P76318

PR
Gene name
yedK
Protein name
Abasic site processing protein YedK
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b1931
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

144-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

11 structures for P76318

Entry ID Method Resolution Chain Position Source
2ICU X-ray 160 A A/B 1-222 PDB
6KBS X-ray 160 A B 2-222 PDB
6KBU X-ray 210 A A/B 2-222 PDB
6KBX X-ray 122 A B 2-222 PDB
6KBZ X-ray 165 A B/D/F/H 2-222 PDB
6KCQ X-ray 170 A B 1-222 PDB
6KIJ X-ray 158 A B 2-222 PDB
6NUA X-ray 164 A A/B 2-222 PDB
6NUH X-ray 159 A A 2-222 PDB
8D2M X-ray 182 A A/B 2-222 PDB
AF-P76318-F1 Predicted AlphaFoldDB

No variants for P76318

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P76318

No associated diseases with P76318

1 regional properties for P76318

Type Name Position InterPro Accession
domain Luciferase-like domain 12 - 234 IPR011251

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
single-stranded DNA binding Binding to single-stranded DNA.

4 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
protein-DNA covalent cross-linking The formation of a covalent cross-link between DNA and a protein.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
SOS response An error-prone process for repairing damaged microbial DNA.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q04471 YMR114C Abasic site processing protein YMR114C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
10 20 30 40 50 60
MCGRFAQSQT REDYLALLAE DIERDIPYDP EPIGRYNVAP GTKVLLLSER DEHLHLDPVF
70 80 90 100 110 120
WGYAPGWWDK PPLINARVET AATSRMFKPL WQHGRAICFA DGWFEWKKEG DKKQPFFIYR
130 140 150 160 170 180
ADGQPIFMAA IGSTPFERGD EAEGFLIVTA AADQGLVDIH DRRPLVLSPE AAREWMRQEI
190 200 210 220
SGKEASEIAA SGCVPANQFS WHPVSRAVGN VKNQGAELIQ PV