O95155
PR
Gene name |
UBE4B |
Protein name |
Ubiquitin conjugation factor E4 B |
Names |
Homozygously deleted in neuroblastoma 1, RING-type E3 ubiquitin transferase E4 B, Ubiquitin fusion degradation protein 2 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:10277 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for O95155
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2KRE | NMR | - | A | 1208-1302 | PDB |
| 3L1X | X-ray | 260 A | A | 1208-1302 | PDB |
| 3L1Z | X-ray | 317 A | B | 1208-1302 | PDB |
| 5O75 | X-ray | 148 A | A | 1226-1302 | PDB |
| AF-O95155-F1 | Predicted | AlphaFoldDB |
771 variants for O95155
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA579508 rs753542673 |
5 | S>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 10 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1265980366 CA338687495 |
10 | R>L | No |
ClinGen TOPMed |
|
|
rs761955109 COSM180498 CA579523 |
11 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
| TCGA novel | 16 | R>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA579524 rs767666737 |
19 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs1310653618 CA338687548 |
20 | G>R | No |
ClinGen gnomAD |
|
|
CA579526 rs761207145 |
21 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs773160592 CA18267919 |
21 | Q>R | No |
ClinGen Ensembl |
|
|
rs1415218195 CA338687794 |
23 | S>T | No |
ClinGen gnomAD |
|
|
rs1324626949 CA338687825 |
26 | T>A | No |
ClinGen gnomAD |
|
|
CA579527 rs149396014 |
26 | T>S | No |
ClinGen ESP ExAC |
|
|
CA579528 rs754154046 |
27 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs1570824857 CA338687857 |
30 | T>P | No |
ClinGen Ensembl |
|
|
CA338687872 rs1218690250 |
31 | S>F | No |
ClinGen gnomAD |
|
|
CA338687925 rs1570824880 |
36 | N>T | No |
ClinGen Ensembl |
|
|
rs1212128708 CA338687938 |
37 | P>L | No |
ClinGen gnomAD |
|
|
CA579530 rs764778044 |
37 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA579532 rs757933390 |
38 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752241237 CA579531 |
38 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1477430774 CA338687955 |
39 | G>V | No |
ClinGen gnomAD |
|
|
CA579535 rs757074810 |
39 | G>W | No |
ClinGen ExAC gnomAD |
|
|
CA338687961 rs1361076009 |
40 | P>L | No |
ClinGen TOPMed |
|
|
rs1396567315 CA338687968 |
41 | P>S | No |
ClinGen gnomAD |
|
|
rs768969960 CA579538 |
42 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA579537 rs762612503 |
42 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA338687987 rs1382452772 |
43 | A>E | No |
ClinGen gnomAD |
|
|
rs866841780 CA338687993 |
44 | A>S | No |
ClinGen gnomAD |
|
|
rs866841780 CA18267990 |
44 | A>T | No |
ClinGen gnomAD |
|
|
rs375183552 CA579540 |
46 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579541 rs772292646 |
47 | P>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338688022 rs1288333151 |
47 | P>S | No |
ClinGen TOPMed |
|
|
CA579542 rs201460610 |
48 | G>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA18267999 rs575482388 |
48 | G>R | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs761335727 CA579543 |
49 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338688045 rs1285777734 |
49 | P>L | No |
ClinGen gnomAD |
|
|
CA579544 rs771333173 |
50 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA579545 rs777104550 |
51 | Q>E | No |
ClinGen ExAC |
|
|
CA579546 rs372828525 |
52 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1254275488 CA338688098 |
54 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
CA338688095 rs1191276574 |
54 | G>C | No |
ClinGen gnomAD |
|
|
rs1254275488 CA338688100 |
54 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA579547 rs147996327 |
56 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA338688150 rs1455201082 |
58 | H>Q | No |
ClinGen gnomAD |
|
|
rs1361676211 CA338688147 |
58 | H>R | No |
ClinGen gnomAD |
|
|
rs1284389073 CA338688158 |
59 | N>S | No |
ClinGen Ensembl |
|
|
CA579552 rs757274612 |
60 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs751064668 CA579551 |
60 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA579550 rs376582075 |
60 | M>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs780968429 CA579553 |
61 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA579554 rs369103530 |
62 | P>S | No |
ClinGen ESP ExAC gnomAD |
|
|
CA338688234 rs1334181455 |
65 | S>F | No |
ClinGen gnomAD |
|
|
rs143678952 COSM107955 CA18268048 |
66 | P>L | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
rs556030521 CA579556 |
67 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579557 rs556030521 |
67 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338306055 rs1471186058 |
71 | G>A | No |
ClinGen gnomAD |
|
|
rs147138653 CA579586 |
72 | V>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1453711526 CA338306071 |
73 | A>T | No |
ClinGen gnomAD |
|
|
CA338306092 rs1194429705 |
74 | H>R | No |
ClinGen TOPMed |
|
|
CA579587 rs781272283 |
74 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1394717339 CA338306098 |
75 | R>G | No |
ClinGen TOPMed |
|
|
rs996720320 CA17794845 |
75 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA579589 rs770277863 |
80 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1295680438 CA338306205 |
81 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA338306258 rs1230958597 |
84 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
CA579590 rs775888771 |
87 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1448580510 CA338306314 |
88 | S>A | No |
ClinGen TOPMed |
|
|
CA338306356 rs1316166323 |
91 | N>D | No |
ClinGen gnomAD |
|
|
rs749630439 CA579591 |
95 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA521126463 rs1252391051 |
97 | S>* | No |
ClinGen gnomAD |
|
|
rs796962282 CA17794873 |
97 | S>A | No |
ClinGen Ensembl |
|
|
rs1195688490 CA338306496 |
100 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs761471741 CA579594 |
101 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA338306528 rs1418910074 |
102 | R>C | No |
ClinGen gnomAD |
|
|
CA17794885 rs758468672 |
102 | R>H | No |
ClinGen gnomAD |
|
|
CA17794888 rs986721397 |
106 | M>T | No |
ClinGen TOPMed |
|
|
rs1252567995 CA338306614 |
107 | D>N | No |
ClinGen TOPMed |
|
|
CA579596 rs772776170 |
109 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338306638 rs1266417929 |
110 | G>C | No |
ClinGen gnomAD |
|
|
CA579598 rs766399484 |
113 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs1180802154 CA338306666 |
114 | E>G | No |
ClinGen TOPMed |
|
|
rs747823244 CA579611 |
117 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579612 rs371056737 |
118 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338308509 rs1202632309 |
120 | V>M | No |
ClinGen gnomAD |
|
|
CA579613 rs772650238 |
129 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs890124876 CA338308573 |
129 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
CA17798530 rs890124876 |
129 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA338308591 rs1256108399 |
131 | V>A | No |
ClinGen gnomAD |
|
|
rs1172387586 CA338308613 |
134 | N>S | No |
ClinGen TOPMed |
|
|
rs765951687 CA579615 |
135 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs760809804 COSM1472335 CA579616 COSM176684 |
136 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs759485063 CA579617 |
140 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1014550088 CA17798539 |
140 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA579618 rs374692148 |
141 | S>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1320716836 CA338308668 |
143 | S>G | No |
ClinGen Ensembl |
|
|
rs1397712772 CA338308670 |
143 | S>N | No |
ClinGen TOPMed |
|
| TCGA novel | 145 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs762775537 CA579640 |
