P49677
Gene name |
IAA1 (At4g14560, dl3320w, FCAALL.409) |
Protein name |
Auxin-responsive protein IAA1 |
Names |
Indoleacetic acid-induced protein 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G14560 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P49677
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5C7F | X-ray | 270 A | E/F/G/H | 10-20 | PDB |
| AF-P49677-F1 | Predicted | AlphaFoldDB |
21 variants for P49677
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14191193 | 2 | E>K | No | 1000Genomes | |
| ENSVATH11730155 | 6 | G>R | No | 1000Genomes | |
| tmp_4_8361219_A_C | 13 | E>A | No | 1000Genomes | |
| tmp_4_8361250_A_T | 23 | E>D | No | 1000Genomes | |
| ENSVATH00504084 | 29 | L>V | No | 1000Genomes | |
| tmp_4_8361270_C_T | 30 | S>F | No | 1000Genomes | |
| tmp_4_8361269_T_C | 30 | S>P | No | 1000Genomes | |
| tmp_4_8361289_C_G | 36 | N>K | No | 1000Genomes | |
| tmp_4_8361304_C_G | 41 | N>K | No | 1000Genomes | |
| ENSVATH11730156 | 44 | T>K | No | 1000Genomes | |
| ENSVATH06663712 | 46 | E>D | No | 1000Genomes | |
| ENSVATH11730157 | 52 | A>T | No | 1000Genomes | |
| tmp_4_8361475_A_G | 68 | N>D | No | 1000Genomes | |
| tmp_4_8361481_A_T | 70 | N>Y | No | 1000Genomes | |
| tmp_4_8361563_A_G | 97 | N>S | No | 1000Genomes | |
| tmp_4_8361606_C_G | 111 | F>L | No | 1000Genomes | |
| ENSVATH02832288 | 115 | E>G | No | 1000Genomes | |
| ENSVATH00504085 | 118 | E>K | No | 1000Genomes | |
| ENSVATH00504086 | 123 | K>Q | No | 1000Genomes | |
| tmp_4_8361659_C_T | 129 | P>L | No | 1000Genomes | |
| tmp_4_8361715_A_T | 148 | M>L | No | 1000Genomes |
No associated diseases with P49677
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| identical protein binding | Binding to an identical protein or proteins. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| auxin-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. |
| response to auxin | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q7Y1H8 | IAA14 | Auxin-responsive protein IAA14 | Oryza sativa subsp japonica (Rice) | PR |
| P33077 | IAA4 | Auxin-responsive protein IAA4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P49678 | IAA2 | Auxin-responsive protein IAA2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q38822 | IAA3 | Auxin-responsive protein IAA3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZSY8 | IAA27 | Auxin-responsive protein IAA27 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q38832 | IAA14 | Auxin-responsive protein IAA14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEVTNGLNLK | DTELRLGLPG | AQEEQQLELS | CVRSNNKRKN | NDSTEESAPP | PAKTQIVGWP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PVRSNRKNNN | NKNVSYVKVS | MDGAPYLRKI | DLKMYKNYPE | LLKALENMFK | FTVGEYSERE |
| 130 | 140 | 150 | 160 | ||
| GYKGSGFVPT | YEDKDGDWML | VGDVPWDMFS | SSCQKLRIMK | GSEAPTAL |