Q0P5C0

PR
Gene name
LMF1 (TMEM112)
Protein name
Lipase maturation factor 1
Names
Transmembrane protein 112
Species
Bos taurus (Bovine)
KEGG Pathway
bta:505124
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0P5C0

Entry ID Method Resolution Chain Position Source
AF-Q0P5C0-F1 Predicted AlphaFoldDB

No variants for Q0P5C0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0P5C0

No associated diseases with Q0P5C0

No regional properties for Q0P5C0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0P5C0

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein maturation Any process leading to the attainment of the full functional capacity of a protein.
triglyceride metabolic process The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96S06 LMF1 Lipase maturation factor 1 Homo sapiens (Human) PR
Q3U3R4 Lmf1 Lipase maturation factor 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAAPRESLRR RKAGAGDPEP EAPPGQGRDL KGRPARLRAG TFWLTRIVLL RALAFVYFVA
70 80 90 100 110 120
FLVAFHQNKQ LIGDRGLLPC RAYLQSVQRH FGGRVSWDAL SYAPTILWLL DWSHMDANLD
130 140 150 160 170 180
ALALLGLGIS SFILVSGCAN MVLMAALWVL YMSLVNVGQI WYSFGWESQL LETGFLGIFL
190 200 210 220 230 240
CPLWTLSALP RGTPTSWVVM WGFRWLIFRI MLGAGLIKIR GDRCWRDLTC MDFHYETQPV
250 260 270 280 290 300
PNPVAYFLHR SPWWFHRFET LSNHFLELVV PFFIFLGRRM CIVHGALQVL FQVVLIISGN
310 320 330 340 350 360
LSFLNWLTIV PSLACFDDAT LGGLFPSGPG RLKDQVLKIQ EEETRGARAP RTRGSVARGT
370 380 390 400 410 420
VNLALGILVA WLSIPVVLNL LSPRQVMNSS FNPLRIVNTY GAFGSITRER TEVILQGTAS
430 440 450 460 470 480
ANASAPDSAW EDYEFKCKPG DPRRRPCLIS PYHHRLDWLM WFAAFQTYEH NEWIIHLAGK
490 500 510 520 530 540
LLANDAQALS LLARNPFEGR DPPRWVRGEH YRYKFSRPGG RHAAEGKWWI RRRLGPYFPP
550 560
LSRQDLRGYF TSRQWPYPEP E