147 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1350555110 CA338309035 |
147 | P>H | No |
ClinGen gnomAD |
|
|
rs762775537 CA338309033 |
147 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338309039 rs1201367463 |
148 | S>P | No |
ClinGen gnomAD |
|
|
CA579641 rs763757309 |
149 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17799448 rs368280932 |
150 | G>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA579643 rs368280932 |
150 | G>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA579644 rs139159603 |
151 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1396475092 CA338309092 |
156 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs753903083 CA579645 |
158 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1557554136 CA338309106 |
158 | A>V | No |
ClinGen Ensembl |
|
|
rs372027851 CA579647 |
160 | Q>K | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579648 rs753106906 |
162 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs758817230 CA579649 |
163 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1329700818 CA338309163 |
167 | R>C | No |
ClinGen TOPMed |
|
|
rs777945500 CA579650 |
167 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs746660899 CA338309193 CA579651 |
171 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1333033161 CA338309204 |
173 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA579652 rs770698545 |
173 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17799479 rs981064616 |
174 | D>V | No |
ClinGen TOPMed gnomAD |
|
|
CA17799480 rs902609487 |
177 | V>L | No |
ClinGen Ensembl |
|
|
CA579655 rs376014052 |
182 | S>F | No |
ClinGen ESP ExAC gnomAD |
|
|
rs183958340 CA579656 |
184 | S>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs369303157 CA579657 |
185 | A>P | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1361802523 CA338309295 |
187 | F>L | No |
ClinGen gnomAD |
|
|
rs1180842712 CA338309291 |
187 | F>V | No |
ClinGen gnomAD |
|
|
CA17799497 rs996397895 |
189 | Q>E | No |
ClinGen TOPMed |
|
|
CA338309313 rs1435682166 |
190 | N>D | No |
ClinGen TOPMed |
|
|
CA579660 rs200309857 |
191 | P>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs368654870 CA17799502 |
192 | K>E | No |
ClinGen Ensembl |
|
|
CA338309328 rs1417050614 |
192 | K>R | No |
ClinGen gnomAD |
|
|
CA579661 rs146544433 |
193 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338309332 rs1557554402 |
193 | E>K | No |
ClinGen Ensembl |
|
|
CA338309724 rs765367588 |
196 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17800755 rs765367588 |
196 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579683 rs765367588 |
196 | S>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs377095783 CA579685 |
197 | D>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377095783 CA338309731 |
197 | D>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338309817 rs1226031810 |
203 | G>S | No |
ClinGen gnomAD |
|
|
CA579687 rs752009916 |
207 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1205613284 CA338309887 |
207 | M>T | No |
ClinGen gnomAD |
|
|
CA338309882 rs752009916 |
207 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579688 rs757725666 |
210 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs370526193 CA579689 |
212 | M>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA17800776 rs867051886 |
212 | M>T | No |
ClinGen Ensembl |
|
|
rs1189924817 CA338309951 |
213 | S>P | No |
ClinGen gnomAD |
|
|
CA338309958 rs1179343540 |
214 | T>A | No |
ClinGen gnomAD |
|
|
CA579691 rs755718728 |
217 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA579692 rs779674134 |
218 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579693 rs748727008 |
225 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1169651943 CA338310103 |
226 | T>P | No |
ClinGen gnomAD |
|
|
CA579694 rs754986006 |
228 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA17800809 rs941068670 |
230 | Q>E | No |
ClinGen TOPMed |
|
|
rs1481983038 CA338310170 |
231 | P>A | No |
ClinGen TOPMed |
|
|
rs778855245 CA579695 |
234 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA338310221 rs1190022743 |
235 | A>T | No |
ClinGen TOPMed |
|
|
rs748033324 CA579696 |
235 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA579698 rs772928952 |
237 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579697 rs771871986 |
237 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338310268 rs1366932212 |
238 | S>L | No |
ClinGen gnomAD |
|
|
CA338310274 rs1557557003 |
239 | P>S | No |
ClinGen Ensembl |
|
|
CA579699 rs746164686 |
241 | R>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 243 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA579700 rs145174224 |
244 | L>F | No |
ClinGen ESP ExAC TOPMed |
|
|
rs367582496 CA579702 |
247 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA579704 rs775019058 |
249 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA338310440 rs1204646466 |
251 | P>T | No |
ClinGen gnomAD |
|
|
rs527831194 CA579706 |
252 | G>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1570899058 CA338310471 |
254 | S>G | No |
ClinGen Ensembl |
|
|
CA338310476 rs1182376757 |
254 | S>N | No |
ClinGen gnomAD |
|
|
CA579707 rs750740322 |
255 | P>S | No |
ClinGen ExAC gnomAD |
|
|
COSM1497578 rs760425310 COSM1497577 CA579708 |
256 | M>V | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs939099104 CA17800913 |
257 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA338310539 rs1414831739 |
258 | C>Y | No |
ClinGen TOPMed |
|
|
rs745610889 CA579710 |
259 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA338310565 rs150442851 |
260 | V>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA579711 rs150442851 |
260 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA338310619 rs1435151814 |
264 | G>S | No |
ClinGen gnomAD |
|
|
CA338310622 rs1366169996 |
264 | G>V | No |
ClinGen TOPMed |
|
|
CA338310672 rs1324860297 |
266 | S>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA338310664 rs1324860297 |
266 | S>T | No |
ClinGen gnomAD |
|
|
rs945275338 CA17800940 |
268 | L>F | No |
ClinGen TOPMed |
|
|
CA338310848 rs1163576282 |
270 | S>R | No |
ClinGen gnomAD |
|
|
CA338310860 rs1391842082 |
271 | L>F | No |
ClinGen gnomAD |
|
|
rs1391842082 CA338310858 |
271 | L>V | No |
ClinGen gnomAD |
|
|
rs768868657 CA579720 |
272 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA17801147 rs373071786 |
273 | E>K | No |
ClinGen ESP |
|
|
CA338310926 rs1273592776 |
274 | S>G | No |
ClinGen TOPMed |
|
| TCGA novel | 274 | S>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA579722 rs762476505 |
276 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA579721 rs200980839 |
276 | P>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs773667051 CA579724 |
277 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA17801166 rs1044848007 |
282 | F>L | No |
ClinGen Ensembl |
|
|
rs1443064741 CA338311153 |
283 | W>R | No |
ClinGen TOPMed |
|
|
CA338311194 rs753449921 |
284 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs753449921 CA579727 |
284 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA17801170 rs998210395 |
285 | S>C | No |
ClinGen TOPMed |
|
|
COSM333330 rs41280796 CA579728 |
287 | P>L | lung [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs1223996573 CA338311264 |
287 | P>S | No |
ClinGen gnomAD |
|
|
CA338311289 rs1180455497 |
288 | V>A | No |
ClinGen gnomAD |
|
|
rs1003391370 CA17801183 |
288 | V>M | No |
ClinGen TOPMed |
|
|
CA579731 rs758376675 |
289 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs891835027 CA17801195 |
290 | G>C | No |
ClinGen TOPMed |
|
|
CA17801197 rs199915638 |
290 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579732 rs199915638 |
