Q21109

PR
Gene name
endu-1
Protein name
Endoribonuclease endu-1
Names
Poly(U)-specific endoribonuclease homolog, Uridylate-specific endoribonuclease homolog
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_K02A11.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-145 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21109

Entry ID Method Resolution Chain Position Source
AF-Q21109-F1 Predicted AlphaFoldDB

No variants for Q21109

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21109

No associated diseases with Q21109

4 regional properties for Q21109

Type Name Position InterPro Accession
domain K Homology domain, type 2 199 - 285 IPR004044
domain Small GTP-binding protein domain 9 - 166 IPR005225
domain GTP binding domain 12 - 126 IPR006073
domain Era-type guanine nucleotide-binding (G) domain 7 - 176 IPR030388

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

4 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
metal ion binding Binding to a metal ion.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
B1H3D5 endou Poly(U)-specific endoribonuclease Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q503V9 endoub Uridylate-specific endoribonuclease B Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MCSVLIFISI LTVLAQCQKI PRFDVSNSEL LAMAQKLRQV DTNRARPDQI KLNYQGHTVT
70 80 90 100 110 120
RDDSDAAQAK LFSKVDTSLF RKPSYELYIN LMDNFNRQTG VIEPRVSQAE EKNEVGKFLD
130 140 150 160 170 180
YVLESRPMQE LYNWFKAKGH PIATSPQVFR FWIGQLWFSH YSRALGRPDT SGFEHVFIGE
190 200 210 220 230 240
AKNGEISGMH NWVRFYVLEN NRTENFDYKG FTVKRFNIMA ALKFTWDGLL KRAGSILIGT
250 260 270 280 290 300
SPEFDMALYT MCFLSRRGRE TCDVEFDGCP LQITSFEIMQ QNKVYIGSIY PTAGRITDQC
RAQNRFN