Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for Q2TBR2

Entry ID Method Resolution Chain Position Source
2FTC EM - L 8-124 PDB
AF-Q2TBR2-F1 Predicted AlphaFoldDB

No variants for Q2TBR2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2TBR2

No associated diseases with Q2TBR2

No regional properties for Q2TBR2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q2TBR2

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
mitochondrial ribosome A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9BYC9 MRPL20 39S ribosomal protein L20, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MVFLSAPLWL RNRITDRYWR VQEVLKHARH FRGRKNRCYR LAVRAVTRAF VRCTRARSLK
70 80 90 100 110 120
KRHLRTLWIN RITAASQEHG LKYPAFILNL IKCQVELNRK VLADLAIYEP KTFKSLAALS
130 140
KRRREEGFVA ALGDGKEPEG IFSRVAQHH