P38892

PR
Gene name
CRG1 (YHR209W)
Protein name
Probable S-adenosylmethionine-dependent methyltransferase CRG1
Names
Cantharidin resistance protein 1
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YHR209W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P38892

Entry ID Method Resolution Chain Position Source
AF-P38892-F1 Predicted AlphaFoldDB

3 variants for P38892

Variant ID(s) Position Change Description Diseaes Association Provenance
s08-519609 58 P>L No SGRP
s08-519682 82 E>D No SGRP
s08-519792 119 C>Y No SGRP

No associated diseases with P38892

3 regional properties for P38892

Type Name Position InterPro Accession
domain Protein kinase domain 148 - 410 IPR000719
active_site Serine/threonine-protein kinase, active site 272 - 284 IPR008271
binding_site Protein kinase, ATP binding site 154 - 180 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
S-adenosylmethionine-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

2 GO annotations of biological process

Name Definition
lipid homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
methylation The process in which a methyl group is covalently attached to a molecule.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P32643 TMT1 Trans-aconitate 3-methyltransferase Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
10 20 30 40 50 60
MPKTSYLNKN FESAHYNNVR PSYPLSLVNE IMKFHKGTRK SLVDIGCGTG KATFVVEPYF
70 80 90 100 110 120
KEVIGIDPSS AMLSIAEKET NERRLDKKIR FINAPGEDLS SIRPESVDMV ISAEAIHWCN
130 140 150 160 170 180
LERLFQQVSS ILRSDGTFAF WFYIQPEFVD FPEALNVYYK YGWSKDYMGK YLNDNQREIL
190 200 210 220 230 240
LNYGGEKLRS LLSDRFGDIE VTIYSPSDPN ASTVTAENSQ FLWRAAITLN QFKEFVKSWS
250 260 270 280 290
IYTSWARDNP SKPDIADIFI NELKEICHCE DLNVPLKIEW STFYYLCRKR E