P76016

PR
Gene name
dhaR
Protein name
PTS-dependent dihydroxyacetone kinase operon regulatory protein
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b1201
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for P76016

Entry ID Method Resolution Chain Position Source
4LRX X-ray 325 A C/D 1-318 PDB
4LRY X-ray 283 A C/D 1-318 PDB
4LRZ X-ray 232 A E/F/G/H 1-318 PDB
AF-P76016-F1 Predicted AlphaFoldDB

No variants for P76016

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P76016

No associated diseases with P76016

7 regional properties for P76016

Type Name Position InterPro Accession
domain PAS domain 203 - 303 IPR000014
domain RNA polymerase sigma factor 54 interaction domain 327 - 552 IPR002078
domain DNA binding HTH domain, Fis-type 588 - 627 IPR002197
domain AAA+ ATPase domain 347 - 488 IPR003593
domain PAS fold 204 - 306 IPR013767
binding_site Sigma-54 interaction domain, ATP-binding site 1 351 - 364 IPR025662
binding_site Sigma-54 interaction domain, ATP-binding site 2 410 - 425 IPR025943

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

3 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P38035 rtcR Transcriptional regulatory protein RtcR Escherichia coli (strain K12) PR
10 20 30 40 50 60
MSGAFNNDGR GISPLIATSW ERCNKLMKRE TWNVPHQAQG VTFASIYRRK KAMLTLGQAA
70 80 90 100 110 120
LEDAWEYMAP RECALFILDE TACILSRNGD PQTLQQLSAL GFNDGTYCAE GIIGTCALSL
130 140 150 160 170 180
AAISGQAVKT MADQHFKQVL WNWAFCATPL FDSKGRLTGT IALACPVEQT TAADLPLTLA
190 200 210 220 230 240
IAREVGNLLL TDSLLAETNR HLNQLNALLE SMDDGVISWD EQGNLQFINA QAARVLRLDA
250 260 270 280 290 300
TASQGRAITE LLTLPAVLQQ AIKQAHPLKH VEATFESQHQ FIDAVITLKP IIETQGTSFI
310 320 330 340 350 360
LLLHPVEQMR QLMTSQLGKV SHTFAHMPQD DPQTRRLIHF GRQAARSSFP VLLCGEEGVG
370 380 390 400 410 420
KALLSQAIHN ESERAAGPYI AVNCELYGDA ALAEEFIGGD RTDNENGRLS RLELAHGGTL
430 440 450 460 470 480
FLEKIEYLAV ELQSALLQVI KQGVITRLDA RRLIPIDVKV IATTTADLAM LVEQNRFSRQ
490 500 510 520 530 540
LYYALHAFEI TIPPLRMRRG SIPALVNNKL RSLEKRFSTR LKIDDDALAR LVSCAWPGND
550 560 570 580 590 600
FELYSVIENL ALSSDNGRIR VSDLPEHLFT EQATDDVSAT RLSTSLSFAE VEKEAIINAA
610 620 630
QVTGGRIQEM SALLGIGRTT LWRKMKQHGI DAGQFKRRV