AiPD: Autoinhibited Protein Database

Q15021

Gene name	NCAPD2
Protein name	Condensin complex subunit 1
Names	Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, hCAP-D2, Non-SMC condensin I complex subunit D2, XCAP-D2 homolog
Species	Homo sapiens (Human)
KEGG Pathway	hsa:9918
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

543-618 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

543-618 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q15021

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q15021-F1	Predicted				AlphaFoldDB

1186 variants for Q15021

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
VAR_080953	8	F>S	MCPH21; found in two patients from a consanguineous family; unknown pathological significance [UniProt]	Yes	UniProt
CA6408314 rs576859525 RCV001331914	389	T>I	Microcephaly 21, primary, autosomal recessive [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
rs145893978 CA6408424 RCV001331915	509	N>S	Microcephaly 21, primary, autosomal recessive [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
CA6408816 RCV002533882 rs762710261 RCV000761815	883	E>K	Variant assessed as Somatic; 0.0 impact. Inborn genetic diseases [NCI-TCGA, ClinVar]	Yes	ClinGen ClinVar ExAC NCI-TCGA TOPMed dbSNP gnomAD
RCV001331975 rs1946356525	1277	E>V	Microcephaly 21, primary, autosomal recessive [ClinVar]	Yes	ClinVar dbSNP
rs149571298 CA6407905	2	A>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs149571298 CA383566583	2	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144221350 CA6407906	3	P>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA383566591 rs144221350	3	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6407907 rs368305298	5	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs886677060 CA232373222	6	Y>D		No	ClinGen Ensembl
CA383566667 rs1350540486	8	F>C		No	ClinGen gnomAD
CA6407908 rs745475144	9	H>R		No	ClinGen ExAC TOPMed gnomAD
CA383566730 rs1296559231	13	S>F		No	ClinGen gnomAD
rs148279081 CA6407909	15	E>K		No	ClinGen ESP ExAC TOPMed
rs777110079 CA6407910	15	E>V		No	ClinGen ExAC TOPMed gnomAD
CA383566764 rs1177496044	16	E>K		No	ClinGen TOPMed
CA383566871 rs371605695	22	G>E		No	ClinGen ESP gnomAD
CA232373250 rs371605695	22	G>V		No	ClinGen ESP gnomAD
CA383566889 rs1592162468	23	V>G		No	ClinGen Ensembl
CA6407914 rs61753197	23	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6407915 rs766383936	24	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1284721438 CA383566928	25	Q>H		No	ClinGen gnomAD
rs781325895 CA6407916	26	Y>C		No	ClinGen ExAC gnomAD
CA383566932 rs1488373909	26	Y>H		No	ClinGen gnomAD
CA383566957 rs1473056661	28	V>L		No	ClinGen TOPMed
CA232373266 rs887007094	30	E>G		No	ClinGen TOPMed
TCGA novel	31	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759709281 CA6407917	31	V>L		No	ClinGen ExAC gnomAD
CA6407919 rs752405691	34	I>V		No	ClinGen ExAC gnomAD
CA383567090 rs756144447	35	K>I		No	ClinGen ExAC TOPMed gnomAD
rs756144447 CA6407920	35	K>R		No	ClinGen ExAC TOPMed gnomAD
rs753741130 CA6407922	36	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA6407921 rs368159489	36	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA383567176 rs1420522627	40	Q>P		No	ClinGen TOPMed gnomAD
CA383567196 rs1357181080	41	L>F		No	ClinGen TOPMed gnomAD
rs139616215 CA6407951	43	A>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs139616215 CA6407952	43	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6407953 rs530151221	44	F>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383562254 rs1245055627	47	A>D		No	ClinGen TOPMed gnomAD
CA383562259 rs1245055627	47	A>V		No	ClinGen TOPMed gnomAD
rs550146120 CA6407955	49	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs550146120 CA6407956	49	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6407957 rs775605375	49	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA383562296 rs1565541020	51	Q>E		No	ClinGen Ensembl
rs760900534 CA6407958	51	Q>R		No	ClinGen ExAC
CA383562327 rs1276479494	53	P>S		No	ClinGen TOPMed
rs1341604062 CA383562340	55	A>T		No	ClinGen gnomAD
CA383562363 rs1565541034	56	M>I		No	ClinGen Ensembl
rs570257017 CA6407960	56	M>V		No	ClinGen 1000Genomes ExAC gnomAD
CA6407962 rs776454415	63	I>F		No	ClinGen ExAC gnomAD
rs147643090 CA6407963	63	I>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA383562479 rs776454415	63	I>V		No	ClinGen ExAC gnomAD
CA6407965 rs750325794	64	Y>C		No	ClinGen ExAC gnomAD
CA232384843 rs750325794	64	Y>F		No	ClinGen ExAC gnomAD
rs750602915 CA6407959	64	Y>G		No	ClinGen ExAC
CA232384844 rs760738086	67	L>V		No	ClinGen Ensembl
rs552513216 CA6407968	67	L>W		No	ClinGen 1000Genomes ExAC gnomAD
rs1038935656 CA232384873	69	H>L		No	ClinGen Ensembl
CA6407984 rs766616615	71	R>*		No	ClinGen ExAC gnomAD
rs200920120 CA6407985 COSM1239554	71	R>Q	Variant assessed as Somatic; 0.0 impact. oesophagus large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs370628893 CA6407987	73	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA6407986 rs765860532	73	I>T		No	ClinGen ExAC gnomAD
rs1565541157 CA383562724	74	D>G		No	ClinGen Ensembl
CA232384875 rs868593641	75	P>A		No	ClinGen TOPMed
CA232384874 rs868593641	75	P>T		No	ClinGen TOPMed
rs1185299652 CA383562838	82	L>V		No	ClinGen TOPMed gnomAD
rs714774 CA383562843	83	Q>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs714774 VAR_024421 CA6407989	83	Q>E		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs714774 CA383562842	83	Q>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA383562896 rs1164863276	86	I>M		No	ClinGen gnomAD
CA232384905 rs79122711	90	S>P		No	ClinGen Ensembl
rs761217214 CA6408088	91	R>C		No	ClinGen ExAC TOPMed gnomAD
rs12424437 CA6408089	91	R>H		No	ClinGen ExAC TOPMed gnomAD
CA383563394 rs1232384445	93	S>F		No	ClinGen gnomAD
CA383563406 rs1487479800	94	Q>L		No	ClinGen TOPMed
rs762152072 CA6408091	98	A>G		No	ClinGen ExAC TOPMed gnomAD
rs1422757934 CA383563473	99	I>V		No	ClinGen TOPMed gnomAD
rs766111488 CA6408095	101	D>G		No	ClinGen ExAC gnomAD
CA6408093 rs750588842	101	D>H		No	ClinGen ExAC TOPMed gnomAD
CA6408094 rs750588842	101	D>N		No	ClinGen ExAC TOPMed gnomAD
rs149674449 CA232384906	102	D>A		No	ClinGen ESP TOPMed gnomAD
CA383563523 rs149674449	102	D>G		No	ClinGen ESP TOPMed gnomAD
CA383563541 rs1490709888	103	T>K		No	ClinGen TOPMed gnomAD
CA232384908 rs780825688	112	A>S		No	ClinGen ExAC gnomAD
CA6408098 COSM942588 rs780825688	112	A>T	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1344007333 CA383563645	115	N>Y		No	ClinGen gnomAD
CA232384909 rs963200806	119	M>K		No	ClinGen TOPMed
CA6408099 rs747602621	120	N>D		No	ClinGen ExAC gnomAD
rs1425753082 CA383563709	124	L>V		No	ClinGen TOPMed
CA6408101 rs777295465	125	I>T		No	ClinGen ExAC gnomAD
rs1367844781 CA383563719	126	R>C		No	ClinGen TOPMed
rs748909515 CA6408102 COSM1216785	126	R>H	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA383563723 rs748909515	126	R>L		No	ClinGen ExAC gnomAD
CA383563725 rs1166992985	127	L>V		No	ClinGen TOPMed
CA6408103 rs772587843	130	S>F		No	ClinGen ExAC gnomAD
CA383563753 rs1206859786	131	F>S		No	ClinGen gnomAD
rs574851318 CA6408104	132	E>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs886121001 CA383563761	132	E>D		No	ClinGen gnomAD
TCGA novel	133	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761677659 CA6408105	133	T>N		No	ClinGen ExAC TOPMed gnomAD
rs761677659 CA383563766	133	T>S		No	ClinGen ExAC TOPMed gnomAD
CA383563765 rs1373814489	133	T>S		No	ClinGen TOPMed
rs1200050622 CA383563771	134	M>T		No	ClinGen TOPMed
rs372285001 CA232384912	134	M>V		No	ClinGen Ensembl
rs1431180887 CA383563781	135	A>V		No	ClinGen gnomAD
rs1565541527 CA383563810	137	Q>H		No	ClinGen Ensembl
CA383563812 rs769029337	138	T>A		No	ClinGen ExAC TOPMed gnomAD
rs769029337 CA6408106	138	T>P		No	ClinGen ExAC TOPMed gnomAD
rs1167331822 CA383563865	140	L>R		No	ClinGen gnomAD
CA383563930 rs1365924439	143	L>V		No	ClinGen gnomAD
CA383563958 rs1364528190	144	D>N		No	ClinGen gnomAD
CA6408109 rs761803417	145	L>F		No	ClinGen ExAC TOPMed gnomAD
CA383563991 rs761803417	145	L>I		No	ClinGen ExAC TOPMed gnomAD
rs761803417 CA383563989	145	L>V		No	ClinGen ExAC TOPMed gnomAD
CA6408110 rs769874103	146	G>A		No	ClinGen ExAC gnomAD
rs773442258 CA6408111	147	G>R		No	ClinGen ExAC gnomAD
rs374658418 CA6408112	148	K>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA383564984 rs1241950713	149	G>D		No	ClinGen gnomAD
CA383565002 rs1264359465	150	K>E		No	ClinGen gnomAD
CA6408134 rs546615712	152	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6408135 rs566781375	153	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383565072 rs1431522943	153	R>W		No	ClinGen TOPMed
rs149220411 CA232384971	155	K>N		No	ClinGen ESP TOPMed gnomAD
CA232384973 rs995954491	156	A>V		No	ClinGen Ensembl
CA232384975 rs753271642	157	A>D		No	ClinGen TOPMed
CA383565117 rs753271642	157	A>V		No	ClinGen TOPMed
rs1384416154 CA383565140	158	H>L		No	ClinGen gnomAD
rs763738810 CA6408137	159	G>S		No	ClinGen ExAC TOPMed gnomAD
rs753383625 CA6408138	160	F>Y		No	ClinGen ExAC gnomAD
CA6408139 rs756767693	161	D>E		No	ClinGen ExAC gnomAD
rs1453406635 CA383565174	161	D>N		No	ClinGen gnomAD
rs1334140744 CA383565234	163	E>K		No	ClinGen gnomAD
rs778711579 CA6408140	164	E>V		No	ClinGen ExAC gnomAD
rs750056098 CA6408141	165	E>G		No	ClinGen ExAC TOPMed gnomAD
CA383565365 rs1418298003	167	Q>H		No	ClinGen TOPMed
CA6408142 rs535712146	169	I>V		No	ClinGen 1000Genomes ExAC gnomAD
CA383565430 rs1262373982	171	Q>H		No	ClinGen TOPMed gnomAD
rs781594197 CA6408143	171	Q>K		No	ClinGen ExAC TOPMed gnomAD
rs1461734101 CA383565512	174	T>I		No	ClinGen TOPMed gnomAD
rs748640904 CA6408144	175	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs373617147 CA6408145	177	L>F		No	ClinGen ESP ExAC gnomAD
rs777889802 CA6408146	178	Q>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA232384989 rs892987814	180	D>N		No	ClinGen TOPMed gnomAD
rs774592106 CA6408149	182	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6408150 rs746054013	182	R>H		No	ClinGen ExAC TOPMed gnomAD
rs771813237 CA6408151	183	H>R		No	ClinGen ExAC gnomAD
rs1304604179 CA383565832	186	N>S		No	ClinGen gnomAD
CA383565845 rs1394499311	187	H>Y		No	ClinGen gnomAD
CA383565872 rs1273077875	188	S>T		No	ClinGen TOPMed
rs1308035813 CA383565886	189	I>V		No	ClinGen TOPMed gnomAD
CA6408155 rs776642083	190	I>L		No	ClinGen ExAC gnomAD
rs1299857568 CA383565923	190	I>T		No	ClinGen gnomAD
rs200260523 CA232385001	192	E>D		No	ClinGen Ensembl
CA232385003 rs146876646	193	E>K		No	ClinGen ESP TOPMed gnomAD
rs201246236 CA232385006	195	V>A		No	ClinGen Ensembl
CA6408156 rs761438809	195	V>F		No	ClinGen ExAC gnomAD
rs1221357870 CA383567377	197	L>F		No	ClinGen gnomAD
CA383567358 rs1365604326	197	L>M		No	ClinGen TOPMed