290 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs199643842 CA579733 |
291 | P>L | Variant assessed as Somatic; 0.0003712 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs1366768691 CA338311399 |
292 | S>A | No |
ClinGen TOPMed |
|
|
rs780981252 CA579735 |
292 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA579736 rs749525437 |
296 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA579738 rs779183499 |
297 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA579739 rs748208469 |
298 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772153110 CA579740 |
298 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579741 rs772153110 |
298 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338311559 rs1570900429 |
306 | P>S | No |
ClinGen Ensembl |
|
|
rs1275368127 CA338311570 |
308 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA579744 rs374971203 |
309 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA338311577 rs1307131638 |
309 | P>S | No |
ClinGen gnomAD |
|
|
rs759248268 CA579745 |
312 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1184294196 CA338311616 |
313 | H>P | No |
ClinGen TOPMed gnomAD |
|
|
rs201579904 CA579746 |
314 | S>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs200554034 CA579747 |
315 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA338311681 rs1172518666 |
317 | S>F | No |
ClinGen gnomAD |
|
|
rs549516957 CA579748 |
318 | G>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs763608761 CA579749 |
319 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA17801256 rs1020230213 |
321 | A>V | No |
ClinGen TOPMed |
|
|
CA579751 rs757149949 |
323 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs368465936 CA579752 |
324 | Q>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579755 rs755292165 |
328 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755292165 CA579754 |
328 | P>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338311844 rs1403632654 |
328 | P>S | No |
ClinGen gnomAD |
|
|
CA579757 rs758423694 |
329 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17801306 rs758423694 |
329 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579758 rs758423694 |
329 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17801293 rs975839657 |
329 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs372819662 CA579759 COSM1231580 |
331 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA579760 COSM893028 rs180983516 |
331 | R>H | endometrium [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed |
|
CA579762 rs746196068 |
334 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA17801353 rs909148687 |
336 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA338311966 rs1343377721 |
336 | T>S | No |
ClinGen gnomAD |
|
|
COSM1720896 rs770101854 CA579763 |
337 | H>Y | NS [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA338312005 rs1290137167 |
338 | P>L | No |
ClinGen TOPMed |
|
|
CA17801363 rs960396416 |
339 | W>* | No |
ClinGen TOPMed |
|
|
rs1210226094 CA338312008 |
339 | W>R | No |
ClinGen gnomAD |
|
|
rs1229151955 CA338312030 |
340 | A>G | No |
ClinGen TOPMed |
|
|
rs201736832 CA579766 |
341 | S>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs371947163 CA579767 |
343 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs767458720 CA579769 |
344 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338312107 rs1570900953 |
347 | L>M | No |
ClinGen Ensembl |
|
|
rs752419508 CA579770 |
348 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338312121 rs1334950644 |
348 | S>P | No |
ClinGen TOPMed gnomAD |
|
|
CA17801365 rs752419508 |
348 | S>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1322873106 CA338312127 |
349 | S>R | No |
ClinGen gnomAD |
|
|
CA17801370 rs979260168 |
351 | P>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 352 | S>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs755996153 CA579772 |
353 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 353 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA579771 rs755996153 |
353 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769331364 CA17801375 |
354 | P>A | No |
ClinGen Ensembl |
|
|
rs752975297 CA579773 |
356 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA338312206 rs1284141946 |
357 | A>D | No |
ClinGen gnomAD |
|
|
rs772803836 CA338312205 |
357 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772803836 CA579775 |
357 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs571542206 CA579776 |
358 | S>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs569201111 CA17801381 |
359 | S>I | No |
ClinGen Ensembl |
|
|
CA579777 rs757748660 |
360 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA338312225 rs1306446208 |
360 | P>S | No |
ClinGen TOPMed |
|
|
rs1248326290 CA338312232 |
361 | Q>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA338312238 rs1315234603 |
362 | A>P | No |
ClinGen TOPMed |
|
|
COSM1332023 CA579779 rs746328640 |
365 | A>T | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs770159407 CA579780 |
365 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1157977899 CA338312259 |
366 | S>G | No |
ClinGen gnomAD |
|
|
rs1409644352 CA338312278 |
368 | S>C | No |
ClinGen gnomAD |
|
|
CA338312277 rs1409644352 |
368 | S>Y | No |
ClinGen gnomAD |
|
|
rs1266275834 CA338312282 |
369 | R>K | No |
ClinGen TOPMed |
|
|
rs1263339779 CA338312291 |
370 | Q>R | No |
ClinGen gnomAD |
|
|
COSM462481 CA579782 rs375249164 |
371 | R>K | kidney Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs369581649 CA579783 |
371 | R>S | No |
ClinGen ESP ExAC |
|
|
rs539367551 CA579781 |
371 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 372 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338312343 rs1389681861 |
374 | S>I | No |
ClinGen gnomAD |
|
|
rs773782785 CA579784 |
375 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579786 rs536600344 |
376 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1437601166 CA338312377 |
377 | P>S | No |
ClinGen gnomAD |
|
|
CA579788 rs547751822 |
380 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1188169792 CA338312450 |
382 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
COSM1332024 rs548707778 CA579792 |
382 | A>T | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA579793 rs751695840 |
383 | S>L | No |
ClinGen ExAC gnomAD |
|
|
CA579794 rs757383030 |
384 | P>A | No |
ClinGen ExAC gnomAD |
|
|
COSM326804 rs1367587731 CA338312476 |
384 | P>L | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA338312469 rs757383030 |
384 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA338312488 rs1479959631 |
385 | S>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1479959631 CA338312490 |
385 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
CA579796 rs371276917 |
386 | A>G | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579797 rs371276917 |
386 | A>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs780456251 CA579799 |
387 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs1184471236 CA338312514 |
387 | T>S | No |
ClinGen gnomAD |
|
|
rs1457446119 CA338312545 |
389 | R>K | No |
ClinGen gnomAD |
|
|
rs749641898 CA579800 |
390 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs768862044 CA579801 |
390 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs1557558553 CA338312601 |
393 | S>Y | No |
ClinGen Ensembl |
|
|
rs374799748 CA579803 |
394 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338312633 rs369759551 |
396 | I>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579804 rs369759551 |
396 | I>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772841228 CA338312653 |
397 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772841228 CA579805 |
