Q06593
PR
Gene name |
OPT2 (YPR194C, P9677.13) |
Protein name |
Oligopeptide transporter 2 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YPR194C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q06593
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q06593-F1 | Predicted | AlphaFoldDB |
38 variants for Q06593
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s16-926645 | 97 | K>E | No | SGRP | |
| s16-926558 | 126 | D>N | No | SGRP | |
| s16-926488 | 149 | V>G | No | SGRP | |
| s16-926486 | 150 | R>G | No | SGRP | |
| s16-926470 | 155 | P>R | No | SGRP | |
| s16-926453 | 161 | I>F | No | SGRP | |
| s16-926450 | 162 | P>T | No | SGRP | |
| s16-926446 | 163 | V>G | No | SGRP | |
| s16-926382 | 184 | E>D | No | SGRP | |
| s16-926375 | 187 | S>A | No | SGRP | |
| s16-926348 | 196 | N>D | No | SGRP | |
| s16-926347 | 196 | N>S | No | SGRP | |
| s16-926279 | 219 | T>A | No | SGRP | |
| s16-926229 | 235 | W>* | No | SGRP | |
| s16-926222 | 238 | K>E | No | SGRP | |
| s16-926206 | 243 | S>* | No | SGRP | |
| s16-926177 | 253 | A>T | No | SGRP | |
| s16-926035 | 300 | Y>F | No | SGRP | |
| s16-925894 | 347 | W>* | No | SGRP | |
| s16-925836 | 366 | K>N | No | SGRP | |
| s16-925744 | 397 | F>Y | No | SGRP | |
| s16-925742 | 398 | N>Y | No | SGRP | |
| s16-925730 | 402 | V>I | No | SGRP | |
| s16-925694 | 414 | G>S | No | SGRP | |
| s16-925589 | 449 | H>D | No | SGRP | |
| s16-925580 | 452 | K>E | No | SGRP | |
| s16-925568 | 456 | V>I | No | SGRP | |
| s16-925555 | 460 | D>G | No | SGRP | |
| s16-925493 | 481 | L>V | No | SGRP | |
| s16-925487 | 483 | S>A | No | SGRP | |
| s16-925487 | 483 | S>T | No | SGRP | |
| s16-925398 | 512 | D>E | No | SGRP | |
| s16-925168 | 589 | C>S | No | SGRP | |
| s16-924969 | 655 | I>M | No | SGRP | |
| s16-924911 | 675 | F>L | No | SGRP | |
| s16-924608 | 776 | S>G | No | SGRP | |
| s16-924424 | 837 | T>I | No | SGRP | |
| s16-924400 | 845 | T>K | No | SGRP |
No associated diseases with Q06593
No regional properties for Q06593
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q06593 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| fungal-type vacuole | A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. |
| Golgi trans cisterna | The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| oligopeptide transmembrane transporter activity | Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| cell redox homeostasis | Any process that maintains the redox environment of a cell or compartment within a cell. |
| oligopeptide transport | The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. |
| positive regulation of monopolar cell growth | Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of phospholipid translocation | Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
| regulation of vacuole organization | Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. |
| vacuole fusion, non-autophagic | The fusion of two vacuole membranes to form a single vacuole. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P40897 | OPT1 | Oligopeptide transporter 1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSETVKDKVI | IDEKVSTKGT | VDYAEGAEYS | ERLSNHSSDF | SQWYTDEQIL | HFMKKLGYEN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RTLYDIPEDV | AYILKKMPEL | TLEDSFKILK | DSIIYFKDDE | NIPHDQYEEW | KRLVDLEDLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SKEGIDEYDS | FDIRAFASAI | KFHSPYQEVR | AVVDPEDDPT | IPVETFRAYF | LAIIWSVIGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GFNEFFSHRV | VSISLNTPII | QMFLYICGKA | WAKTIPCWTI | TIRGRKYGIN | IDKPWTQKEQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MFSTLLYAIC | QGAFYTHYNI | LTQKLFYHSA | FSFGYQFLLS | LSVQFIGFGF | AGILRKFVVY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PARALWPTVM | PTIAINKALL | GKEKHESGMS | RYKFFFLTFF | IMFIYNWFPT | YIINILNTFN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WMTWIKPSNI | NLANITGGVT | GLGINPISSF | DWNVISFNSP | LVYPFWSYLT | QYLGCILAAL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IVIAVYYSNY | MSCQYLPIFT | NSLYTNTGHS | FKVTEVLDSD | NKLDVKKYQS | YSPPYYSAGN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LVSYGAFICA | YPLMITWSFI | VHSKLLFNAF | KDWALNLWAM | RKLKSWVTMF | KSDYRALDDY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DDPHSNAMKN | YKEVPDWWYF | AILIGSLVVG | IAVVEHYPTN | TPVWGLFVCL | GFNFVFLIPT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TILQATTGYS | FGLNLLIEMV | MGYALPGNPI | AIMILKAFGY | NIDGQADNYV | SNLKIAHYCK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IPPMALFRGQ | CVIVFIQIFV | NLGVLNWQIS | NIKDFCTPHQ | NAKFTCPDAV | TYYNASVVWG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| AIGPKRIFNY | IYPIFKWCWL | IGACIGIFFG | VWKRWGKFYP | RYFDPMLFVG | GMLNMSPPYN |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LMYYTSGMIV | SYISQYYMKR | HHLNLWEKYN | YVLSAGFSTG | LVLSAIIIFF | AVQYKDTAFN |
| 850 | 860 | 870 | |||
| WWGNTVPYAG | ADGVGYPLKN | ITDTANGYFG | YAPGHYP |