rs200251936 CA6408173	201	C>W		No	ClinGen ExAC gnomAD
CA6408175 rs764879490	202	C>*		No	ClinGen ExAC gnomAD
CA6408174 rs764879490	202	C>W		No	ClinGen ExAC gnomAD
rs201733141 CA6408176	204	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs374598691 CA6408177	204	R>H		No	ClinGen ExAC TOPMed gnomAD
rs374598691 CA383567504	204	R>P		No	ClinGen ExAC TOPMed gnomAD
CA6408180 rs756503239	210	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
COSM3955060 rs756503239 CA383567618	210	T>S	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs372201069 CA383567684	213	H>D		No	ClinGen TOPMed
TCGA novel	213	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs372201069 CA232385710	213	H>Y		No	ClinGen TOPMed
rs540954737 CA232385711	214	Q>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs540954737 CA6408181	214	Q>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs202035339 CA6408182	217	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs202035339 CA383567781	217	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs757733418 CA6408183	217	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs201537317 CA6408184	218	P>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6408185 rs192594761	219	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383567841 rs780351586	220	R>G		No	ClinGen ExAC TOPMed gnomAD
CA383567846 rs201003099	220	R>L		No	ClinGen ExAC TOPMed gnomAD
CA6408188 rs201003099	220	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA6408187 rs780351586	220	R>W		No	ClinGen ExAC TOPMed gnomAD
CA6408189 rs768621167	221	E>K		No	ClinGen ExAC gnomAD
rs969476476 CA232385713	227	L>F		No	ClinGen Ensembl
rs748161516 CA6408191	228	G>A		No	ClinGen ExAC TOPMed gnomAD
rs140685494 CA232385714	228	G>R		No	ClinGen ESP
rs1480503391 CA383568015	229	V>L		No	ClinGen TOPMed
CA6408193 rs772966919	230	A>S		No	ClinGen ExAC TOPMed gnomAD
rs1310626272 CA383568033	230	A>V		No	ClinGen TOPMed
CA6408195 rs770307249	231	L>V		No	ClinGen ExAC gnomAD
rs759171639 CA383568074	232	T>I		No	ClinGen ExAC TOPMed gnomAD
CA6408196 rs774076450	232	T>P		No	ClinGen ExAC gnomAD
rs759171639 CA6408197	232	T>S		No	ClinGen ExAC TOPMed gnomAD
rs774076450 CA383568070	232	T>S		No	ClinGen ExAC gnomAD
rs764486667 CA6408198	233	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6408199 rs754200286	233	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1299602043 CA383568135	237	M>I		No	ClinGen TOPMed
rs201164765 CA6408201	237	M>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs750852571 CA6408202	237	M>T		No	ClinGen ExAC TOPMed gnomAD
rs201164765 CA383568128	237	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383568153 rs1454247720	239	S>G		No	ClinGen gnomAD
rs956412691 CA232385721	244	I>T		No	ClinGen TOPMed gnomAD
rs1403727114 CA383568271	245	I>F		No	ClinGen gnomAD
CA383568276 rs1482429557	245	I>T		No	ClinGen TOPMed
CA383568312 rs1211770225	247	M>I		No	ClinGen TOPMed
CA383568305 rs1279840454	247	M>L		No	ClinGen TOPMed
CA383568324 rs1565542735	248	L>P		No	ClinGen Ensembl
CA383568382 rs1592171191	253	H>P		No	ClinGen Ensembl
CA6408217 rs762193347	254	L>P		No	ClinGen ExAC gnomAD
CA383568396 rs1439529085	255	A>V		No	ClinGen gnomAD
CA383568399 rs1278640183	256	P>S		No	ClinGen gnomAD
rs989028406 CA232385725	259	V>A		No	ClinGen TOPMed gnomAD
rs1336235743 CA383568425	260	A>V		No	ClinGen TOPMed
CA6408222 rs200088499	262	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs970529615 CA232385727	263	S>R		No	ClinGen TOPMed
CA383568445 rs1203651851	264	L>V		No	ClinGen TOPMed gnomAD
TCGA novel	266	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1436134351 CA383568468	267	T>I		No	ClinGen TOPMed
CA6408224 rs767859123	268	D>E		No	ClinGen ExAC TOPMed gnomAD
CA6408226 rs755960209	269	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA6408228 rs749292483	270	G>E		No	ClinGen ExAC gnomAD
CA6408229 rs201656263	271	M>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1257145371 CA383568520	274	I>T		No	ClinGen TOPMed
CA232385730 rs926307259	275	V>A		No	ClinGen TOPMed
CA6408232 rs556672612	276	G>R		No	ClinGen 1000Genomes ExAC gnomAD
rs756547882 CA6408230	277	E>*		No	ClinGen ExAC TOPMed
TCGA novel	277	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771528727 CA6408233	277	E>K		No	ClinGen ExAC gnomAD
rs1277758609 CA383568547	278	I>T		No	ClinGen Ensembl
rs1486737685 CA383568551	279	V>I		No	ClinGen TOPMed
rs1324618252 CA383568590	282	I>M		No	ClinGen gnomAD
rs140976120 CA6408251	285	K>N		No	ClinGen ESP ExAC gnomAD
CA6408250 rs778850762	285	K>Q		No	ClinGen ExAC gnomAD
rs757948141 CA6408252	286	C>R		No	ClinGen ExAC gnomAD
rs1230855012 CA383568632	289	E>K		No	ClinGen gnomAD
CA6408254 rs746741464	292	R>*		No	ClinGen ExAC gnomAD
CA6408255 rs150197479	292	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA383568689 rs1477424711	293	D>G		No	ClinGen gnomAD
rs1191451804 CA383568721 COSM298475	295	S>*	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1445197798 CA383568782	299	G>D		No	ClinGen gnomAD
CA383568807 rs1192467161	301	A>S		No	ClinGen TOPMed gnomAD
rs1192467161 CA383568804	301	A>T		No	ClinGen TOPMed gnomAD
CA6408258 rs764547668	302	A>G		No	ClinGen ExAC TOPMed gnomAD
CA6408259 rs775022978	305	T>I		No	ClinGen ExAC gnomAD
CA383568898 rs760098665	307	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1592171338 CA383568909	308	A>T		No	ClinGen Ensembl
TCGA novel	309	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408261 rs767746417	310	R>C		No	ClinGen ExAC TOPMed gnomAD
rs775710530 CA6408262	310	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6408263 rs761020034	311	V>I		No	ClinGen ExAC gnomAD
rs754028921 CA383568973	312	P>A		No	ClinGen ExAC gnomAD
rs754028921 CA6408265	312	P>S		No	ClinGen ExAC gnomAD
CA6408266 rs761533440	313	A>S		No	ClinGen ExAC gnomAD
CA383569049 rs1417711545	317	S>C		No	ClinGen TOPMed
CA6408268 rs750396738	317	S>P		No	ClinGen ExAC gnomAD
TCGA novel	318	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383569074 rs1167571753	319	M>V		No	ClinGen TOPMed
CA6408269 rs758323988	320	C>Y		No	ClinGen ExAC gnomAD
rs779596854 CA6408270	321	I>V		No	ClinGen ExAC
CA6408271 rs751045122	325	H>D		No	ClinGen ExAC gnomAD
CA6408272 rs754442022	329	E>K		No	ClinGen ExAC gnomAD
CA383570342 rs1347764272	330	N>K		No	ClinGen TOPMed gnomAD
CA6408286 rs750204852	330	N>S		No	ClinGen ExAC gnomAD
rs1201695635 CA383570321	330	N>Y		No	ClinGen gnomAD
CA383570386 rs1170651681	332	M>V		No	ClinGen TOPMed
rs762678605 CA6408287	334	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6408288 rs771302335	334	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	334	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408290 rs143795587	337	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6408289 RCV000923232 rs143795587	337	V>M		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA232386321 rs537119663	341	M>V		No	ClinGen 1000Genomes TOPMed
rs781501861 CA232386322	342	A>E		No	ClinGen TOPMed gnomAD
CA383570619 rs781501861	342	A>V		No	ClinGen TOPMed gnomAD
rs147023142 CA6408292	344	M>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1466574928 CA383570640	344	M>V		No	ClinGen gnomAD
CA6408294 rs779481219	346	L>P		No	ClinGen ExAC gnomAD
CA6408295 rs779481219	346	L>R		No	ClinGen ExAC gnomAD
CA6408297 rs772501599	348	V>A		No	ClinGen ExAC gnomAD
CA383570680 rs772501599	348	V>G		No	ClinGen ExAC gnomAD
CA232386330 rs748279493	350	S>R		No	ClinGen Ensembl
rs370387241 CA232386335	352	D>G		No	ClinGen TOPMed
rs994613441 CA383570705	352	D>H		No	ClinGen TOPMed gnomAD
rs994613441 CA232386333	352	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA232386341 rs1027786615	354	L>V		No	ClinGen Ensembl
rs138198563 CA6408299	358	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs768655520 CA6408300	359	R>*		No	ClinGen ExAC gnomAD
CA6408301 rs776764263	359	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6408302 rs762076491	361	T>I		No	ClinGen ExAC gnomAD
CA232386353 rs1016312186	362	R>T		No	ClinGen TOPMed
rs886280771 CA232386355	366	L>F		No	ClinGen Ensembl
CA6408305 rs773356519	367	D>V		No	ClinGen ExAC
rs770015862 CA6408303	367	D>Y		No	ClinGen ExAC TOPMed gnomAD
rs1190344409 CA383570890	369	L>S		No	ClinGen TOPMed gnomAD
CA383570886 rs1478230124	369	L>V		No	ClinGen TOPMed gnomAD
CA383570902 rs1413793943	370	Q>*		No	ClinGen TOPMed
CA383570983 rs1267228317	373	G>V		No	ClinGen gnomAD
CA383570990 rs1434263101	374	H>D		No	ClinGen gnomAD
CA383571003 rs1425633175	374	H>R		No	ClinGen TOPMed
CA232386365 rs756476624	375	D>H		No	ClinGen gnomAD
TCGA novel	376	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383571069 rs1371471081	377	N>S		No	ClinGen gnomAD
rs778053909 CA6408307	378	S>A		No	ClinGen ExAC TOPMed gnomAD
rs767003306 CA6408310 COSM1639207	381	R>Q	stomach [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA6408309 rs759487830	381	R>W		No	ClinGen ExAC gnomAD
rs1410769857 CA383571846	382	S>R		No	ClinGen TOPMed
CA6408312 rs1555139353	383	R>C		No	ClinGen Ensembl
CA383571850 rs1565543541	383	R>H		No	ClinGen Ensembl
rs1368142678 CA383571899	386	Q>H		No	ClinGen gnomAD
CA383571937 rs576859525	389	T>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383571938 rs576859525	389	T>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1325388960 COSM3356344 CA383572014	390	R>*	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs369341180 CA6408316	390	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408317 COSM942591 rs369341180	390	R>Q	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	391	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383572091 rs1356869496	393	Q>R		No	ClinGen gnomAD
CA6408318 rs780431663	394	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs1181563069 CA383572284	396	A>P		No	ClinGen gnomAD
rs756233720 CA6408341	396	A>V		No	ClinGen ExAC gnomAD
TCGA novel	399	L>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs143666333 CA383572344	399	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408343 rs749581234	399	L>P		No	ClinGen ExAC gnomAD
rs143666333 CA383572341	399	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA383572360 rs1457721024	400	T>A		No	ClinGen gnomAD
rs968525819 CA232387749	400	T>I		No	ClinGen TOPMed gnomAD
CA383572366 rs968525819	400	T>K		No	ClinGen TOPMed gnomAD
CA383572370 rs968525819	400	T>R		No	ClinGen TOPMed gnomAD
CA6408345 rs771172038	401	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6408344 rs771172038	401	R>G		No	ClinGen ExAC TOPMed gnomAD
rs745684361 CA6408346	401	R>H		No	ClinGen ExAC gnomAD
rs745684361 CA383572385	401	R>P		No	ClinGen ExAC gnomAD
rs775593732 CA6408348	402	F>L		No	ClinGen ExAC TOPMed gnomAD
CA6408349 rs760671057	405	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1329055901 CA383572468	406	V>M		No	ClinGen gnomAD
