P02197

PR
Gene name
MB
Protein name
Myoglobin
Names
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:418056
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P02197

Entry ID Method Resolution Chain Position Source
AF-P02197-F1 Predicted AlphaFoldDB

3 variants for P02197

Variant ID(s) Position Change Description Diseaes Association Provenance
rs735946493 14 I>L No Ensembl
rs736750219 18 V>G No Ensembl
rs315204999 30 L>M No Ensembl

No associated diseases with P02197

1 regional properties for P02197

Type Name Position InterPro Accession
domain Globin 3 - 148 IPR000971

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, sarcoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.
oxygen binding Binding to oxygen (O2).
oxygen carrier activity Binding to oxygen and delivering it to an acceptor molecule or a specific location.

4 GO annotations of biological process

Name Definition
enucleate erythrocyte differentiation The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.
heart development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
oxygen transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
response to hypoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P06467 Hbz Hemoglobin subunit zeta Mus musculus (Mouse) PR
G1NJB6 MB Myoglobin Meleagris gallopavo (Wild turkey) PR
10 20 30 40 50 60
MGLSDQEWQQ VLTIWGKVEA DIAGHGHEVL MRLFHDHPET LDRFDKFKGL KTPDQMKGSE
70 80 90 100 110 120
DLKKHGATVL TQLGKILKQK GNHESELKPL AQTHATKHKI PVKYLEFISE VIIKVIAEKH
130 140 150
AADFGADSQA AMKKALELFR NDMASKYKEF GFQG