Q2KHY2
Gene name |
VAMP5 |
Protein name |
Vesicle-associated membrane protein 5 |
Names |
VAMP-5 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:540406 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2KHY2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2KHY2-F1 | Predicted | AlphaFoldDB |
37 variants for Q2KHY2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs442352273 | 13 | A>G | No | EVA | |
| rs441313827 | 14 | D>E | No | EVA | |
| rs461460115 | 14 | D>G | No | EVA | |
| rs472665567 | 15 | E>G | No | EVA | |
| rs472665567 | 15 | E>V | No | EVA | |
| rs452711110 | 16 | V>G | No | EVA | |
| rs438973143 | 17 | T>A | No | EVA | |
| rs476984556 | 17 | T>R | No | EVA | |
| rs456729166 | 19 | I>N | No | EVA | |
| rs467970621 | 25 | D>E | No | EVA | |
| rs436766898 | 25 | D>N | No | EVA | |
| rs434473150 | 27 | V>G | No | EVA | |
| rs465817980 | 30 | R>P | No | EVA | |
| rs477199665 | 31 | D>E | No | EVA | |
| rs456370831 | 49 | S>* | No | EVA | |
| rs456370831 | 49 | S>L | No | EVA | |
| rs436173055 | 53 | K>Q | No | EVA | |
| rs447541054 | 63 | R>G | No | EVA | |
| rs433984762 | 64 | W>C | No | EVA | |
| rs465292561 | 65 | E>G | No | EVA | |
| rs526770531 | 68 | R>Q | No | EVA | |
| rs483214143 | 69 | C>G | No | EVA | |
| rs462875600 | 70 | R>G | No | EVA | |
| rs460699541 | 75 | L>M | No | EVA | |
| rs440639245 | 77 | V>G | No | EVA | |
| rs472106092 | 78 | G>D | No | EVA | |
| rs438375506 | 80 | A>D | No | EVA | |
| rs458513036 | 80 | A>T | No | EVA | |
| rs476354428 | 82 | L>R | No | EVA | |
| rs456183648 | 85 | L>M | No | EVA | |
| rs442652150 | 87 | V>M | No | EVA | |
| rs453378732 | 91 | I>V | No | EVA | |
| rs465251143 | 100 | S>G | No | EVA | |
| rs714583820 | 101 | S>I | No | EVA | |
| rs451640453 | 106 | Q>K | No | EVA | |
| rs437947814 | 106 | Q>R | No | EVA | |
| rs518126563 | 112 | S>L | No | EVA |
No associated diseases with Q2KHY2
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| Golgi to plasma membrane protein transport | The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. |
| muscle organ development | The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGKELERCQ | RQADEVTEIM | LNNFDKVLER | DGKLAELEQR | SDQLLDMSSA | FSKTTKTLAQ |
| 70 | 80 | 90 | 100 | 110 | |
| KKRWENARCR | IYMGLAVGIA | LLILLIVLLV | IFLPQSSKGS | SAPQVQDAGP | ASGPGE |