B1H3D5

PR
Gene name
endou
Protein name
Poly(U)-specific endoribonuclease
Names
Protein endoU, Uridylate-specific endoribonuclease, XendoU
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:100145603
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

8-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1H3D5

Entry ID Method Resolution Chain Position Source
AF-B1H3D5-F1 Predicted AlphaFoldDB

No variants for B1H3D5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1H3D5

No associated diseases with B1H3D5

1 regional properties for B1H3D5

Type Name Position InterPro Accession
domain EndoU ribonuclease, C-terminal 9 - 286 IPR018998

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
metal ion binding Binding to a metal ion.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q21109 endu-1 Endoribonuclease endu-1 Caenorhabditis elegans PR
Q503V9 endoub Uridylate-specific endoribonuclease B Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MESNRTRGLN HELSKLFNEL WDADENRMKA GKDYRISLQG KAGYVPAGSN QARDSASYPL
70 80 90 100 110 120
FQFVDEEKLR SRKTFATFIS LLDNYEMDTG VAEVVTPEEI AENNTFLDAI LETKVMKIAH
130 140 150 160 170 180
DYLVRKNQAK PSRNDFKAQL YTIWFQLYSR APGQGPDSCG FEHVFVGESK RGKEIMGLHN
190 200 210 220 230 240
WVQFYLQEKR KTIDYKGYVG RQNKSRPDHD DQVLNLQFSW KEMVKPIGSS FIGVSPEFEF
250 260 270 280 290
ALYTVVFLTS QEKMTREVVR VEEYEMQIVV NRHGRYIGTA YPVLLSTNNP DLY