397 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs575934269 CA579840 |
402 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA338316857 rs1331531405 |
404 | G>S | No |
ClinGen gnomAD |
|
|
CA579841 rs765689091 |
405 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs752979773 CA579842 |
405 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA338316915 rs1193278015 |
407 | S>T | No |
ClinGen gnomAD |
|
|
CA579843 rs372287496 |
408 | N>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579844 rs777596249 |
412 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs898101568 CA17806482 |
412 | Y>H | No |
ClinGen TOPMed gnomAD |
|
|
CA338317103 rs1457281098 |
415 | H>Y | No |
ClinGen gnomAD |
|
|
rs1163695672 CA338317212 |
418 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA579846 rs756845127 |
420 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA579847 rs780504581 |
424 | T>R | No |
ClinGen ExAC gnomAD |
|
|
CA579848 rs745887037 |
425 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA338317467 rs1407878978 |
426 | M>R | No |
ClinGen TOPMed gnomAD |
|
|
CA338317474 rs1407878978 |
426 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1290108208 CA338317541 |
429 | Y>C | No |
ClinGen gnomAD |
|
|
CA579850 rs775406556 |
430 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs993664560 CA17806513 |
431 | I>V | No |
ClinGen Ensembl |
|
|
rs1478451598 CA338317596 |
432 | E>K | No |
ClinGen TOPMed |
|
|
CA338317628 rs768400495 |
433 | C>G | No |
ClinGen ExAC gnomAD |
|
|
rs768400495 CA579852 |
433 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs1336891073 CA338317655 |
435 | D>Y | No |
ClinGen TOPMed |
|
|
CA338317680 rs1435841467 |
436 | R>Q | No |
ClinGen gnomAD |
|
|
CA338317710 rs1320070477 |
438 | G>* | No |
ClinGen gnomAD |
|
|
CA579854 rs760819326 |
438 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338317733 rs1292896031 |
439 | I>K | No |
ClinGen gnomAD |
|
|
rs1483031638 CA338317745 |
440 | E>K | No |
ClinGen gnomAD |
|
|
CA579856 rs143511579 COSM1269641 COSM1269642 |
441 | E>G | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA338317779 rs1557569244 |
441 | E>K | No |
ClinGen Ensembl |
|
|
rs1470251095 CA338317831 |
443 | K>R | No |
ClinGen gnomAD |
|
| rs758215455 | 444 | A>H | Variant assessed as Somatic; 4.901e-05 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776558973 CA579857 |
444 | A>T | No |
ClinGen ExAC |
|
|
rs983877167 CA17806553 |
446 | K>E | No |
ClinGen gnomAD |
|
|
rs1420153679 CA338318028 |
447 | M>T | No |
ClinGen gnomAD |
|
|
rs1448847933 CA338318026 |
447 | M>V | No |
ClinGen TOPMed |
|
|
CA17807752 rs922947993 |
448 | C>W | No |
ClinGen Ensembl |
|
|
CA579878 rs138638392 |
449 | S>G | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579879 rs371698194 |
450 | Q>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579881 rs776157937 |
456 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA579882 rs148471735 |
460 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs751961761 CA579884 |
461 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA579885 rs761577852 |
461 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs761577852 CA579886 |
461 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA579888 rs755602888 |
463 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA338318142 rs1164931637 |
464 | C>F | No |
ClinGen Ensembl |
|
|
rs1219200976 CA338318160 |
467 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1313503255 CA338318170 |
468 | T>I | No |
ClinGen gnomAD |
|
|
CA579889 rs779472115 |
468 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs753839442 CA579890 |
469 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA17807852 rs917921765 |
473 | Q>P | No |
ClinGen gnomAD |
|
|
rs917921765 CA17807858 |
473 | Q>R | No |
ClinGen gnomAD |
|
|
CA579894 rs771856770 |
478 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA338318308 rs1317155363 |
479 | P>L | No |
ClinGen TOPMed |
|
|
rs1406043582 CA338319378 |
481 | S>F | No |
ClinGen gnomAD |
|
|
rs1281607603 CA338319437 |
482 | L>F | No |
ClinGen TOPMed |
|
|
rs1169056154 CA338319456 |
483 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
CA338319448 rs1169056154 |
483 | Q>K | No |
ClinGen TOPMed gnomAD |
|
|
CA338319459 rs149760840 |
483 | Q>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579914 rs149760840 |
483 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579915 rs756393620 |
485 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA17808889 rs868860717 |
485 | P>S | No |
ClinGen Ensembl |
|
|
CA579917 rs749349715 |
490 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs780332508 CA579916 |
490 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA338319697 rs1490443808 |
492 | M>V | No |
ClinGen gnomAD |
|
|
CA338319770 rs1204411594 |
495 | R>G | No |
ClinGen gnomAD |
|
|
rs1490043437 CA338319957 |
500 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA338320014 rs1471691473 |
502 | I>L | No |
ClinGen gnomAD |
|
|
rs1184000477 CA338320063 |
503 | Q>L | No |
ClinGen gnomAD |
|
|
CA338320268 rs1472686637 |
511 | Q>* | No |
ClinGen TOPMed |
|
|
rs1364616583 CA338320294 |
512 | D>N | No |
ClinGen gnomAD |
|
|
CA579939 rs755122750 |
519 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA579940 rs370043403 |
520 | F>C | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579941 rs748661352 |
522 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA579942 rs375335781 |
523 | I>M | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579943 rs367994851 |
524 | L>* | No |
ClinGen ESP ExAC gnomAD |
|
|
CA579944 rs567295259 |
525 | Q>R | No |
ClinGen 1000Genomes ExAC |
|
|
rs143784553 CA17815040 |
532 | K>I | No |
ClinGen ESP gnomAD |
|
|
CA338322275 rs143784553 |
532 | K>R | No |
ClinGen ESP gnomAD |
|
| TCGA novel | 532 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA579946 rs776275736 |
534 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs764797641 CA579948 |
537 | D>A | No |
ClinGen ExAC gnomAD |
|
|
CA579947 rs373796395 |
537 | D>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA579949 rs376349016 |
538 | S>N | No |
ClinGen ESP ExAC gnomAD |
|
|
CA338322377 rs1201832847 |
540 | Y>S | No |
ClinGen TOPMed |
|
|
CA338322407 rs1245203502 |
542 | K>T | No |
ClinGen gnomAD |
|
|
CA579951 rs764065405 |
544 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA338322432 rs1188352432 |
544 | P>R | No |
ClinGen gnomAD |
|
|
CA338322430 rs764065405 |
544 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs754118135 CA579955 |
545 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA579956 rs755237157 |
545 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs777644646 CA579977 |
547 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1216982603 CA338322567 |
548 | L>R | No |
ClinGen gnomAD |
|
|
CA338322564 rs1318897112 |
548 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
CA579978 rs752124501 |
549 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs752124501 CA338322572 |
549 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA579980 rs781588366 |
561 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs1482482521 CA338323667 |
561 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs746204283 CA579981 |
564 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA580013 rs774520660 |
566 | V>A | No |
ClinGen ExAC gnomAD |
|
|
COSM1332043 CA580017 rs541907403 COSM1332042 |
570 | R>Q | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs142704128 CA580015 |
570 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs61760196 CA580018 |
571 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs754119546 CA580019 |
574 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA580020 rs755327612 |