rs549180267 CA6408350	407	A>V		No	ClinGen 1000Genomes ExAC gnomAD
CA6408351 CA232387762 rs77013243	408	L>F		No	ClinGen ExAC gnomAD
CA383572508 rs1209521325	409	A>G		No	ClinGen gnomAD
CA6408352 rs761167790	409	A>T		No	ClinGen ExAC gnomAD
CA6408353 rs201272617	412	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs924298728 CA232387767	412	R>H		No	ClinGen TOPMed gnomAD
CA383572576 rs924298728	412	R>L		No	ClinGen TOPMed gnomAD
rs759967466 CA6408355	414	A>P		No	ClinGen ExAC gnomAD
CA383572631 rs1161362028	415	D>E		No	ClinGen gnomAD
CA6408356 rs375941071	416	K>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA383572648 rs1413344653	416	K>T		No	ClinGen gnomAD
CA232387772 rs756609653	418	V>A		No	ClinGen ExAC gnomAD
CA6408358 rs756609653	418	V>G		No	ClinGen ExAC gnomAD
CA383572737 rs1592172460	421	C>*		No	ClinGen Ensembl
CA6408359 rs538027698	421	C>R		No	ClinGen 1000Genomes ExAC gnomAD
CA383572734 rs1350326693	421	C>Y		No	ClinGen TOPMed gnomAD
CA383572743 rs1592172461	422	K>T		No	ClinGen Ensembl
rs1592172465 CA383572777	424	A>P		No	ClinGen Ensembl
TCGA novel	424	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1592172468 CA383572803	425	I>T		No	ClinGen Ensembl
CA383572910 rs1343497371	430	S>I		No	ClinGen gnomAD
CA6408362 rs200578810	435	N>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs746032928 CA6408363	435	N>S		No	ClinGen ExAC gnomAD
CA6408364 rs771954995	436	P>S		No	ClinGen ExAC gnomAD
CA6408365 rs779988202	438	S>F		No	ClinGen ExAC gnomAD
CA383573065 rs1431697126	439	C>R		No	ClinGen TOPMed
CA383573083 rs1406424119	439	C>Y		No	ClinGen gnomAD
CA6408375 rs760972801	441	L>F		No	ClinGen ExAC gnomAD
CA6408377 rs373603488	442	S>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs35272924 CA232387813	442	S>T		No	ClinGen Ensembl
rs778841033 CA6408379	446	L>F		No	ClinGen ExAC gnomAD
rs773211754 CA6408381	448	G>R		No	ClinGen ExAC TOPMed gnomAD
rs141181063 CA6408382	449	P>L		No	ClinGen ESP ExAC TOPMed
rs1182322584 CA383573299	451	Q>R		No	ClinGen TOPMed
CA6408385 rs768529470	452	K>N		No	ClinGen ExAC gnomAD
CA6408386 rs781299055	454	T>S		No	ClinGen ExAC gnomAD
TCGA novel	455	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM1216788 CA383573375 rs1265969872	456	K>Q	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1592172580 CA383573420	458	Q>*		No	ClinGen Ensembl
CA383573424 rs1389070012	458	Q>P		No	ClinGen TOPMed gnomAD
CA383573453 rs1227652166	459	E>D		No	ClinGen gnomAD
rs748013479 CA6408387	460	M>I		No	ClinGen ExAC gnomAD
rs1432943755 CA383573533	464	R>K		No	ClinGen gnomAD
COSM1639208 CA6408391 rs749028321	465	R>*	stomach [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA383573553 rs770586366	465	R>L		No	ClinGen ExAC TOPMed gnomAD
CA6408392 rs770586366	465	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1282208474 CA383573558 COSM942592	466	T>A	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1309035025 CA383573563	466	T>I		No	ClinGen gnomAD
TCGA novel	467	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1355453495 CA383573584	467	A>V		No	ClinGen gnomAD
rs374668663 CA6408393	469	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	471	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1465122570 CA383573689	471	A>V		No	ClinGen TOPMed
rs940447004 CA232387923	473	L>P		No	ClinGen gnomAD
CA383573768 rs1592172677	477	E>K		No	ClinGen Ensembl
CA6408412 rs769053029	478	E>D		No	ClinGen ExAC gnomAD
TCGA novel	478	E>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408413 rs776858241	479	W>S		No	ClinGen ExAC gnomAD
CA383573825 rs1592172683	480	E>K		No	ClinGen Ensembl
rs762176392 CA6408414	483	L>Q		No	ClinGen ExAC TOPMed gnomAD
CA6408415 rs765663001	485	E>G		No	ClinGen ExAC TOPMed gnomAD
rs773726183 CA6408416	486	L>W		No	ClinGen ExAC gnomAD
CA383573964 rs1401704535	487	K>T		No	ClinGen gnomAD
CA6408417 rs535745888	488	S>C		No	ClinGen 1000Genomes ExAC gnomAD
CA383573998 rs1335900412	489	T>I		No	ClinGen gnomAD
rs199590135 CA6408419	491	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408420 rs755245448	495	Q>*		No	ClinGen ExAC gnomAD
rs150719071 CA6408421	497	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1565543899 CA383574178	498	Q>K		No	ClinGen Ensembl
rs1327335415 CA383574303	501	E>D		No	ClinGen TOPMed
CA383574266 rs1230379033	501	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs752448560 CA6408423	508	A>S		No	ClinGen ExAC TOPMed gnomAD
rs1201891353 CA383574479	509	N>K		No	ClinGen TOPMed gnomAD
rs375796466 CA232387961	516	V>M		No	ClinGen TOPMed
CA6408425 rs777603676	517	K>N		No	ClinGen ExAC gnomAD
rs753729110 CA6408426	519	R>C		No	ClinGen ExAC TOPMed gnomAD
rs753729110 CA383574693	519	R>G		No	ClinGen ExAC TOPMed gnomAD
rs1374542456 CA383574698 COSM1216786	519	R>H	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed
rs753729110 CA383574685	519	R>S		No	ClinGen ExAC TOPMed gnomAD
rs756811614 CA383574707	520	I>L		No	ClinGen ExAC TOPMed gnomAD
CA6408428 rs778368343	520	I>T		No	ClinGen ExAC gnomAD
CA6408427 rs756811614	520	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1377178791 CA383574745	521	Y>C		No	ClinGen TOPMed gnomAD
rs1377178791 CA383574751	521	Y>F		No	ClinGen TOPMed gnomAD
rs745591282 CA6408429	522	Q>*		No	ClinGen ExAC gnomAD
CA383574809 rs1428787448	524	L>P		No	ClinGen TOPMed gnomAD
CA6408430 rs771633449	525	A>V		No	ClinGen ExAC TOPMed gnomAD
rs748489930 CA6408432	527	A>T		No	ClinGen ExAC gnomAD
CA383574902 rs1299989514	528	S>G		No	ClinGen gnomAD
rs1391369688 CA383576502	530	K>N		No	ClinGen gnomAD
CA383576537 rs1592174286	532	A>P		No	ClinGen Ensembl
rs1294796514 CA383576571	533	I>T		No	ClinGen gnomAD
CA232389238 rs368311206	533	I>V		No	ClinGen ESP TOPMed gnomAD
CA383576636 rs1592174293	536	T>P		No	ClinGen Ensembl
CA6408450 rs770092608	537	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA383576655 rs770092608	537	R>G		No	ClinGen ExAC TOPMed gnomAD
rs778277993 CA6408451	537	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs139063293 CA6408453	538	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs139063293 CA6408452	538	E>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs774933116 CA6408454	539	A>S		No	ClinGen ExAC TOPMed gnomAD
CA383576760 rs1265298375	540	T>R		No	ClinGen gnomAD
rs759567744 CA6408455	542	H>R		No	ClinGen ExAC gnomAD
CA383576835 rs1243357527	543	F>C		No	ClinGen gnomAD
rs146888515 CA232389253	543	F>L		No	ClinGen ESP TOPMed
rs143983696 CA6408456	543	F>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	544	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408457 rs775626136	545	E>K		No	ClinGen ExAC gnomAD
CA232389270 rs200077145	547	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA TOPMed gnomAD
CA383576984 rs1421764525	549	F>S		No	ClinGen gnomAD
CA383577005 rs1163848778	550	S>G		No	ClinGen gnomAD
CA383577052 rs753621723	551	H>L		No	ClinGen ExAC gnomAD
CA6408460 rs753621723	551	H>P		No	ClinGen ExAC gnomAD
CA6408463 rs750308942	552	I>T		No	ClinGen ExAC gnomAD
rs765186777 CA6408462	552	I>V		No	ClinGen ExAC gnomAD
rs757893568 CA6408464	554	P>L		No	ClinGen ExAC gnomAD
rs201687848 CA232389286	555	E>K		No	ClinGen 1000Genomes
rs751235646 CA6408466	558	E>K		No	ClinGen ExAC gnomAD
rs1336071300 CA383578068	561	R>K		No	ClinGen gnomAD
CA6408467 rs754644063	561	R>S		No	ClinGen ExAC gnomAD
rs1565544933 CA383578115	563	L>S		No	ClinGen Ensembl
CA6408470 rs749675666	565	I>V		No	ClinGen ExAC gnomAD
rs779587095 CA6408472	568	L>P		No	ClinGen ExAC gnomAD
rs1482413115 CA383578205	569	I>V		No	ClinGen gnomAD
CA232389334 rs1002412613	571	K>Q		No	ClinGen gnomAD
CA6408490 rs115935399	574	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs779392155 CA6408492	575	A>D		No	ClinGen ExAC gnomAD
rs757747939 CA6408491	575	A>T		No	ClinGen ExAC gnomAD
CA232389704 rs3180469	578	Q>*		No	ClinGen Ensembl
rs758935015 CA6408494	579	E>K		No	ClinGen ExAC TOPMed gnomAD
CA6408495 rs17725914 VAR_057511 RCV000965882	580	K>R		No	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA6408496 rs747140063	581	N>D		No	ClinGen ExAC gnomAD
rs1275222453 CA383578466	582	P>A		No	ClinGen TOPMed gnomAD
rs768670597 CA6408497	582	P>R		No	ClinGen ExAC gnomAD
CA383578476 rs776884151	583	R>G		No	ClinGen ExAC TOPMed gnomAD
rs145828257 CA6408499	583	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6408498 COSM942596 rs776884151	583	R>W	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA6408500 rs769642475	584	E>K		No	ClinGen ExAC gnomAD
rs1477372094 CA383578550	587	G>E		No	ClinGen gnomAD
CA6408504 rs774116129	589	M>I		No	ClinGen ExAC TOPMed gnomAD
CA383578584 rs151273606	589	M>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408503 rs151273606	589	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408502 rs762596170	589	M>V		No	ClinGen ExAC gnomAD
rs141590433 CA6408505	590	V>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1287489579 CA383578624	591	T>I		No	ClinGen gnomAD
rs1411003445 CA383578627	592	G>R		No	ClinGen gnomAD
CA383578656 rs1348647337	594	T>A		No	ClinGen gnomAD
rs752439922 CA6408507	594	T>I		No	ClinGen ExAC gnomAD
TCGA novel	595	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408509 rs765758094	595	V>I		No	ClinGen ExAC TOPMed gnomAD
CA383578672 rs765758094	595	V>L		No	ClinGen ExAC TOPMed gnomAD
CA383578697 rs1347191882	596	C>W		No	ClinGen TOPMed
rs750817353 CA6408510	597	K>I		No	ClinGen ExAC gnomAD
CA383578725 rs1217973438	598	N>H		No	ClinGen TOPMed gnomAD
rs200329416 CA6408511	598	N>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383578733 rs200329416	598	N>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs147032879 CA232389742	599	K>R		No	ClinGen ESP ExAC gnomAD
CA6408512 rs147032879	599	K>T		No	ClinGen ESP ExAC gnomAD
rs574601341 CA6408515	600	P>A		No	ClinGen ExAC TOPMed gnomAD
rs1450987147 CA383578765	600	P>R		No	ClinGen gnomAD
CA6408514 rs574601341	600	P>S		No	ClinGen ExAC TOPMed gnomAD
CA6408513 rs574601341	600	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1047913049 CA232389752	601	N>S		No	ClinGen TOPMed gnomAD
rs1186905733 CA383578802	602	M>I		No	ClinGen TOPMed
CA383578796 rs1187600833	602	M>T		No	ClinGen TOPMed gnomAD
CA383578793 rs1565545180 COSM1171933	602	M>V	oesophagus [Cosmic]	No	ClinGen cosmic curated Ensembl
TCGA novel	603	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777791363 CA6408518	604	D>N		No	ClinGen ExAC gnomAD
CA6408519 rs574753127	608	S>Y		No	ClinGen 1000Genomes ExAC gnomAD
rs148221378 CA6408520	609	R>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1378598766 CA383578874	613	E>*		No	ClinGen gnomAD
CA383578895 rs1192579986	616	K>R		No	ClinGen TOPMed
CA383578913 rs1396860805	618	E>D		No	ClinGen gnomAD
rs1433009894 CA383578921	619	M>I		No	ClinGen gnomAD
