P77744

PR
Gene name
abgR (b1339, JW1333)
Protein name
HTH-type transcriptional regulator AbgR
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b1339
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P77744

Entry ID Method Resolution Chain Position Source
AF-P77744-F1 Predicted AlphaFoldDB

No variants for P77744

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P77744

No associated diseases with P77744

4 regional properties for P77744

Type Name Position InterPro Accession
domain Aspartate/glutamate/uridylate kinase 10 - 239 IPR001048
domain PUA domain 282 - 365 IPR002478
conserved_site Glutamate 5-kinase, conserved site 212 - 229 IPR019797
domain Glutamate-5-kinase domain 16 - 261 IPR041739

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0A9F9 metR HTH-type transcriptional regulator MetR Escherichia coli (strain K12) PR
10 20 30 40 50 60
MAFQVKIHQI RAFVEVARQG SIRGASRMLN MSQPALSKSI QELEEGLAAQ LFFRRSKGVT
70 80 90 100 110 120
LTDAGESFYQ HASLILEELR AAQEDIRQRQ GQLAGQINIG MGASISRSLM PAVISRFHQQ
130 140 150 160 170 180
HPQVKVRIME GQLVSMINEL RQGELDFTIN TYYQGPYDHE FTFEKLLEKQ FAIFCRPGHP
190 200 210 220 230 240
AIGARSIKQL LDYSWTMPTP HGSYYKQLSE LLDDQAQTPQ VGVVCETFSA CISLVAKSDF
250 260 270 280 290 300
LSKLPEEMGC DPLHGQGLVM LPVSEILPKA AYYLIQRRDS RQTPLTASLI TQFRRECGYL
QS