Q28H65
Gene name |
foxn5 |
Protein name |
Forkhead box protein N5 |
Names |
|
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:733531 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q28H65
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q28H65-F1 | Predicted | AlphaFoldDB |
No variants for Q28H65
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q28H65 | |||||
No associated diseases with Q28H65
4 regional properties for Q28H65
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 119 - 404 | IPR000719 |
| active_site | Serine/threonine-protein kinase, active site | 240 - 252 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 125 - 149 | IPR017441 |
| domain | Glycogen synthase kinase 3, catalytic domain | 114 - 407 | IPR039192 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| sequence-specific double-stranded DNA binding | Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P32031 | slp2 | Fork head domain transcription factor slp2 | Drosophila melanogaster (Fruit fly) | PR |
| O15353 | FOXN1 | Forkhead box protein N1 | Homo sapiens (Human) | PR |
| Q96NZ1 | FOXN4 | Forkhead box protein N4 | Homo sapiens (Human) | PR |
| Q08050 | FOXM1 | Forkhead box protein M1 | Homo sapiens (Human) | EV |
| Q12948 | FOXC1 | Forkhead box protein C1 | Homo sapiens (Human) | PR |
| Q8K3Q3 | Foxn4 | Forkhead box protein N4 | Mus musculus (Mouse) | PR |
| Q61572 | Foxc1 | Forkhead box protein C1 | Mus musculus (Mouse) | PR |
| O08696 | Foxm1 | Forkhead box protein M1 | Mus musculus (Mouse) | PR |
| P97691 | Foxm1 | Forkhead box protein M1 | Rattus norvegicus (Rat) | PR |
| A2BGM5 | foxn4 | Forkhead box protein N4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYLRFANRKP | YEKLHLSTAL | EDWDMSEELK | LSITADQYFA | GADDKVERYT | LRRQHSTEVS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PTRSEEGDYQ | ECTFRPSLWL | VVDPNLVIPC | PEWINRIPPE | PELTSPPLQL | QRQLSNDYST |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEDSEDEAPT | SCSDVLTDDD | DSYNPWQPKH | KRKKAKCLGK | KLRVQKGLTQ | LESWPRPPLN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YCNLISLALR | NSEDGSLNVQ | QIYSFVREHF | PFFRIAPDGW | KNTVRHNLCF | SSSFEKSSGW |
| 250 | 260 | 270 | 280 | 290 | |
| VCADGHRRSC | LWKLTRQGRR | KFRNEMHALS | DDLLHVLRKS | MKKPALMELM | FGM |