576 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1243402312 CA338324419 |
581 | C>R | No |
ClinGen TOPMed |
|
|
CA580021 rs200546136 |
583 | R>Q | No |
ClinGen 1000Genomes ExAC |
|
| TCGA novel | 584 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs747743981 CA580022 |
587 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA338324630 rs1175733084 |
587 | R>T | No |
ClinGen gnomAD |
|
|
rs776532939 CA580027 |
593 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs373123755 CA17817734 |
594 | F>L | No |
ClinGen ESP gnomAD |
|
|
CA338324914 rs1363199002 |
595 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
VAR_052437 CA580046 rs17034499 |
605 | V>I | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA17817897 rs906687718 |
610 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA580047 rs779820380 |
611 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA338325376 rs779820380 |
611 | Y>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 613 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338325414 rs1270944723 |
613 | S>P | No |
ClinGen gnomAD |
|
|
rs748429885 CA580048 |
614 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs772260738 CA580049 |
614 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA338325466 rs1468758524 |
616 | A>T | No |
ClinGen gnomAD |
|
|
CA338325493 rs374640200 |
617 | I>L | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA17817922 rs374640200 |
617 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
| TCGA novel | 621 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs777007475 CA580053 |
623 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580054 rs760112995 |
623 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580056 rs200835267 |
626 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1279750341 CA338325785 |
629 | L>M | No |
ClinGen gnomAD |
|
|
rs866924603 CA17818035 |
636 | G>R | No |
ClinGen gnomAD |
|
|
rs1249527362 CA338326994 |
638 | Q>* | No |
ClinGen gnomAD |
|
|
rs1337605952 CA338327119 |
642 | K>Q | No |
ClinGen gnomAD |
|
|
rs1197555324 CA338327269 |
646 | S>N | No |
ClinGen gnomAD |
|
|
CA338327375 rs1448017336 |
651 | G>C | No |
ClinGen TOPMed |
|
| TCGA novel | 652 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338327430 rs1557582877 |
654 | R>C | No |
ClinGen Ensembl |
|
|
rs1245402151 CA338327431 |
654 | R>H | No |
ClinGen gnomAD |
|
|
CA338327484 rs1445597981 |
656 | A>T | No |
ClinGen gnomAD |
|
|
CA580074 rs746423754 |
657 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 658 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 659 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580076 rs776102839 |
662 | A>E | No |
ClinGen ExAC gnomAD |
|
|
rs776102839 CA580077 |
662 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs766800561 CA17819360 |
663 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA338327627 rs950908669 |
664 | V>F | No |
ClinGen gnomAD |
|
|
CA17819365 rs950908669 |
664 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
COSM180514 rs140051271 CA580079 |
665 | V>I | large_intestine [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1406616128 CA338327658 |
666 | N>S | No |
ClinGen gnomAD |
|
|
CA17819380 rs982489028 |
668 | N>H | No |
ClinGen Ensembl |
|
| TCGA novel | 668 | N>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338327713 rs1381432709 |
669 | M>K | No |
ClinGen gnomAD |
|
|
rs1357461969 CA338327709 |
669 | M>V | No |
ClinGen gnomAD |
|
|
rs766995114 CA580081 |
672 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 673 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 676 | T>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756270935 CA580110 |
676 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs199753032 CA17821437 |
678 | D>G | No |
ClinGen Ensembl |
|
|
rs1334623481 CA338329111 |
680 | L>S | No |
ClinGen TOPMed |
|
|
rs1304982545 CA338329163 |
682 | S>C | No |
ClinGen gnomAD |
|
|
rs150774269 CA580113 |
687 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1319175278 CA338329749 |
702 | K>R | No |
ClinGen gnomAD |
|
|
rs919140231 CA17821495 |
705 | T>I | No |
ClinGen TOPMed |
|
|
CA580117 rs772854315 |
708 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338329942 rs772854315 |
708 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580119 rs370876093 |
709 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338329957 rs1557585349 |
709 | T>S | No |
ClinGen Ensembl |
|
| TCGA novel | 710 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1175182172 CA338329996 |
711 | I>V | No |
ClinGen gnomAD |
|
|
CA580122 rs765248938 |
714 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA580123 rs752526141 |
715 | R>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA580124 rs762822879 |
717 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1426516833 CA338330102 |
720 | L>I | No |
ClinGen gnomAD |
|
|
rs1164105697 CA338330115 |
721 | P>S | No |
ClinGen gnomAD |
|
|
CA580125 RCV000958811 rs138056371 |
722 | N>S | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1461540113 CA338330216 |
725 | T>M | No |
ClinGen gnomAD |
|
|
CA580127 rs756395634 |
726 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780330455 CA580128 |
726 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1355134346 CA338330278 |
728 | N>S | No |
ClinGen TOPMed |
|
|
CA17821577 rs147799328 |
730 | T>A | No |
ClinGen ESP TOPMed |
|
|
CA580129 rs753923979 |
730 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 732 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338330428 rs1570955194 |
734 | V>M | No |
ClinGen Ensembl |
|
|
rs1324035208 CA338330473 |
736 | D>Y | No |
ClinGen gnomAD |
|
|
rs772492315 CA580133 |
740 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338331066 rs1210485399 |
742 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1188166848 CA338331121 |
746 | P>R | No |
ClinGen gnomAD |
|
|
rs564326522 CA580152 |
751 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1174517541 CA338331216 |
754 | P>S | No |
ClinGen Ensembl |
|
| TCGA novel | 755 | T>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580155 rs780909483 |
755 | T>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 757 | C>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580158 rs774852956 |
758 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs749292041 CA580159 |
763 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs1280988975 CA338331347 |
764 | A>T | No |
ClinGen gnomAD |
|
|
CA580161 rs774391546 |
767 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs761724316 CA580162 |
769 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs767351956 CA580163 |
771 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA580164 rs776977489 |
772 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs988927151 CA17823189 |
772 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 772 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs759661609 CA580165 |
773 | C>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765404233 CA580166 COSM1185305 COSM1185306 |
774 | R>C | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA580167 rs765404233 |
774 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs546373910 CA580168 |
774 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs764605475 CA580169 |
775 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 775 | R>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580171 rs757625036 |
778 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3801066 rs781407095 COSM3801065 CA580172 |
778 | R>H | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA580174 rs755700547 |
781 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580173 rs144897486 |