rs1306273345 CA383578957	625	Q>*		No	ClinGen TOPMed
CA383578963 rs1320066754	625	Q>H		No	ClinGen TOPMed gnomAD
rs1215543881 CA383578964	626	D>N		No	ClinGen TOPMed
CA383578972 rs1327283750	627	A>T		No	ClinGen gnomAD
CA6408522 rs759517573	627	A>V		No	ClinGen ExAC TOPMed gnomAD
CA6408523 rs369699402	628	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA383579004 rs935986083	631	S>C		No	ClinGen TOPMed gnomAD
CA232389764 rs935986083	631	S>F		No	ClinGen TOPMed gnomAD
rs745698478 CA6408526	632	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs778450010 CA6408525	632	R>W		No	ClinGen ExAC TOPMed gnomAD
CA232389770 rs913508713	633	K>N		No	ClinGen TOPMed
CA6408528 rs140245065	634	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs753378700 CA6408527	634	I>V		No	ClinGen ExAC gnomAD
rs1448390571 CA383579024	635	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs61751201 CA6408529	635	T>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1195747556 CA383579037	637	A>D		No	ClinGen gnomAD
CA6408531 rs755462892	638	I>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs752173146 CA6408530	638	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1053376976 CA232389780	639	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
TCGA novel	639	G>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs781620429 CA6408532	640	I>V		No	ClinGen ExAC TOPMed gnomAD
CA383579056 rs1455677887	641	I>V		No	ClinGen gnomAD
CA6408535 rs778079253	642	S>G		No	ClinGen ExAC gnomAD
rs369598953 CA232389789	642	S>N		No	ClinGen ESP TOPMed gnomAD
CA383579064 rs369598953	642	S>T		No	ClinGen ESP TOPMed gnomAD
CA383579089 rs1309692830	645	M>T		No	ClinGen TOPMed
TCGA novel	645	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6408562 rs780185175	652	V>A		No	ClinGen ExAC
CA6408537 rs770801928	652	V>M		No	ClinGen ExAC gnomAD
rs768272935 CA6408564	657	I>T		No	ClinGen ExAC gnomAD
CA383579199 COSM283131 rs1229509033	659	F>L	large_intestine Variant assessed as Somatic; impact. endometrium [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA383579254 rs1388159352	662	M>I		No	ClinGen gnomAD
rs1175244374 CA383579245	662	M>K		No	ClinGen TOPMed gnomAD
CA383579246 rs1175244374	662	M>T		No	ClinGen TOPMed gnomAD
rs776002331 CA6408565	662	M>V		No	ClinGen ExAC gnomAD
rs1461406372 CA383579267	663	V>A		No	ClinGen TOPMed gnomAD
rs1461406372 CA383579264	663	V>D		No	ClinGen TOPMed gnomAD
CA383579370 rs769346336	669	P>H		No	ClinGen ExAC TOPMed gnomAD
CA6408567 rs769346336	669	P>L		No	ClinGen ExAC TOPMed gnomAD
CA6408566 rs577139305	669	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs200624813 CA6408569	670	Q>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs767836400 CA6408570	672	L>M		No	ClinGen ExAC gnomAD
CA6408571 rs376195353	674	G>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408574 rs753865003	675	V>A		No	ClinGen ExAC gnomAD
CA6408573 rs764299547	675	V>L		No	ClinGen ExAC gnomAD
CA6408576 rs765575100	676	R>C	Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1329315235 CA383579471	676	R>H		No	ClinGen TOPMed
CA6408578 rs750628585	677	R>C		No	ClinGen ExAC gnomAD
rs148424921 CA6408579	677	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
COSM1258789 rs1172592484 CA383579506	678	M>I	oesophagus [Cosmic]	No	ClinGen cosmic curated TOPMed
CA6408580 rs779986183	678	M>L		No	ClinGen ExAC TOPMed gnomAD
CA232390095 rs779986183	678	M>V		No	ClinGen ExAC TOPMed gnomAD
rs142380498 CA383579519	680	P>A		No	ClinGen ESP TOPMed gnomAD
TCGA novel	680	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383579531 rs1427663937	680	P>L		No	ClinGen gnomAD
CA232390101 rs142380498	680	P>S		No	ClinGen ESP TOPMed gnomAD
CA6408583 rs781128388	684	S>Y		No	ClinGen ExAC gnomAD
CA383579656 rs1333124919	686	E>K		No	ClinGen gnomAD
rs1442483081 CA383579705	687	P>L		No	ClinGen gnomAD
rs769308867 CA6408585	687	P>T		No	ClinGen ExAC gnomAD
CA6408587 rs553615528	690	R>Q		No	ClinGen 1000Genomes ExAC gnomAD
rs1040000684 CA232390118	690	R>W		No	ClinGen TOPMed
CA232390122 rs893044825	691	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs978192011 CA232390125	692	A>P		No	ClinGen Ensembl
CA232390131 rs1041531227	693	V>G		No	ClinGen TOPMed
CA6408589 rs775825528	693	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1484223798 CA383579837	695	N>D		No	ClinGen TOPMed
rs761032094 CA6408590	695	N>S		No	ClinGen ExAC gnomAD
rs1484223798 CA383579838	695	N>Y		No	ClinGen TOPMed
rs1243333542 CA383579872	696	A>V		No	ClinGen gnomAD
CA383579906 COSM26986 rs1335484116	698	R>C	kidney large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
rs145931156 COSM1363694 CA6408591	698	R>H	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA6408593 rs777143284	699	Q>H		No	ClinGen ExAC gnomAD
CA6408594 rs765390473	701	Y>C		No	ClinGen ExAC gnomAD
CA6408595 rs765390473	701	Y>F		No	ClinGen ExAC gnomAD
CA383579994 rs1186861790	702	L>F		No	ClinGen TOPMed gnomAD
CA383580037 rs1303508754	704	P>S		No	ClinGen TOPMed
rs1222092568 CA383580059	705	K>*		No	ClinGen TOPMed
rs1054845746 CA232390141	705	K>R		No	ClinGen Ensembl
CA232390143 rs1003337409	706	G>R		No	ClinGen TOPMed
CA6408597 rs766643810	707	D>A		No	ClinGen ExAC gnomAD
rs772522759 CA6408596	707	D>Y		No	ClinGen ExAC gnomAD
rs1346018457 CA383581235	711	A>T		No	ClinGen gnomAD
rs1209858141 CA383581245	712	K>M		No	ClinGen gnomAD
rs1280827123 CA383581249	713	A>T		No	ClinGen gnomAD
rs756041204 CA6408620	713	A>V		No	ClinGen ExAC
rs777619239 CA6408621	714	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1480634348 CA383581329	719	N>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6408623 rs560391483	721	S>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383581371 rs560391483	721	S>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1321991801 CA383581363	721	S>P		No	ClinGen TOPMed
CA383581420 rs1436989464	725	V>A		No	ClinGen gnomAD
rs745498386 CA6408626	725	V>L		No	ClinGen ExAC gnomAD
CA383581412 rs745498386	725	V>M		No	ClinGen ExAC gnomAD
rs1327364886 CA383581453	726	D>E		No	ClinGen TOPMed gnomAD
rs768963981 CA6408627	727	A>G		No	ClinGen ExAC gnomAD
CA383581469 rs768963981	727	A>V		No	ClinGen ExAC gnomAD
rs781618742 CA6408628	728	S>L		No	ClinGen ExAC gnomAD
rs1592175584 CA383581499	729	V>G		No	ClinGen Ensembl
rs1369004404 CA383581511	730	G>E		No	ClinGen gnomAD
rs773808799 CA6408631	732	I>T		No	ClinGen ExAC gnomAD
CA383581566 rs1349711983	733	Q>H		No	ClinGen gnomAD
CA383581635 rs1212591201	738	I>T		No	ClinGen gnomAD
rs375366285 CA6408678	741	E>D		No	ClinGen ESP ExAC
CA6408677 rs745868065	741	E>V		No	ClinGen ExAC TOPMed gnomAD
rs1165777305 CA383583530	742	F>C		No	ClinGen gnomAD
TCGA novel	745	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763842161 CA6408681	746	D>V		No	ClinGen ExAC TOPMed gnomAD
CA6408682 rs761185581	747	E>*		No	ClinGen ExAC gnomAD
rs1432648448 CA383583741	751	A>S		No	ClinGen TOPMed gnomAD
rs1220542658 CA383583770	753	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs761738965 CA6408684	754	Q>H		No	ClinGen ExAC gnomAD
CA6408685 rs765021824	757	W>C		No	ClinGen ExAC
CA383583861 rs1195806624	757	W>R		No	ClinGen gnomAD
CA383583913 rs1348091995	758	E>D		No	ClinGen gnomAD
rs1565546352 CA383583891	758	E>Q		No	ClinGen Ensembl
CA6408687 rs575891537	759	R>Q		No	ClinGen 1000Genomes ExAC gnomAD
rs749966496 CA6408686	759	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	760	A>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1360469939 CA383584035	762	E>G		No	ClinGen TOPMed gnomAD
COSM162816 rs61763002 CA6408689	762	E>K	oesophagus breast [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA232392402 rs61763002	762	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA383584089 rs1592176748	764	V>G		No	ClinGen Ensembl
rs778270049 CA6408691	765	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1188744102 CA383584134	766	C>R		No	ClinGen gnomAD
CA383584176 rs749876235	767	C>R		No	ClinGen ExAC TOPMed gnomAD
rs749876235 CA6408692	767	C>S		No	ClinGen ExAC TOPMed gnomAD
CA232392425 rs972819783	768	P>A		No	ClinGen gnomAD
CA383584199 rs972819783	768	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA383584257 rs1402183922	771	R>C		No	ClinGen gnomAD
CA383584262 rs1310900245	771	R>H		No	ClinGen TOPMed gnomAD
rs1310900245 CA383584265	771	R>L		No	ClinGen TOPMed gnomAD
CA383584276 rs779228154	772	C>R		No	ClinGen ExAC gnomAD
CA6408694 rs779228154	772	C>S		No	ClinGen ExAC gnomAD
CA6408695 rs745980585	774	S>P		No	ClinGen ExAC gnomAD
CA383584356 rs1164972734	776	M>I		No	ClinGen TOPMed
rs1413443276 CA383584345	776	M>K		No	ClinGen gnomAD
TCGA novel	776	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772001628 CA6408696	778	L>F		No	ClinGen ExAC gnomAD
CA383584396 rs1427232816	779	G>D		No	ClinGen TOPMed
rs1279729513 CA383584407	780	M>L		No	ClinGen gnomAD
CA383584436 rs1341506892	781	M>K		No	ClinGen TOPMed gnomAD
CA383584432 rs1341506892	781	M>T		No	ClinGen TOPMed gnomAD
rs1000859870 COSM1676664 CA232392456	783	R>*	ovary [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs1242738698 CA383584469	783	R>Q		No	ClinGen gnomAD
CA6408721 rs773253189	787	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA6408722 rs555328861	787	E>V		No	ClinGen ExAC TOPMed gnomAD
rs1461455282 CA383584654	790	G>R		No	ClinGen gnomAD
rs1167978105 CA383584693	792	N>S		No	ClinGen gnomAD
rs1427039429 CA383584697	793	L>V		No	ClinGen TOPMed gnomAD
CA6408723 rs539898238	795	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs774002338 CA6408724	796	L>V		No	ClinGen ExAC gnomAD
VAR_024422 rs10849482 CA6408725	797	V>M		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA6408726 rs767298691	798	S>N		No	ClinGen ExAC gnomAD
CA6408727 rs752250325	799	I>T		No	ClinGen ExAC gnomAD
CA383584739 rs1303919612	800	G>R		No	ClinGen gnomAD
rs1300581509 CA383584748	801	L>P		No	ClinGen gnomAD
rs1304996535 CA383584762	803	E>G		No	ClinGen TOPMed
TCGA novel	803	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383584796 rs1320004931	808	D>N		No	ClinGen gnomAD
CA6408731 CA6408732 rs560070593	810	R>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383584815 rs1211933217	810	R>T		No	ClinGen gnomAD
rs76687187 CA6408733	812	A>G		No	ClinGen 1000Genomes ExAC gnomAD
rs76687187 CA232392657	812	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1592176989 CA383584829	813	Q>P		No	ClinGen Ensembl
CA383584869 rs1592176994	815	V>G		No	ClinGen Ensembl
rs1399955129 CA383584901	817	H>L		No	ClinGen gnomAD
CA6408734 rs572247056	819	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs781436926 CA6408735	820	A>V		No	ClinGen ExAC gnomAD
rs748297703 CA6408736	821	N>D		No	ClinGen ExAC gnomAD
CA6408737 rs755997061	821	N>S		No	ClinGen ExAC TOPMed gnomAD
rs777426754 CA6408738	822	I>V		No	ClinGen ExAC gnomAD
