AiPD: Autoinhibited Protein Database

O75691

Gene name	UTP20 (DRIM)
Protein name	Small subunit processome component 20 homolog
Names	Down-regulated in metastasis protein, Novel nucleolar protein 73, NNP73, Protein Key-1A6
Species	Homo sapiens (Human)
KEGG Pathway	hsa:27340
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1690-1776 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1690-1776 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

3 structures for O75691

Entry ID	Method	Resolution	Chain	Position	Source
7MQ8	EM	360 A	SP	1-2785	PDB
7MQ9	EM	387 A	SP	1-2785	PDB
7MQA	EM	270 A	SP	1-2785	PDB

2125 variants for O75691

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA386251321 rs1486690302	3	T>I		No	ClinGen gnomAD
rs1047957812 CA242155722	3	T>P		No	ClinGen TOPMed gnomAD
CA386251330 rs1186890675	4	K>N		No	ClinGen TOPMed gnomAD
CA242155724 rs903392204	5	P>S		No	ClinGen Ensembl
rs1431115269 CA386251341	6	V>A		No	ClinGen gnomAD
CA386251337 rs1461879567	6	V>I		No	ClinGen TOPMed
rs1593413354 CA386251366	10	T>A		No	ClinGen Ensembl
CA386251370 rs1429335228	10	T>I		No	ClinGen gnomAD
rs1037758439 CA242155729	11	E>D		No	ClinGen TOPMed
rs1157518164 CA386251391	13	T>I		No	ClinGen gnomAD
rs1327668743 CA386251392	14	Y>D		No	ClinGen TOPMed gnomAD
rs1327668743 CA386251394	14	Y>H		No	ClinGen TOPMed gnomAD
CA386251400 rs1431885310	15	R>W		No	ClinGen gnomAD
CA6741554 rs777483339 COSM1358125	19	F>C	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA386251460 rs1311999347	22	R>*		No	ClinGen gnomAD
rs151017457 CA6741555	22	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs770835593 CA6741556 CA6741557	24	G>R		No	ClinGen ExAC TOPMed gnomAD
rs201119620 CA242155942	25	N>D		No	ClinGen TOPMed gnomAD
rs772093974 CA6741559	29	D>G		No	ClinGen ExAC gnomAD
rs1470261642 CA386251511	30	I>T		No	ClinGen gnomAD
CA386251531 rs1254828460	33	R>Q		No	ClinGen TOPMed
rs1181779838 CA386251530 COSM199541	33	R>W	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs1412281080 CA386251534	34	I>L		No	ClinGen gnomAD
rs1446753350 CA386251539	34	I>T		No	ClinGen gnomAD
TCGA novel	34	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386251551 rs1344179662	36	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs138442594 CA242155951	38	A>E		No	ClinGen ESP TOPMed gnomAD
rs1428039371 CA386251576	40	Y>H		No	ClinGen gnomAD
CA386251595 rs1355179634	42	E>G		No	ClinGen gnomAD
rs1275866065	43	E>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs766639911 CA6741582	45	E>A		No	ClinGen ExAC TOPMed gnomAD
CA386251794 rs766639911	45	E>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	46	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242157086 rs201613032	48	F>I		No	ClinGen 1000Genomes
CA6741584 rs199984180	49	F>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741583 rs199984180	49	F>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA386251866 rs1248010989	50	E>D		No	ClinGen gnomAD
CA386251875 rs1195783643	51	G>D		No	ClinGen gnomAD
CA6741585 rs767850144	51	G>S		No	ClinGen ExAC TOPMed gnomAD
rs574807809 CA6741587	53	L>Q		No	ClinGen 1000Genomes ExAC gnomAD
rs1171081345 CA386251957	57	E>*		No	ClinGen TOPMed gnomAD
CA386251953 rs1171081345	57	E>K		No	ClinGen TOPMed gnomAD
rs753446896 CA6741590	61	T>A		No	ClinGen ExAC
rs1419326275 CA6741591	61	T>I		No	ClinGen TOPMed
rs756918885 CA6741593	63	H>R		No	ClinGen ExAC gnomAD
CA6741594 rs778741912	64	F>Y		No	ClinGen ExAC gnomAD
CA386252045 rs1444527886	65	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA242157164 rs887997462	66	K>R		No	ClinGen Ensembl
TCGA novel	68	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs959303458 CA242157167	69	K>R		No	ClinGen TOPMed
TCGA novel	70	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6741624 rs772232391	72	I>T		No	ClinGen ExAC gnomAD
CA6741625 rs775873004	73	D>Y		No	ClinGen ExAC gnomAD
rs1232902128 CA386252191	74	K>R		No	ClinGen TOPMed
TCGA novel	74	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1171109336 CA386252249	77	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel CA6741627 rs542537526	78	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen 1000Genomes ExAC gnomAD
rs140064475 CA6741628	79	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs762468305 CA386252296 CA6741629	82	V>L		No	ClinGen ExAC TOPMed gnomAD
rs762468305 CA386252295	82	V>M		No	ClinGen ExAC TOPMed gnomAD
CA386252308 rs749945156	83	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs749945156 CA6741631	83	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA6741632 rs762707848	84	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA6741634 rs751332898	87	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1474140212 CA386252377	88	I>M		No	ClinGen TOPMed
rs375167600 CA6741636	88	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs149447402 CA6741635	88	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1360665519 CA386252416	93	K>E		No	ClinGen gnomAD
rs189494608 CA6741637	93	K>R		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	94	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs756081314 CA386252447	95	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs779027623 CA386252450	96	L>M		No	ClinGen ExAC TOPMed gnomAD
rs779027623 CA6741640	96	L>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs772296088 CA6741641	97	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1251101276 CA386252461	97	Q>K		No	ClinGen gnomAD
rs1244743209 CA386252479	98	V>A		No	ClinGen gnomAD
rs764439575 CA242157203	98	V>I		No	ClinGen gnomAD
CA386252500 rs1445080915	100	N>K		No	ClinGen gnomAD
rs1167511207 CA386252501	101	S>R		No	ClinGen TOPMed gnomAD
CA6741643 rs747342486	104	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	104	Y>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs143875613 CA6741644	107	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368079018 CA6741646	109	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs78440807 CA6741645	109	D>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386252891 rs1287507270	110	L>F		No	ClinGen gnomAD
CA6741666 rs755292222	112	V>A		No	ClinGen ExAC gnomAD
CA386252899 rs1364582190	112	V>L		No	ClinGen gnomAD
CA386252933 rs1300922546	116	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
TCGA novel	117	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6741669 rs2290723	120	M>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6741667 rs781676133	120	M>L		No	ClinGen ExAC TOPMed gnomAD
CA6741668 VAR_055135 rs2290723	120	M>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs781676133 CA386252975	120	M>V		No	ClinGen ExAC TOPMed gnomAD
rs1324216456 CA386253032	124	P>L		No	ClinGen TOPMed gnomAD
rs773600658 CA6741670	124	P>S		No	ClinGen ExAC TOPMed gnomAD
CA386253038 rs1258709083	125	H>R		No	ClinGen gnomAD
rs1215046089 CA386253036	125	H>Y		No	ClinGen gnomAD
rs369418489 CA242157314	126	F>L		No	ClinGen ESP TOPMed gnomAD
rs749860562 CA6741671	127	P>T		No	ClinGen ExAC gnomAD
TCGA novel	129	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242157319 rs967727528	129	F>L		No	ClinGen Ensembl
rs761528888	131	L>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA6741675 rs773948737	131	L>F		No	ClinGen ExAC TOPMed gnomAD
rs761528888	131	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs373688404 CA6741676	132	T>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1193683579 CA386253139	134	T>A		No	ClinGen gnomAD
rs147399996 CA6741677 COSM286419	135	S>L	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA6741679 rs760465766	136	I>T		No	ClinGen ExAC
rs1371439798 CA386253208	140	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA6741681 rs753707234	141	D>N		No	ClinGen ExAC TOPMed gnomAD
CA386253272 rs1406794433	144	L>S		No	ClinGen TOPMed gnomAD
rs907528322 CA242157344	145	L>I		No	ClinGen TOPMed gnomAD
CA6741683 rs145256826	146	E>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741684 rs751739229	150	T>A		No	ClinGen ExAC gnomAD
CA6741686 rs781599831	151	S>A		No	ClinGen ExAC gnomAD
CA6741687 rs376796297	151	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs376796297 CA386253355 COSM1358128	151	S>W	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA6741688 rs756451766	152	L>S		No	ClinGen ExAC TOPMed gnomAD
rs749723360 CA6741690	153	S>*		No	ClinGen ExAC gnomAD
rs201815900 CA6741689	153	S>P		No	ClinGen 1000Genomes ExAC gnomAD
CA6741691 rs771513621	154	Y>C		No	ClinGen ExAC gnomAD
rs1342829764 CA386253381	154	Y>H		No	ClinGen TOPMed
rs773800381 CA6741692	155	L>R		No	ClinGen ExAC gnomAD
CA6741693 rs745413991	156	Y>C		No	ClinGen ExAC
CA386253436 rs1299725788	158	Y>H		No	ClinGen TOPMed
rs1231883081 CA386253490	160	W>C		No	ClinGen TOPMed
rs1163367785 CA386253550	163	M>K		No	ClinGen gnomAD
RCV000962474 CA6741697 rs142220773	167	M>I		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs147632286 CA6741695	167	M>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs147632286 CA6741696	167	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741698 rs776529179	168	S>C		No	ClinGen ExAC gnomAD
rs200657881 CA6741699	169	S>I		No	ClinGen 1000Genomes ExAC gnomAD
CA6741700 rs765245286	170	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs752936556 CA6741715	173	M>I		No	ClinGen ExAC gnomAD
rs998194291 CA242157936	173	M>T		No	ClinGen Ensembl
CA386254014 rs1408238650	175	S>G		No	ClinGen gnomAD
CA242157940 rs566754342	176	T>I		No	ClinGen gnomAD
CA242157943 rs865912868	177	L>F		No	ClinGen gnomAD
rs1336075160 CA386254083	179	A>T		No	ClinGen gnomAD
TCGA novel	180	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6741717 rs761702669	180	H>Y		No	ClinGen ExAC gnomAD
CA6741718 rs146982196	181	K>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1315268123 CA386254147	182	K>E		No	ClinGen gnomAD
CA6741719 rs567907949	183	L>P		No	ClinGen 1000Genomes ExAC
CA6741721 rs535107469	184	H>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386254184 rs1274459581	184	H>Y		No	ClinGen gnomAD
CA6741722 rs555371440	185	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386254243 rs1383919700	187	N>S		No	ClinGen TOPMed
rs764407781 CA6741724	189	A>T		No	ClinGen ExAC TOPMed gnomAD
CA6741726 rs368669699	193	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1444997495 CA386254358	195	F>L		No	ClinGen gnomAD
CA6741727 rs187729337	196	L>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs758944883 CA6741729	197	M>V		No	ClinGen ExAC gnomAD
CA386254422 rs1175539996	199	K>Q		No	ClinGen gnomAD
rs376412636 CA6741747	201	S>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386254588 rs1205625954	202	D>G		No	ClinGen TOPMed
CA386254586 rs1243893306	202	D>Y		No	ClinGen TOPMed
TCGA novel	204	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1348553737 COSM1706098 CA386254604	204	N>S	skin [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1319804145 CA386254610	205	A>E		No	ClinGen gnomAD
CA386254608 rs750971526	205	A>S		No	ClinGen ExAC TOPMed gnomAD
CA6741749 rs750971526	205	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6741751 rs780629141	207	F>S		No	ClinGen ExAC gnomAD
CA242158297 rs974542710	208	N>S		No	ClinGen Ensembl
rs755877160 CA386254642	210	M>K		No	ClinGen ExAC TOPMed gnomAD
rs755877160 CA6741753	210	M>T		No	ClinGen ExAC TOPMed gnomAD
rs796192637 CA242158302	210	M>V		No	ClinGen TOPMed gnomAD
rs1460435166 CA386254654	211	F>L		No	ClinGen Ensembl
CA6741754 rs777657859	212	L>I		No	ClinGen ExAC gnomAD
CA386254683 rs1348911016	216	K>E		No	ClinGen gnomAD
rs1225866719 CA386254695	217	H>L		No	ClinGen gnomAD
rs749123222 CA6741755	218	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1336885951 CA386254699	218	P>S		No	ClinGen TOPMed
CA386254713 rs1490242538	220	K>E		No	ClinGen gnomAD
rs1382058797 CA386254723	221	V>A		No	ClinGen TOPMed
CA386254726 rs1220589083	222	E>Q		No	ClinGen gnomAD
rs1219252817 CA386254739	224	V>I		No	ClinGen Ensembl
TCGA novel	224	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6741756 rs770923470	226	Q>R		No	ClinGen ExAC
rs1161436654 CA386254765	228	L>F		No	ClinGen TOPMed
rs1042382250 CA242158314	228	L>P		No	ClinGen TOPMed
TCGA novel	230	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386255104 rs1386105412	231	M>I		No	ClinGen TOPMed