781 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1570959496 CA338331621 |
783 | I>M | No |
ClinGen Ensembl |
|
|
CA580175 rs565863201 |
783 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs377196706 CA17823274 |
784 | R>Q | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs141750784 CA580176 |
784 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA580177 rs369929304 |
787 | N>S | No |
ClinGen ESP ExAC gnomAD |
|
|
CA338333504 rs1272589452 |
791 | E>Q | No |
ClinGen gnomAD |
|
|
CA580201 rs777726502 |
794 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338333549 rs1436247864 |
794 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs746801529 CA580202 |
796 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA338333572 rs1239218510 |
796 | N>T | No |
ClinGen TOPMed gnomAD |
|
|
CA17828683 rs78150027 |
798 | S>G | No |
ClinGen Ensembl |
|
| TCGA novel | 800 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580203 rs376007292 |
801 | K>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1177145651 CA338333649 |
801 | K>R | No |
ClinGen gnomAD |
|
| TCGA novel | 802 | D>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338333687 rs1433269361 |
804 | P>L | No |
ClinGen TOPMed |
|
|
rs775692397 CA580204 |
804 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1174694276 CA338333689 |
805 | L>V | No |
ClinGen TOPMed |
|
| TCGA novel | 806 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580205 rs763160034 |
807 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs768783317 CA580206 |
808 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs1393919994 CA338333712 |
809 | H>Y | No |
ClinGen gnomAD |
|
|
rs774392667 CA580207 |
810 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580208 rs762423683 |
810 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1450102967 CA338333724 COSM893055 COSM893054 |
811 | E>K | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA338333738 rs1387712717 |
812 | M>I | No |
ClinGen TOPMed |
|
|
rs750897247 CA580210 COSM423327 COSM423326 |
815 | R>C | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs760964695 CA580211 |
815 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766702266 CA580212 |
816 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA17828742 rs777906682 |
816 | C>R | No |
ClinGen Ensembl |
|
|
rs753600433 CA580213 |
818 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA17830022 rs765005672 |
822 | K>R | No |
ClinGen Ensembl |
|
| TCGA novel | 823 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580229 rs773600728 |
824 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs761228558 CA580230 |
825 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA338335005 rs1323039408 |
825 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1453171433 CA338335020 |
826 | C>Y | No |
ClinGen TOPMed |
|
|
CA338335128 rs1205119496 |
831 | D>G | No |
ClinGen gnomAD |
|
|
rs759935288 CA580233 |
836 | D>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752336416 CA580235 |
837 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA580237 rs763653818 |
844 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580240 rs781006256 |
856 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM180522 CA580241 rs148514322 |
856 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs148514322 CA580242 |
856 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338335658 rs1238567744 |
859 | D>V | No |
ClinGen TOPMed |
|
|
rs779124753 CA580243 |
860 | P>S | No |
ClinGen ExAC |
|
|
rs779124753 CA17830079 |
860 | P>T | No |
ClinGen ExAC |
|
|
rs147329205 COSM674705 CA580245 COSM674706 |
861 | A>T | lung kidney Variant assessed as Somatic; 0.0 impact. prostate [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA338335734 rs1332109951 |
863 | P>L | No |
ClinGen gnomAD |
|
|
CA338335746 rs1356416013 |
864 | D>G | No |
ClinGen gnomAD |
|
|
CA580247 rs747506937 |
864 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA580248 rs747506937 |
864 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1480085038 CA338335974 |
865 | I>V | No |
ClinGen gnomAD |
|
| TCGA novel | 870 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1440066323 CA338336107 |
872 | D>E | No |
ClinGen gnomAD |
|
|
CA338336122 rs1182985715 |
873 | V>A | No |
ClinGen gnomAD |
|
|
CA580268 rs777281743 |
875 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA17831571 rs1025826717 |
876 | V>G | No |
ClinGen Ensembl |
|
|
CA580270 rs770338844 |
879 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs762555563 CA580273 |
880 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA338336270 rs1312775556 |
881 | P>S | No |
ClinGen TOPMed |
|
|
rs1402990661 CA338336362 |
885 | V>I | No |
ClinGen gnomAD |
|
|
rs1402990661 CA338336356 |
885 | V>L | No |
ClinGen gnomAD |
|
|
CA580274 rs773827691 |
889 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1377561774 CA338336523 |
892 | L>F | No |
ClinGen gnomAD |
|
|
CA338336528 rs1210480518 |
893 | F>L | No |
ClinGen TOPMed |
|
|
CA580275 rs761330124 |
896 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1050906858 CA17832486 |
901 | Q>H | No |
ClinGen TOPMed |
|
|
rs201222800 CA580289 |
901 | Q>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA338337664 rs201222800 |
901 | Q>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 902 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580290 rs200375353 |
902 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs761454523 CA580292 |
906 | P>S | No |
ClinGen ExAC gnomAD |
|
|
TCGA novel rs1241379901 CA338337749 |
913 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen gnomAD NCI-TCGA |
|
CA580293 rs771630942 |
915 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs771630942 CA580294 |
915 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs1191534489 CA338337763 |
916 | V>I | No |
ClinGen gnomAD |
|
|
CA580295 rs760134669 |
918 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1570987183 CA338337810 |
922 | Q>R | No |
ClinGen Ensembl |
|
|
rs1478295055 CA338337816 |
923 | N>D | No |
ClinGen gnomAD |
|
|
rs1423580634 CA338337839 |
926 | R>Q | No |
ClinGen gnomAD |
|
|
CA17832507 rs914491325 |
928 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
rs914491325 CA338337851 |
928 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA338337886 rs1177437032 |
933 | K>R | No |
ClinGen gnomAD |
|
|
CA580298 rs759379212 |
937 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 940 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764937209 CA580299 |
943 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA338337979 rs751886108 |
945 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751886108 CA580300 |
945 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338337989 rs1570987305 |
946 | Q>E | No |
ClinGen Ensembl |
|
|
CA17832525 rs140232669 |
948 | R>Q | No |
ClinGen ESP TOPMed |
|
|
COSM1332056 CA338338102 COSM1332057 rs1437013074 |
952 | F>L | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA580304 rs750564902 |
960 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580305 rs531190869 |
961 | L>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs375956063 CA338338327 |
964 | K>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 966 | L>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338338354 rs1365239973 |
967 | V>I | No |
ClinGen TOPMed |
|
|
rs1192091400 CA338338415 |
972 | K>R | No |
ClinGen gnomAD |
|
| TCGA novel | 978 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338310861 rs1381410939 |
991 | T>K | No |
ClinGen gnomAD |
|
|
CA580324 rs766368360 |
999 | I>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 1000 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754431540 CA580325 |
