Q20678
Gene name |
sec-3 (F52E4.7) |
Protein name |
Exocyst complex component 1 |
Names |
Exocyst complex component Sec3 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F52E4.7 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q20678
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q20678-F1 | Predicted | AlphaFoldDB |
No variants for Q20678
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q20678 | |||||
No associated diseases with Q20678
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphatidylinositol-4,5-bisphosphate binding | Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| Golgi to plasma membrane transport | The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| vesicle tethering involved in exocytosis | The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAIRKIIQR | QLFQKDDERI | QAIVNVSKLD | GKKKKNQTLL | CLAVTIEHPI | AVRLYFVKGE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KDDTFKKKDR | FNLREVREID | GINPKKASPE | FHITIGDHQY | VILAGSAEEK | DEFIRELYKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SCQYLPVQMP | DFCNFSLPQL | ESETSIIPIE | LPEHDMAMQS | DYQPISNKED | ADFRKLIARA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NLTIGEAHIF | AEMLTEQLQS | LDGANINSMM | DSENSVNQLL | SSIDAALTGV | ESVEKELDRC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DDILAFVRNS | IELIEEKDSL | SVVERKNKQR | LNEEIVSFVN | SLQAVTDSHI | ETLKQANFSN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PESVQRCTDA | ARAVAQFWHG | RISKPMLQMK | AYQDRNDELT | AVDVFVDRLM | SHLSALFSNL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NDLSLDHEWH | ELCIPKQSQR | FRALSPLSDL | INWLKTNRPK | ACNLVLQKYI | DSTNLLYKRL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FDNFFETLIN | KVPKANSSEK | KSKANESANI | SLRSDNQSFL | STSSEIDTEV | LPQLIETVLA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ELSAVIDAEQ | KFVVRFFHIN | SELLAQFDTT | STGSGDSSSL | GGRSMEKHMN | EQVRHVMGNL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FDSLNIHLDS | FCRAVCRHNP | SNVLLLFVIM | SKKVLLPQDP | SSYFSITFGS | LVVLIKRQFD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AFIQMECSQY | SEVRIAKKTR | IGILPSIFRF | ANFVRRAEII | FENAERRTDL | EKAYFNLCRA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VCDGIQKAAA | NQYSKSPSSV | VKFENYHELY | LTLSELKISC | LDQQRKDAKA | LKEEHIDAYV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KEFMGRPLKE | IQTFFDNVNN | FIETRGIRPD | EISYQQQFSR | IELKKVISQH | PGKEVKKGLE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QLYKKIEKNL | VANSSLLQVV | WRDMQEQFVK | QIAEYNKLIL | TCYPGSKIEL | EVSTDTVLQF |
| FSEIAQQH |