P02664

PR
Gene name
Csn1s2b (Csnd, Csne)
Protein name
Alpha-S2-casein-like B
Names
Casein alpha S2-like B, Epsilon-casein
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:12992
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

57-126 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P02664

Entry ID Method Resolution Chain Position Source
AF-P02664-F1 Predicted AlphaFoldDB

9 variants for P02664

Variant ID(s) Position Change Description Diseaes Association Provenance
rs37744788 12 V>I No EVA
rs38382545 41 D>N No EVA
rs240503620 43 A>V No EVA
rs261007889 55 Y>H No EVA
rs37146674 64 A>V No EVA
rs243986225 66 M>I No EVA
rs3388769098 101 I>T No EVA
rs3388754913 102 Q>H No EVA
rs221311562 110 R>Q No EVA

No associated diseases with P02664

1 regional properties for P02664

Type Name Position InterPro Accession
conserved_site Casein alpha/beta, conserved site 8 - 15 IPR031305

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

2 GO annotations of molecular function

Name Definition
protein homodimerization activity Binding to an identical protein to form a homodimer.
zymogen binding Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q02862 Csn1s2a Alpha-S2-casein-like A Mus musculus (Mouse) PR
Q8CGR3 Csn1s2b Alpha-S2-casein-like B Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKFIILTCLL AVALAKQRME QYISSEESMD NSQENFKQNM DVAFFPSQET VENIYIPQME
70 80 90 100 110 120
SVEAPMKVSD IISQQQYNQK MMDMSVSARE KTVMTEESKN IQDYMNKMKR YSKITWPQFV
130 140
KLLHQYQKTM TPWSYYPSTP SQV