Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q32L49

Entry ID Method Resolution Chain Position Source
AF-Q32L49-F1 Predicted AlphaFoldDB

No variants for Q32L49

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q32L49

No associated diseases with Q32L49

1 regional properties for Q32L49

Type Name Position InterPro Accession
domain Golgi associated RAB2 interactor protein-like, Rab2B-binding domain 107 - 164 IPR022168

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
positive regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A1L3C1 Garin5a Golgi-associated RAB2 interactor protein 5A Mus musculus (Mouse) PR
10 20 30 40 50 60
MKRGHEPKPA FGGAGEAGPG VMAERPLVPA CPTGRPGRLQ RHLLSGEFDQ LRDFRIFESN
70 80 90 100 110 120
FVQVTRLGEV ANKVTMGVAA SSPALELPDL LLLAGPAKEN GHLQLFGLFP LQFVQLFVHD
130 140 150 160 170 180
ESRWQLKVKF RTGRAFYLQL RAPPESRDRE FGQWVRLLYR LRFHSAQGAV PFTQDYSALE
190 200 210
DDEDDDEDED RDLPAGELQA MEARLDPQMS ELWGL