P34560
Gene name |
rmd-1 (T05G5.7) |
Protein name |
Regulator of microtubule dynamics protein 1 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_T05G5.7 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34560
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34560-F1 | Predicted | AlphaFoldDB |
No variants for P34560
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34560 | |||||
No associated diseases with P34560
No regional properties for P34560
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P34560 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| mitotic spindle pole | Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. |
| spindle microtubule | Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| kinase binding | Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. |
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| attachment of mitotic spindle microtubules to kinetochore | The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| mitotic spindle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1JQC5 | RMDN3 | Regulator of microtubule dynamics protein 3 | Bos taurus (Bovine) | PR |
| Q96TC7 | RMDN3 | Regulator of microtubule dynamics protein 3 | Homo sapiens (Human) | PR |
| Q96DB5 | RMDN1 | Regulator of microtubule dynamics protein 1 | Homo sapiens (Human) | PR |
| Q3UJU9 | Rmdn3 | Regulator of microtubule dynamics protein 3 | Mus musculus (Mouse) | PR |
| Q66H15 | Rmdn3 | Regulator of microtubule dynamics protein 3 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESFATSDKL | FESREFVKGL | EELKKRREDG | EMTCDLLWRM | CRFCHELSTT | MSGEQRRKML |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IEGRDYGLEA | MDLDPSSFLA | AKWTAIMFGL | VVDQLPTKEK | INDGGRLKDM | LDKALELDPT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFALLHLRAR | FSYTIANLSW | LERKAASMLY | SEVPKATIDD | ALVDFKAAYN | QNADWIENLL |
| 190 | 200 | 210 | 220 | ||
| FLSKCHLAKK | EKQQAREMLN | KAIVLPAASS | NDAQFVTECK | SLLQKC |