CA6741757 rs774357952	232	C>R		No	ClinGen ExAC gnomAD
CA6741758 rs528105491	233	K>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs866407245 CA242158320	237	N>T		No	ClinGen Ensembl
rs201614926 CA6741759	238	M>T		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	238	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776616066 CA6741760	241	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs762000750 CA6741761	242	C>G		No	ClinGen ExAC gnomAD
CA6741762 rs765467951	243	T>I		No	ClinGen ExAC gnomAD
CA386255275 rs1423572444	244	G>D		No	ClinGen TOPMed gnomAD
rs1423572444 CA386255279	244	G>V		No	ClinGen TOPMed gnomAD
rs763314193 CA6741764	245	Q>*		No	ClinGen ExAC gnomAD
rs753739452 CA242158421	246	A>S		No	ClinGen TOPMed gnomAD
rs753739452 CA386255355	246	A>T		No	ClinGen TOPMed gnomAD
CA6741778 rs771952656	252	R>*		No	ClinGen ExAC TOPMed gnomAD
CA6741777 rs771952656	252	R>G		No	ClinGen ExAC TOPMed gnomAD
CA6741779 rs372093743	252	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs769938158 CA6741781	253	K>N		No	ClinGen ExAC TOPMed gnomAD
CA242158436 rs965537886	258	T>A		No	ClinGen TOPMed
CA6741782 rs551412332	259	E>A		No	ClinGen 1000Genomes ExAC gnomAD
CA386255525 rs1249653730	259	E>D		No	ClinGen gnomAD
CA6741783 rs771327304	260	T>A		No	ClinGen ExAC gnomAD
rs774622092 CA6741784	260	T>K		No	ClinGen ExAC gnomAD
TCGA novel	261	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1258645092 CA386255617	263	Q>H		No	ClinGen TOPMed gnomAD
CA242158444 rs890775309	265	P>Q		No	ClinGen gnomAD
CA6741786 rs767936184	266	W>R		No	ClinGen ExAC TOPMed gnomAD
rs1192111573 CA386255671	267	M>I		No	ClinGen gnomAD
rs1423999324 CA386255667	267	M>T		No	ClinGen gnomAD
rs994342175 CA242158450	268	L>V		No	ClinGen TOPMed
rs760272496 CA6741788	270	G>E		No	ClinGen ExAC gnomAD
rs752186235 CA6741787	270	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs375265829 CA6741789	272	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741792 rs367568587	275	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA386255801 rs1441223197	276	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA6741795 rs758317481	280	T>A		No	ClinGen ExAC TOPMed gnomAD
rs1293777974 CA386255868	281	V>L		No	ClinGen gnomAD
rs139257599 CA6741796	282	S>F		No	ClinGen 1000Genomes ExAC gnomAD
rs777900025 CA6741799	283	Y>F		No	ClinGen ExAC gnomAD
CA386255901 rs749485098	284	I>L		No	ClinGen ExAC gnomAD
CA6741800 rs749485098	284	I>V		No	ClinGen ExAC gnomAD
rs1238653778 CA386255939	287	E>K		No	ClinGen TOPMed
rs774733708 CA6741802	288	H>R		No	ClinGen ExAC gnomAD
rs771077454 CA6741801	288	H>Y		No	ClinGen ExAC gnomAD
rs1204130358 CA386255971	289	F>L		No	ClinGen TOPMed gnomAD
rs1204130358 CA386255969	289	F>V		No	ClinGen TOPMed gnomAD
CA386255989 rs1259244073	290	G>D		No	ClinGen gnomAD
CA386255992 rs1259244073	290	G>V		No	ClinGen gnomAD
rs759820954 CA6741803	291	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1286560927 CA386256009	292	F>V		No	ClinGen TOPMed
CA6741804 rs772569765	294	E>*		No	ClinGen ExAC gnomAD
rs993004530 CA242158487	295	C>R		No	ClinGen TOPMed
CA386256095 rs776125449 CA6741805	297	Q>H		No	ClinGen ExAC gnomAD
CA6741825 rs769309900	298	E>G		No	ClinGen ExAC gnomAD
rs1271571058 CA606692801	299	S>*		No	ClinGen gnomAD
CA6741826 rs146584077	299	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386256179 rs146584077	299	S>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386256204 rs1411080564	301	L>W		No	ClinGen TOPMed
CA6741829 rs772729936 COSM3792091	302	D>N	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA242158743 rs1010866471	302	D>V		No	ClinGen TOPMed gnomAD
rs369745646 CA242158745	304	H>Y		No	ClinGen ESP TOPMed gnomAD
rs1436601083 CA386256250	305	T>A		No	ClinGen gnomAD
CA386256253 rs765166437	305	T>I		No	ClinGen TOPMed gnomAD
CA242158748 rs765166437	305	T>R		No	ClinGen TOPMed gnomAD
CA386256287 rs1240400613	308	T>A		No	ClinGen gnomAD
CA242158752 rs975985411	310	T>S		No	ClinGen TOPMed
rs1182038631 CA386256357	311	N>K		No	ClinGen gnomAD
rs765360190 CA242158757	314	E>D		No	ClinGen Ensembl
CA6741832 rs751410004	314	E>K		No	ClinGen ExAC gnomAD
rs754866885 CA6741833	318	Q>E		No	ClinGen ExAC gnomAD
CA386256500 rs1223167575	319	I>F		No	ClinGen gnomAD
CA6741834 rs767443404	319	I>M		No	ClinGen ExAC
rs148365055 CA6741836	320	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs148365055 CA6741835	320	K>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA386256601 rs951390222	324	E>D		No	ClinGen TOPMed gnomAD
rs746045285 CA6741838	325	T>P		No	ClinGen ExAC TOPMed gnomAD
rs780516465 CA386256677	328	I>R		No	ClinGen ExAC TOPMed gnomAD
CA6741840 rs780516465	328	I>T		No	ClinGen ExAC TOPMed gnomAD
CA386256684 rs1186236763	329	L>F		No	ClinGen TOPMed gnomAD
rs769219972 CA6741842	332	H>D		No	ClinGen ExAC gnomAD
rs982879239 CA242158778	332	H>R		No	ClinGen TOPMed gnomAD
rs777291998 CA6741843	333	G>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	334	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs141602307 CA242158783	334	S>R		No	ClinGen ESP TOPMed
CA386256789 rs1347771535	334	S>R		No	ClinGen TOPMed
rs769184944 CA386256842	338	I>R		No	ClinGen ExAC gnomAD
CA6741845 rs769184944	338	I>T		No	ClinGen ExAC gnomAD
rs75620118 CA6741847	339	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs75620118 CA6741846 RCV000963707	339	P>T		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs373233138 CA6741848	340	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA386256875 rs1229722695	341	P>S		No	ClinGen gnomAD
CA6741850 rs759335513	342	A>T		No	ClinGen ExAC gnomAD
rs201873038 CA6741852	343	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6741854 rs765207753	344	V>A		No	ClinGen ExAC gnomAD
CA6741853 rs138400123	344	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741855 rs750538032	345	C>Y		No	ClinGen ExAC TOPMed gnomAD
CA386257005 rs1433151106	348	L>V		No	ClinGen Ensembl
rs764123747 CA6741874	349	S>A		No	ClinGen ExAC gnomAD
CA386257022 rs952491692	349	S>C		No	ClinGen gnomAD
CA242158841 rs952491692	349	S>F		No	ClinGen gnomAD
CA6741875 rs750404350	351	T>A		No	ClinGen ExAC gnomAD
rs544207946 CA6741876	351	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6741878 rs751829217	352	L>P		No	ClinGen ExAC gnomAD
rs755294188 CA6741880	353	Q>H		No	ClinGen ExAC
rs1436726138 CA386257060	353	Q>K		No	ClinGen TOPMed
CA386257068 rs1344265931	353	Q>R		No	ClinGen gnomAD
rs753131749 CA6741881	354	V>L		No	ClinGen ExAC gnomAD
rs756543556 CA6741882	355	A>V		No	ClinGen ExAC gnomAD
CA242158858 rs142738390	357	L>P		No	ClinGen ESP TOPMed
CA242158861 rs142738390	357	L>R		No	ClinGen ESP TOPMed
rs1340664116 CA386257131	358	S>F		No	ClinGen gnomAD
CA6741884 rs139573850	359	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA386257138 rs1281942323	359	T>S		No	ClinGen gnomAD
CA386257167 rs1283767968	361	C>F		No	ClinGen gnomAD
CA242158868 rs1007380576	362	W>R		No	ClinGen TOPMed
rs778432035 CA6741886	365	L>F		No	ClinGen ExAC gnomAD
CA242158874 rs981984342	365	L>P		No	ClinGen Ensembl
rs1593419019 CA386257249	367	D>A		No	ClinGen Ensembl
rs771777235 CA6741888	367	D>E		No	ClinGen ExAC gnomAD
rs1263984046 CA386257246	367	D>N		No	ClinGen gnomAD
CA386257259 rs1198517590	368	V>L		No	ClinGen gnomAD
CA6741889 rs775106501	370	S>P		No	ClinGen ExAC gnomAD
CA386257277 rs1192033747	371	A>T		No	ClinGen TOPMed
rs1478861399 CA386257297	374	L>Q		No	ClinGen gnomAD
rs760523413 CA6741890	375	G>D		No	ClinGen ExAC gnomAD
RCV000879078 rs79571582 CA6741891	377	N>Y		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA386257328 rs1417482180	379	S>A		No	ClinGen gnomAD
CA6741892 rs750820584	381	P>L		No	ClinGen ExAC TOPMed gnomAD
CA386257349 rs1337455632	382	E>A		No	ClinGen gnomAD
rs1231649849 CA386257352	383	T>P		No	ClinGen TOPMed
rs751741275 CA6741895	385	I>V		No	ClinGen ExAC gnomAD
TCGA novel	386	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386257370 rs1205088713	386	K>Q		No	ClinGen gnomAD
CA6741896 rs759786580	386	K>R		No	ClinGen ExAC TOPMed gnomAD
CA386257382 rs1219517792	387	E>G		No	ClinGen TOPMed
rs1279304110 CA386257389	388	T>S		No	ClinGen gnomAD
rs756483939 CA6741899	389	I>T		No	ClinGen ExAC gnomAD
CA6741898 rs151242689	389	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs764430776 CA6741900	390	E>K		No	ClinGen ExAC gnomAD
rs1210294486 CA386257445	394	E>D		No	ClinGen gnomAD
CA386257457 rs1272203105	396	R>T		No	ClinGen TOPMed gnomAD
TCGA novel	400	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs201186982 CA6741920	400	R>H	Variant assessed as Somatic; 4.63e-05 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	400	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1238612281 CA386257494	401	L>S		No	ClinGen gnomAD
CA6741922 rs765765635	404	S>C		No	ClinGen ExAC gnomAD
rs1012291517 CA242159221	404	S>R		No	ClinGen Ensembl
CA386257533 rs1472844098	407	E>K		No	ClinGen gnomAD
TCGA novel	408	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1398770595 CA386257549	409	M>L		No	ClinGen TOPMed gnomAD
rs1031769402 CA242159228	411	A>S		No	ClinGen TOPMed
CA242159230 rs868254939	411	A>V		No	ClinGen gnomAD
CA6741925 rs779469626	412	M>T		No	ClinGen ExAC gnomAD
TCGA novel	417	Q>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746667615 CA6741926	417	Q>K		No	ClinGen ExAC gnomAD
rs754588793 CA6741948	421	P>A		No	ClinGen ExAC gnomAD
CA6741949 rs144211284	424	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA242159926 rs994431858	426	Y>C		No	ClinGen Ensembl
rs200302469 CA6741950	427	I>V		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	430	C>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386258716 rs1178657423	432	L>I		No	ClinGen TOPMed gnomAD
rs146565929 CA6741951	433	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1453314070 CA386258746	434	D>V		No	ClinGen gnomAD
rs1396311455 CA386258754	435	D>N		No	ClinGen TOPMed gnomAD
rs1362473601 CA386258775	437	V>I		No	ClinGen gnomAD
rs1298681487 CA386258801	440	D>V		No	ClinGen gnomAD
CA386258810 rs1452538775	441	E>D		No	ClinGen gnomAD
rs747091698 CA6741956	457	P>H		No	ClinGen ExAC TOPMed gnomAD
CA6741958 rs141301122	458	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA242159935 rs141301122	458	T>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741959 rs762062106	460	G>D		No	ClinGen ExAC TOPMed gnomAD
CA386259004 rs762062106	460	G>V		No	ClinGen ExAC TOPMed gnomAD
CA6741961 rs773504931	461	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs773504931 CA386259015	461	S>W		No	ClinGen ExAC TOPMed gnomAD
rs766797905 CA6741963	463	A>T		No	ClinGen ExAC TOPMed gnomAD
CA6741964 rs751036728	467	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	467	Y>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs758986812 CA6741965	468	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1382425150 CA386259127	470	V>I		No	ClinGen gnomAD
CA6741966 rs145108682	473	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741967 rs145108682	473	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741968 rs145108682	473	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741970 rs183927312	474	Q>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386259206 rs1295237257	476	V>L		No	ClinGen gnomAD
CA6741972 rs374596406	477	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA6741984 rs145833993	478	F>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201256747 CA6741985	479	Y>F		No	ClinGen 1000Genomes ExAC gnomAD
CA386259802 rs1565787549	480	I>R		No	ClinGen Ensembl
CA386259814 COSM1288875 rs1565787551	482	Q>*	Variant assessed as Somatic; 0.0 impact. autonomic_ganglia [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated Ensembl NCI-TCGA
CA6741987 rs775157725	482	Q>H		No	ClinGen ExAC gnomAD
rs149002619 CA6741986	482	Q>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA386259829 rs1376259112	484	K>T		No	ClinGen gnomAD
rs200955631 CA6741988	485	T>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386259854 rs1311588317	488	K>E		No	ClinGen TOPMed
CA386259858 rs1317813459	488	K>N		No	ClinGen gnomAD
rs1217408485 CA386259867	490	R>G		No	ClinGen gnomAD