rs369160973 CA6408739	823	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs369160973 CA383584997	823	S>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs774381395 CA6408741	826	R>G		No	ClinGen ExAC TOPMed gnomAD
rs1044265729 CA232392666	827	K>R		No	ClinGen TOPMed gnomAD
CA383585115 rs1240568500	828	P>L		No	ClinGen gnomAD
rs1316607660 CA383585108	828	P>S		No	ClinGen gnomAD
rs771761429 CA6408761	829	S>F		No	ClinGen ExAC gnomAD
CA6408762 rs562898088	830	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs746458872 CA6408763	832	K>R		No	ClinGen ExAC gnomAD
CA383585162 rs1258140496	833	R>C		No	ClinGen TOPMed gnomAD
rs768218178 CA6408764	833	R>H		No	ClinGen ExAC gnomAD
rs1592177116 CA383585178	834	H>P		No	ClinGen Ensembl
CA383585202 rs1290527575	835	P>R		No	ClinGen Ensembl
CA232392781 rs1018414996	835	P>S		No	ClinGen TOPMed gnomAD
CA6408768 rs201468201	836	P>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs73259178 CA6408773	836	P>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs73259178 CA6408771	836	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs73259178 CA6408772	836	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201468201 CA6408770	836	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201468201 CA6408769	836	P>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs764251363 CA6408776	837	F>C		No	ClinGen ExAC gnomAD
rs772347389	837	F>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs772347389	837	F>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA383585232 rs527891354	838	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM141366 rs778834087 CA6408779	838	R>Q	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs527891354 CA6408778	838	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383585241 rs1592177143	839	L>V		No	ClinGen Ensembl
rs769382114 CA6408780	840	P>R		No	ClinGen ExAC TOPMed gnomAD
CA232392819 rs957172228	840	P>T		No	ClinGen Ensembl
CA6408782 rs375096381	842	E>D		No	ClinGen ExAC TOPMed gnomAD
rs562323013 CA6408781	842	E>K		No	ClinGen ExAC TOPMed gnomAD
CA383585330 rs1311761425	844	R>G		No	ClinGen TOPMed gnomAD
rs746535565 CA6408783	845	L>F		No	ClinGen ExAC gnomAD
CA383585377 rs1233326398	846	F>S		No	ClinGen gnomAD
CA232392825 rs139932236	848	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA TOPMed
CA6408785 rs780760183	848	R>Q		No	ClinGen ExAC gnomAD
rs771352876 CA6408787	850	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs200921592 CA6408786	850	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6408788 rs774704688	851	E>Q		No	ClinGen ExAC gnomAD
rs1296467038 CA383585513	853	V>I		No	ClinGen TOPMed
CA6408790 rs772478532	854	T>K		No	ClinGen ExAC gnomAD
CA383585733 rs1480614824	858	V>G		No	ClinGen TOPMed
rs113663520 CA232392928	859	H>R		No	ClinGen Ensembl
CA383585737 rs1565546701	859	H>Y		No	ClinGen Ensembl
CA383585772 rs1270862633	860	P>A		No	ClinGen gnomAD
rs1252381422 CA383585806	861	D>E		No	ClinGen TOPMed
CA383585897 rs753674713	864	W>*		No	ClinGen TOPMed gnomAD
CA383585900 CA232392943 rs753674713	864	W>C		No	ClinGen TOPMed gnomAD
CA383585925 rs1282967115	865	I>M		No	ClinGen TOPMed
rs1321850665 CA383585916	865	I>N		No	ClinGen TOPMed
rs746261413 CA6408807	866	P>T		No	ClinGen ExAC gnomAD
CA6408808 rs772449545	868	K>R		No	ClinGen ExAC TOPMed gnomAD
rs927128257 CA232392964	870	V>M		No	ClinGen Ensembl
rs1419459612 CA383586070	872	V>G		No	ClinGen gnomAD
CA6408809 rs775910125	872	V>M		No	ClinGen ExAC gnomAD
TCGA novel	873	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs941238695 CA232392971	874	L>F		No	ClinGen Ensembl
CA383586167 rs1333002063	877	Q>*		No	ClinGen TOPMed
CA232392982 rs918535347	881	G>S		No	ClinGen TOPMed
CA6408814 rs373969636	882	P>L		No	ClinGen ESP ExAC gnomAD
rs761924426 CA6408813	882	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1405098549 CA383586360	885	I>M		No	ClinGen TOPMed
rs1468103619 CA383586355	885	I>T		No	ClinGen TOPMed
CA6408817 rs376684532	886	C>G		No	ClinGen ESP ExAC gnomAD
rs754947508 CA6408819	891	Q>E		No	ClinGen ExAC TOPMed gnomAD
COSM1492987 rs149823221 CA6408821	893	C>S	kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs149823221 CA383586544	893	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408823 rs529714238	895	K>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs760940470 CA6408825	897	A>P		No	ClinGen ExAC gnomAD
rs760940470 CA232393023	897	A>T		No	ClinGen ExAC gnomAD
rs780458107 CA6408826	898	L>P		No	ClinGen ExAC gnomAD
CA232393040 rs891101793	899	E>G		No	ClinGen Ensembl
rs567934148 CA232393064	900	K>N		No	ClinGen Ensembl
rs549446525 CA6408829	900	K>R		No	ClinGen 1000Genomes ExAC gnomAD
rs549446525 CA6408828	900	K>T		No	ClinGen 1000Genomes ExAC gnomAD
CA232393065 rs942789281	902	E>G		No	ClinGen TOPMed
rs1460329218 CA383586772	904	K>E		No	ClinGen TOPMed
CA6408831 rs769975634	905	R>T		No	ClinGen ExAC gnomAD
CA232393068 rs773631088	906	T>N		No	ClinGen ExAC TOPMed gnomAD
rs773631088 CA6408832	906	T>S		No	ClinGen ExAC TOPMed gnomAD
CA383586823 rs1259167593	907	S>R		No	ClinGen TOPMed
rs145781104 CA6408833	911	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs145781104 CA232393070	911	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA6408852 rs141629311	914	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA383587064 rs1565546880	915	P>L		No	ClinGen Ensembl
rs1344973671 CA383587082	916	A>G		No	ClinGen gnomAD
rs759414047 CA6408854	916	A>T		No	ClinGen ExAC gnomAD
TCGA novel	917	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1324892313 CA383587094	917	M>V		No	ClinGen TOPMed
CA383587138 rs1164604207	919	P>L		No	ClinGen TOPMed gnomAD
CA232393174 rs1029968725	919	P>T		No	ClinGen TOPMed
rs752579769 CA232393178	920	T>N		No	ClinGen Ensembl
rs1280900191 CA383587145	920	T>P		No	ClinGen gnomAD
rs771829488 CA6408855	921	F>L		No	ClinGen ExAC gnomAD
CA383587173 rs1392784516	921	F>S		No	ClinGen gnomAD
CA6408856 rs375952478	922	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1478344737 CA383587187	922	L>P		No	ClinGen TOPMed
rs953080684 CA232393192	924	M>T		No	ClinGen TOPMed gnomAD
rs1191562471 CA383587248	925	N>S		No	ClinGen gnomAD
rs1191562471 CA383587246	925	N>T		No	ClinGen gnomAD
CA383587304 rs1247389265	928	S>F		No	ClinGen TOPMed
CA6408859 rs753399311	930	A>P		No	ClinGen ExAC gnomAD
rs761176052 CA6408860	930	A>V		No	ClinGen ExAC gnomAD
rs764970826 CA6408861	934	A>T		No	ClinGen ExAC gnomAD
CA383587461 rs1592177514	939	V>G		No	ClinGen Ensembl
rs781689943 CA6408864	943	Q>L		No	ClinGen ExAC gnomAD
rs753048861 CA6408865	944	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1337489294 CA383587567	945	V>A		No	ClinGen gnomAD
rs1198119934 CA383587594	946	S>R		No	ClinGen gnomAD
rs1260954230 CA383587598	947	G>R		No	ClinGen TOPMed
CA6408867 rs778093338	948	E>D		No	ClinGen ExAC TOPMed gnomAD
CA383587701 rs1440200876	950	C>W		No	ClinGen TOPMed gnomAD
rs759714048 CA6408870	951	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs145370494 CA6408869	951	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs746074962 CA6408872 RCV000994830 COSM4147397	952	R>C	thyroid [Cosmic]	No	ClinGen cosmic curated ClinVar ExAC TOPMed dbSNP gnomAD
CA6408873 rs373602126	952	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs775267429 CA6408874	953	R>*		No	ClinGen ExAC gnomAD
rs949516994 CA232393273	953	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA6408876 rs768599305	954	V>A		No	ClinGen ExAC gnomAD
CA6408875 rs753785916	954	V>I		No	ClinGen ExAC gnomAD
rs764641749 CA6408879	956	R>Q		No	ClinGen ExAC TOPMed gnomAD
COSM333235 rs147656435 CA6408878	956	R>W	lung [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA6408880 rs750160826	961	H>R		No	ClinGen ExAC TOPMed gnomAD
CA232393292 rs942600606	962	K>E		No	ClinGen TOPMed gnomAD
rs527945485 CA6408882	963	T>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383588062 rs1458993556	964	K>E		No	ClinGen TOPMed
CA383588073 rs1320252246	964	K>R		No	ClinGen gnomAD
CA383588111 rs1231619080	965	D>G		No	ClinGen gnomAD
rs1265087537 CA383588126	966	P>A		No	ClinGen gnomAD
rs368743000 CA6408883	967	K>Q		No	ClinGen 1000Genomes ExAC gnomAD
rs750520878 CA6408907	971	T>M		No	ClinGen ExAC TOPMed gnomAD
rs750520878 CA383589682	971	T>R		No	ClinGen ExAC TOPMed gnomAD
rs141891272 CA6408910	973	S>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs754870926 CA6408911	974	E>D		No	ClinGen ExAC TOPMed gnomAD
CA232393655 rs867015735	974	E>K		No	ClinGen Ensembl
rs552225344 CA6408912	975	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs747923932 CA6408913	976	T>A		No	ClinGen ExAC TOPMed gnomAD
rs970819686 CA232393664	976	T>I		No	ClinGen gnomAD
rs1396627617 CA603484172	977	M>*		No	ClinGen TOPMed
CA6408915 rs559117736	977	M>I		No	ClinGen 1000Genomes ExAC gnomAD
CA383589791 rs1565547198	977	M>T		No	ClinGen Ensembl
CA383589781 rs1359858675	977	M>V		No	ClinGen TOPMed gnomAD
rs774202915 CA6408919	984	V>A		No	ClinGen ExAC gnomAD
CA6408918 rs770545116	984	V>L		No	ClinGen ExAC gnomAD
rs1166904134 CA383589997	986	A>T		No	ClinGen TOPMed
rs1419668971 CA383590071	989	D>E		No	ClinGen TOPMed
rs767129732 CA6408921	990	D>N		No	ClinGen ExAC gnomAD
CA383590104 rs1188379934	991	T>S		No	ClinGen TOPMed
CA6408922 rs776872395	992	E>G		No	ClinGen ExAC gnomAD
rs1413324059 CA383590118	992	E>Q		No	ClinGen gnomAD
CA232393704 rs926784989	994	E>K		No	ClinGen Ensembl
rs765761412 CA6408924	996	I>M		No	ClinGen ExAC TOPMed gnomAD
rs750894814 CA6408925 COSM942599	997	R>C	endometrium [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA6408926 rs758518981	997	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6408927 rs766445226	998	G>A		No	ClinGen ExAC gnomAD
CA6408928 rs751574432	999	I>M		No	ClinGen ExAC gnomAD
CA383590289 rs1365394456	1000	C>F		No	ClinGen gnomAD
rs781430629 CA6408930	1001	E>K		No	ClinGen ExAC gnomAD
rs1196234958 CA383590376	1003	E>Q		No	ClinGen gnomAD
CA6408931 rs747927145	1004	L>M		No	ClinGen ExAC gnomAD
rs747927145 CA6408932	1004	L>V		No	ClinGen ExAC gnomAD
CA6408935 rs770630836	1005	L>S		No	ClinGen ExAC TOPMed gnomAD
CA232393727 rs973592259	1006	D>N		No	ClinGen Ensembl
rs867422941 CA232393772	1007	G>D		No	ClinGen Ensembl
rs1477246743 CA383590461	1007	G>R		No	ClinGen gnomAD
rs1477246743 CA383590458	1007	G>S		No	ClinGen gnomAD
CA383590551 rs1441390548	1008	K>E		No	ClinGen TOPMed gnomAD
CA383590548 rs1441390548	1008	K>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1277094533 CA383590558	1008	K>R		No	ClinGen TOPMed gnomAD
rs770118614 CA6408944	1010	T>R		No	ClinGen ExAC TOPMed gnomAD
CA6408945 rs773763595	1014	F>L		No	ClinGen ExAC gnomAD
rs763458491 CA6408946	1014	F>S		No	ClinGen ExAC gnomAD
CA383590722 rs1592178028	1016	P>L		No	ClinGen Ensembl
