P08057

PR
Gene name
TNNI3
Protein name
Troponin I, cardiac muscle
Names
Cardiac troponin I
Species
Bos taurus (Bovine)
KEGG Pathway
bta:511094
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P08057

Entry ID Method Resolution Chain Position Source
AF-P08057-F1 Predicted AlphaFoldDB

No variants for P08057

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P08057

No associated diseases with P08057

No regional properties for P08057

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P08057

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cardiac myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells.
cardiac Troponin complex A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.

5 GO annotations of molecular function

Name Definition
actin binding Binding to monomeric or multimeric forms of actin, including actin filaments.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase inhibitor activity Binds to and stops, prevents or reduces an ATP hydrolysis activity.
magnesium ion binding Binding to a magnesium (Mg) ion.
troponin C binding Binding to troponin C, the calcium-binding subunit of the troponin complex.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P19429 TNNI3 Troponin I, cardiac muscle Homo sapiens (Human) PR
Q9XUN9 tni-3 Troponin I 3 Caenorhabditis elegans PR
10 20 30 40 50 60
MADRSGGSTA GDTVPAPPPV RRRSSANYRA YATEPHAKKK SKISASRKLQ LKTLMLQIAK
70 80 90 100 110 120
QELEREAEER RGEKGRALST RCQPLELAGL GFAELQDLCR QLHARVDKVD EERYDVEAKV
130 140 150 160 170 180
TKNITEIADL NQKIFDLRGK FKRPTLRRVR ISADAMMQAL LGARAKETLD LRAHLKQVKK
190 200 210
EDTEKENREV GDWRKNIDAL SGMEGRKKKF EG