TCGA novel	490	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs143832042 CA6741990	490	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6741992 rs765120524	492	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA242162018 rs1056411266	492	E>V		No	ClinGen gnomAD
CA386259888 rs1484251317	493	Q>*		No	ClinGen gnomAD
CA6741993 rs750322929	493	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs535772659 CA6741994	494	F>L		No	ClinGen 1000Genomes ExAC gnomAD
rs555637284 CA6741995	494	F>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1466704062 CA386259900	495	P>A		No	ClinGen TOPMed gnomAD
CA6741998 rs777877274	498	D>V		No	ClinGen ExAC gnomAD
rs1357050671 CA386259926	499	H>D		No	ClinGen gnomAD
CA6741999 rs749569519	499	H>R		No	ClinGen ExAC TOPMed gnomAD
CA6742003 rs4764643 VAR_022162	502	S>C		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs4764643 CA6742004	502	S>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742002 rs746321739	502	S>P		No	ClinGen ExAC gnomAD
rs760286700 CA6742005	503	I>L		No	ClinGen ExAC gnomAD
TCGA novel	503	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242162071 rs1000017917	505	K>N		No	ClinGen Ensembl
CA6742007 rs776116771	507	P>L		No	ClinGen ExAC gnomAD
CA6742006 rs763709062	507	P>T		No	ClinGen ExAC TOPMed gnomAD
CA6742008 rs761592473	508	P>L		No	ClinGen ExAC TOPMed gnomAD
CA6742009 rs764927303	509	N>H		No	ClinGen ExAC gnomAD
TCGA novel	511	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242162083 rs530927598	519	W>L		No	ClinGen Ensembl
CA6742010 rs758248732	520	A>T		No	ClinGen ExAC gnomAD
CA6742013 rs139131985	523	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386260120 rs1444885762	524	V>A		No	ClinGen Ensembl
CA6742015 rs144043776	524	V>M		No	ClinGen 1000Genomes ExAC gnomAD
rs954562180 CA242162121	526	P>H		No	ClinGen TOPMed gnomAD
rs954562180 CA386260149	526	P>L		No	ClinGen TOPMed gnomAD
rs983657120 CA242162128	527	H>P		No	ClinGen TOPMed
rs983657120 CA386260160	527	H>R		No	ClinGen TOPMed
rs997502771 CA242162131	528	I>V		No	ClinGen Ensembl
rs919911727 CA242162221	531	L>F		No	ClinGen TOPMed
CA6742033 rs764027603	535	K>R		No	ClinGen ExAC TOPMed gnomAD
rs1405274243 CA386260305	536	V>L		No	ClinGen gnomAD
CA6742035 rs757384332	538	P>L		No	ClinGen ExAC TOPMed gnomAD
rs753959114 CA6742034	538	P>T		No	ClinGen ExAC gnomAD
rs1434492415 CA386260350	539	L>P		No	ClinGen TOPMed gnomAD
CA6742038 rs373930284	540	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742039 rs780632896	541	T>A		No	ClinGen ExAC gnomAD
rs137961955 CA6742041	542	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1453063359 CA386260396	543	F>C		No	ClinGen gnomAD
TCGA novel	543	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386260447 rs1214065627	547	L>R		No	ClinGen gnomAD
CA6742043 rs747723866	548	F>L		No	ClinGen ExAC gnomAD
CA6742045 CA242162257 rs769278795	549	M>L		No	ClinGen ExAC TOPMed gnomAD
CA6742046 rs762629718	549	M>R		No	ClinGen ExAC gnomAD
CA6742044 rs769278795	549	M>V		No	ClinGen ExAC TOPMed gnomAD
CA386260464 rs1363815189	550	T>N		No	ClinGen gnomAD
rs1472182506 CA386260467	551	V>I		No	ClinGen TOPMed gnomAD
CA6742047 rs150558479	552	D>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742048 rs774149143	553	K>R		No	ClinGen ExAC TOPMed gnomAD
rs376003744 CA6742049	554	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	555	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386260493 rs1360515213	555	S>G		No	ClinGen TOPMed
CA6742050 rs767524170	556	F>L		No	ClinGen ExAC gnomAD
TCGA novel	557	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753815915 CA6742051	558	K>N		No	ClinGen ExAC TOPMed gnomAD
CA386260707 rs1277497687	561	L>S		No	ClinGen gnomAD
rs774094260 CA6742066	561	L>V		No	ClinGen ExAC TOPMed gnomAD
rs771813278 CA6742068	562	F>L		No	ClinGen ExAC gnomAD
rs1343814165 CA386260738	563	V>A		No	ClinGen gnomAD
CA386260729 rs1251724305	563	V>I		No	ClinGen gnomAD
CA386260760 rs1198430173	565	C>Y		No	ClinGen gnomAD
CA242163413 rs1040408893	566	Q>E		No	ClinGen TOPMed gnomAD
rs775468260 CA6742069	567	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1485715018 CA386260797	568	V>I		No	ClinGen gnomAD
TCGA novel	569	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742071 rs765394903	570	T>I		No	ClinGen ExAC gnomAD
TCGA novel	570	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742072 rs773438739	571	L>V		No	ClinGen ExAC gnomAD
rs751820486 CA6742077	576	E>D		No	ClinGen ExAC gnomAD
CA386260935 rs1164472939	578	S>Y		No	ClinGen TOPMed
rs370416680 CA6742078	582	H>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742080 rs138606783	588	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs138606783 CA6742081	588	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742082 rs748832576	588	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6742083 rs748832576	588	R>L		No	ClinGen ExAC TOPMed gnomAD
rs149303591 CA6742084	590	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742085 rs745548972	593	V>I		No	ClinGen ExAC gnomAD
CA6742108 rs768665973	595	T>P		No	ClinGen ExAC gnomAD
rs762533790 CA242165178	597	P>R		No	ClinGen Ensembl
rs1457481677 CA386261621	598	L>P		No	ClinGen gnomAD
rs1254065821 CA386261618	598	L>V		No	ClinGen TOPMed gnomAD
TCGA novel	600	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1410168260 CA386261642	600	P>S		No	ClinGen gnomAD
CA242165194 rs375432168	602	V>A		No	ClinGen ESP
rs1464041545 CA386261661	602	V>M		No	ClinGen TOPMed
rs774350834 CA6742112	604	L>Q		No	ClinGen ExAC gnomAD
CA6742114 rs772218043	608	L>I		No	ClinGen ExAC TOPMed gnomAD
CA386261743 rs1395015331	609	Y>C		No	ClinGen TOPMed gnomAD
rs1185621171 CA386261763	610	Y>C		No	ClinGen Ensembl
rs775877103 CA6742115	611	Q>L		No	ClinGen ExAC TOPMed gnomAD
rs1272110651 CA386261795	612	R>S		No	ClinGen TOPMed
CA6742116 rs761009435	618	C>Y		No	ClinGen ExAC gnomAD
rs1196289076 CA386261877	619	K>Q		No	ClinGen TOPMed
CA386261898 rs1341445648	620	G>A		No	ClinGen TOPMed
rs764486594 CA386261904	621	P>A		No	ClinGen ExAC gnomAD
rs764486594 CA6742117	621	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1235750427 CA386261956	625	E>G		No	ClinGen gnomAD
rs754339350 CA6742118	626	A>S		No	ClinGen ExAC gnomAD
CA386261998 TCGA novel rs1222403264	628	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen TOPMed
CA386261994 rs1317688470	628	M>T		No	ClinGen gnomAD
CA6742119 rs762365167	629	E>Q		No	ClinGen ExAC gnomAD
rs1323734878 CA386262028	630	L>I		No	ClinGen TOPMed
rs764748303 CA6742120	631	F>I		No	ClinGen ExAC gnomAD
CA6742121 rs749908188	633	K>R		No	ClinGen ExAC gnomAD
CA386262156 rs1254245581	636	A>V		No	ClinGen gnomAD
rs1167023929 CA386262240	640	T>I		No	ClinGen gnomAD
rs77834422 CA6742123	641	G>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1335547641 CA386262249	641	G>C		No	ClinGen TOPMed
rs751305487 CA6742124	642	V>I		No	ClinGen ExAC TOPMed
CA242165262 rs144582951	643	S>F		No	ClinGen ESP TOPMed gnomAD
rs1421477470 CA386262914	645	I>F		No	ClinGen gnomAD
rs765693560 CA6742138	645	I>S		No	ClinGen ExAC gnomAD
rs762347272 CA6742140	646	R>L		No	ClinGen ExAC TOPMed gnomAD
rs762347272 CA6742141	646	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs749897356 CA242166093	646	R>W		No	ClinGen ExAC gnomAD
TCGA novel	650	I>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742144 rs369024114	650	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA386262947 rs1565789287	651	R>K		No	ClinGen Ensembl
rs1398765387 CA386262951	651	R>S		No	ClinGen TOPMed gnomAD
rs144178978 CA6742145	653	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742147 rs777552384	659	Q>H		No	ClinGen ExAC gnomAD
rs756033604 CA6742146	659	Q>R		No	ClinGen ExAC gnomAD
CA6742148 rs749292591	664	M>V		No	ClinGen ExAC gnomAD
rs758407390 CA6742149	665	E>K		No	ClinGen ExAC gnomAD
CA6742169 rs757231752	666	D>G		No	ClinGen ExAC gnomAD
CA386263063 rs757231752	666	D>V		No	ClinGen ExAC gnomAD
CA386263102 rs1405337257	672	R>Q		No	ClinGen gnomAD
COSM242210 rs77466434 CA6742171	672	R>W	prostate [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1324301459 CA386263110	673	Q>L		No	ClinGen gnomAD
rs865882533 CA242167421	674	S>F		No	ClinGen Ensembl
CA242167422 rs78531646	677	A>S		No	ClinGen Ensembl
CA6742173 rs781367733	678	I>L		No	ClinGen ExAC TOPMed gnomAD
CA6742174 rs781367733	678	I>V		No	ClinGen ExAC TOPMed gnomAD
rs142367906 CA6742175	679	L>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742176 rs373556740	680	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs749696639 CA6742177	680	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6742178 rs749696639	680	R>L		No	ClinGen ExAC gnomAD
rs1000291507 CA242167471	682	A>E		No	ClinGen TOPMed
TCGA novel	684	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs151294243 CA242167479	685	V>F		No	ClinGen ESP TOPMed
rs1280250819 CA386263251	686	P>S		No	ClinGen gnomAD
rs773955980 CA6742179	688	T>S		No	ClinGen ExAC TOPMed gnomAD
rs1396009018 CA386263290	689	V>A		No	ClinGen TOPMed
rs1227729036 CA386263283	689	V>M		No	ClinGen gnomAD
CA386263302 rs1270973004	690	N>S		No	ClinGen gnomAD
CA386263314 rs1336674781	691	D>Y		No	ClinGen gnomAD
CA6742181 rs767178349	692	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1237206733 CA386263330	692	Y>D		No	ClinGen gnomAD
rs775006012 CA6742182	693	R>*		No	ClinGen ExAC gnomAD
rs77005911 CA6742183	693	R>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	696	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761700394 CA6742186	698	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA6742185 rs753671569	698	H>R		No	ClinGen ExAC gnomAD
CA386263490 rs1394561622	704	H>R		No	ClinGen gnomAD
rs1411928715 CA386263505	705	D>V		No	ClinGen TOPMed gnomAD
COSM933919 CA6742187 rs765182802	707	V>I	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA386263546 COSM3792092 rs1414015424	708	Q>H	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA386263552 rs1291395369	709	T>A		No	ClinGen gnomAD
CA242167553 rs1009150951	710	A>S		No	ClinGen TOPMed
rs1357072688 CA386263575	711	V>I		No	ClinGen gnomAD
CA6742188 rs750408958	712	P>L		No	ClinGen ExAC gnomAD
CA6742189 rs755017500	713	D>A		No	ClinGen ExAC gnomAD
rs962327787 CA242167567	713	D>E		No	ClinGen TOPMed
CA6742191 rs781316396	715	P>L		No	ClinGen ExAC TOPMed gnomAD
rs781316396 CA6742190	715	P>R		No	ClinGen ExAC TOPMed gnomAD
rs370762874 CA6742193	718	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs563341513 CA242168834	719	V>A		No	ClinGen Ensembl
CA6742211 rs756247390	719	V>L		No	ClinGen ExAC gnomAD
CA6742212 rs150039308	720	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386264086 rs1310961013	721	L>H		No	ClinGen TOPMed
COSM1358132 CA386264099 rs1194106783	722	R>C	Variant assessed as Somatic; 0.0 impact. large_intestine skin [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
COSM933920 rs1377258496 CA386264102	722	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1175003391 CA386264124	723	Y>C		No	ClinGen TOPMed
CA386264160 rs1452856127	725	L>*		No	ClinGen gnomAD
CA6742214 rs199642959	726	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742216 rs746323616	727	M>V		No	ClinGen ExAC gnomAD
CA6742217 rs772710430	728	L>P		No	ClinGen ExAC gnomAD
rs371232504 CA6742219	729	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs768101644 CA6742220	730	I>V		No	ClinGen ExAC TOPMed gnomAD
CA6742221 rs376351923	733	S>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA242168872 COSM2063225 rs376351923	733	S>N	central_nervous_system [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs1593426921 CA386264312	734	A>T		No	ClinGen Ensembl
rs761518561 CA6742222	736	W>*		No	ClinGen ExAC gnomAD
TCGA novel	738	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742223 rs368178402	740	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1593426937 CA386264446	741	E>A		No	ClinGen Ensembl
CA386264438 rs372446066	741	E>K		No	ClinGen ESP ExAC gnomAD
CA6742224 rs372446066	741	E>Q		No	ClinGen ESP ExAC gnomAD
rs1280354014 CA386264484	743	I>K		No	ClinGen TOPMed
rs1247490575 CA386264490	743	I>M		No	ClinGen gnomAD
rs1350119529 CA386264480	743	I>V		No	ClinGen TOPMed
CA386264494 rs1238907073	744	S>G		No	ClinGen gnomAD
