Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0V7W6

Entry ID Method Resolution Chain Position Source
AF-Q0V7W6-F1 Predicted AlphaFoldDB

41 variants for Q0V7W6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06749863 14 P>T No 1000Genomes
ENSVATH14277603 26 G>* No 1000Genomes
tmp_4_11713859_C_T 30 V>M No 1000Genomes
ENSVATH12134381 38 P>S No 1000Genomes
ENSVATH12134380 44 V>L No 1000Genomes
ENSVATH02905993 49 I>M No 1000Genomes
tmp_4_11713799_A_T 50 C>S No 1000Genomes
ENSVATH06749862 63 I>L No 1000Genomes
tmp_4_11713758_T_C 63 I>M No 1000Genomes
tmp_4_11713648_C_T 73 R>K No 1000Genomes
ENSVATH14277601 98 V>G No 1000Genomes
ENSVATH02905989 98 V>I No 1000Genomes
tmp_4_11713455_T_C 111 R>G No 1000Genomes
ENSVATH00530254 129 L>* No 1000Genomes
tmp_4_11713382_T_C 135 Y>C No 1000Genomes
tmp_4_11713349_C_T 146 G>E No 1000Genomes
ENSVATH06749848 171 K>R No 1000Genomes
tmp_4_11713064_C_T 196 W>* No 1000Genomes
tmp_4_11713042_C_T 204 G>S No 1000Genomes
tmp_4_11713020_C_T 211 G>D No 1000Genomes
ENSVATH02905982 212 L>I No 1000Genomes
tmp_4_11712878_C_G 229 G>R No 1000Genomes
tmp_4_11712863_C_T 234 V>I No 1000Genomes
tmp_4_11712853_T_C 237 N>S No 1000Genomes
ENSVATH12134351 242 E>D No 1000Genomes
ENSVATH02905945 251 D>G No 1000Genomes
ENSVATH02905946 251 D>N No 1000Genomes
ENSVATH00530248 255 S>P No 1000Genomes
ENSVATH12134274 261 N>I No 1000Genomes
ENSVATH00530247 261 N>K No 1000Genomes
tmp_4_11712044_C_T 274 G>E No 1000Genomes
ENSVATH06749795 282 V>L No 1000Genomes
ENSVATH12134266 290 E>Q No 1000Genomes
ENSVATH06749793 313 P>Q No 1000Genomes
ENSVATH06749792 317 G>D No 1000Genomes
ENSVATH12134201 342 P>L No 1000Genomes
ENSVATH14277554 345 V>I No 1000Genomes
ENSVATH06749775 352 E>K No 1000Genomes
tmp_4_11711520_A_T 358 F>I No 1000Genomes
ENSVATH02905936 366 E>V No 1000Genomes
ENSVATH00530242 374 L>F No 1000Genomes

No associated diseases with Q0V7W6

1 regional properties for Q0V7W6

Type Name Position InterPro Accession
domain F-box domain 1 - 44 IPR001810

Functions

Description
EC Number 1.1.1.1 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
alcohol dehydrogenase activity, zinc-dependent Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
S-(hydroxymethyl)glutathione dehydrogenase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
formaldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9FH04 At5g42250 Alcohol dehydrogenase-like 7 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEKTSMFSIH EGKPIRCKAA VSRKPGEALV IEEIHVDPPQ AYEVRIKIIC TSLCHTDVSF
70 80 90 100 110 120
SKIDSGPLAR FPRILGHEAV GVIESIGEHV NGFQQGDVVL PVFHPHCEEC RDCKSSKSNW
130 140 150 160 170 180
CARFADDFLS NTRRYGMTSR FKDSFGEDIY HFLFVSSFSE YTVVDIAHLV KISPDIPVDK
190 200 210 220 230 240
AALLSCGVST GIGAAWKVAN VEKGSTVAVF GLGAVGLAVG EGARLRGAGK IIGVDLNPEK
250 260 270 280 290 300
FELGKKFGFT DFINSTLCGE NKISEVIKEM TGGGVDYSFE CVGLPSLLTE AFSSTRTGSG
310 320 330 340 350 360
KTVVLGIDKH LTPVSLGSFD LLRGRHVCGS LFGGLKPKLD IPILVDHYLK KELNLDSFIT
370 380
HELKFEEINK AFDLLVQGKS LRCILWMNK