Q19262
Gene name |
sec-6 (F09E5.5) |
Protein name |
Exocyst complex component 3 |
Names |
Exocyst complex component Sec6 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F09E5.5 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q19262
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q19262-F1 | Predicted | AlphaFoldDB |
No variants for Q19262
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q19262 | |||||
No associated diseases with Q19262
No regional properties for Q19262
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q19262 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| SNARE binding | Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| exocyst localization | Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| vesicle tethering involved in exocytosis | The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9V8K2 | Sec6 | Exocyst complex component 3 | Drosophila melanogaster (Fruit fly) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDVDVEEAAL | EQVAALLQRP | DQLEKLPELK | KRADRKKLAV | EAMLRTGVQG | QLEGIRTAIA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HLQTASDDIT | AISQGVHDIR | ERLGPFPQLK | EKLRELRDAN | ARHGQYAAAM | ENLKHIFNLQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TTLQEIRDAL | DDEKSGGNLL | LAHKHIMDLE | RARDELLAEV | HKMSGTNTEK | EQMLLVNFFK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVDSVVAELS | KNMWFILGRT | LEMVKGNEQG | GGPQQVVTCL | RIVEREERID | KFYMEARSKN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSAFVPPGRP | RNWKEKALRS | LEKTVSNRVD | GNQLEDRSLN | KAWLARYLEV | CKNVIMDDLQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAKVAIPCFP | PDWQIYDRYV | HMYHTSVCRR | LREVASEHLE | KSELVQLMSW | IKFYASEDML |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GHPKLRINAQ | AILQDSPVLS | RSTLNQLCDQ | FVEMSRDDLK | LWLKNTVSHE | THDWYKNLRP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SEDNHGYFYT | DLPNTVFGML | KDTVTLAKEV | SVEVIPSIIN | LTIQEFNELA | GKYRDAFTAY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KTDYFAERSK | YQEFTSNIIA | IANNLHTCIE | STEKYKQQIR | LSMEGEQNAA | AAMTTPLASG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RRTAVRQQQL | IENMDALNTK | WSNAASVAVN | YLREEVITDI | APSLVEIFSK | KWLTGSAALE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TVCMTISDYY | HDHKHLRPVT | RSTLLMDLQF | RIVSEYLKAI | ETKRVSLNSY | EERALAGKRM |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KADVVRLDNL | YAEFATSSDM | ADQLPLLTSI | VAAAGDVISL | KDKSLLSLEA | TSFARKFPNC |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PAELLSAVIA | TRDDISGSEA | RSLASEVLQH | VQFHPKDQIF | DQLFALRQQE | NSERLPNLGM |
| 790 | |||||
| ANMFKADFMS | MLKRDA |