1006 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1330254020 CA338311204 |
1007 | I>V | No |
ClinGen gnomAD |
|
|
rs755420565 CA580326 |
1008 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580327 rs779293010 |
1009 | H>L | No |
ClinGen ExAC gnomAD |
|
|
CA338311268 rs1339758357 |
1010 | H>R | No |
ClinGen gnomAD |
|
|
CA338311285 rs748532186 |
1011 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748532186 CA580328 |
1011 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1389705660 CA338311350 |
1015 | E>K | No |
ClinGen TOPMed |
|
|
CA17807554 rs917907372 |
1018 | N>S | No |
ClinGen gnomAD |
|
|
rs1442510858 CA338311610 |
1019 | S>A | No |
ClinGen gnomAD |
|
|
CA580351 rs778096765 |
1021 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA580352 rs746724659 |
1025 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA338311685 rs1464581894 |
1025 | R>L | No |
ClinGen TOPMed |
|
| TCGA novel | 1033 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs866070652 CA17809490 |
1034 | T>K | No |
ClinGen Ensembl |
|
|
rs780856519 CA580354 |
1038 | L>V | No |
ClinGen ExAC |
|
|
rs1402759807 CA338311837 |
1039 | D>N | No |
ClinGen gnomAD |
|
|
rs768633616 CA580359 |
1047 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 1049 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338311969 rs1347765504 |
1051 | V>A | No |
ClinGen TOPMed |
|
|
CA338311963 rs1296558041 |
1051 | V>M | No |
ClinGen gnomAD |
|
|
CA580360 rs773999476 |
1054 | E>G | No |
ClinGen ExAC |
|
|
rs556033322 CA17809554 |
1055 | M>V | No |
ClinGen 1000Genomes |
|
| TCGA novel | 1057 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338312065 rs1330890275 |
1058 | K>R | No |
ClinGen gnomAD |
|
|
rs377001392 CA580361 |
1059 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs768246347 CA17809564 |
1060 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
rs771093729 CA580363 CA580362 |
1063 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs753259261 CA580366 |
1066 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs371058351 CA580365 COSM462486 COSM462485 |
1066 | R>W | kidney Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
CA338313618 rs1295495448 |
1072 | R>C | No |
ClinGen gnomAD |
|
|
rs762089422 CA580387 |
1072 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1337175735 CA338313625 |
1073 | Q>R | No |
ClinGen gnomAD |
|
|
CA580388 rs767921206 |
1074 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs147961171 CA580389 |
1075 | Q>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA338313639 rs1379704266 |
1075 | Q>L | No |
ClinGen gnomAD |
|
| TCGA novel | 1077 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338313658 rs1298952742 |
1078 | Q>L | No |
ClinGen TOPMed |
|
| TCGA novel | 1078 | Q>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580391 rs779753357 |
1081 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779753357 CA338313681 |
1081 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1246619063 CA338313682 |
1082 | V>L | No |
ClinGen gnomAD |
|
|
rs753434706 CA580392 |
1083 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA580393 rs754492212 |
1084 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA580394 rs778716631 |
1084 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs748108497 CA580395 |
1085 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1181189771 COSM1497558 CA338313717 COSM1497559 |
1088 | A>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1181189771 CA338313718 |
1088 | A>T | No |
ClinGen gnomAD |
|
|
CA338313753 rs1202074678 |
1094 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA580400 rs775639481 |
1096 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA580401 rs749385011 |
1099 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs774789457 CA580403 |
1103 | Q>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580404 rs774789457 |
1103 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1302772316 CA338313823 |
1104 | V>I | No |
ClinGen gnomAD |
|
|
CA338313833 rs1397210373 |
1105 | Q>R | No |
ClinGen gnomAD |
|
|
rs1339402125 CA338313860 |
1109 | L>F | No |
ClinGen gnomAD |
|
|
CA17815683 rs973250236 |
1111 | P>L | No |
ClinGen gnomAD |
|
|
COSM1560156 CA338315102 rs1478970742 COSM1560157 |
1116 | R>* | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA338315137 rs1299139816 |
1119 | A>G | No |
ClinGen gnomAD |
|
|
CA338315135 rs1191645442 |
1119 | A>T | No |
ClinGen TOPMed |
|
|
CA338315144 rs1466851312 |
1120 | M>V | No |
ClinGen gnomAD |
|
|
CA580425 rs761137792 |
1128 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA580426 rs1801442 |
1134 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA17818172 rs1801442 |
1134 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17818182 rs201844344 |
1134 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA338315444 rs1400832784 |
1135 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
CA17818185 rs776476371 CA580427 |
1140 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764690277 CA580429 |
1142 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA17818193 rs906670644 |
1145 | G>R | No |
ClinGen Ensembl |
|
|
rs1174804105 CA338316004 |
1151 | L>M | No |
ClinGen gnomAD |
|
|
CA17818235 rs945483903 |
1154 | Q>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1278593832 CA338316326 |
1161 | Q>H | No |
ClinGen gnomAD |
|
|
CA17818271 rs1011230836 |
1165 | A>S | No |
ClinGen Ensembl |
|
|
CA338316401 rs1435267736 |
1166 | R>Q | No |
ClinGen gnomAD |
|
|
rs757111718 CA338316431 |
1167 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA17818282 rs371129617 |
1168 | A>V | No |
ClinGen ESP TOPMed gnomAD |
|
| TCGA novel | 1170 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1557622523 | 1177 | S>* | No | Ensembl | |
|
rs1237918283 CA338318796 |
1179 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1237918283 CA338318797 |
1179 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1456860326 CA338318818 |
1181 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs1184581322 CA338318845 |
1185 | E>* | No |
ClinGen gnomAD |
|
|
CA580455 rs779212741 |
1187 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA338318858 rs1472139001 |
1187 | I>V | No |
ClinGen gnomAD |
|
| TCGA novel | 1188 | S>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 1190 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1188510591 CA338318888 |
1191 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA338318887 rs1419508654 |
1191 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA338318895 rs1388831889 |
1192 | K>R | No |
ClinGen TOPMed |
|
| TCGA novel | 1194 | G>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758559091 CA580457 |
1198 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA338318940 COSM1497552 rs1411650159 COSM1497553 |
1199 | I>T | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA580459 rs759888990 |
1199 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs923293413 CA17826209 |
1201 | I>T | No |
ClinGen Ensembl |
|
|
rs746256550 CA580462 |
1201 | I>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 1202 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580465 rs762500508 |
1208 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762500508 CA580466 |
1208 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA17826279 COSM1686973 COSM1686974 rs145582816 |
1209 | E>K | skin [Cosmic] | No |
ClinGen cosmic curated ESP TOPMed gnomAD |
|
CA580468 rs761275193 |
1211 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580469 rs767467963 |
1213 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA338319035 rs1557622724 |
1213 | E>D | No |
ClinGen Ensembl |