CA386264497 rs1238907073	744	S>R		No	ClinGen gnomAD
rs772947510 CA6742245	746	H>R		No	ClinGen ExAC
rs769437203 CA6742244	746	H>Y		No	ClinGen ExAC gnomAD
rs569253169 CA242170903	748	H>L		No	ClinGen TOPMed
CA6742246 rs749099686	748	H>N		No	ClinGen ExAC gnomAD
CA6742248 rs548791318	749	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA242170942 rs921424681	750	M>K		No	ClinGen TOPMed
rs947336100 CA242170935	750	M>V		No	ClinGen TOPMed gnomAD
CA6742249 rs759453176	752	N>K		No	ClinGen ExAC gnomAD
rs1392415359 CA386264813	755	F>I		No	ClinGen gnomAD
CA6742251 rs142042282	760	Y>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs771476091 CA242170983	762	H>R		No	ClinGen TOPMed gnomAD
CA242170981 rs1041240779	762	H>Y		No	ClinGen Ensembl
CA386264875 rs1287605356	763	L>P		No	ClinGen TOPMed
rs765579418 CA6742253	763	L>V		No	ClinGen ExAC gnomAD
CA386264881 rs1226808409	764	E>G		No	ClinGen gnomAD
rs752091527 CA6742257	768	T>A		No	ClinGen ExAC gnomAD
CA6742258 COSM199551 rs755453169	768	T>M	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA386264912 rs1474206433	769	H>P		No	ClinGen gnomAD
rs1206095532 CA386264953	773	E>*		No	ClinGen TOPMed
rs753248883 CA6742278	773	E>V		No	ClinGen ExAC gnomAD
COSM933922 rs934531426 CA242171322	775	Q>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs755587225 CA6742279	776	N>I		No	ClinGen ExAC gnomAD
rs755587225 CA386264974	776	N>S		No	ClinGen ExAC gnomAD
CA386264973 rs755587225	776	N>T		No	ClinGen ExAC gnomAD
rs1440346893 CA386264977	777	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	778	M>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	778	M>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1291035437 CA386265007	780	D>E		No	ClinGen gnomAD
rs777325421 CA6742281	781	E>D		No	ClinGen ExAC gnomAD
rs1362911591 CA386265008	781	E>K		No	ClinGen gnomAD
CA242171350 COSM1706100 rs1040920690	783	S>F	skin [Cosmic]	No	ClinGen cosmic curated TOPMed
CA386265026 rs1040920690	783	S>Y		No	ClinGen TOPMed
TCGA novel	784	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753475253 CA6742282	784	V>I		No	ClinGen ExAC TOPMed gnomAD
rs753475253 CA6742283	784	V>L		No	ClinGen ExAC TOPMed gnomAD
rs778733436 CA6742284	786	D>G		No	ClinGen ExAC gnomAD
CA386265050 rs1389337278	787	E>G		No	ClinGen gnomAD
rs1279277357 CA386265053	788	S>R		No	ClinGen gnomAD
CA386265067 rs1213348726	789	W>*		No	ClinGen gnomAD
rs780109691 CA6742287	790	E>K		No	ClinGen ExAC gnomAD
CA386265082 rs1465059609	791	Q>L		No	ClinGen gnomAD
rs1022302681 CA242171401	793	Q>E		No	ClinGen TOPMed
CA6742288 rs747012443	793	Q>H		No	ClinGen ExAC gnomAD
CA386265105 rs1299984313	795	G>R		No	ClinGen TOPMed
CA242171405 rs142589004	796	D>G		No	ClinGen 1000Genomes gnomAD
rs1455209571 CA386265126	798	G>*		No	ClinGen gnomAD
TCGA novel	798	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742290 rs773438686	800	L>V		No	ClinGen ExAC TOPMed gnomAD
CA6742291 rs183129088	801	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386265183 rs1161712640	806	A>P		No	ClinGen TOPMed gnomAD
CA386265184 rs1161712640	806	A>S		No	ClinGen TOPMed gnomAD
CA386265181 rs1161712640	806	A>T		No	ClinGen TOPMed gnomAD
rs1389856320 CA386265329	814	R>G		No	ClinGen gnomAD
TCGA novel	814	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs143064975 CA6742292	814	R>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742293 rs774725398	816	D>E		No	ClinGen ExAC TOPMed gnomAD
rs759796303 CA6742294	820	F>C		No	ClinGen ExAC TOPMed gnomAD
CA386265512 rs1565790969	822	F>L		No	ClinGen Ensembl
rs767907847 CA6742295	822	F>L		No	ClinGen ExAC TOPMed gnomAD
rs767907847 CA6742296	822	F>V		No	ClinGen ExAC TOPMed gnomAD
rs148224454 CA6742297	827	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA386265612 rs1329641212 COSM933925	829	T>N	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA6742300 rs756889679	832	P>A		No	ClinGen ExAC gnomAD
CA386265655 rs1462895524	832	P>L		No	ClinGen TOPMed
TCGA novel	836	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs750134146 CA6742302	838	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs778411929 CA6742301	838	R>W		No	ClinGen ExAC gnomAD
CA6742303 rs758267087	840	R>G		No	ClinGen ExAC gnomAD
CA6742304 rs780049886	841	E>K		No	ClinGen ExAC TOPMed gnomAD
CA386265777 rs1356368141	843	S>F		No	ClinGen gnomAD
CA242171567 rs866980459	844	P>L		No	ClinGen Ensembl
rs746883525 CA6742305	844	P>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	844	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386265800 rs1406242380	847	L>S		No	ClinGen gnomAD
TCGA novel	850	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742309 rs141236784	851	N>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs141236784 CA6742308	851	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs528223192 CA6742326	852	N>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386266388 rs1308753600	852	N>S		No	ClinGen gnomAD
rs1270999205 CA386266393 COSM415675	853	E>Q	Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs748155809 CA6742327	854	Y>C		No	ClinGen ExAC gnomAD
rs148068961 CA6742328	856	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386266417 rs1291147923	856	P>S		No	ClinGen gnomAD
rs1301043812 CA386266420	857	A>T		No	ClinGen TOPMed
CA6742329 rs779105428	857	A>V		No	ClinGen ExAC gnomAD
CA6742330 rs746025682	864	T>I		No	ClinGen ExAC TOPMed gnomAD
rs746025682 CA6742331	864	T>N		No	ClinGen ExAC TOPMed gnomAD
rs775784330 CA6742332	865	Q>H		No	ClinGen ExAC gnomAD
rs776008041 CA242175991	866	D>N		No	ClinGen Ensembl
CA386266525 rs1274826256	866	D>V		No	ClinGen gnomAD
rs759190580 CA6742334	868	R>Q		No	ClinGen ExAC gnomAD
rs747352423 CA6742333	868	R>W		No	ClinGen ExAC TOPMed gnomAD
rs150773203 CA6742335	869	R>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742336 rs762442450	871	G>V		No	ClinGen ExAC gnomAD
rs1192976554 CA386266596	872	K>R		No	ClinGen gnomAD
CA386266612 rs1371519214	873	G>E		No	ClinGen gnomAD
rs1371519214 CA386266614	873	G>V		No	ClinGen gnomAD
rs1476549009 CA386266622	874	M>L		No	ClinGen gnomAD
rs764592255 CA6742337	874	M>T		No	ClinGen ExAC
CA242176021 rs867431510	875	V>A		No	ClinGen TOPMed gnomAD
TCGA novel	876	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386266671 rs1428976672	878	E>Q		No	ClinGen gnomAD
rs1593430345 CA386266686	879	I>T		No	ClinGen Ensembl
CA6742339 rs142705721	880	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs751305479 CA6742341	882	E>D		No	ClinGen ExAC gnomAD
rs766147135 CA6742340	882	E>K		No	ClinGen ExAC TOPMed gnomAD
rs754788380 CA6742342	884	A>V		No	ClinGen ExAC gnomAD
rs1332510569 CA386266763	885	A>G		No	ClinGen TOPMed gnomAD
rs201214965 CA6742346	885	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386266760 rs201214965	885	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742345 rs201214965	885	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742348 rs758522706	888	D>G		No	ClinGen ExAC gnomAD
CA6742347 rs745970567	888	D>H		No	ClinGen ExAC gnomAD
rs1346532020 CA386266804	889	E>K		No	ClinGen gnomAD
rs894595326 CA242176079	892	E>K		No	ClinGen Ensembl
rs768204318 CA242176086	894	E>G		No	ClinGen Ensembl
CA6742349 rs780222059	895	A>V		No	ClinGen ExAC gnomAD
rs768892597 CA6742351	896	V>A		No	ClinGen ExAC TOPMed gnomAD
rs781632334 CA6742352	897	P>L		No	ClinGen ExAC gnomAD
rs1189460510 CA386266926	898	Q>*		No	ClinGen gnomAD
rs772796121 CA6742355	899	D>G		No	ClinGen ExAC gnomAD
rs1277920756 CA386266977	901	S>Y		No	ClinGen TOPMed
rs200243638 CA386266998	903	Q>P		No	ClinGen 1000Genomes ExAC gnomAD
rs200243638 CA6742356	903	Q>R		No	ClinGen 1000Genomes ExAC gnomAD
CA6742357 rs770606237	905	K>E		No	ClinGen ExAC gnomAD
CA386267027 rs1565792287	905	K>R		No	ClinGen Ensembl
rs774141567 CA6742358	907	T>M		No	ClinGen ExAC TOPMed gnomAD
CA6742360 rs767156921	908	R>S		No	ClinGen ExAC TOPMed gnomAD
CA6742362 rs760481676	909	R>S		No	ClinGen ExAC TOPMed gnomAD
rs752569880 CA6742361	909	R>T		No	ClinGen ExAC TOPMed gnomAD
CA386267090 rs1369848970	910	A>G		No	ClinGen gnomAD
rs1302854275 CA386267113	912	A>G		No	ClinGen gnomAD
CA386267107 rs1373306271	912	A>T		No	ClinGen TOPMed
CA386267414 rs1390832161	913	K>N		No	ClinGen gnomAD
CA386267126 rs1332160486	913	K>R		No	ClinGen gnomAD
COSM933928 CA6742373 CA386267446 rs749876137	915	L>F	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs999865991 CA242177644	917	A>P		No	ClinGen TOPMed gnomAD
CA6742374 rs140037353	917	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs868699578 CA242177651	918	H>Y		No	ClinGen TOPMed gnomAD
rs771779384 CA6742377	920	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1224071947 CA386267501	920	Q>K		No	ClinGen gnomAD
CA6742376 rs759072687	920	Q>P		No	ClinGen ExAC gnomAD
CA6742379 rs376164687	921	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs201830409 CA6742381	925	F>V		No	ClinGen ExAC TOPMed gnomAD
rs1565792754 CA386267559	927	N>S		No	ClinGen Ensembl
CA386267569 rs761755493	929	R>G		No	ClinGen ExAC TOPMed gnomAD
CA6742383 rs370328018	929	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs370328018 CA6742384	929	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742382 rs761755493	929	R>W		No	ClinGen ExAC TOPMed gnomAD
rs752898415 CA6742387	937	L>P		No	ClinGen ExAC gnomAD
CA242177782 rs867868381	937	L>V		No	ClinGen Ensembl
CA6742388 rs756496096	938	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA6742389 rs778339439	939	E>K		No	ClinGen ExAC TOPMed gnomAD
CA386267671 rs778339439	939	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA6742390 rs200584245	941	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA386267725 rs1411037542	943	Q>*		No	ClinGen gnomAD
CA6742407 rs754279286	945	L>V		No	ClinGen ExAC gnomAD
CA386267894 rs1450610436	948	Q>E		No	ClinGen gnomAD
CA242178946 rs987315612	950	Q>R		No	ClinGen TOPMed
rs556321414 CA6742409	951	M>I		No	ClinGen 1000Genomes ExAC gnomAD
CA6742410 rs746429618	952	V>A		No	ClinGen ExAC gnomAD
CA386268008 rs1380755538	956	T>A		No	ClinGen gnomAD
rs757916667 CA6742411	958	D>G		No	ClinGen ExAC gnomAD
rs1434048136 CA386268056	960	I>V		No	ClinGen TOPMed
CA386268070 rs1343003202	961	M>I		No	ClinGen gnomAD
rs1228992762 CA386268081	963	Y>C		No	ClinGen TOPMed gnomAD
CA6742413 rs748782603	964	K>E		No	ClinGen ExAC gnomAD
TCGA novel	964	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386268096 rs1593431887	965	H>R		No	ClinGen Ensembl
CA6742415 rs200779998	966	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742414 rs768331170	966	P>S		No	ClinGen ExAC gnomAD
rs769612197 CA6742417	967	H>R		No	ClinGen ExAC gnomAD
rs747914213 CA6742416	967	H>Y		No	ClinGen ExAC gnomAD
CA6742418 rs773192305	968	V>I		No	ClinGen ExAC gnomAD
CA6742420 rs767575263	969	L>I		No	ClinGen ExAC gnomAD
CA6742421 rs775434089	970	P>T		No	ClinGen ExAC TOPMed gnomAD
rs113800459 CA242179019	972	R>W		No	ClinGen Ensembl
CA386268156 rs1245685411	973	E>D		No	ClinGen TOPMed gnomAD
rs1351691341 CA386268163	974	N>I		No	ClinGen gnomAD
rs749180327 CA6742438	976	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs749180327 CA386268173	976	Q>K		No	ClinGen ExAC TOPMed gnomAD
CA386268177 rs1593432110	976	Q>R		No	ClinGen Ensembl
rs1349853976 CA386268184	977	R>S		No	ClinGen gnomAD
rs899621964 CA242179363	977	R>W		No	ClinGen gnomAD
rs1593432119 CA386268212	981	D>V		No	ClinGen Ensembl
CA6742439 rs770803725	982	R>K		No	ClinGen ExAC TOPMed gnomAD
CA6742440 rs374755767	983	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1287074815 CA386268259	987	E>D		No	ClinGen gnomAD
rs768923842 CA6742442	988	I>V		No	ClinGen ExAC TOPMed gnomAD
CA386268266 rs1221724463	989	V>M		No	ClinGen TOPMed gnomAD
CA386268276 rs1482398063	990	H>R		No	ClinGen gnomAD
TCGA novel	991	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242179387 rs1026662161	993	I>V		No	ClinGen Ensembl
CA6742444 rs570614154	994	S>P		No	ClinGen 1000Genomes ExAC gnomAD
rs765574330 CA6742445	995	E>G		No	ClinGen ExAC TOPMed gnomAD
CA386268318 rs148536386	996	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742446 rs750787167	996	D>G		No	ClinGen ExAC gnomAD
CA242179406 rs993857773	996	D>Y		No	ClinGen TOPMed
CA386268338 rs1208114978	999	V>A		No	ClinGen TOPMed