rs1592178025 CA383590716	1016	P>S		No	ClinGen Ensembl
rs766817718 CA6408947	1017	L>V		No	ClinGen ExAC gnomAD
CA6408948 rs751617976	1018	L>F		No	ClinGen ExAC gnomAD
CA383590757 rs1210785759	1018	L>S		No	ClinGen TOPMed gnomAD
rs1040808363 CA232393808	1023	N>D		No	ClinGen Ensembl
CA383590906 rs1491001809	1023	N>I		No	ClinGen gnomAD
CA232393815 rs899580035	1027	L>F		No	ClinGen gnomAD
rs1478194264 CA383591001	1027	L>R		No	ClinGen gnomAD
CA690985766 rs1232298598	1028	Y>*		No	ClinGen TOPMed
CA383591006 rs1592178046	1028	Y>C		No	ClinGen Ensembl
rs936195223 CA232393819	1029	S>R		No	ClinGen TOPMed
rs148269816 CA6408951	1031	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1253830994 CA383591087	1032	D>G		No	ClinGen TOPMed
CA6408952 rs755921917	1032	D>N		No	ClinGen ExAC gnomAD
rs1351543825 CA383591229	1037	A>P		No	ClinGen TOPMed gnomAD
CA6408954 rs753618516	1039	L>R		No	ClinGen ExAC gnomAD
CA6408955 rs757270086	1040	A>V		No	ClinGen ExAC gnomAD
CA232393844 rs112784312	1042	G>S		No	ClinGen Ensembl
TCGA novel	1043	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771579024 CA6408958	1045	C>*		No	ClinGen ExAC gnomAD
CA6408957 rs745400484	1045	C>R		No	ClinGen ExAC gnomAD
rs1355253961 CA383591446	1045	C>Y		No	ClinGen gnomAD
rs1291107687 CA383591562	1048	S>R		No	ClinGen gnomAD
rs529956181 CA232393895	1049	A>V		No	ClinGen Ensembl
CA232393900 rs1020969156	1050	T>I		No	ClinGen Ensembl
rs1565547372 CA383591741	1051	F>Y		No	ClinGen Ensembl
rs1385392397 CA383591812	1053	D>G		No	ClinGen gnomAD
rs779610078 CA6408976	1053	D>N		No	ClinGen ExAC TOPMed gnomAD
rs1042057335 CA383591864	1054	S>F		No	ClinGen TOPMed gnomAD
rs1042057335 CA232393920	1054	S>Y		No	ClinGen TOPMed gnomAD
CA6408978 rs754648578	1057	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs780783630 CA6408979	1057	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6408980 rs749693715	1060	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1395790061 CA383592007	1060	F>S		No	ClinGen TOPMed
CA383592044 rs1441931164	1062	M>V		No	ClinGen gnomAD
rs140333484 CA232393969	1063	L>V		No	ClinGen ESP TOPMed gnomAD
CA6408981 rs771267179	1064	E>G		No	ClinGen ExAC TOPMed gnomAD
rs1244117357 CA383592090	1064	E>K		No	ClinGen TOPMed
CA232393976 rs376901782	1065	K>E		No	ClinGen Ensembl
rs150344215 CA383592147	1065	K>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA383592132 rs1437564196	1065	K>R		No	ClinGen TOPMed gnomAD
CA383592182 rs1380833439	1067	P>L		No	ClinGen TOPMed gnomAD
TCGA novel	1067	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746385360 CA6408983	1068	L>F		No	ClinGen ExAC TOPMed gnomAD
rs746385360 CA232393980	1068	L>I		No	ClinGen ExAC TOPMed gnomAD
rs772391132 CA232393986	1069	P>H		No	ClinGen ExAC gnomAD
CA6408984 rs772391132	1069	P>R		No	ClinGen ExAC gnomAD
CA383592194 rs1303510000	1069	P>T		No	ClinGen TOPMed
CA6408985 rs566534807	1070	I>M		No	ClinGen ExAC gnomAD
rs1414578905 CA383592225	1071	V>I		No	ClinGen gnomAD
rs760783711 CA6408986	1072	R>G		No	ClinGen ExAC gnomAD
CA6408987 rs764438216	1072	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs760783711 CA383592251	1072	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1365034772 CA383592275	1073	S>A		No	ClinGen TOPMed
CA6408989 rs776962591	1074	N>T		No	ClinGen ExAC gnomAD
rs1378279199 CA383592329	1075	L>F		No	ClinGen TOPMed gnomAD
CA232394009 rs974005511	1075	L>H		No	ClinGen Ensembl
rs920743401 CA232394010	1076	M>I		No	ClinGen gnomAD
rs761748740 CA6408990	1076	M>K		No	ClinGen ExAC gnomAD
rs929564192 CA232394011	1077	V>A		No	ClinGen TOPMed
CA6408991 rs765067047	1078	A>V		No	ClinGen ExAC gnomAD
rs1201155682 CA383592398	1080	G>R		No	ClinGen gnomAD
rs763728649 CA6408992	1081	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs137946874 CA6408993	1081	D>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs766180121 CA6408994	1083	A>T		No	ClinGen ExAC gnomAD
rs751101647 CA6408995	1083	A>V		No	ClinGen ExAC
CA383592461 rs1420655691	1084	I>V		No	ClinGen gnomAD
rs199911941 CA6408996	1085	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs780875665 CA6408997	1085	R>H		No	ClinGen ExAC TOPMed gnomAD
rs747789607 CA6408998	1087	P>A		No	ClinGen ExAC gnomAD
rs757688351 CA6408999	1088	N>S		No	ClinGen ExAC gnomAD
CA383592550 rs1421019529	1089	L>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA232394029 rs955405147	1092	P>H		No	ClinGen TOPMed
rs1040672241 CA232394025	1092	P>T		No	ClinGen Ensembl
rs1187363713 CA383592682	1094	T>A		No	ClinGen TOPMed
TCGA novel	1095	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768833927 CA6409006	1100	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6409007 rs145942484	1100	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA383592902 rs145942484	1100	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409036 rs201735986	1102	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs760060496 CA6409035	1102	R>W		No	ClinGen ExAC TOPMed gnomAD
rs927733594 CA232394214	1104	P>S		No	ClinGen TOPMed
CA232394215 rs1003430222	1108	V>A		No	ClinGen TOPMed gnomAD
rs758855845 CA383593248	1109	R>G		No	ClinGen ExAC TOPMed gnomAD
CA6409039 rs377720436	1109	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409038 rs758855845	1109	R>W		No	ClinGen ExAC TOPMed gnomAD
CA383593279 rs1364339867	1111	T>I		No	ClinGen TOPMed gnomAD
CA383593276 rs1364339867	1111	T>K		No	ClinGen TOPMed gnomAD
CA6409041 rs751904500	1112	A>G		No	ClinGen ExAC TOPMed gnomAD
CA6409040 rs751904500	1112	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA232394264 rs995240821	1113	G>E		No	ClinGen Ensembl
CA6409045 rs778115986	1114	L>V		No	ClinGen ExAC gnomAD
rs144412706 CA6409046	1116	M>T		No	ClinGen ESP ExAC gnomAD
CA6409047 rs771079029	1118	H>L		No	ClinGen ExAC gnomAD
TCGA novel	1120	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6409049 rs759275805	1122	K>N		No	ClinGen ExAC TOPMed gnomAD
rs1592178411 CA383593516	1124	M>T		No	ClinGen Ensembl
rs1256445771 CA383593591	1128	K>T		No	ClinGen gnomAD
CA6409051 rs775371502	1130	Q>*		No	ClinGen ExAC
rs760278075 CA6409052	1131	V>F		No	ClinGen ExAC gnomAD
rs1592178427 CA383593669	1131	V>G		No	ClinGen Ensembl
CA6409054 rs753592881	1133	E>K		No	ClinGen ExAC TOPMed gnomAD
rs761374345 CA6409055	1134	M>T		No	ClinGen ExAC TOPMed gnomAD
CA6409056 rs764924444	1135	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1592178439 CA383593790	1136	V>G		No	ClinGen Ensembl
CA6409058 rs755365795	1136	V>M		No	ClinGen ExAC gnomAD
CA383593805 rs1407161636	1137	L>Q		No	ClinGen gnomAD
CA383593863 rs1262181768	1140	D>A		No	ClinGen TOPMed
CA383593866 rs1262181768	1140	D>G		No	ClinGen TOPMed
rs756287772 CA6409061	1140	D>N		No	ClinGen ExAC TOPMed gnomAD
CA6409062 rs777724116	1142	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1309094201 CA383593944	1143	P>L		No	ClinGen gnomAD
CA232394413 rs966285425	1147	A>P		No	ClinGen TOPMed
rs966285425 CA383594001	1147	A>S		No	ClinGen TOPMed
CA6409065 rs779063654	1150	K>N		No	ClinGen ExAC TOPMed gnomAD
CA383594046 rs1236673034	1151	N>S		No	ClinGen gnomAD
RCV000761816 rs1592178488	1153	F>missing		No	ClinVar dbSNP
CA6409067 rs199672478	1154	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs775551952 CA6409068	1156	L>F		No	ClinGen ExAC gnomAD
CA383594094 rs1431479013	1158	H>Y		No	ClinGen gnomAD
CA6409083 rs757293887	1160	G>S		No	ClinGen ExAC gnomAD
rs740850 CA383594133	1161	N>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs746072942 CA6409085	1162	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA232394615 rs376852566	1163	I>T		No	ClinGen Ensembl
rs1042256199 CA232394608	1163	I>V		No	ClinGen TOPMed
rs35819349 CA6409087	1165	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1020979197 CA383594189	1166	L>F		No	ClinGen TOPMed gnomAD
TCGA novel	1166	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768498216 CA6409089	1166	L>R		No	ClinGen ExAC gnomAD
CA232394659 rs1020979197	1166	L>V		No	ClinGen TOPMed gnomAD
rs139998720 CA6409090	1167	L>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs145398040 CA6409092	1170	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
RCV000952977 CA6409093 rs71579325	1170	I>T		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA383594236 rs145398040	1170	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs766002564 CA6409095 COSM942600	1173	R>C	Variant assessed as Somatic; 0.0 impact. urinary_tract endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs183788505 CA6409097	1173	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs183788505 CA6409096	1173	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs754345866 CA6409099	1178	E>K		No	ClinGen ExAC TOPMed gnomAD
CA6409100 rs761935164	1179	L>R		No	ClinGen ExAC gnomAD
rs1472426192 CA383594354 CA383594356	1180	G>R		No	ClinGen TOPMed
CA6409101 rs765293144	1181	V>M		No	ClinGen ExAC gnomAD
rs1438505109 CA383594457	1186	F>L		No	ClinGen TOPMed
CA6409102 rs149767105	1187	H>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs758632306 CA6409103	1187	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA383594503 rs1565547811	1188	T>I		No	ClinGen Ensembl
CA383594510 rs751341613	1189	I>F		No	ClinGen ExAC TOPMed gnomAD
CA6409105 rs751341613	1189	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1228177349 CA383594526	1190	M>V		No	ClinGen TOPMed
TCGA novel	1192	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383596264 rs1351431978	1197	I>T		No	ClinGen TOPMed gnomAD
rs1163329000 CA383596258	1197	I>V		No	ClinGen TOPMed
CA6409129 rs200410385	1200	D>G		No	ClinGen 1000Genomes ExAC TOPMed
rs367671840 CA232395141	1200	D>N		No	ClinGen Ensembl
CA383596320 rs1461093595	1201	K>E		No	ClinGen gnomAD
CA6409131 rs777815289	1203	T>R		No	ClinGen ExAC TOPMed gnomAD
rs1244672459 CA383596380	1204	E>D		No	ClinGen gnomAD
CA6409132 rs748850248	1205	S>N		No	ClinGen ExAC gnomAD
rs940733540 CA232395162	1205	S>R		No	ClinGen Ensembl
CA383596404 rs748850248	1205	S>T		No	ClinGen ExAC gnomAD
rs963896703 CA232395177	1210	L>V		No	ClinGen TOPMed gnomAD
rs1040333456 CA232395184	1212	Q>*		No	ClinGen gnomAD
rs373223388 CA6409134	1212	Q>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409133 rs373223388	1212	Q>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA232395202 rs932030786	1213	R>Q		No	ClinGen gnomAD
CA383596592 rs1469946630	1213	R>W		No	ClinGen gnomAD
rs555494125 CA6409135	1215	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383596623 rs555494125	1215	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs771553945 CA6409136	1215	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6409137 rs575359551	1216	T>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1231776815 CA383596664	1218	R>*		No	ClinGen gnomAD
