P40897
Gene name |
OPT1 (GSH11, HGT1, YJL212C, HRD799, J0236) |
Protein name |
Oligopeptide transporter 1 |
Names |
High affinity glutathione transporter 1 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YJL212C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40897
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40897-F1 | Predicted | AlphaFoldDB |
17 variants for P40897
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s10-36219 | 11 | L>V | No | SGRP | |
| s10-36168 | 28 | M>V | No | SGRP | |
| s10-36159 | 31 | E>K | No | SGRP | |
| s10-36050 | 67 | S>F | No | SGRP | |
| s10-35651 | 200 | A>V | No | SGRP | |
| s10-35625 | 209 | L>F | No | SGRP | |
| s10-34959 | 431 | S>A | No | SGRP | |
| s10-34935 | 439 | V>I | No | SGRP | |
| s10-34837 | 471 | R>S | No | SGRP | |
| s10-34692 | 520 | L>F | No | SGRP | |
| s10-34488 | 588 | S>P | No | SGRP | |
| s10-34461 | 597 | I>V | No | SGRP | |
| s10-34382 | 623 | T>S | No | SGRP | |
| s10-34341 | 637 | T>A | No | SGRP | |
| s10-34176 | 692 | H>N | No | SGRP | |
| s10-33936 | 772 | V>I | No | SGRP | |
| s10-33926 | 775 | R>K | No | SGRP |
No associated diseases with P40897
No regional properties for P40897
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P40897 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| oligopeptide transmembrane transporter activity | Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. |
| proton-dependent oligopeptide secondary active transmembrane transporter activity | Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| oligopeptide transport | The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06593 | OPT2 | Oligopeptide transporter 2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTIYRESDS | LESEPSPTPT | TIPIQINMEE | EKKDAFVKNI | DEDVNNLTAT | TDEEDRDPES |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QKFDRHSIQE | EGLVWKGDPT | YLPNSPYPEV | RSAVSIEDDP | TIRLNHWRTW | FLTTVFVVVF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AGVNQFFSLR | YPSLEINFLV | AQVVCYPIGR | ILALLPDWKC | SKVPFFDLNP | GPFTKKEHAV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTIAVALTSS | TAYAMYILNA | QGSFYNMKLN | VGYQFLLVWT | SQMIGYGAAG | LTRRWVVNPA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSIWPQTLIS | VSLFDSLHSR | KVEKTVANGW | TMPRYRFFLI | VLIGSFIWYW | VPGFLFTGLS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YFNVILWGSK | TRHNFIANTI | FGTQSGLGAL | PITFDYTQVS | QAMSGSVFAT | PFYVSANTYA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SVLIFFVIVL | PCLYFTNTWY | AKYMPVISGS | TYDNTQNKYN | VTKILNEDYS | INLEKYKEYS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PVFVPFSYLL | SYALNFAAVI | AVFVHCILYH | GKDIVAKFKD | RKNGGTDIHM | RIYSKNYKDC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PDWWYLLLQI | VMIGLGFVAV | CCFDTKFPAW | AFVIAILISL | VNFIPQGILE | AMTNQHVGLN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IITELICGYM | LPLRPMANLL | FKLYGFIVMR | QGLNLSRDLK | LAMYMKVSPR | LIFAVQIYAT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IISGMVNVGV | QEWMMHNIDG | LCTTDQPNGF | TCANGRTVFN | ASIIWSLPKY | LFSSGRIYNP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LMWFFLIGLL | FPLAVYAVQW | KFPKFKFAKH | IHTPVFFTGP | GNIPPSTPYN | YSLFFAMSFC |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LNLIRKRWRA | WFNKYNFVMG | AGVEAGVAIS | VVIIFLCVQY | PGGKLSWWGN | NVWKRTYDND |
| 790 | |||||
| YKKFYTLKKG | ETFGYDKWW |