rs539396900 CA6742448	999	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs142899095 CA6742450	1003	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs780734604 CA6742451	1004	H>R		No	ClinGen ExAC gnomAD
rs1034418436 CA242179453	1005	R>*		No	ClinGen TOPMed
CA6742452 rs367580506	1005	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs1309546233 CA386268383	1007	D>G		No	ClinGen TOPMed gnomAD
rs1309546233 CA386268384	1007	D>V		No	ClinGen TOPMed gnomAD
CA242179462 rs199725568	1011	I>V		No	ClinGen 1000Genomes TOPMed
rs749058167 CA6742455	1013	M>I		No	ClinGen ExAC gnomAD
rs1282040426 CA386268429	1014	R>T		No	ClinGen gnomAD
CA6742470 rs766829244 CA386268835	1016	L>F		No	ClinGen ExAC TOPMed gnomAD
rs577310747 CA6742472	1017	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
rs774823050 CA6742471	1017	Y>H		No	ClinGen ExAC gnomAD
rs1593434278 CA386269334 COSM1677282	1019	R>*	large_intestine [Cosmic]	No	ClinGen cosmic curated Ensembl
CA242183251 rs376327544	1019	R>L		No	ClinGen ExAC TOPMed gnomAD
CA6742474 rs376327544	1019	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1230613261 CA386269375	1022	N>Y		No	ClinGen gnomAD
CA386269400 rs1275951265	1023	K>N		No	ClinGen gnomAD
rs184835287 CA6742476	1025	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386269431 rs1199092478	1027	K>E		No	ClinGen TOPMed gnomAD
CA6742477 rs753594919	1028	T>S		No	ClinGen ExAC TOPMed
rs1281244944 CA386269447	1028	T>S		No	ClinGen gnomAD
rs756988988 CA6742478	1029	Q>L		No	ClinGen ExAC TOPMed gnomAD
CA386269463 rs756988988	1029	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs1416538703 CA386269468	1030	G>R		No	ClinGen TOPMed
CA6742479 rs778864851	1033	A>V		No	ClinGen ExAC gnomAD
rs745736302 CA6742480	1037	R>C		No	ClinGen ExAC TOPMed gnomAD
CA6742481 rs758445591	1037	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6742483 rs748156914	1038	M>V		No	ClinGen ExAC gnomAD
CA6742484 rs769953865	1039	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1412055124 CA386269527	1039	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs539567687 CA6742485	1040	I>V		No	ClinGen ExAC TOPMed gnomAD
CA6742486 rs749579850	1041	V>I		No	ClinGen ExAC gnomAD
rs774700772 CA6742488	1043	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6742487 rs771140706	1043	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA242183310 rs968642068	1046	A>S		No	ClinGen TOPMed gnomAD
rs1313571654 CA386269564	1046	A>V		No	ClinGen TOPMed
rs776025445 CA6742491	1047	G>R		No	ClinGen ExAC TOPMed gnomAD
rs760099420 CA6742492	1047	G>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1346173520 CA386269573	1048	T>I		No	ClinGen gnomAD
CA6742493 COSM318279 rs763717393	1048	T>S	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
TCGA novel	1049	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1266437305 CA386269579	1049	Q>R		No	ClinGen gnomAD
CA386269596 rs1209421135	1052	E>K		No	ClinGen gnomAD
rs375521157 CA6742495	1053	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742496 rs765087996	1054	Q>H		No	ClinGen ExAC gnomAD
rs1379103744 CA386269622	1055	I>M		No	ClinGen gnomAD
CA242183369 rs988484500	1055	I>V		No	ClinGen gnomAD
CA386269629 rs1459826678	1056	F>L		No	ClinGen TOPMed
rs954080236 CA242183370	1056	F>V		No	ClinGen TOPMed
CA6742497 rs576184899	1058	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386269639 rs1478221812	1058	D>H		No	ClinGen gnomAD
CA242183388 rs933891062	1061	F>S		No	ClinGen Ensembl
rs747030153 CA6742500	1063	P>L		No	ClinGen ExAC gnomAD
CA242183401 rs752063895	1066	H>P		No	ClinGen Ensembl
TCGA novel	1069	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1409759638 CA386269756	1073	H>R		No	ClinGen gnomAD
rs754945143 CA6742518	1079	A>E		No	ClinGen ExAC TOPMed gnomAD
CA386269797 rs754945143	1079	A>V		No	ClinGen ExAC TOPMed gnomAD
CA6742519 rs199951442	1081	E>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1220163644 CA386269806	1081	E>Q		No	ClinGen gnomAD
CA6742520 rs375681505	1082	D>N		No	ClinGen ESP ExAC gnomAD
CA6742522 rs376634646	1084	D>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742521 rs376634646	1084	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1247082410 CA386269836	1085	L>F		No	ClinGen gnomAD
CA386269846 rs1266173274	1087	K>*		No	ClinGen TOPMed gnomAD
CA386269845 rs1266173274	1087	K>E		No	ClinGen TOPMed gnomAD
rs1204358919 COSM545774 CA386269856	1088	V>G	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs746147073 CA6742523	1088	V>I		No	ClinGen ExAC TOPMed gnomAD
rs746147073 CA386269852	1088	V>L		No	ClinGen ExAC TOPMed gnomAD
rs578226793 CA6742524	1089	L>F		No	ClinGen 1000Genomes ExAC gnomAD
rs780474146 CA6742525	1090	P>L		No	ClinGen ExAC gnomAD
CA242185137 rs1033692405	1092	G>S		No	ClinGen TOPMed
COSM430157 CA386269877 rs1338509719	1092	G>V	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs552660501 CA6742527	1093	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
COSM1510355 CA6742529 rs142628447	1093	R>H	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs552660501 CA6742528	1093	R>S		No	ClinGen ExAC TOPMed gnomAD
CA242185169 rs755486538	1095	H>N		No	ClinGen gnomAD
rs769498323 CA386269898	1096	G>C		No	ClinGen ExAC TOPMed gnomAD
rs769498323 CA6742530	1096	G>S		No	ClinGen ExAC TOPMed gnomAD
CA6742531 rs772982542	1096	G>V		No	ClinGen ExAC gnomAD
CA6742532 rs762704658	1097	I>M		No	ClinGen ExAC gnomAD
CA6742533 rs766018627	1098	L>F		No	ClinGen ExAC gnomAD
CA6742535 rs759340911	1101	L>F		No	ClinGen ExAC gnomAD
CA386269938 rs1408172557	1102	E>G		No	ClinGen TOPMed
TCGA novel	1102	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386269948 rs1377234263	1103	I>M		No	ClinGen gnomAD
rs1159950495 CA386269946	1103	I>T		No	ClinGen TOPMed
rs12303732 CA242185192	1105	L>W		No	ClinGen Ensembl
CA386269976 rs1398022972	1106	K>E		No	ClinGen gnomAD
CA386269981 rs1565795352	1106	K>R		No	ClinGen Ensembl
rs1364591236 CA386270043	1110	H>L		No	ClinGen gnomAD
rs1226333526 CA386270066	1111	L>Q		No	ClinGen gnomAD
rs1272345098 CA386270077	1112	I>S		No	ClinGen gnomAD
TCGA novel	1112	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742538 rs757315993	1113	S>N		No	ClinGen ExAC TOPMed gnomAD
rs144955025 CA386270099	1113	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs750578552 COSM286421 CA6742540	1114	A>T	lung Variant assessed as Somatic; 4.623e-05 impact. large_intestine [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs780234831 CA6742542	1115	Y>S		No	ClinGen ExAC gnomAD
CA386270134 rs974996772	1116	L>V		No	ClinGen TOPMed
CA386270152 rs1186169759	1117	P>L		No	ClinGen TOPMed gnomAD
rs781721867 CA6742545	1119	I>V		No	ClinGen ExAC gnomAD
CA6742547 rs199815086	1123	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742546 rs199815086	1123	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1306594701 CA386270276	1124	L>F		No	ClinGen TOPMed gnomAD
rs748907134 CA6742549	1125	C>S		No	ClinGen ExAC TOPMed gnomAD
rs867223137 CA242185314	1126	M>T		No	ClinGen TOPMed
rs1303671520 CA386270311	1126	M>V		No	ClinGen gnomAD
rs1370266296 CA386270333	1127	T>A		No	ClinGen gnomAD
rs1388225206 CA386270364	1128	A>V		No	ClinGen gnomAD
COSM1322057 CA386270374 rs1355965089	1129	T>N	ovary Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA6742552 rs759344498	1130	V>I		No	ClinGen ExAC TOPMed gnomAD
CA386270410 rs1215092571	1132	H>R		No	ClinGen TOPMed gnomAD
CA242185383 rs908287297	1134	L>F		No	ClinGen Ensembl
rs775349192 CA6742554	1134	L>P		No	ClinGen ExAC gnomAD
TCGA novel	1136	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs939701786 CA242185385	1136	Q>R		No	ClinGen Ensembl
rs941358128 CA242185390	1137	R>*		No	ClinGen TOPMed gnomAD
CA242185418 rs757382700	1137	R>Q		No	ClinGen Ensembl
rs1482388741 CA386271357	1140	I>M		No	ClinGen gnomAD
CA6742568 rs774047938	1141	Q>R		No	ClinGen ExAC gnomAD
rs745522226 CA6742569	1142	L>M		No	ClinGen ExAC gnomAD
CA6742570 rs745522226	1142	L>V		No	ClinGen ExAC gnomAD
CA6742571 rs775297709	1144	F>I		No	ClinGen ExAC gnomAD
TCGA novel	1145	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742572 rs760557819	1147	P>L		No	ClinGen ExAC gnomAD
rs1183092145 CA386271399	1147	P>S		No	ClinGen gnomAD
CA6742574 rs776593176	1148	L>F		No	ClinGen ExAC gnomAD
CA6742575 rs150090423	1153	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742577 rs372292737	1153	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742576 rs150090423	1153	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1352238080 CA386271449	1155	G>R		No	ClinGen TOPMed
CA242188695 rs917181928	1156	I>F		No	ClinGen gnomAD
CA6742578 rs755156739	1156	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1409051300 CA386271462	1157	K>R		No	ClinGen TOPMed gnomAD
rs1404807430 CA386271470	1158	M>T		No	ClinGen gnomAD
rs376738828 CA386271476 CA6742579	1159	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs753132635 CA6742581	1161	D>G		No	ClinGen ExAC TOPMed gnomAD
rs753132635 CA6742580	1161	D>V		No	ClinGen ExAC TOPMed gnomAD
CA386271496 rs1406713277	1162	I>T		No	ClinGen gnomAD
rs778392441 CA6742582	1165	D>G		No	ClinGen ExAC gnomAD
rs749876191 CA6742583	1166	W>G		No	ClinGen ExAC gnomAD
CA386271532 rs1289814370	1167	E>A		No	ClinGen gnomAD
rs1174092723 CA386271555	1170	Q>R		No	ClinGen TOPMed
rs778291360 CA6742585	1176	I>V		No	ClinGen ExAC gnomAD
CA6742587 rs771646018	1181	H>R		No	ClinGen ExAC gnomAD
rs540510636 CA6742588	1182	G>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1378415528 CA386271642	1183	A>T		No	ClinGen TOPMed
CA386271652 rs1157471979	1184	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA6742590 rs768507897	1185	W>*		No	ClinGen ExAC gnomAD
CA6742589 rs746778315	1185	W>S		No	ClinGen ExAC gnomAD
CA6742613 rs138419405	1188	I>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1220790601 CA386271709	1190	R>W		No	ClinGen TOPMed gnomAD
CA6742615 rs148863398	1192	G>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs538134846 CA6742614	1192	G>R		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	1194	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742617 rs772343743	1195	S>G		No	ClinGen ExAC gnomAD
CA6742619 rs760990529	1198	S>F		No	ClinGen ExAC TOPMed gnomAD
CA386271832 rs760990529	1198	S>Y		No	ClinGen ExAC TOPMed gnomAD
rs1208470369 CA386271838	1199	P>A		No	ClinGen TOPMed
CA386271847 rs1485599938	1200	T>P		No	ClinGen TOPMed
TCGA novel	1201	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1344787741 CA386271873	1202	L>V		No	ClinGen TOPMed gnomAD
CA386271918 rs1461976819	1206	I>L		No	ClinGen gnomAD
CA386271927 rs1208115564	1206	I>M		No	ClinGen TOPMed gnomAD
CA386271980 rs1195280025	1209	W>C		No	ClinGen gnomAD
rs765632457 CA6742623	1209	W>R		No	ClinGen ExAC TOPMed gnomAD
CA386271996 rs1375802696	1210	S>R		No	ClinGen TOPMed
CA386272013 rs1373614146	1212	N>H		No	ClinGen gnomAD
CA386272019 rs1466353644	1212	N>S		No	ClinGen gnomAD
rs201748261 CA6742625	1213	A>T		No	ClinGen ExAC TOPMed gnomAD
CA242189742 rs918248387	1213	A>V		No	ClinGen TOPMed
rs747180221 CA386272699	1214	R>S		No	ClinGen ExAC
CA6742637 rs768978919	1215	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA386272704 rs768978919	1215	Y>F		No	ClinGen ExAC TOPMed gnomAD
rs1409359576 CA386272715	1217	P>T		No	ClinGen gnomAD
rs142641785 CA242192433	1218	L>*		No	ClinGen Ensembl
CA386272763 rs1478629957	1224	P>A		No	ClinGen gnomAD
CA242192438 rs200049376	1227	P>A		No	ClinGen Ensembl
rs762081637 CA386272793 CA6742639	1228	E>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC TOPMed gnomAD NCI-TCGA
CA6742640 rs765694981	1229	C>Y		No	ClinGen ExAC TOPMed gnomAD
CA6742642 rs763458770	1233	T>A		No	ClinGen ExAC gnomAD
rs567268708 CA242192494	1233	T>I		No	ClinGen TOPMed gnomAD
rs1180240270 CA386272832	1234	N>K		No	ClinGen TOPMed
CA386272835 rs1472573086	1235	V>I		No	ClinGen TOPMed
rs1319015338 CA386272841	1236	F>V		No	ClinGen gnomAD
rs1239855882 CA386272852	1237	A>V		No	ClinGen gnomAD
rs572010130 CA6742644	1238	I>V		No	ClinGen 1000Genomes ExAC gnomAD
CA6742645 rs185536134	1239	L>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA386272862 rs1220190241	1239	L>P		No	ClinGen gnomAD
rs1490442743 CA386272870	1241	A>T		No	ClinGen gnomAD
