Q2KIS1
Gene name |
RENBP |
Protein name |
N-acylglucosamine 2-epimerase |
Names |
AGE, GlcNAc 2-epimerase, N-acetyl-D-glucosamine 2-epimerase, Renin-binding protein, RnBP |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:516214 |
EC number |
5.1.3.8: Acting on carbohydrates and derivatives |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2KIS1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2KIS1-F1 | Predicted | AlphaFoldDB |
No variants for Q2KIS1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2KIS1 | |||||
No associated diseases with Q2KIS1
1 regional properties for Q2KIS1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Histone H2A/H2B/H3 | 1 - 132 | IPR007125 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.1.3.8 | Acting on carbohydrates and derivatives |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| N-acylglucosamine 2-epimerase activity | Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine. |
| peptidase inhibitor activity | Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| N-acetylglucosamine metabolic process | The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. |
| N-acetylmannosamine metabolic process | The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. |
| N-acetylneuraminate catabolic process | The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P82343 | Renbp | N-acylglucosamine 2-epimerase | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKEQETLRA | WKDRVARELD | RVVAFWLDHS | HDQEQGGFFT | CLGRDGQVYD | DLKYVWLQGR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVWMYCRLYR | QFERFRRPEL | LNAAKAGGEF | LLRYAQVAPP | AKKCAFVLTR | DGRPVKVQRT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IFSECFYTMA | MNELWRVTGD | ARYQNEAMEM | MDQIVSWVRE | DPSGLGRPQL | PGAPASESMA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VPMMLLNLVE | QLGEADEELA | GISAELGDWC | AQRILQHVQR | GGQAVLENVS | EDGEELSGCL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GRHQNPGHAL | EAGWFLLRYA | IQRGDAKLRA | HVIDKFLLLP | FHSGWDPEHG | GLFYFQDADG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LCPTQLEWAM | KLWWPHSEAM | IAFLMGYSET | GDPALLRIFY | QVAEYTFHRF | RDPEYGEWFG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLNRDGKVAL | TIKGGPFKGC | FHVPRCLAMC | EEMLNNLLSR | LAPASALSTR | SPPAGPTRPG |
| AE |