P53285
Gene name |
VPS62 (YGR141W) |
Protein name |
Vacuolar protein sorting-associated protein 62 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YGR141W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P53285
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P53285-F1 | Predicted | AlphaFoldDB |
4 variants for P53285
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s07-770797 | 75 | K>R | No | SGRP | |
| s07-770994 | 141 | V>I | No | SGRP | |
| s07-771073 | 167 | G>D | No | SGRP | |
| s07-771285 | 238 | K>E | No | SGRP |
No associated diseases with P53285
No regional properties for P53285
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P53285 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| fungal-type vacuole membrane | The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein targeting to vacuole | The process of directing proteins towards the vacuole, usually using signals contained within the protein. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06466 | TDA6 | Putative vacuolar protein sorting-associated protein TDA6 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRISKNSHKR | QRTRLYFLVT | FIIYSIIPCR | AVLVPWLDDD | PFEATLLEMG | DEPWSKDILS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STPPLHPSEV | TEDNKSLKQR | GNVPQYVIDN | SPLLHLYSEE | KYWPADVKDF | VKRFQLRDHS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GEKIINEHLR | DLSDLQEYYS | VELENGTWGR | VSSEGTYMTS | LDDFDKGPDW | LLGEQPEYGT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GHIKKAPAVL | FVVDKGNGWV | DAFWFYFYPF | NWGPYIMGSG | PWGNHVGDWE | HSLVRFYKGE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PQYLWMSAHG | GGSAYKFEAI | EKIKRLRRVD | GKLTNEVIKK | PLIFSARGTH | AHYASVGQHA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HDVPFFFMPL | SDFTDRGPLW | DPSLNYYAYT | VTVGEKMTPC | GAEETKMGLE | WLSFKGAWGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KQLRPRDPRQ | KWCPFQWKYI | DGPKGPLFKN | MERVSLCQRF | KWWNFWKGCP | ARRYIKRGEG |
| 430 | 440 | 450 | 460 | ||
| LDAEKNDLVG | DNCGILLYNI | RPKWLRSILR | FLTWRGSVCF | IMDYFTG |