Q0V9Z3

PR
Gene name
pacc1
Protein name
Proton-activated chloride channel
Names
PAC, Transmembrane protein 206
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:779750
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0V9Z3

Entry ID Method Resolution Chain Position Source
AF-Q0V9Z3-F1 Predicted AlphaFoldDB

No variants for Q0V9Z3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0V9Z3

No associated diseases with Q0V9Z3

No regional properties for Q0V9Z3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0V9Z3

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloride channel complex An ion channel complex through which chloride ions pass.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
pH-gated chloride channel activity A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.

1 GO annotations of biological process

Name Definition
chloride transport The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2KHV2 PACC1 Proton-activated chloride channel Bos taurus (Bovine) PR
Q9H813 PACC1 Proton-activated chloride channel Homo sapiens (Human) PR
Q9D771 Pacc1 Proton-activated chloride channel Mus musculus (Mouse) PR
Q66H28 Pacc1 Proton-activated chloride channel Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MEAIRKELSR SYQELNEEAE PVAIDPEEAE DEEKEQEEAA SAVAPDRDSD RSSPPVRFSR
70 80 90 100 110 120
TCLKNFFSVL LILVYLLLMG VAVFLVYQTI TDFRDKLKHP VMSVSYKEVN MYDAPGIALY
130 140 150 160 170 180
PGKARLLSCE HHWYDHIPPL KDPGQPGENT CVTQDISYID PYTNKTMKHA LIVQGPRDVR
190 200 210 220 230 240
RRELVFLQFH LNETKQDFSA IDYLLFSSYE AFLKSHDQVK FMQDCESSFS SWKFSGGFRT
250 260 270 280 290 300
WVKMSLVKTK EEDGSQSVEF RQETSVVNFI DRRETPDKGD QLFFVVFEWK DPYIQEIQDI
310 320 330 340 350
ITANPWSMIA LLCSVFLVLF KAADFAKLSV KWMIKVRRRH LKKRARELNH IS