CA6409138 RCV000965883 rs61731148	1218	R>L		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA383596668 rs61731148	1218	R>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6409139 rs61731148	1218	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA232395418 rs370458466	1221	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409161 rs199575493	1221	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409160 rs370458466	1221	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA232395441 rs1019200749	1222	Q>R		No	ClinGen TOPMed
rs749807940 CA6409162	1223	Q>R		No	ClinGen ExAC gnomAD
rs1193474325 CA383596809	1224	R>*		No	ClinGen TOPMed gnomAD
CA383596807 rs1193474325	1224	R>G		No	ClinGen TOPMed gnomAD
rs1373953332 CA383596812	1224	R>Q		No	ClinGen gnomAD
rs1463871817 CA383596819	1225	D>N		No	ClinGen gnomAD
rs1162197971 CA383596830	1225	D>V		No	ClinGen gnomAD
rs774515068 CA6409164	1228	Y>S		No	ClinGen ExAC gnomAD
rs759496497 CA6409165	1229	C>R		No	ClinGen ExAC gnomAD
rs1382896370 CA383596883	1229	C>Y		No	ClinGen gnomAD
CA6409166 rs767896125	1232	Q>*		No	ClinGen ExAC gnomAD
rs1201170710 CA383596933	1235	L>F		No	ClinGen TOPMed
rs950114293 CA232395486	1235	L>R		No	ClinGen gnomAD
CA383596951 rs1242408234	1238	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs760601566 CA6409168	1238	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs753507430 CA383596960	1240	L>F		No	ClinGen ExAC TOPMed gnomAD
rs568168937 CA6409171	1240	L>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs753507430 CA6409170	1240	L>V		No	ClinGen ExAC TOPMed gnomAD
CA383596975 rs1485276238	1241	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs145700246 CA6409172	1241	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs145700246 CA383596978	1241	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383596995 rs1396158551	1243	M>T		No	ClinGen TOPMed
CA232395495 rs963949265	1244	L>F		No	ClinGen TOPMed
rs1300746470 CA383597002	1244	L>P		No	ClinGen TOPMed
rs757872384 CA6409174	1248	D>E		No	ClinGen ExAC gnomAD
CA383597051 rs1424083804	1251	G>R		No	ClinGen TOPMed
CA6409176 rs746660180	1253	K>I		No	ClinGen ExAC gnomAD
CA383597069 rs746660180	1253	K>R		No	ClinGen ExAC gnomAD
rs896106461 CA232395520	1257	E>V		No	ClinGen Ensembl
rs143558583 CA232395532	1258	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs143558583 CA6409177 COSM124685	1258	S>Y	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA6409179 rs749568050	1259	I>T		No	ClinGen ExAC gnomAD
rs367748817 CA6409178	1259	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA383597113 rs1453177336	1260	F>S		No	ClinGen gnomAD
rs550917748 CA6409181	1261	S>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1261	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs571079372 CA6409182	1262	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6409183 rs540155011	1264	L>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs540155011 CA6409184	1264	L>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs760978668 CA6409185	1265	S>A		No	ClinGen ExAC gnomAD
rs768938249 CA6409186	1266	V>F		No	ClinGen ExAC TOPMed gnomAD
rs137981914 CA6409188	1267	V>G		No	ClinGen ExAC gnomAD
CA6409187 rs117693002	1267	V>L		No	ClinGen 1000Genomes ExAC gnomAD
rs1262119428 CA383597161	1268	G>D		No	ClinGen gnomAD
CA6409191 rs762518201	1271	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs765878757 CA6409192	1272	R>C		No	ClinGen ExAC gnomAD
CA232395645 rs778637362	1272	R>H		No	ClinGen TOPMed gnomAD
rs751014766 CA6409193	1273	G>E		No	ClinGen ExAC gnomAD
TCGA novel	1274	A>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383597195 rs1310060656	1274	A>V		No	ClinGen TOPMed
CA6409194 rs754648653	1275	K>E		No	ClinGen ExAC gnomAD
CA6409195 rs780672076	1275	K>T		No	ClinGen ExAC gnomAD
CA383597206 rs1468379650	1276	P>R		No	ClinGen gnomAD
rs1403853695 CA383597317	1281	I>L		No	ClinGen TOPMed gnomAD
rs1283492437 CA383597330	1281	I>M		No	ClinGen TOPMed gnomAD
rs1403853695 CA383597320	1281	I>V		No	ClinGen TOPMed gnomAD
CA383597349 rs779146378	1282	I>R		No	ClinGen ExAC TOPMed gnomAD
CA6409215 rs779146378	1282	I>T		No	ClinGen ExAC TOPMed gnomAD
CA383597335 rs1347078774	1282	I>V		No	ClinGen gnomAD
CA383597407 rs1565548507	1286	E>K		No	ClinGen Ensembl
rs1268944323 CA383597540	1289	L>F		No	ClinGen gnomAD
CA232396054 rs368324917	1290	R>Q		No	ClinGen ESP TOPMed gnomAD
CA383597557 rs1307291517 COSM1363702	1290	R>W	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
TCGA novel	1291	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA383597597 rs1489870291	1292	C>R		No	ClinGen gnomAD
rs201167890 CA6409217	1293	H>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA383597707 rs780665574	1296	G>D		No	ClinGen ExAC gnomAD
rs780665574 CA6409218	1296	G>V		No	ClinGen ExAC gnomAD
rs920568435 CA232396058	1299	G>R		No	ClinGen TOPMed gnomAD
rs887404872 CA232396063	1301	K>E		No	ClinGen TOPMed gnomAD
CA383597831 rs1428920182	1303	L>V		No	ClinGen gnomAD
rs1268504593 CA383597855	1304	E>G		No	ClinGen Ensembl
CA6409219 rs185696673	1306	G>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6409220 rs768596090	1308	A>T		No	ClinGen ExAC TOPMed gnomAD
CA383597942 rs1423450108	1309	G>V		No	ClinGen gnomAD
rs983699259 CA232396078	1311	Q>*		No	ClinGen TOPMed
CA383597980 rs1565548532	1311	Q>L		No	ClinGen Ensembl
CA383598001 rs1303293740	1312	R>K		No	ClinGen gnomAD
CA6409221 rs563085688	1312	R>S		No	ClinGen ExAC gnomAD
rs1387754035 CA383598010	1313	A>T		No	ClinGen TOPMed
CA383598046 rs1592179708	1315	S>P		No	ClinGen Ensembl
CA6409224 rs772906249	1316	A>D		No	ClinGen ExAC TOPMed gnomAD
CA6409225 rs749043373	1318	K>N		No	ClinGen ExAC gnomAD
CA383598120 rs1298349531	1319	P>A		No	ClinGen TOPMed
CA383598135 rs1357995135	1320	S>A		No	ClinGen gnomAD
rs770899017 CA6409227	1321	T>A		No	ClinGen ExAC gnomAD
VAR_058713 rs2240871 CA6409228	1321	T>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA6409230 rs200487459	1322	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs867468677 CA232396212	1322	G>V		No	ClinGen Ensembl
CA232396213 rs375102795	1325	Y>*		No	ClinGen ESP TOPMed
CA383598286 rs757407957	1325	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA6409262 rs757407957	1325	Y>S		No	ClinGen ExAC TOPMed gnomAD
CA6409264 rs745623301	1327	P>L		No	ClinGen ExAC gnomAD
rs771931892 CA6409265	1329	A>V		No	ClinGen ExAC gnomAD
rs1196806613 CA383598466	1335	N>K		No	ClinGen gnomAD
rs150713925 CA6409267	1335	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA383598478 rs1400660777	1336	D>H		No	ClinGen gnomAD
CA383598532 rs768266220	1337	F>L		No	ClinGen ExAC gnomAD
CA383598538 rs1200971862	1338	V>L		No	ClinGen TOPMed
CA6409271 rs369464603	1340	P>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA383598593 rs1278156529	1340	P>L		No	ClinGen TOPMed
CA6409270 COSM942602 rs369464603	1340	P>S	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs202123025 CA6409272	1341	E>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs759914474 CA6409273 COSM162817	1343	R>C	NS [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs759914474 CA383598659	1343	R>G		No	ClinGen ExAC TOPMed gnomAD
CA6409274 rs767960393	1343	R>H		No	ClinGen ExAC TOPMed gnomAD
rs767960393 CA383598664	1343	R>P		No	ClinGen ExAC TOPMed gnomAD
rs759914474 CA383598661	1343	R>S		No	ClinGen ExAC TOPMed gnomAD
rs768229078 CA6409275	1344	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6409276 rs760736035	1344	R>H	Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA383598669 rs768229078	1344	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1281582496 CA383598693	1345	T>A		No	ClinGen gnomAD
CA6409277 rs764167695	1346	T>P		No	ClinGen ExAC gnomAD
rs373233854 CA6409279	1347	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409280 rs373233854	1347	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6409281 rs140382418	1347	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6409283 rs779911821	1348	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs758188413 CA6409282	1348	R>W		No	ClinGen ExAC gnomAD
CA232396246 rs200908224	1349	H>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA232396259 rs998886798	1350	P>S		No	ClinGen TOPMed gnomAD
CA383598836 rs1200554459	1352	T>S		No	ClinGen gnomAD
TCGA novel	1353	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1031646703 CA232396262	1353	Q>R		No	ClinGen Ensembl
rs1379696785 CA383598873	1354	Q>E		No	ClinGen gnomAD
CA232396271 rs960416335	1355	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs370927177 CA6409286	1355	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA383598984 rs1167823875	1359	K>T		No	ClinGen gnomAD
CA383599025 rs1431688133	1361	P>R		No	ClinGen gnomAD
rs1371760448 CA383599016	1361	P>S		No	ClinGen gnomAD
CA383599068 rs1444213061	1363	V>F		No	ClinGen TOPMed
CA383599102 rs1241576207	1365	F>L		No	ClinGen TOPMed
CA6409287 rs747621834	1365	F>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1368	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6409288 rs769611228	1369	E>G		No	ClinGen ExAC TOPMed gnomAD
CA232396297 rs1014299559	1372	E>K		No	ClinGen TOPMed
CA383599937 rs1424467625	1374	D>E		No	ClinGen gnomAD
CA6409309 rs770435927	1374	D>G		No	ClinGen ExAC TOPMed gnomAD
CA232396537 rs548656569	1375	L>P		No	ClinGen TOPMed gnomAD
CA383600024 rs1362150753	1378	E>D		No	ClinGen gnomAD
rs1160225683 CA383600074	1379	M>I		No	ClinGen gnomAD
CA383600033 rs1470042306	1379	M>L		No	ClinGen gnomAD
RCV000950774 rs61752289 CA6409311	1383	E>K		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
COSM549632 rs747329947 CA6409312	1384	T>I	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA6409314 rs769187957	1386	K>E		No	ClinGen ExAC TOPMed gnomAD
rs769187957 CA6409313	1386	K>Q		No	ClinGen ExAC TOPMed gnomAD
COSM3704360 rs1176240536 CA383600285	1386	K>R	liver [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1479735181 CA383600305	1387	K>E		No	ClinGen TOPMed
CA383600340 rs1592180197	1389	T>P		No	ClinGen Ensembl
CA6409315 rs140130874	1390	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6409316 rs140130874	1390	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1334688291 CA383600418	1392	L>P		No	ClinGen gnomAD
CA6409317 rs773097640	1394	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA
CA6409318 rs763249981	1395	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6409320 rs751412550	1396	A>T		No	ClinGen ExAC gnomAD
rs1202243479 CA383600514	1397	R>C		No	ClinGen TOPMed gnomAD
rs545349359 CA6409322	1397	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6409321 rs545349359	1397	R>P		No	ClinGen ExAC TOPMed gnomAD
CA232396616 rs202191153	1398	R>M		No	ClinGen 1000Genomes
CA383600624 rs1354052146	1402	S>W		No	ClinGen TOPMed gnomAD
CA383600633 rs1184117022	1402	S>Y		No	ClinGen gnomAD

