P38035
Gene name |
rtcR (yhgB, b3422, JW3385) |
Protein name |
Transcriptional regulatory protein RtcR |
Names |
|
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b3422 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P38035
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P38035-F1 | Predicted | AlphaFoldDB |
No variants for P38035
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P38035 | |||||
No associated diseases with P38035
5 regional properties for P38035
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PLAT/LH2 domain | 13 - 167 | IPR001024 |
| domain | Lipoxygenase, C-terminal | 169 - 861 | IPR013819 |
| binding_site | Lipoxygenase, iron binding site | 517 - 531 | IPR020833 |
| conserved_site | Lipoxygenase, conserved site | 544 - 554 | IPR020834 |
| domain | Plant lipoxygenase, PLAT/LH2 domain | 13 - 167 | IPR042057 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorelay signal transduction system | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P76016 | dhaR | PTS-dependent dihydroxyacetone kinase operon regulatory protein | Escherichia coli (strain K12) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRKTVAFGFV | GTVLDYAGRG | SQRWSKWRPT | LCLCQQESLV | IDRLELLHDA | RSRSLFETLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDIASVSPET | EVVSVEIELH | NPWDFEEVYA | CLHDFARGYE | FQPEKEDYLI | HITTGTHVAQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ICWFLLAEAR | YLPARLIQSS | PPRKKEQPRG | PGEVTIIDLD | LSRYNAIASR | FAEERQQTLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLKSGIATRN | PHFNRMIEQI | EKVAIKSRAP | ILLNGPTGAG | KSFLARRILE | LKQARHQFSG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AFVEVNCATL | RGDTAMSTLF | GHVKGAFTGA | RESREGLLRS | ANGGMLFLDE | IGELGADEQA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MLLKAIEEKT | FYPFGSDRQV | SSDFQLIAGT | VRDLRQLVAE | GKFREDLYAR | INLWTFTLPG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRQRQEDIEP | NLDYEVERHA | SLTGDSVRFN | TEARRAWLAF | ATSPQATWRG | NFRELSASVT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RMATFATSGR | ITLDVVEDEI | NRLRYNWQES | RPSALTALLG | AEAENIDLFD | RMQLEHVIAI |
| 490 | 500 | 510 | 520 | 530 | |
| CRQAKSLSAA | GRQLFDVSRQ | GKASVNDADR | LRKYLARFGL | TWEAVQDQHS | SS |