Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P0C884

Entry ID Method Resolution Chain Position Source
AF-P0C884-F1 Predicted AlphaFoldDB

57 variants for P0C884

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_12485082_T_G 12 F>V No 1000Genomes
ENSVATH05621480 20 N>S No 1000Genomes
tmp_2_12485106_A_T 20 N>Y No 1000Genomes
ENSVATH05621481 21 L>F No 1000Genomes
tmp_2_12485116_C_G 23 T>S No 1000Genomes
ENSVATH13462304 65 R>* No 1000Genomes
tmp_2_12485320_C_T 91 T>I No 1000Genomes
tmp_2_12485383_T_C 112 V>A No 1000Genomes
ENSVATH13462315 112 V>L No 1000Genomes
ENSVATH05621489 115 I>V No 1000Genomes
tmp_2_12485453_A_C 135 E>D No 1000Genomes
ENSVATH05621492 135 E>K No 1000Genomes
ENSVATH05621493 146 Q>R No 1000Genomes
ENSVATH00253335 155 R>K No 1000Genomes
ENSVATH14567928 159 R>H No 1000Genomes
tmp_2_12485623_G_C 192 S>T No 1000Genomes
ENSVATH05621495 193 N>Y No 1000Genomes
ENSVATH05621497
ENSVATH13462317
221 S>R No 1000Genomes
tmp_2_12485728_G_A 227 R>Q No 1000Genomes
tmp_2_12485755_GGAA_TGAA,G 236 G>V No 1000Genomes
tmp_2_12485780_T_G 244 S>R No 1000Genomes
tmp_2_12485811_C_T 255 H>Y No 1000Genomes
tmp_2_12485838_G_A 264 D>N No 1000Genomes
ENSVATH00253336 266 T>I No 1000Genomes
ENSVATH13462320 285 A>T No 1000Genomes
ENSVATH14567929 292 C>F No 1000Genomes
ENSVATH00253337 305 T>I No 1000Genomes
tmp_2_12486004_C_A 319 S>* No 1000Genomes
ENSVATH01921708 322 D>Y No 1000Genomes
ENSVATH01921710 350 W>L No 1000Genomes
ENSVATH00253338 350 W>R No 1000Genomes
tmp_2_12486109_A_C 354 D>A No 1000Genomes
tmp_2_12486127_C_T 360 P>L No 1000Genomes
ENSVATH13462321 372 G>A No 1000Genomes
ENSVATH05621507 376 P>Q No 1000Genomes
ENSVATH05621508 381 S>T No 1000Genomes
ENSVATH01921711 381 S>Y No 1000Genomes
ENSVATH00253339 388 V>L No 1000Genomes
ENSVATH05621512 390 R>W No 1000Genomes
ENSVATH05621519 425 N>K No 1000Genomes
tmp_2_12486328_C_T 427 P>L No 1000Genomes
ENSVATH13462335 432 A>P No 1000Genomes
ENSVATH00253340 446 L>F No 1000Genomes
tmp_2_12486420_G_A 458 A>T No 1000Genomes
tmp_2_12486447_G_A 467 D>N No 1000Genomes
tmp_2_12486465_G_A 473 E>K No 1000Genomes
ENSVATH05621522 476 P>Q No 1000Genomes
ENSVATH05621524 511 K>N No 1000Genomes
ENSVATH14567931 517 Y>H No 1000Genomes
tmp_2_12486714_G_A 556 A>T No 1000Genomes
ENSVATH13462338 571 R>I No 1000Genomes
tmp_2_12486765_G_C 573 V>L No 1000Genomes
tmp_2_12486790_C_T 581 T>M No 1000Genomes
ENSVATH01921717 592 G>E No 1000Genomes
ENSVATH05621528 598 R>C No 1000Genomes
ENSVATH13462339 613 L>F No 1000Genomes
ENSVATH13462340 629 P>S No 1000Genomes

No associated diseases with P0C884

No regional properties for P0C884

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P0C884

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SDQ3 SCL1 Scarecrow-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9S7H5 SCL21 Scarecrow-like protein 21 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDPNFSESLN GFEYFDGNPN LLTDPMEDQY PPPSDTLLKY VSEILMEESN GDYKQSMFYD
70 80 90 100 110 120
SLALRKTEEM LQQVITDSQN QSFSPADSLI TNSWDASGSI DESAYSADPQ PVNEIMVKSM
130 140 150 160 170 180
FSDAESALQF KKGVEEASKF LPNSDQWVIN LDIERSERRD SVKEEMGLDQ LRVKKNHERD
190 200 210 220 230 240
FEEVRSSKQF ASNVEDSKVT DMFDKVLLLD GECDPQTLLD SEIQAIRSSK NIGEKGKKKK
250 260 270 280 290 300
KKKSQVVDFR TLLTHCAQAI STGDKTTALE FLLQIRQQSS PLGDAGQRLA HCFANALEAR
310 320 330 340 350 360
LQGSTGPMIQ TYYNALTSSL KDTAADTIRA YRVYLSSSPF VTLMYFFSIW MILDVAKDAP
370 380 390 400 410 420
VLHIVDFGIL YGFQWPMFIQ SISDRKDVPR KLRITGIELP QCGFRPAERI EETGRRLAEY
430 440 450 460 470 480
CKRFNVPFEY KAIASQNWET IRIEDLDIRP NEVLAVNAGL RLKNLQDETG SEENCPRDAV
490 500 510 520 530 540
LKLIRNMNPD VFIHAIVNGS FNAPFFISRF KEAVYHYSAL FDMFDSTLPR DNKERIRFER
550 560 570 580 590 600
EFYGREAMNV IACEEADRVE RPETYRQWQV RMVRAGFKQK TIKPELVELF RGKLKKWRYH
610 620
KDFVVDENSK WLLQGWKGRT LYASSCWVPA