp_1_6978060_G_T 41 R>L No 1000Genomes
tmp_1_6978119_C_G 61 P>A No 1000Genomes
ENSVATH00033205 62 T>K No 1000Genomes
tmp_1_6978144_C_G 69 P>R No 1000Genomes
ENSVATH04606570 71 A>T No 1000Genomes
ENSVATH00033206 74 G>D No 1000Genomes
tmp_1_6978158_G_A 74 G>S No 1000Genomes
ENSVATH00033207 77 S>P No 1000Genomes
ENSVATH11591069 78 K>N No 1000Genomes
tmp_1_6978173_C_T 79 P>S No 1000Genomes
tmp_1_6978198_C_A 87 P>Q No 1000Genomes
ENSVATH04606572 100 P>S No 1000Genomes
ENSVATH01074295 111 P>T No 1000Genomes
ENSVATH13930116 119 P>A No 1000Genomes
tmp_1_6978297_T_C 120 V>A No 1000Genomes
ENSVATH04606573 121 P>A No 1000Genomes
tmp_1_6978305_C_G 123 P>A No 1000Genomes
ENSVATH13930117 127 P>S No 1000Genomes
tmp_1_6978348_C_T 137 A>V No 1000Genomes
ENSVATH04606575 138 P>S No 1000Genomes
ENSVATH01074296 141 E>A No 1000Genomes
ENSVATH01074297 144 P>A No 1000Genomes
tmp_1_6978387_C_T 150 P>L No 1000Genomes
ENSVATH11591071 153 V>F No 1000Genomes
tmp_1_6978418_G_C 160 K>N No 1000Genomes
tmp_1_6978419_C_G 161 P>A No 1000Genomes
ENSVATH04606576 167 K>Q No 1000Genomes
tmp_1_6978453_A_T 172 H>L No 1000Genomes
tmp_1_6978456_G_A 173 G>D No 1000Genomes
tmp_1_6978474_C_T 179 A>V No 1000Genomes
ENSVATH04606577 184 P>T No 1000Genomes
ENSVATH13930118 187 S>Y No 1000Genomes
tmp_1_6978509_G_C 191 A>P No 1000Genomes
ENSVATH01074298 221 L>R No 1000Genomes
tmp_1_6978876_A_T 258 Y>F No 1000Genomes
tmp_1_6979108_G_A 306 D>N No 1000Genomes
ENSVATH01074308 317 K>R No 1000Genomes
ENSVATH13930122 323 R>K No 1000Genomes
tmp_1_6979208_A_T 339 Q>L No 1000Genomes
tmp_1_6979247_G_A 352 S>N No 1000Genomes
tmp_1_6979481_G_C 391 G>R No 1000Genomes
tmp_1_6979488_G_A 393 G>E No 1000Genomes
tmp_1_6979502_G_T 398 G>* No 1000Genomes
ENSVATH01074316 418 I>V No 1000Genomes
ENSVATH13930127 441 L>V No 1000Genomes
ENSVATH00033212 453 M>L No 1000Genomes
tmp_1_6979893_C_T 499 P>S No 1000Genomes
ENSVATH04606587 525 I>L No 1000Genomes

No associated diseases with P40602

1 regional properties for P40602

Type Name Position InterPro Accession
active_site Lipase, GDSL, active site 205 - 216 IPR008265

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
lipase activity Catalysis of the hydrolysis of a lipid or phospholipid.

1 GO annotations of biological process

Name Definition
lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0DI15 At1g59406 GDSL esterase/lipase At1g59406 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECM4 At1g58725 GDSL esterase/lipase At1g58725 Arabidopsis thaliana (Mouse-ear cress) PR
F4IBF0 At1g59030 GDSL esterase/lipase At1g59030 Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAQ9 At3g43550 GDSL esterase/lipase At3g43550 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKRSSLVDSC SYSRIFRSIF CLLSFCIFFL TTTNAQVMHR RLWPWPLWPR PYPQPWPMNP
70 80 90 100 110 120
PTPDPSPKPV APPGPSSKPV APPGPSPCPS PPPKPQPKPP PAPSPSPCPS PPPKPQPKPV
130 140 150 160 170 180
PPPACPPTPP KPQPKPAPPP EPKPAPPPAP KPVPCPSPPK PPAPTPKPVP PHGPPPKPAP
190 200 210 220 230 240
APTPAPSPKP APSPPKPENK TIPAVFFFGD SVFDTGNNNN LETKIKSNYR PYGMDFKFRV
250 260 270 280 290 300
ATGRFSNGMV ASDYLAKYMG VKEIVPAYLD PKIQPNDLLT GVSFASGGAG YNPTTSEAAN
310 320 330 340 350 360
AIPMLDQLTY FQDYIEKVNR LVRQEKSQYK LAGLEKTNQL ISKGVAIVVG GSNDLIITYF
370 380 390 400 410 420
GSGAQRLKND IDSYTTIIAD SAASFVLQLY GYGARRIGVI GTPPLGCVPS QRLKKKKICN
430 440 450 460 470 480
EELNYASQLF NSKLLLILGQ LSKTLPNSTF VYMDIYTIIS QMLETPAAYG FEETKKPCCK
490 500 510 520 530
TGLLSAGALC KKSTSKICPN TSSYLFWDGV HPTQRAYKTI NKVLIKEYLH VLSK