rs140749743 CA6742647 COSM300391	1241	A>V	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs777636821 CA6742649	1242	K>N		No	ClinGen ExAC gnomAD
rs1181835553 CA386272886	1243	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1181835553 CA386272885	1243	N>T		No	ClinGen TOPMed gnomAD
rs749171301 CA6742650	1244	L>F		No	ClinGen ExAC gnomAD
CA6742651 rs757282358	1244	L>P		No	ClinGen ExAC gnomAD
rs779044360 CA6742652	1245	S>A		No	ClinGen ExAC gnomAD
CA386272897 rs1317502247	1245	S>C		No	ClinGen TOPMed
rs1593438644 CA386272900	1246	D>H		No	ClinGen Ensembl
rs76793356 CA6742653	1248	T>P		No	ClinGen ExAC gnomAD
rs776706434 CA6742656	1251	I>N		No	ClinGen ExAC TOPMed gnomAD
CA6742655 rs776706434	1251	I>T		No	ClinGen ExAC TOPMed gnomAD
rs768849226 CA6742654	1251	I>V		No	ClinGen ExAC gnomAD
rs773660885 CA6742658	1253	M>I		No	ClinGen ExAC gnomAD
CA386272945 rs1390380556	1253	M>T		No	ClinGen TOPMed gnomAD
rs769989869 CA6742657	1253	M>V		No	ClinGen ExAC gnomAD
CA242192610 rs967879803	1254	D>H		No	ClinGen TOPMed gnomAD
CA386272949 rs967879803	1254	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs866519925 CA242192625	1255	I>T		No	ClinGen Ensembl
CA386272957 rs1248312715	1255	I>V		No	ClinGen gnomAD
CA6742659 rs138765948	1256	V>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742660 rs766846408	1257	D>G		No	ClinGen ExAC
rs1363457079 CA386272984	1259	L>F		No	ClinGen TOPMed
CA6742661 rs150082822	1261	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6742663 rs767111217	1266	E>K		No	ClinGen ExAC gnomAD
CA242192649 rs1030806628	1267	P>T		No	ClinGen Ensembl
rs1196052071 CA386273042	1268	T>A		No	ClinGen TOPMed gnomAD
rs752232067 CA6742664	1268	T>I		No	ClinGen ExAC TOPMed gnomAD
CA386273058 rs1404782074	1270	T>R		No	ClinGen TOPMed
rs1442219154 CA386273080	1273	N>K		No	ClinGen gnomAD
CA6742666 rs755795920	1275	L>V		No	ClinGen ExAC TOPMed gnomAD
CA242192658 rs990356408	1278	G>R		No	ClinGen TOPMed
CA6742667 rs763747390	1279	C>F		No	ClinGen ExAC gnomAD
rs1438476975 CA386273138	1280	V>I		No	ClinGen gnomAD
CA386273170 rs1245945771	1282	P>R		No	ClinGen TOPMed
CA386273163 rs1356663496	1282	P>S		No	ClinGen gnomAD
CA6742669 rs757159501	1283	G>D		No	ClinGen ExAC TOPMed gnomAD
rs1462651023 CA386273175	1283	G>S		No	ClinGen gnomAD
CA386273204 rs1565797679	1285	A>V		No	ClinGen Ensembl
rs1400392503 CA386273218	1286	E>D		No	ClinGen gnomAD
TCGA novel	1289	G>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386273279 rs1383347625	1289	G>D		No	ClinGen gnomAD
rs1315899970 CA386273269	1289	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs916319852 CA242193104	1290	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs781663541 CA242193141	1293	T>A		No	ClinGen Ensembl
CA6742697 rs188752585	1294	I>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA242193165 rs1043393547	1294	I>M		No	ClinGen TOPMed gnomAD
rs188752585 CA6742698	1294	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742696 rs777969594	1294	I>V		No	ClinGen ExAC gnomAD
CA386273423 rs1177384499	1295	G>E		No	ClinGen gnomAD
CA386273419 rs1471379656	1295	G>R		No	ClinGen gnomAD
rs779255929 CA6742699	1296	G>*		No	ClinGen ExAC gnomAD
rs746321279 CA6742700	1296	G>E		No	ClinGen ExAC TOPMed gnomAD
CA386273474 rs1291206605	1299	I>S		No	ClinGen TOPMed
rs1157520590 CA386273478	1300	L>I		No	ClinGen gnomAD
rs1052354356 CA242193205	1304	P>H		No	ClinGen Ensembl
rs1302250937 CA386273552	1305	A>G		No	ClinGen TOPMed gnomAD
rs768337638 CA6742704	1307	L>F		No	ClinGen ExAC gnomAD
CA6742706 rs761558757	1308	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs776362046 CA6742705	1308	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA6742707 rs765081808	1309	Y>N		No	ClinGen ExAC TOPMed gnomAD
CA6742708 rs750262301	1310	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1162426599 CA386273638	1312	K>E		No	ClinGen TOPMed
CA6742710 rs766313792	1312	K>R		No	ClinGen ExAC gnomAD
CA386273659 rs1424862602	1313	T>N		No	ClinGen TOPMed
CA242193260 rs997330377	1314	T>K		No	ClinGen Ensembl
rs1029110057 CA242193292	1315	I>K		No	ClinGen Ensembl
rs202205893 CA242193293	1317	A>T		No	ClinGen TOPMed gnomAD
CA386273716 rs1200676766	1318	E>A		No	ClinGen gnomAD
CA242193301 rs1006286472	1318	E>D		No	ClinGen Ensembl
rs1490937977 CA386273709	1318	E>K		No	ClinGen gnomAD
rs377526182 CA6742713	1321	K>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1322	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742714 rs753994001	1323	K>R		No	ClinGen ExAC TOPMed gnomAD
CA6742716 rs550961139	1326	R>G		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	1327	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746211908 CA6742717	1331	K>E		No	ClinGen ExAC gnomAD
rs1363688234 CA386273923	1333	L>F		No	ClinGen gnomAD
rs1363688234 CA386273920	1333	L>I		No	ClinGen gnomAD
CA6742718 rs758756100	1333	L>P		No	ClinGen ExAC TOPMed gnomAD
CA386273972 rs1439582444	1337	S>*		No	ClinGen gnomAD
rs1184164737 CA386253395	1338	K>N		No	ClinGen gnomAD
rs1373394579 CA386273988	1338	K>R		No	ClinGen gnomAD
CA6742746 rs140891740	1341	K>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242382683 rs767886502	1343	M>V		No	ClinGen TOPMed gnomAD
rs774046568 CA6742747	1345	D>N		No	ClinGen ExAC gnomAD
rs1368396871 CA386253636	1347	E>A		No	ClinGen gnomAD
TCGA novel	1347	E>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs972108450 CA242382693	1349	S>G		No	ClinGen TOPMed gnomAD
CA6742748 rs759421118	1350	S>C		No	ClinGen ExAC gnomAD
COSM1232151 CA6742749 rs767420759	1354	T>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1325262697 CA386253787	1357	L>F		No	ClinGen gnomAD
CA6742753 rs750590866	1360	L>F		No	ClinGen ExAC gnomAD
CA6742754 rs561334023 COSM318280	1362	R>C	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC gnomAD
CA6742755 rs766714525	1362	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6742756 rs766714525	1362	R>P		No	ClinGen ExAC gnomAD
rs866289187 CA242382759	1363	G>D		No	ClinGen Ensembl
rs781764519 CA6742758	1364	N>D		No	ClinGen ExAC gnomAD
CA386253882 rs1260956614	1364	N>S		No	ClinGen gnomAD
CA386253899 rs1488338074	1365	I>V		No	ClinGen TOPMed
CA6742759 rs147946096	1366	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs980921290 CA242382763	1367	E>Q		No	ClinGen TOPMed
CA386255460 rs1206857481	1368	D>G		No	ClinGen TOPMed gnomAD
CA6742774 rs759970064	1370	E>D		No	ClinGen ExAC TOPMed gnomAD
rs751900429 CA6742773	1370	E>V		No	ClinGen ExAC gnomAD
rs768010423 CA386255517	1371	V>A		No	ClinGen ExAC TOPMed gnomAD
CA6742775 rs768010423	1371	V>G		No	ClinGen ExAC TOPMed gnomAD
rs73378743 CA6742777	1373	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs753191987 COSM1726787 CA6742776	1373	I>V	liver [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA386255560 rs1180389641	1374	L>V		No	ClinGen gnomAD
rs1593440345 CA386255580	1375	V>E		No	ClinGen Ensembl
rs887139548 CA242384034	1378	Q>E		No	ClinGen Ensembl
TCGA novel	1378	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1378	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1365558701 CA386255709	1382	K>N		No	ClinGen gnomAD
CA386255706 rs1159619354	1382	K>T		No	ClinGen gnomAD
CA386255719 rs1235400055	1383	H>R		No	ClinGen TOPMed
rs1593440360 CA386255751	1386	D>A		No	ClinGen Ensembl
CA6742780 rs368387710	1387	P>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742782 rs142061094	1387	P>H		No	ClinGen ESP ExAC gnomAD
rs142061094 CA6742781	1387	P>R		No	ClinGen ESP ExAC gnomAD
CA6742783 rs771786212	1388	T>A		No	ClinGen ExAC gnomAD
TCGA novel	1389	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1004157912 CA242384049	1389	S>T		No	ClinGen Ensembl
CA386255814 rs1593440373	1391	L>H		No	ClinGen Ensembl
rs577001413 CA6742784	1394	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742785 rs753635463	1396	K>N		No	ClinGen ExAC TOPMed gnomAD
CA6742786 rs768453138	1397	L>P		No	ClinGen ExAC gnomAD
rs528536715 CA242384066	1401	I>L		No	ClinGen TOPMed
rs1488572886 CA386255944	1401	I>T		No	ClinGen gnomAD
rs528536715 CA386255937	1401	I>V		No	ClinGen TOPMed
CA6742788 rs376859385	1403	N>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA6742790 rs201836633	1404	K>R		No	ClinGen 1000Genomes ExAC
CA386256001 rs1248025038	1405	L>S		No	ClinGen TOPMed gnomAD
CA386256002 rs1248025038	1405	L>W		No	ClinGen TOPMed gnomAD
CA6742791 rs759845191	1406	S>L		No	ClinGen ExAC gnomAD
rs1396708382 CA386256077	1411	C>Y		No	ClinGen TOPMed
rs200766524 CA6742792	1412	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1462698861 CA386256138	1416	T>A		No	ClinGen gnomAD
rs774607968 CA6742811	1416	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1404041133 CA386256143	1417	L>V		No	ClinGen TOPMed gnomAD
CA242384233 rs1014025305	1418	S>F		No	ClinGen TOPMed
CA386256172 rs1345634315	1419	D>E		No	ClinGen TOPMed
rs746040572 CA386256161	1419	D>H		No	ClinGen ExAC gnomAD
rs746040572 CA6742812	1419	D>N		No	ClinGen ExAC gnomAD
CA386256224 rs775896086	1423	G>E		No	ClinGen ExAC TOPMed gnomAD
rs772403943 CA6742813	1423	G>R		No	ClinGen ExAC TOPMed gnomAD
CA6742814 rs775896086	1423	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1381379174 CA386256239	1425	K>E		No	ClinGen gnomAD
rs760944434 CA6742815	1425	K>N		No	ClinGen ExAC gnomAD
CA242384262 rs758050270	1426	Y>C		No	ClinGen TOPMed gnomAD
rs908634267 CA242384267	1427	I>M		No	ClinGen TOPMed gnomAD
CA386256273 rs1421011577	1427	I>T		No	ClinGen TOPMed
CA386256269 rs1218899485	1427	I>V		No	ClinGen TOPMed gnomAD
CA386256282 rs1486384928	1428	T>A		No	ClinGen TOPMed
CA6742817 rs776935849	1429	D>A		No	ClinGen ExAC TOPMed gnomAD
CA386256320 rs776935849	1429	D>G		No	ClinGen ExAC TOPMed gnomAD
CA386256332 rs1468264630	1430	V>I		No	ClinGen Ensembl
CA386256374 rs1485829070	1432	K>T		No	ClinGen gnomAD
rs1362442754 CA386256457	1433	L>V		No	ClinGen gnomAD
rs765891022 CA6742843	1435	A>T		No	ClinGen ExAC gnomAD
CA242384378 rs751110666 CA386256521	1436	F>L		No	ClinGen ExAC TOPMed gnomAD
CA6742846 rs767171002	1437	D>G		No	ClinGen ExAC gnomAD
CA6742845 rs759266823	1437	D>N		No	ClinGen ExAC TOPMed gnomAD
CA6742847 rs752516463	1438	Q>E		No	ClinGen ExAC
TCGA novel	1438	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1371944008 CA386256587	1439	R>T		No	ClinGen gnomAD
rs1221621538 CA386256613	1440	H>P		No	ClinGen gnomAD
rs1355128164 CA386256660	1442	D>G		No	ClinGen gnomAD
rs777849689 CA6742850	1443	D>E		No	ClinGen ExAC gnomAD
CA6742848 rs756016136	1443	D>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs976824098 CA242384406	1443	D>N		No	ClinGen TOPMed gnomAD
rs1222548828 CA386256694	1444	I>N		No	ClinGen TOPMed gnomAD
CA386256697 rs1222548828	1444	I>T		No	ClinGen TOPMed gnomAD
rs199880162 CA6742853	1447	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs768900064 COSM170545 CA6742854	1448	V>I	large_intestine Variant assessed as Somatic; 9.241e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs781306759 CA6742855	1449	R>C		No	ClinGen ExAC TOPMed gnomAD
rs1383187013 CA386256788	1449	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA242384473 rs113934134	1451	E>G		No	ClinGen Ensembl
rs748505632 CA6742856	1452	T>I		No	ClinGen ExAC gnomAD
rs1405620826 CA386256856	1453	F>S		No	ClinGen gnomAD
rs145374811 CA6742857	1454	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs773648684 CA6742858	1456	I>V		No	ClinGen ExAC
CA6742859 rs202225479	1457	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386256912 rs1332795173	1458	S>F		No	ClinGen gnomAD
CA386256918 rs1378239261	1459	Y>N		No	ClinGen gnomAD
rs773936722 CA6742861	1460	I>V		No	ClinGen ExAC gnomAD
CA386256946 rs1362013723	1461	K>E		No	ClinGen gnomAD
rs1322610138 CA386256989	1464	Q>P		No	ClinGen TOPMed gnomAD
CA242384513 rs983432198 CA386257013	1466	V>L		No	ClinGen TOPMed gnomAD
rs967135903 CA242384520	1467	D>E		No	ClinGen Ensembl
rs759019749 CA6742863	1467	D>G		No	ClinGen ExAC gnomAD
CA386257078 rs1458125051	1471	L>P		No	ClinGen gnomAD
CA6742867 rs763994847	1475	M>I		No	ClinGen ExAC TOPMed gnomAD
CA386257170 rs1418263566	1478	C>Y		No	ClinGen gnomAD
rs1172144810 CA386257179	1479	F>I		No	ClinGen TOPMed gnomAD
COSM1232152 CA6742868 rs753785975	1479	F>L	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA6742869 rs374268906	1480	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1335301064 CA386257230	1482	L>Q		No	ClinGen gnomAD
