AiPD: Autoinhibited Protein Database

Gene name	SAP4 (YGL229C)
Protein name	SIT4-associating protein SAP4
Names
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YGL229C
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

5-84 (Predicted disordered autoinhibitory region) PR

5-84 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-P53036-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s07-66820	47	E>G	No	SGRP
s07-66764	66	F>L	No	SGRP
s07-66712	83	A>G	No	SGRP
s07-66680	94	L>M	No	SGRP
s07-66664	99	D>G	No	SGRP
s07-66659	101	R>C	No	SGRP
s07-66622	113	D>G	No	SGRP
s07-66504	152	M>I	No	SGRP
s07-66310	217	S>T	No	SGRP
s07-66158	268	D>Y	No	SGRP
s07-66126	278	E>D	No	SGRP
s07-65909	351	L>V	No	SGRP
s07-65798	388	E>K	No	SGRP
s07-65725	412	D>G	No	SGRP
s07-65504	486	K>E	No	SGRP
s07-65502	486	K>N	No	SGRP
s07-65498	488	M>V	No	SGRP
s07-65468	498	I>F	No	SGRP
s07-65356	535	Y>F	No	SGRP
s07-65331	543	D>E	No	SGRP
s07-65202	586	F>L	No	SGRP
s07-65104	619	D>G	No	SGRP
s07-65062	633	F>C	No	SGRP
s07-64837	708	P>L	No	SGRP
s07-64633	776	V>D	No	SGRP

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for P53036

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
protein phosphatase binding	Binding to a protein phosphatase.
protein phosphatase regulator activity	Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.

Name	Definition
G1/S transition of mitotic cell cycle	The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
regulation of phosphoprotein phosphatase activity	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P43612	SAP155	SIT4-associating protein SAP155	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
O75170	PPP6R2	Serine/threonine-protein phosphatase 6 regulatory subunit 2	Homo sapiens (Human)	PR