1 associated diseases with Q15021

[MIM: 617983]: Microcephaly 21, primary, autosomal recessive (MCPH21)

A form of microcephaly, a disease defined as a head circumference more than 3 standard deviations below the age, sex and ethnically matched mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. MCPH21 features include mild intellectual disability, intrauterine growth retardation, short stature, and microcephaly. {ECO:0000269|PubMed:27737959, ECO:0000269|PubMed:28097321}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID

A form of microcephaly, a disease defined as a head circumference more than 3 standard deviations below the age, sex and ethnically matched mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. MCPH21 features include mild intellectual disability, intrauterine growth retardation, short stature, and microcephaly. {ECO:0000269|PubMed:27737959, ECO:0000269|PubMed:28097321}. Note=The disease is caused by variants affecting the gene represented in this entry.

2 regional properties for Q15021

Type	Name	Position	InterPro Accession
domain	Condensin complex subunit 1, N-terminal	77 - 240	IPR024324
domain	Condensin complex subunit 1, C-terminal	1070 - 1230	IPR032682

Functions

		Description
EC Number
Subcellular Localization	Nucleus Cytoplasm Chromosome	In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin A subpopulation of the complex however remains associated with chromosome foci in interphase cells During mitosis, most of the condensin complex is associated with the chromatin At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation Dissociation from chromosomes is observed in late telophase
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

8 GO annotations of cellular component

Name	Definition
condensed chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
condensed chromosome, centromeric region	The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
condensin complex	A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name	Definition
histone binding	Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.

4 GO annotations of biological process

Name	Definition
cell division	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
meiotic chromosome condensation	Compaction of chromatin structure prior to meiosis in eukaryotic cells.
mitotic chromosome condensation	The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
positive regulation of chromosome condensation	Any process that activates or increases the frequency, rate or extent of chromosome condensation.

2 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P42695	NCAPD3	Condensin-2 complex subunit D3	Homo sapiens (Human)	PR
Q8K2Z4	Ncapd2	Condensin complex subunit 1	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MAPQMYEFHL	PLSPEELLKS	GGVNQYVVQE	VLSIKHLPPQ	LRAFQAAFRA	QGPLAMLQHF
70	80	90	100	110	120
DTIYSILHHF	RSIDPGLKED	TLQFLIKVVS	RHSQELPAIL	DDTTLSGSDR	NAHLNALKMN
130	140	150	160	170	180
CYALIRLLES	FETMASQTNL	VDLDLGGKGK	KARTKAAHGF	DWEEERQPIL	QLLTQLLQLD
190	200	210	220	230	240
IRHLWNHSII	EEEFVSLVTG	CCYRLLENPT	INHQKNRPTR	EAITHLLGVA	LTRYNHMLSA
250	260	270	280	290	300
TVKIIQMLQH	FEHLAPVLVA	AVSLWATDYG	MKSIVGEIVR	EIGQKCPQEL	SRDPSGTKGF
310	320	330	340	350	360
AAFLTELAER	VPAILMSSMC	ILLDHLDGEN	YMMRNAVLAA	MAEMVLQVLS	GDQLEAAARD
370	380	390	400	410	420
TRDQFLDTLQ	AHGHDVNSFV	RSRVLQLFTR	IVQQKALPLT	RFQAVVALAV	GRLADKSVLV
430	440	450	460	470	480
CKNAIQLLAS	FLANNPFSCK	LSDADLAGPL	QKETQKLQEM	RAQRRTAAAS	AVLDPEEEWE
490	500	510	520	530	540
AMLPELKSTL	QQLLQLPQGE	EEIPEQIANT	ETTEDVKGRI	YQLLAKASYK	KAIILTREAT
550	560	570	580	590	600
GHFQESEPFS	HIDPEESEET	RLLNILGLIF	KGPAASTQEK	NPRESTGNMV	TGQTVCKNKP
610	620	630	640	650	660
NMSDPEESRG	NDELVKQEML	VQYLQDAYSF	SRKITEAIGI	ISKMMYENTT	TVVQEVIEFF
670	680	690	700	710	720
VMVFQFGVPQ	ALFGVRRMLP	LIWSKEPGVR	EAVLNAYRQL	YLNPKGDSAR	AKAQALIQNL
730	740	750	760	770	780
SLLLVDASVG	TIQCLEEILC	EFVQKDELKP	AVTQLLWERA	TEKVACCPLE	RCSSVMLLGM
790	800	810	820	830	840
MARGKPEIVG	SNLDTLVSIG	LDEKFPQDYR	LAQQVCHAIA	NISDRRKPSL	GKRHPPFRLP
850	860	870	880	890	900
QEHRLFERLR	ETVTKGFVHP	DPLWIPFKEV	AVTLIYQLAE	GPEVICAQIL	QGCAKQALEK
910	920	930	940	950	960
LEEKRTSQED	PKESPAMLPT	FLLMNLLSLA	GDVALQQLVH	LEQAVSGELC	RRRVLREEQE
970	980	990	1000	1010	1020
HKTKDPKEKN	TSSETTMEEE	LGLVGATADD	TEAELIRGIC	EMELLDGKQT	LAAFVPLLLK
1030	1040	1050	1060	1070	1080
VCNNPGLYSN	PDLSAAASLA	LGKFCMISAT	FCDSQLRLLF	TMLEKSPLPI	VRSNLMVATG
1090	1100	1110	1120	1130	1140
DLAIRFPNLV	DPWTPHLYAR	LRDPAQQVRK	TAGLVMTHLI	LKDMVKVKGQ	VSEMAVLLID
1150	1160	1170	1180	1190	1200
PEPQIAALAK	NFFNELSHKG	NAIYNLLPDI	ISRLSDPELG	VEEEPFHTIM	KQLLSYITKD
1210	1220	1230	1240	1250	1260
KQTESLVEKL	CQRFRTSRTE	RQQRDLAYCV	SQLPLTERGL	RKMLDNFDCF	GDKLSDESIF
1270	1280	1290	1300	1310	1320
SAFLSVVGKL	RRGAKPEGKA	IIDEFEQKLR	ACHTRGLDGI	KELEIGQAGS	QRAPSAKKPS
1330	1340	1350	1360	1370	1380
TGSRYQPLAS	TASDNDFVTP	EPRRTTRRHP	NTQQRASKKK	PKVVFSSDES	SEEDLSAEMT
1390	1400
EDETPKKTTP	ILRASARRHR	S