rs1342855511 CA386257245	1483	E>D		No	ClinGen gnomAD
CA386257645 rs1325013944	1486	D>G		No	ClinGen gnomAD
rs201044694 CA6742884	1487	M>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs763931199 CA6742885	1488	S>N		No	ClinGen ExAC TOPMed gnomAD
CA6742886 rs776545622	1491	D>G		No	ClinGen ExAC TOPMed gnomAD
rs765762378 CA6742887	1492	N>S		No	ClinGen ExAC gnomAD
rs765212475 CA6742888	1494	S>N		No	ClinGen ExAC TOPMed gnomAD
CA242385552 rs765212475	1494	S>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1497	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742891 rs767496063	1498	M>T		No	ClinGen ExAC gnomAD
CA6742890 rs755025031	1498	M>V		No	ClinGen ExAC gnomAD
rs778022967 CA6742894	1501	I>M		No	ClinGen ExAC TOPMed
CA6742893 rs539094192	1501	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6742896 rs757630101	1504	L>P		No	ClinGen ExAC gnomAD
CA386257774 rs1196592044	1505	A>P		No	ClinGen gnomAD
CA6742897 rs779462884	1506	A>V		No	ClinGen ExAC gnomAD
rs746376511 CA6742898	1508	N>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1509	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742900 rs146459370	1509	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1299194093 CA386257807	1510	T>R		No	ClinGen gnomAD
rs775161803 CA6742901	1511	E>A		No	ClinGen ExAC TOPMed gnomAD
CA386257828 rs1403359604	1513	D>G		No	ClinGen gnomAD
CA386257842 rs1331733432	1515	R>K		No	ClinGen gnomAD
rs923095333 CA242385619	1516	E>*		No	ClinGen TOPMed gnomAD
rs556113854 CA6742903	1518	I>V		No	ClinGen 1000Genomes ExAC gnomAD
rs11614935 CA242385620	1519	H>P		No	ClinGen Ensembl
rs140971531 CA6742904	1520	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs117417637 CA6742905	1520	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA242385637 rs117417637 COSM3700178	1520	R>L	liver [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
rs200304349 CA6742906	1522	L>F		No	ClinGen 1000Genomes ExAC gnomAD
rs762833409 CA6742908	1524	E>K		No	ClinGen ExAC TOPMed gnomAD
rs762833409 CA386257893	1524	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs1314518166 CA386257897	1524	E>V		No	ClinGen Ensembl
CA386257905 rs1451659088	1525	K>R		No	ClinGen gnomAD
rs1362498186 CA386257949	1529	G>V		No	ClinGen gnomAD
rs764296748 CA6742912	1532	S>G		No	ClinGen ExAC gnomAD
CA6742913 rs754118365	1533	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6742914 rs757585781	1534	T>R		No	ClinGen ExAC TOPMed gnomAD
CA386258073 rs1243132182	1536	S>N		No	ClinGen gnomAD
rs769589007 CA6742925	1537	I>V		No	ClinGen ExAC TOPMed gnomAD
CA386258123 rs1369215771	1540	D>V		No	ClinGen gnomAD
CA242386169 rs1015154195	1542	T>A		No	ClinGen TOPMed
rs1461696490 CA386258152	1542	T>N		No	ClinGen gnomAD
CA386258162 rs1447512117	1543	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs139881043 CA6742926	1544	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs368175517 CA386258187	1546	S>A		No	ClinGen 1000Genomes ESP ExAC TOPMed
CA6742927 rs368175517	1546	S>P		No	ClinGen 1000Genomes ESP ExAC TOPMed
CA6742928 rs770829524	1547	C>F		No	ClinGen ExAC gnomAD
CA386258214 rs1267193737	1548	L>S		No	ClinGen gnomAD
CA386258231 rs1300048218	1550	Q>E		No	ClinGen gnomAD
CA386258233 rs1300048218	1550	Q>K		No	ClinGen gnomAD
rs774343283 CA6742929	1551	T>I		No	ClinGen ExAC gnomAD
TCGA novel	1551	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742930 rs548640606	1552	F>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1264785850 CA386258275	1554	N>D		No	ClinGen TOPMed
CA386258301 rs1393998877	1556	L>V		No	ClinGen TOPMed gnomAD
rs1221493725 CA386258310	1557	E>Q		No	ClinGen gnomAD
CA386258352 rs1314627438	1560	D>N		No	ClinGen gnomAD
rs1488613822 CA386258378	1562	V>L		No	ClinGen TOPMed
rs764173740 CA6742931	1565	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	1566	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs960490555 CA242386200	1566	H>Y		No	ClinGen TOPMed gnomAD
rs992310505 CA242386203	1568	H>R		No	ClinGen Ensembl
rs144785642 CA6742933	1572	M>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs138618335 CA242386215	1573	D>H		No	ClinGen ESP TOPMed
rs1262992004 CA386258588	1574	F>L		No	ClinGen gnomAD
rs1482570821 CA386258623	1575	F>L		No	ClinGen gnomAD
CA386258682 rs1183917193	1578	M>I		No	ClinGen TOPMed gnomAD
CA242386217 rs534543110	1580	H>Q		No	ClinGen 1000Genomes
rs1338811213 CA386258715	1580	H>Y		No	ClinGen Ensembl
rs1322998782 CA386258734	1581	I>T		No	ClinGen TOPMed
rs765543488 CA6742934	1581	I>V		No	ClinGen ExAC gnomAD
rs1428336742 CA386258749	1582	Q>R		No	ClinGen gnomAD
CA386258865 rs765373209	1583	I>S		No	ClinGen ExAC TOPMed gnomAD
CA6742953 rs765373209	1583	I>T		No	ClinGen ExAC TOPMed gnomAD
CA386258857 rs1302196265	1583	I>V		No	ClinGen gnomAD
rs1383687438 CA386258955	1589	A>V		No	ClinGen Ensembl
rs1030652195 CA242386787	1593	L>F		No	ClinGen TOPMed gnomAD
TCGA novel	1593	L>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742956 rs766850977	1594	A>G		No	ClinGen ExAC gnomAD
rs1488716489 CA386259028	1595	K>R		No	ClinGen gnomAD
rs1221984289 CA386259042	1596	Q>R		No	ClinGen gnomAD
CA386259069 rs1425715866	1598	M>T		No	ClinGen gnomAD
CA386259062 rs1191851831	1598	M>V		No	ClinGen gnomAD
CA6742957 rs752070046	1600	G>D		No	ClinGen ExAC gnomAD
CA6742959 rs149336135	1603	V>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs367941748 CA6742960	1604	L>V		No	ClinGen ESP ExAC gnomAD
rs777281225 CA6742962	1606	S>Y		No	ClinGen ExAC TOPMed gnomAD
CA386259200 rs1365289231	1608	S>F		No	ClinGen TOPMed
rs756979304 CA386259205	1609	L>F		No	ClinGen ExAC TOPMed gnomAD
CA386259209 rs1423116818	1609	L>P		No	ClinGen TOPMed
rs756979304 CA6742964	1609	L>V		No	ClinGen ExAC TOPMed gnomAD
rs778713790 CA6742965	1610	Q>H		No	ClinGen ExAC gnomAD
CA6742966 rs745758873	1614	M>I		No	ClinGen ExAC
CA386259264 rs1445256995	1615	P>S		No	ClinGen gnomAD
CA6742967 rs771964399	1616	Y>C		No	ClinGen ExAC gnomAD
rs1312147742 CA386259269	1616	Y>H		No	ClinGen gnomAD
CA242386921 rs1029074136	1617	A>S		No	ClinGen TOPMed gnomAD
rs1287911608 CA386259279	1617	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA386259296 rs1323746921	1620	P>A		No	ClinGen gnomAD
rs1323746921 CA386259297	1620	P>S		No	ClinGen gnomAD
rs1222335366 CA386259303	1621	I>V		No	ClinGen gnomAD
rs1456536811 CA386259320	1623	D>G		No	ClinGen gnomAD
rs1232406484 CA386259316	1623	D>N		No	ClinGen gnomAD
rs1456536811 CA386259321	1623	D>V		No	ClinGen gnomAD
rs1463191340 CA386259327	1624	E>G		No	ClinGen TOPMed
CA242386929 rs986388533	1624	E>K		No	ClinGen TOPMed gnomAD
CA6742968 rs775562299	1625	K>R		No	ClinGen ExAC gnomAD
rs200660845 CA6742969	1627	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1390137775 CA386260525	1629	H>Q		No	ClinGen TOPMed
rs1259833257 CA386260522	1629	H>R		No	ClinGen gnomAD
rs199793716 CA6742982	1633	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1635	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1637	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6742985 rs758246406	1638	E>D		No	ClinGen ExAC gnomAD
CA386260603 rs1182060868	1639	I>V		No	ClinGen gnomAD
CA242390251 rs918519737	1640	I>T		No	ClinGen TOPMed gnomAD
rs779797414 CA6742986	1642	A>T		No	ClinGen ExAC gnomAD
COSM32703 VAR_036274 CA6742987 rs140657361	1645	K>I	breast a breast cancer sample; somatic mutation [Cosmic, UniProt]	No	ClinGen cosmic curated UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA6742988 rs769717548	1645	K>N		No	ClinGen ExAC TOPMed gnomAD
rs1414433334 CA386260647	1646	H>N		No	ClinGen gnomAD
rs1414433334 CA386260649	1646	H>Y		No	ClinGen gnomAD
rs1435638396 CA386260666	1648	S>F		No	ClinGen TOPMed
rs375635027 CA242390265	1649	W>L		No	ClinGen ESP TOPMed gnomAD
rs184720709 CA6742989	1651	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242390274 rs184720709	1651	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1277806435 CA386260708	1652	Y>C		No	ClinGen gnomAD
CA386260726 rs1565801797	1653	M>T		No	ClinGen Ensembl
rs771250173 CA6742991	1653	M>V		No	ClinGen ExAC gnomAD
CA6742994 rs767941739	1656	L>S		No	ClinGen ExAC TOPMed gnomAD
CA6742993 rs759969869	1656	L>V		No	ClinGen ExAC gnomAD
rs1199772212 CA386260782	1657	K>R		No	ClinGen gnomAD
CA386260789 rs775793754	1658	H>N		No	ClinGen ExAC TOPMed gnomAD
rs775793754 CA6742995	1658	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA386260810 rs1443914250	1659	F>S		No	ClinGen gnomAD
rs763464301 CA6742997	1661	H>R		No	ClinGen ExAC gnomAD
rs753325126 CA6742998	1665	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs77578150 CA6743000	1666	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242390302 rs537785440	1669	N>H		No	ClinGen TOPMed gnomAD
rs556112079 CA242390304	1669	N>S		No	ClinGen TOPMed gnomAD
CA6743001 rs750088372	1673	G>A		No	ClinGen ExAC gnomAD
rs1212612075 CA386261014	1676	L>F		No	ClinGen gnomAD
rs764731370 CA6743022	1679	I>V		No	ClinGen ExAC gnomAD
CA386261092 rs1390371648	1685	H>Y		No	ClinGen gnomAD
rs750032755 CA6743023	1687	D>E		No	ClinGen ExAC gnomAD
CA242390797 rs867243698	1687	D>N		No	ClinGen Ensembl
CA386261149 rs1391753731	1688	H>Q		No	ClinGen TOPMed
rs762685426 CA6743024	1688	H>Y		No	ClinGen ExAC gnomAD
rs765993610 CA6743025	1690	T>I		No	ClinGen ExAC TOPMed gnomAD
rs562904840 CA242390808	1691	L>P		No	ClinGen 1000Genomes
rs751335167 CA6743027	1694	Q>L		No	ClinGen ExAC TOPMed gnomAD
CA6743028 rs373208716	1698	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1702	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242391673 rs772682870	1704	A>S		No	ClinGen ExAC TOPMed gnomAD
rs772682870 CA6743044	1704	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1339467483 CA386261646	1704	A>V		No	ClinGen gnomAD
rs762406678 CA6743045	1705	I>T		No	ClinGen ExAC gnomAD
rs1050847513 CA242391678	1705	I>V		No	ClinGen TOPMed gnomAD
CA6743046 rs766047935	1708	I>V		No	ClinGen ExAC
rs773936056 CA6743047	1709	E>A		No	ClinGen ExAC TOPMed gnomAD
rs773936056 CA6743048	1709	E>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1715	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386261825 rs1459490674	1717	E>*		No	ClinGen gnomAD
rs759446787 CA242391697	1719	E>Q		No	ClinGen Ensembl
rs1196699046 CA386261868	1720	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs756143997 CA6743051	1720	R>H		No	ClinGen ExAC TOPMed gnomAD
CA386261874 rs756143997 COSM3810782	1720	R>P	breast [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs764176723 CA6743052	1722	D>V		No	ClinGen ExAC gnomAD
CA386261923 rs1285890174	1724	E>Q		No	ClinGen TOPMed
rs750486862 CA6743053	1725	E>A		No	ClinGen ExAC gnomAD
rs1226298360 CA386261991	1728	Y>H		No	ClinGen TOPMed
rs758462757 CA6743054	1729	T>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1397969450 CA386262051	1730	C>Y		No	ClinGen gnomAD
rs1565802612 CA386262064	1731	K>E		No	ClinGen Ensembl
CA6743057 rs776367536	1732	S>N		No	ClinGen ExAC TOPMed gnomAD
rs776367536 CA386262099	1732	S>T		No	ClinGen ExAC TOPMed gnomAD
rs1346558162 CA386262116	1733	L>*		No	ClinGen Ensembl
rs1363560163 CA386262181	1736	N>H		No	ClinGen TOPMed
rs1394130991 CA386262192	1736	N>S		No	ClinGen TOPMed gnomAD
CA242391737 rs868446613	1737	G>R		No	ClinGen gnomAD
rs138643360 CA6743059	1739	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386262251 rs1565802631	1739	P>S		No	ClinGen Ensembl
CA386262303 rs1319436791	1742	P>A		No	ClinGen gnomAD
rs1014340936 CA242391743	1742	P>L		No	ClinGen TOPMed
CA6743062 rs773656267	1743	D>N		No	ClinGen ExAC gnomAD
rs1049360452 CA242391765	1744	P>A		No	ClinGen TOPMed
CA386262364 rs1482480147	1745	A>V		No	ClinGen gnomAD
CA386262367 rs1403432291	1746	D>N		No	ClinGen gnomAD
CA682724591 rs1405053064	1748	G>N		No	ClinGen TOPMed
rs1446259644 CA386262414	1749	G>E		No	ClinGen TOPMed
CA386262448 rs1258423462	1752	A>D		No	ClinGen gnomAD
rs1593446066 CA386262457	1753	K>E		No	ClinGen Ensembl
rs1488101471 CA386262463	1753	K>I		No	ClinGen gnomAD
CA6743065 rs773991609	1754	E>Q		No	ClinGen ExAC gnomAD
CA386262506 rs1171039688	1756	E>D		No	ClinGen gnomAD
rs537149110 CA6743067	1756	E>K		No	ClinGen ExAC TOPMed gnomAD
CA386262531 rs1390790093	1758	I>N		No	ClinGen TOPMed gnomAD
