P56183
Gene name |
Rrp1 (Nnp1) |
Protein name |
Ribosomal RNA processing protein 1 homolog A |
Names |
Novel nuclear protein 1, NNP-1, Nucleolar protein Nop52, RRP1-like protein |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:18114 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P56183
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P56183-F1 | Predicted | AlphaFoldDB |
35 variants for P56183
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389112316 | 26 | D>N | No | EVA | |
| rs3389108742 | 28 | A>S | No | EVA | |
| rs3389084588 | 84 | H>Y | No | EVA | |
| rs3389076955 | 107 | W>* | No | EVA | |
| rs231000859 | 135 | A>V | No | EVA | |
| rs216911353 | 139 | D>E | No | EVA | |
| rs3401459387 | 159 | S>C | No | EVA | |
| rs3401616357 | 160 | Q>L | No | EVA | |
| rs3401353213 | 162 | P>L | No | EVA | |
| rs3389112334 | 194 | I>N | No | EVA | |
| rs3389111925 | 200 | I>K | No | EVA | |
| rs3389116894 | 201 | A>S | No | EVA | |
| rs3389076952 | 227 | L>F | No | EVA | |
| rs3389121039 | 243 | G>D | No | EVA | |
| rs50258787 | 247 | D>G | No | EVA | |
| rs234256714 | 273 | G>D | No | EVA | |
| rs3389110452 | 274 | D>V | No | EVA | |
| rs3389077014 | 279 | D>E | No | EVA | |
| rs219911366 | 280 | S>G | No | EVA | |
| rs3389112355 | 284 | D>E | No | EVA | |
| rs217385498 | 294 | S>A | No | EVA | |
| rs252375796 | 298 | G>D | No | EVA | |
| rs240543720 | 301 | N>D | No | EVA | |
| rs259568126 | 312 | G>D | No | EVA | |
| rs264978427 | 328 | T>A | No | EVA | |
| rs238177900 | 329 | A>V | No | EVA | |
| rs3389110376 | 331 | R>M | No | EVA | |
| rs217798453 | 337 | D>Y | No | EVA | |
| rs1132279769 | 354 | F>I | No | EVA | |
| rs3389110599 | 361 | N>D | No | EVA | |
| rs3401504043 | 369 | R>I | No | EVA | |
| rs3389116864 | 386 | K>R | No | EVA | |
| rs3389084636 | 403 | K>R | No | EVA | |
| rs3389084590 | 438 | S>C | No | EVA | |
| rs4228303 | 462 | G>E | No | EVA |
No associated diseases with P56183
No regional properties for P56183
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P56183 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
| preribosome, small subunit precursor | A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVPGVPLPPE | IQLAQRLAGN | EQVTRDRALR | KLRKYIEARS | QRATGGFTPD | ELLKVWKGLF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YCMWMQDKPL | QQEELGRTIA | QLVHAFHTTE | AQHQFLKAFW | QTMIREWVGI | DRLRLDKFYM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LMRMVLSESL | KAVKARGWDE | RQIEQLLELL | TTEILNPDSQ | APSGVKSHFL | EIFLEELAKV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GAAELTADQN | LQFIDPFCQI | AARTKDSQVL | HKIIQSIFQT | IVEQAPLAIE | DIMNELDTQS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GEGEASDGDD | GEASDGDDGE | ASDDDDGEAS | DGGDGDVADS | DDSDGADDDD | GDVSDGDGGD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NDEGDSNKSS | EGEQDLQDTP | PKKLPAGTAH | RAGPEADKEQ | AWDDEENAGP | VLQFDYEALA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NRLFKLASRQ | STPSQNRKRL | YKVIQKLREL | AGGTFPEDDV | PEKAYKKMLE | GRRERKKKKK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RLPKPQPQNK | EAGSEAESSS | ADPGPGRKRK | RNRKTDEKAG | QGGPPGKRRK | PGARAKGAGA |
| 490 | |||||
| QQPKKRIQSS | QSAE |