P97878
Gene name |
Exoc5 (Sec10l1) |
Protein name |
Exocyst complex component 5 |
Names |
71 kDa component of rsec6/8 secretory complex, Exocyst complex component Sec10, p71 |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:60627 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P97878
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P97878-F1 | Predicted | AlphaFoldDB |
No variants for P97878
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P97878 | |||||
No associated diseases with P97878
No regional properties for P97878
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P97878 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. |
| midbody | A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein N-terminus binding | Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. |
| small GTPase binding | Binding to a small monomeric GTPase. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| epithelial cell apoptotic process | Any apoptotic process in an epithelial cell. |
| establishment of planar polarity | Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| Golgi to plasma membrane transport | The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. |
| non-motile cilium assembly | The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. |
| protein localization to plasma membrane | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P39531 | RCY1 | Recyclin-1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATTAELFEE | PFVADEYIER | LVWRTPGGGS | RGGPEAFDPK | RLLEEFVNHI | QELQIMDERI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QRKVEKLEQQ | CQKEAKEFAK | KVQELQKSNQ | VAFQHFQELD | EHISYVATKV | CHLGDQLEGV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NTPRQRAVEA | QKLMKYFNEF | LDGELKSDVF | TNPEKIKEAA | DVIQKLHLIA | QELPFDRFSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKSKIASKYH | DLECQLIQEF | TSAQRRGEVS | RMREVAAVLL | HFKGYSHCID | VYIKQCQEGA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YLRNDIFEDA | AILCQRVNKQ | VGDIFSNPEA | VLAKLIQNVF | EVKLQSFVKD | QLEECRKSDA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQYLKSLYDL | YTRTTSLSSK | LMEFNLGTDK | QTFLSKLIKS | IFVSYLENYI | EVEIGYLKSR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SAMILQRYYD | SKNHQKRSIG | TGGIQDLKER | IRQRTNLPLG | PSIDTHGETF | LSQEVVVNLL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QETKQAFERC | HRLSDPSDLP | RNAFRIFTIL | VEFLCIEHID | YALETGLAGI | PSSDSRNANL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YFLDVVQQAN | TIFHLFDKQF | NDHLMPLISS | SPKLSECLQK | KKEIIEQMEM | KLDTGIDRTL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NCMIGQMKHI | LAAEQKKTDF | KPEDENNVLI | QYTNACVKVC | AYVRKQVEKI | KNSMDGKNVD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TVLMELGVRF | HRLTYEHLQQ | YSYSCMGGML | AICDVAEYRK | CAKDFKIPMV | LHLFDTLHAL |
| 670 | 680 | 690 | 700 | ||
| CNLLVVAPDN | LKQVCSGEQL | ANLDKNILHS | FVQLRADYRS | ARLARHFS |