Q20585

PR
Gene name
rpn-7 (F49C12.8)
Protein name
26S proteasome non-ATPase regulatory subunit 6
Names
26S proteasome regulatory subunit rpn-7
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F49C12.8
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q20585

Entry ID Method Resolution Chain Position Source
AF-Q20585-F1 Predicted AlphaFoldDB

No variants for Q20585

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q20585

No associated diseases with Q20585

2 regional properties for Q20585

Type Name Position InterPro Accession
domain Proteasome component (PCI) domain 207 - 394 IPR000717
domain 26S proteasome regulatory subunit Rpn7, N-terminal 81 - 253 IPR045135

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
proteasome regulatory particle A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.

1 GO annotations of molecular function

Name Definition
enzyme regulator activity Binds to and modulates the activity of an enzyme.

1 GO annotations of biological process

Name Definition
proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9GS00 csn-1 COP9 signalosome complex subunit 1 Caenorhabditis elegans PR
10 20 30 40 50 60
MTEAAKKSTK KPVDDGNFDK EIISRWPDLE LSQTRFMLNH PEVDSSVKEA KLEKLQETIK
70 80 90 100 110 120
EFDMAPFYEL VCADFKIVVD ATQLAAMKAA NQKKIDEITA EVEDAEKNLG ESEVRQGLLR
130 140 150 160 170 180
KFEYYCQIGD KDNALKAYTA TYEKTVGMGY RIDVVFAMIR VGLFFLDHHL INKFITKAKE
190 200 210 220 230 240
LMEQGGDWER KNRLRSYEAL YRMSVRDFAG AADLFLEAVP TFGSYELMTY ENLILYTVIT
250 260 270 280 290 300
TTFALDRPDL RTKVIRCNEV QEQLTGGGLN GTLIPVREYL ESYYDCHYDR FFIQLAALES
310 320 330 340 350 360
ERFKFDRYLS PHFNYYSRGM RHRAYEQFLT PYKTVRIDMM AKDFGVSRAF IDRELHRLIA
370 380 390 400
TGQLQCRIDA VNGVIEVNHR DSKNHLYKAV IKDGDILLNR IQKLARVINA