|
|
rs374628108 CA580471 |
1216 | A>T | No |
ClinGen ESP ExAC gnomAD |
|
|
CA338319068 rs143854107 |
1218 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs562708221 CA580473 |
1219 | A>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA580474 rs143909066 |
1219 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA17826333 rs754186357 |
1220 | R>C | No |
ClinGen gnomAD |
|
|
rs764368845 CA580475 |
1220 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757353202 CA580477 |
1221 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs781724601 CA580478 |
1223 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs756559591 CA580480 |
1224 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA338319123 rs1277727339 |
1226 | S>G | No |
ClinGen gnomAD |
|
|
CA17826355 rs1020916816 |
1227 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1271316749 CA338319156 |
1228 | A>T | No |
ClinGen gnomAD |
|
|
CA17826900 rs780161718 |
1239 | T>N | No |
ClinGen Ensembl |
|
|
CA580508 rs770793491 |
1240 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1288840633 CA338319554 |
1243 | D>E | No |
ClinGen gnomAD |
|
|
CA338319586 rs1287279388 |
1244 | P>R | No |
ClinGen TOPMed |
|
|
CA580511 rs765118779 |
1245 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1264482027 CA338319608 |
1246 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs774771590 CA580512 |
1247 | L>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 1249 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338319724 rs1457279187 |
1252 | I>N | No |
ClinGen gnomAD |
|
|
rs1321034789 CA338319793 |
1254 | D>E | No |
ClinGen TOPMed |
|
|
rs767677267 CA580514 COSM180527 |
1255 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs144332718 CA580515 |
1257 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 1259 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA338319911 rs1484052240 |
1259 | L>R | No |
ClinGen TOPMed |
|
|
CA17826963 rs1035052912 |
1260 | R>L | No |
ClinGen Ensembl |
|
| TCGA novel | 1260 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1571047835 CA338319935 |
1261 | H>P | No |
ClinGen Ensembl |
|
|
rs146686475 CA580516 |
1266 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA338320052 rs1413198234 |
1266 | P>L | No |
ClinGen TOPMed |
|
|
rs146686475 CA338320042 |
1266 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs766812302 CA580517 |
1267 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA17827013 rs15191 |
1269 | P>T | No |
ClinGen Ensembl |
|
| TCGA novel | 1270 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1231577 rs758014435 COSM1231576 CA580522 |
1274 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 1275 | L>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs746513099 CA580524 |
1276 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA580525 rs770405723 |
1276 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 1277 | E>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA580550 rs768438112 |
1283 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs773361650 CA580551 |
1284 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA338320697 rs1258464548 |
1288 | E>A | No |
ClinGen gnomAD |
|
|
CA338320702 rs1485770254 |
1288 | E>D | No |
ClinGen gnomAD |
|
|
CA580552 rs760943458 |
1289 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1456468035 CA338320747 |
1291 | Q>L | No |
ClinGen TOPMed |
|
|
CA580553 rs771034338 |
1292 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA580555 rs759576338 |
1294 | M>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1173487668 CA338320825 |
1294 | M>V | No |
ClinGen gnomAD |
|
|
rs1407219381 CA338320857 |
1295 | R>T | No |
ClinGen TOPMed |
|
|
CA338320895 rs1388734170 |
1296 | E>D | No |
ClinGen gnomAD |
|
|
CA338320868 rs765741134 |
1296 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs765741134 CA580556 |
1296 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs775921159 CA580557 |
1299 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA338321002 rs140883136 |
1300 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1403368995 CA338321020 |
1301 | D>N | No |
ClinGen TOPMed |
No associated diseases with O95155
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| ubiquitin ligase complex | A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| enzyme binding | Binding to an enzyme, a protein with catalytic activity. |
| ubiquitin-ubiquitin ligase activity | Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| granzyme-mediated apoptotic signaling pathway | The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. |
| proteasome-mediated ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
| protein polyubiquitination | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. |
| response to UV | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. |
| ubiquitin-dependent ERAD pathway | The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. |
| ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEELSADEIR | RRRLARLAGG | QTSQPTTPLT | SPQRENPPGP | PIAASAPGPS | QSLGLNVHNM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TPATSPIGAS | GVAHRSQSSE | GVSSLSSSPS | NSLETQSQSL | SRSQSMDIDG | VSCEKSMSQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVDSGIENME | VDENDRREKR | SLSDKEPSSG | PEVSEEQALQ | LVCKIFRVSW | KDRDRDVIFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SSLSAQFKQN | PKEVFSDFKD | LIGQILMEVL | MMSTQTRDEN | PFASLTATSQ | PIAAAARSPD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RNLLLNTGSN | PGTSPMFCSV | ASFGASSLSS | LYESSPAPTP | SFWSSVPVMG | PSLASPSRAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SQLAVPSTPL | SPHSAASGTA | AGSQPSSPRY | RPYTVTHPWA | SSGVSILSSS | PSPPALASSP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QAVPASSSRQ | RPSSTGPPLP | PASPSATSRR | PSSLRISPSL | GASGGASNWD | SYSDHFTIET |
| 430 | 440 | 450 | 460 | 470 | 480 |
| CKETDMLNYL | IECFDRVGIE | EKKAPKMCSQ | PAVSQLLSNI | RSQCISHTAL | VLQGSLTQPR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SLQQPSFLVP | YMLCRNLPYG | FIQELVRTTH | QDEEVFKQIF | IPILQGLALA | AKECSLDSDY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FKYPLMALGE | LCETKFGKTH | PVCNLVASLR | LWLPKSLSPG | CGRELQRLSY | LGAFFSFSVF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AEDDVKVVEK | YFSGPAITLE | NTRVVSQSLQ | HYLELGRQEL | FKILHSILLN | GETREAALSY |
| 670 | 680 | 690 | 700 | 710 | 720 |
| MAAVVNANMK | KAQMQTDDRL | VSTDGFMLNF | LWVLQQLSTK | IKLETVDPTY | IFHPRCRITL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PNDETRVNAT | MEDVNDWLTE | LYGDQPPFSE | PKFPTECFFL | TLHAHHLSIL | PSCRRYIRRL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| RAIRELNRTV | EDLKNNESQW | KDSPLATRHR | EMLKRCKTQL | KKLVRCKACA | DAGLLDESFL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RRCLNFYGLL | IQLLLRILDP | AYPDITLPLN | SDVPKVFAAL | PEFYVEDVAE | FLFFIVQYSP |
| 910 | 920 | 930 | 940 | 950 | 960 |
| QALYEPCTQD | IVMFLVVMLC | NQNYIRNPYL | VAKLVEVMFM | TNPAVQPRTQ | KFFEMIENHP |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| LSTKLLVPSL | MKFYTDVEHT | GATSEFYDKF | TIRYHISTIF | KSLWQNIAHH | GTFMEEFNSG |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| KQFVRYINML | INDTTFLLDE | SLESLKRIHE | VQEEMKNKEQ | WDQLPRDQQQ | ARQSQLAQDE |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| RVSRSYLALA | TETVDMFHIL | TKQVQKPFLR | PELGPRLAAM | LNFNLQQLCG | PKCRDLKVEN |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| PEKYGFEPKK | LLDQLTDIYL | QLDCARFAKA | IADDQRSYSK | ELFEEVISKM | RKAGIKSTIA |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| IEKFKLLAEK | VEEIVAKNAR | AEIDYSDAPD | EFRDPLMDTL | MTDPVRLPSG | TIMDRSIILR |
| 1270 | 1280 | 1290 | 1300 | ||
| HLLNSPTDPF | NRQTLTESML | EPVPELKEQI | QAWMREKQNS | DH |