Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q02862

Entry ID Method Resolution Chain Position Source
AF-Q02862-F1 Predicted AlphaFoldDB

14 variants for Q02862

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3395743806 21 D>ALTSLEDLSFISCIN* No EVA
rs225726808 47 T>A No EVA
rs3388753109 84 F>L No EVA
rs3388761558 94 S>P No EVA
rs1132211729 97 C>G No EVA
rs1133260970 103 Q>K No EVA
rs1133864652 107 S>I No EVA
rs3388739725 108 V>G No EVA
rs1132596348 113 Q>L No EVA
rs247297937 120 T>M No EVA
rs13459685 122 T>N No EVA
rs225826896 140 M>I No EVA
rs3388761544 154 L>P No EVA
rs3388771897 157 A>S No EVA

No associated diseases with Q02862

1 regional properties for Q02862

Type Name Position InterPro Accession
domain ThiC-associated domain 17 - 72 IPR025747

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

2 GO annotations of molecular function

Name Definition
protein homodimerization activity Binding to an identical protein to form a homodimer.
zymogen binding Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P02664 Csn1s2b Alpha-S2-casein-like B Mus musculus (Mouse) PR
Q8CGR3 Csn1s2b Alpha-S2-casein-like B Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKFFIFACLV VVALAKHEIK DKSSSEESSA SIYPGKSKLD NSVFFQTTKD SASSSSSEES
70 80 90 100 110 120
SEEVSEKIVQ SEEQKVNLNQ QKKFKQFSQE SSFSQCCTPL HQQQQSSVNQ WPQPNAIHNT
130 140 150 160 170 180
PTQESISTSV EEILKKIIDM IKYIQYQQVT IPQLPQALHP QIPVSYWYPS KDYTFPNAHY
TRFY