O81488
Gene name |
AL4 (At5g26210, F9D12.13, T19G15_60) |
Protein name |
PHD finger protein ALFIN-LIKE 4 |
Names |
Protein AL4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G26210 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O81488
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1WE9 | NMR | - | A | 201-251 | PDB |
| AF-O81488-F1 | Predicted | AlphaFoldDB |
7 variants for O81488
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00650173 | 3 | A>V | No | 1000Genomes | |
| ENSVATH11075290 | 86 | A>V | No | 1000Genomes | |
| ENSVATH11075241 | 169 | S>F | No | 1000Genomes | |
| ENSVATH07049998 | 170 | R>H | No | 1000Genomes | |
| ENSVATH03129378 | 181 | D>E | No | 1000Genomes | |
| ENSVATH14208710 | 206 | G>C | No | 1000Genomes | |
| tmp_5_9158665_C_A | 223 | M>I | No | 1000Genomes |
No associated diseases with O81488
3 regional properties for O81488
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| methylated histone binding | Binding to a histone in which a residue has been modified by methylation. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
| transcription coregulator activity | A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q84TV4 | Os03g0818300 | PHD finger protein ALFIN-LIKE 3 | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEAGGAYNPR | TVEEVFRDFK | GRRAGMIKAL | TTDVQEFFRL | CDPEKENLCL | YGHPNEHWEV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NLPAEEVPPE | LPEPVLGINF | ARDGMAEKDW | LSLVAVHSDA | WLLAVAFFFG | ARFGFDKADR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KRLFNMVNDL | PTIFEVVAGT | AKKQGKDKSS | VSNNSSNRSK | SSSKRGSESR | AKFSKPEPKD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DEEEEEEGVE | EEDEDEQGET | QCGACGESYA | ADEFWICCDL | CEMWFHGKCV | KITPARAEHI |
| 250 | |||||
| KQYKCPSCSN | KRARS |