Q0VCW8

PR
Gene name
PDCL3
Protein name
Phosducin-like protein 3
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:514033
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-122 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0VCW8

Entry ID Method Resolution Chain Position Source
AF-Q0VCW8-F1 Predicted AlphaFoldDB

No variants for Q0VCW8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0VCW8

No associated diseases with Q0VCW8

1 regional properties for Q0VCW8

Type Name Position InterPro Accession
domain Phosducin, thioredoxin-like domain 33 - 181 IPR024253

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasm, perinuclear region
  • Endoplasmic reticulum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
perinuclear region of cytoplasm Cytoplasm situated near, or occurring around, the nucleus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H2J4 PDCL3 Phosducin-like protein 3 Homo sapiens (Human) PR
Q8BVF2 Pdcl3 Phosducin-like protein 3 Mus musculus (Mouse) PR
10 20 30 40 50 60
MQDPNADTEW NDILRKKGIL PSKEDLKDLE KEAEEEEQRI LQQSIVKTYE DMTLEELEDN
70 80 90 100 110 120
EDEFNEEDER AIEMYRQQRL AEWKATQLKN KFGEVLEISG KDYVQEVTKA GEGLWVILHL
130 140 150 160 170 180
YKQGIPLCAL INQHLSALAR KFPDVKFIKA ISTTCIPSYP DRNLPTVFVY LEGDIKAQFI
190 200 210 220 230
GPLVFGGMNL TLDELEWKLS ESGAIKTSLE ENPKKPVEDV LLSAVRCSVP AKRDSDSEDD