Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q38822

Entry ID Method Resolution Chain Position Source
AF-Q38822-F1 Predicted AlphaFoldDB

12 variants for Q38822

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH04517007 2 D>Y No 1000Genomes
ENSVATH10556496 20 D>G No 1000Genomes
tmp_1_1129257_A_C 21 N>K No 1000Genomes
ENSVATH00005146 45 E>A No 1000Genomes
ENSVATH01011233 47 E>Q No 1000Genomes
ENSVATH04517006 58 S>A No 1000Genomes
tmp_1_1129147_G_A 58 S>F No 1000Genomes
ENSVATH10556495 76 K>Q No 1000Genomes
tmp_1_1128840_T_C 133 E>G No 1000Genomes
ENSVATH00005143 139 G>V No 1000Genomes
ENSVATH04517003 168 I>M No 1000Genomes
ENSVATH00005142 178 K>E No 1000Genomes

No associated diseases with Q38822

2 regional properties for Q38822

Type Name Position InterPro Accession
domain PB1 domain 92 - 179 IPR000270
domain AUX/IAA domain 44 - 186 IPR033389

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
identical protein binding Binding to an identical protein or proteins.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

2 GO annotations of biological process

Name Definition
auxin-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
response to auxin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q7Y1H8 IAA14 Auxin-responsive protein IAA14 Oryza sativa subsp japonica (Rice) PR
P33077 IAA4 Auxin-responsive protein IAA4 Arabidopsis thaliana (Mouse-ear cress) PR
P49677 IAA1 Auxin-responsive protein IAA1 Arabidopsis thaliana (Mouse-ear cress) PR
P49678 IAA2 Auxin-responsive protein IAA2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZSY8 IAA27 Auxin-responsive protein IAA27 Arabidopsis thaliana (Mouse-ear cress) PR
Q38832 IAA14 Auxin-responsive protein IAA14 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDEFVNLKET ELRLGLPGTD NVCEAKERVS CCNNNNKRVL STDTEKEIES SSRKTETSPP
70 80 90 100 110 120
RKAQIVGWPP VRSYRKNNIQ SKKNESEHEG QGIYVKVSMD GAPYLRKIDL SCYKGYSELL
130 140 150 160 170 180
KALEVMFKFS VGEYFERDGY KGSDFVPTYE DKDGDWMLIG DVPWEMFICT CKRLRIMKGS
EAKGLGCGV