P41735

PR
Gene name
CAT5
Protein name
5-demethoxyubiquinone hydroxylase, mitochondrial
Names
DMQ hydroxylase, Catabolite repression protein 5, Ubiquinone biosynthesis monooxygenase COQ7
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR125C
EC number
1.14.99.60: Miscellaneous
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P41735

Entry ID Method Resolution Chain Position Source
AF-P41735-F1 Predicted AlphaFoldDB

1 variants for P41735

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-559460 91 I>M No SGRP

No associated diseases with P41735

No regional properties for P41735

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P41735

Functions

Description
EC Number 1.14.99.60 Miscellaneous
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extrinsic component of mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

4 GO annotations of molecular function

Name Definition
3-demethoxyubiquinol 3-hydroxylase activity Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O.
metal ion binding Binding to a metal ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

1 GO annotations of biological process

Name Definition
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P97478 Coq7 5-demethoxyubiquinone hydroxylase, mitochondrial Mus musculus (Mouse) PR
10 20 30 40 50 60
MLSRVSVFKP ASRGFSVLSS LKITEHTSAK HTEKPEHAPK CQNLSDAQAA FLDRVIRVDQ
70 80 90 100 110 120
AGELGADYIY AGQYFVLAHR YPHLKPVLKH IWDQEIHHHN TFNNLQLKRR VRPSLLTPLW
130 140 150 160 170 180
KAGAFAMGAG TALISPEAAM ACTEAVETVI GGHYNGQLRN LANQFNLERT DGTKGPSEEI
190 200 210 220 230
KSLTSTIQQF RDDELEHLDT AIKHDSYMAV PYTVITEGIK TICRVAIWSA ERI