P53303

PR
Gene name
ZPR1 (YGR211W)
Protein name
Zinc finger protein ZPR1
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YGR211W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P53303

Entry ID Method Resolution Chain Position Source
AF-P53303-F1 Predicted AlphaFoldDB

5 variants for P53303

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-915264 7 D>H No SGRP
s07-915343 33 G>D No SGRP
s07-915625 127 T>I No SGRP
s07-915958 238 I>T No SGRP
s07-916525 427 K>M No SGRP

No associated diseases with P53303

2 regional properties for P53303

Type Name Position InterPro Accession
domain Zinc finger, ZPR1-type 52 - 212 IPR004457-1
domain Zinc finger, ZPR1-type 293 - 486 IPR004457-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Translocates to the nucleus after nutrient stimulation
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
G2/M transition of mitotic cell cycle The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
response to glucose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2TBX0 ZNF259 Zinc finger protein ZPR1 Bos taurus (Bovine) PR
O75312 ZPR1 Zinc finger protein ZPR1 Homo sapiens (Human) PR
10 20 30 40 50 60
MSEQKEDLFK PVGEAAAEVE DESIAEQNKA NDGVKLTGAQ DAMGHPVQEI ESLCMNCGKN
70 80 90 100 110 120
GTTRLLLTSI PYFREIIIMS FDCPHCGFKN CEIQPASQIQ EKGSRYVLKV ECREDFNRQV
130 140 150 160 170 180
IKSETATCKF VELDIEIPAK RGQLTTVEGL LSEMIDDLSQ DQEMRKSIDE ALYKKIDDFI
190 200 210 220 230 240
QKVKSYINCE PNTIPITFIL DDPAGNSWIE YKPGEPQHKW SHTQYVRTDE QNVQVGIITR
250 260 270 280 290 300
DQLEQRRQEQ LKQLANRERN PSESVKVGSA NPQFLSDATD IENFNNEVQT FRASCPSCTQ
310 320 330 340 350 360
ECETHMKPVN IPHFKEVIIM STVCDHCGYK SNEVKTGGAI PDKGRRITLY CDDAADLSRD
370 380 390 400 410 420
ILKSETCSMV IPELHLDIQE GTLGGRFTTL EGLLRQVYEE LESRIFTQTS DSMDEATKAR
430 440 450 460 470 480
WVEFFAKLKE AIAGKVKFTV IMEDPLAGSY IQNVYAPDPD PNMTIEDYER TKEQNEDLGL
SDIKVE