rs775403795 CA6743068	1759	T>K		No	ClinGen ExAC TOPMed gnomAD
rs760587520 CA6743069	1760	K>T		No	ClinGen ExAC gnomAD
rs764125310 CA6743070	1762	V>F		No	ClinGen ExAC gnomAD
CA6743071 rs764125310	1762	V>I		No	ClinGen ExAC gnomAD
CA386262622 rs1399046537	1765	L>I		No	ClinGen gnomAD
rs201687062 CA6743073	1769	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA386262686 rs1214716769	1769	K>T		No	ClinGen gnomAD
CA386262697 rs1301109383	1770	E>K		No	ClinGen gnomAD
CA6743074 rs751752396	1772	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs370227791 CA6743075	1775	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1235823719 CA386262749	1775	T>S		No	ClinGen gnomAD
CA242391814 rs957622751	1776	I>S		No	ClinGen gnomAD
rs1214693483 CA386262760	1777	K>E		No	ClinGen gnomAD
rs1368112919 CA386262779	1779	I>T		No	ClinGen gnomAD
CA386262785 rs1220737843	1780	Q>P		No	ClinGen TOPMed gnomAD
rs781431203 CA6743076	1781	G>E		No	ClinGen ExAC gnomAD
TCGA novel	1782	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748505798 CA6743077	1782	T>P		No	ClinGen ExAC gnomAD
rs1190687504 CA386262798	1782	T>S		No	ClinGen TOPMed gnomAD
rs1434611335 CA386262801	1783	I>V		No	ClinGen Ensembl
rs202007555 CA6743080	1784	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386262811 rs1273094961	1784	T>I		No	ClinGen TOPMed
CA6743082 rs770436107	1785	G>R		No	ClinGen ExAC TOPMed gnomAD
rs770436107 CA386262813	1785	G>W		No	ClinGen ExAC TOPMed gnomAD
rs745423859 CA6743084	1786	D>V		No	ClinGen ExAC gnomAD
CA386262826 rs1593446151	1787	I>F		No	ClinGen Ensembl
rs1565802736 CA386262847	1790	R>K		No	ClinGen Ensembl
rs1203143200 CA386262854	1791	L>P		No	ClinGen gnomAD
rs143164886 CA6743088	1796	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242391851 rs964359460	1796	A>S		No	ClinGen Ensembl
rs966475727 CA242391861	1797	S>F		No	ClinGen TOPMed gnomAD
CA6743089 rs776588186	1798	T>M		No	ClinGen ExAC TOPMed gnomAD
CA6743090 rs776588186	1798	T>R		No	ClinGen ExAC TOPMed gnomAD
rs761708682 CA6743108	1799	T>A		No	ClinGen ExAC TOPMed gnomAD
rs769612786 CA6743109	1800	K>E		No	ClinGen ExAC gnomAD
CA6743110 rs773190450	1800	K>T		No	ClinGen ExAC gnomAD
CA386263768 rs1457280701	1801	R>G		No	ClinGen gnomAD
CA242394509 rs1006661189	1801	R>K		No	ClinGen TOPMed gnomAD
rs764430407 CA6743115	1809	K>T		No	ClinGen ExAC gnomAD
CA6743116 rs754125503	1810	S>L		No	ClinGen ExAC gnomAD
CA6743118 rs779277196	1811	K>N		No	ClinGen ExAC gnomAD
rs1464549657 CA386263842	1811	K>R		No	ClinGen gnomAD
CA6743119 rs750967262	1815	D>H		No	ClinGen ExAC gnomAD
rs779728964 CA6743121	1817	E>D		No	ClinGen ExAC gnomAD
CA6743120 rs76752752	1817	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743124 rs768218728	1819	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6743125 COSM933941 rs747880391	1820	R>*	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA386263899 rs769642275	1820	R>L		No	ClinGen ExAC gnomAD
rs769642275 CA6743126	1820	R>Q		No	ClinGen ExAC gnomAD
CA386263900 rs1216693636	1821	V>I		No	ClinGen gnomAD
TCGA novel	1824	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743127 rs201154660	1826	A>P		No	ClinGen ExAC gnomAD
rs201154660 CA242394568	1826	A>T		No	ClinGen ExAC gnomAD
rs1235332298 CA386263936	1826	A>V		No	ClinGen gnomAD
CA6743130 rs775525025	1827	M>I		No	ClinGen ExAC gnomAD
CA242394581 rs773807111	1827	M>K		No	ClinGen ExAC TOPMed gnomAD
rs773807111 CA6743129	1827	M>T		No	ClinGen ExAC TOPMed gnomAD
rs749256675 CA6743128	1827	M>V		No	ClinGen ExAC TOPMed gnomAD
CA6743132 rs377746179	1828	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743131 rs377746179	1828	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1414204246 CA386263954	1830	L>I		No	ClinGen TOPMed gnomAD
CA386263955 rs1414204246	1830	L>V		No	ClinGen TOPMed gnomAD
rs1377460808 CA386263972	1832	Q>L		No	ClinGen gnomAD
rs776973416 CA6743133	1834	L>P		No	ClinGen ExAC TOPMed gnomAD
CA242394589 rs756356391	1837	E>Q		No	ClinGen Ensembl
CA6743134 rs762028396	1838	V>I		No	ClinGen ExAC TOPMed gnomAD
CA6743136 rs750908440	1839	M>I		No	ClinGen ExAC gnomAD
CA6743135 rs765662675	1839	M>T		No	ClinGen ExAC TOPMed gnomAD
CA242394590 rs545662193	1839	M>V		No	ClinGen 1000Genomes gnomAD
CA386264027 rs1302850358	1841	A>T		No	ClinGen TOPMed
CA6743137 rs200642215	1842	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA386264119 rs1284307677	1846	I>V		No	ClinGen gnomAD
TCGA novel	1847	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1450586058 CA386264192	1849	K>E		No	ClinGen gnomAD
CA386264226 rs773676126	1850	V>A		No	ClinGen ExAC gnomAD
CA6743155 rs773676126	1850	V>G		No	ClinGen ExAC gnomAD
rs1197349017 CA386264218	1850	V>M		No	ClinGen gnomAD
rs1593446999 CA386264239	1851	C>S		No	ClinGen Ensembl
CA6743156 rs763477546	1851	C>S		No	ClinGen ExAC gnomAD
CA6743157 rs190550846	1852	A>T		No	ClinGen 1000Genomes ExAC gnomAD
CA386264268 rs1471299477 COSM1232155	1852	A>V	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA6743158 rs367575502	1853	L>P		No	ClinGen ESP ExAC gnomAD
rs754377144 CA6743159	1854	L>F		No	ClinGen ExAC TOPMed gnomAD
rs752244186 CA6743161	1858	A>T		No	ClinGen ExAC gnomAD
CA386264411 rs1396614350	1860	E>K		No	ClinGen gnomAD
rs1335092276 CA386264453	1861	I>M		No	ClinGen TOPMed
CA6743162 rs755769682	1861	I>T		No	ClinGen ExAC gnomAD
rs777443406 CA6743163	1863	D>E		No	ClinGen ExAC gnomAD
CA386264491 rs1468193712	1863	D>Y		No	ClinGen gnomAD
rs757105753 CA6743165	1864	I>T		No	ClinGen ExAC gnomAD
CA6743164 rs749081214	1864	I>V		No	ClinGen ExAC TOPMed gnomAD
CA6743166 rs778767258 COSM430160	1866	R>C	Variant assessed as Somatic; 0.0 impact. large_intestine breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs371374289 CA6743167	1866	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1275538070 CA386264551	1870	A>E		No	ClinGen TOPMed gnomAD
rs1275538070 CA386264553	1870	A>V		No	ClinGen TOPMed gnomAD
CA386264560 rs1198366616	1871	K>N		No	ClinGen gnomAD
rs748212074 CA6743170	1873	I>T		No	ClinGen ExAC gnomAD
rs781307701 CA6743169	1873	I>V		No	ClinGen ExAC TOPMed gnomAD
CA6743171 rs770132309	1875	D>G		No	ClinGen ExAC TOPMed gnomAD
rs1471817742 CA386264589	1876	L>I		No	ClinGen gnomAD
rs1471817742 CA386264590	1876	L>V		No	ClinGen gnomAD
CA386264632 rs10082778	1882	L>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_055136 CA6743173 rs10082778	1882	L>Q		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA386264631 rs10082778	1882	L>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1330644770 CA386264646	1884	V>A		No	ClinGen gnomAD
rs1392984466 CA386264668	1887	E>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs374794776 CA6743177	1889	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743178 rs752220287	1890	T>A		No	ClinGen ExAC TOPMed gnomAD
CA386264690 rs1382720819	1891	T>A		No	ClinGen TOPMed
rs760245089 CA6743179	1891	T>S		No	ClinGen ExAC TOPMed gnomAD
CA386264695 rs1593447113	1892	L>V		No	ClinGen Ensembl
rs763725976 CA6743180	1894	R>C		No	ClinGen ExAC TOPMed gnomAD
CA386264707 rs763725976	1894	R>G		No	ClinGen ExAC TOPMed gnomAD
rs753504875 CA6743181	1894	R>H		No	ClinGen ExAC TOPMed
CA6743183 rs778788547	1896	Y>H		No	ClinGen ExAC gnomAD
rs750232665 CA386264730	1897	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1317960400 CA386264728	1897	Q>L		No	ClinGen TOPMed
CA6743193 rs759858291	1898	V>I		No	ClinGen ExAC gnomAD
rs1255736818 CA386265233	1901	L>V		No	ClinGen gnomAD
rs775922525 CA386265251	1902	T>A		No	ClinGen ExAC TOPMed gnomAD
CA6743195 rs775922525	1902	T>P		No	ClinGen ExAC TOPMed gnomAD
rs775922525 CA242397924	1902	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1201199611 CA386265293	1904	T>A		No	ClinGen TOPMed
CA386265305 rs1593449109	1904	T>I		No	ClinGen Ensembl
rs76643734 RCV000879079 CA6743197	1905	V>I		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA386265333 rs1290202929	1906	H>D		No	ClinGen gnomAD
CA6743199 rs761429859	1914	N>D		No	ClinGen ExAC gnomAD
CA6743200 rs764835175	1914	N>S		No	ClinGen ExAC TOPMed gnomAD
rs376472973 CA6743201	1918	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743203 rs779982797	1919	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs12309241 CA386265607	1921	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242397983 rs950096600	1921	L>W		No	ClinGen gnomAD
CA386265623 rs1175125950	1922	D>H		No	ClinGen gnomAD
CA6743205 rs756221544	1923	S>F		No	ClinGen ExAC gnomAD
rs565059952 CA6743206	1924	C>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1237482838 CA386265681	1926	D>H		No	ClinGen gnomAD
rs1363503291 CA386265686	1926	D>V		No	ClinGen gnomAD
rs749429613 CA6743207	1927	I>T		No	ClinGen ExAC gnomAD
CA386265714 rs1369227332	1928	M>T		No	ClinGen TOPMed gnomAD
CA386265706 rs1301253079	1928	M>V		No	ClinGen gnomAD
CA242399116 rs998844009	1931	I>M		No	ClinGen gnomAD
CA6743222 rs200676365	1931	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA386265860 rs1481098287	1933	N>K		No	ClinGen TOPMed
RCV000885823 CA6743223 rs79904445	1934	H>R		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1408387304 CA386265873	1935	E>G		No	ClinGen gnomAD
CA386265912 rs1328287343	1941	A>T		No	ClinGen gnomAD
rs1215529686 CA386265929	1943	E>G		No	ClinGen gnomAD
rs766116806 CA6743224	1944	K>N		No	ClinGen ExAC gnomAD
CA6743225 rs548762458	1945	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs1175113596 CA386265942	1945	E>V		No	ClinGen gnomAD
CA386265962 rs1383695558	1948	Q>*		No	ClinGen gnomAD
TCGA novel	1948	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743227 rs767605228	1950	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1275523044 CA386265987	1952	K>E		No	ClinGen TOPMed
rs568702973 CA6743230	1954	M>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386266011 rs1327226475	1955	E>A		No	ClinGen TOPMed gnomAD
CA6743231 rs746086197	1956	A>T		No	ClinGen ExAC gnomAD
rs758751810 CA6743232	1956	A>V		No	ClinGen ExAC gnomAD
rs780421838 CA6743233 COSM933944	1957	R>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs747411596 CA6743234	1957	R>Q		No	ClinGen ExAC gnomAD
rs1284424760 CA386266029	1958	R>S		No	ClinGen TOPMed
CA386266031 rs1225916509	1959	S>G		No	ClinGen TOPMed
CA6743235 rs534493086	1960	K>E		No	ClinGen 1000Genomes ExAC gnomAD
rs1348670510 CA386266050	1961	S>I		No	ClinGen TOPMed
rs1348670510 CA386266048	1961	S>N		No	ClinGen TOPMed
COSM79095 CA6743238 rs747596099	1962	Y>*	ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs761861027 CA6743239	1963	D>E		No	ClinGen ExAC TOPMed gnomAD
CA386266061 rs867034932	1963	D>H		No	ClinGen gnomAD
rs867034932 CA242399189	1963	D>N		No	ClinGen gnomAD
rs867034932 CA386266060	1963	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6743240 rs762533237	1964	S>A		No	ClinGen ExAC gnomAD
CA386266067 rs762533237	1964	S>P		No	ClinGen ExAC gnomAD
CA919159451 rs1593449772	1965	Y>*		No	ClinGen Ensembl
CA6743241 rs766103136	1965	Y>H		No	ClinGen ExAC gnomAD
rs1565805218 CA386266090	1967	I>T		No	ClinGen Ensembl
TCGA novel	1968	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743243 rs759472914	1969	G>C		No	ClinGen ExAC TOPMed gnomAD
COSM1358145 CA6743244 rs759472914	1969	G>S	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA386266107 rs1470933938	1970	K>R		No	ClinGen TOPMed
rs1475938209 CA386266116	1971	F>S		No	ClinGen gnomAD
CA386266123 rs1419431423	1972	V>A		No	ClinGen gnomAD
rs750611754 CA386266140	1975	D>H		No	ClinGen ExAC TOPMed gnomAD
CA6743248 rs750611754	1975	D>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1976	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1976	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1355295570 CA386266150	1976	Q>R		No	ClinGen gnomAD
CA386266161 rs1461113732	1978	T>A		No	ClinGen TOPMed
rs141173458 CA6743249 RCV000885824	1979	K>E		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs908921210 CA242399297	1979	K>R		No	ClinGen gnomAD
rs1415479382 CA386266173	1980	L>V		No	ClinGen TOPMed gnomAD
rs1361206414 CA386266202	1983	P>S		No	ClinGen gnomAD
CA6743253 rs142320995	1985	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA386266251 rs1209694154	1986	E>D		No	ClinGen gnomAD
rs1593449829 CA386266247	1986	E>G		No	ClinGen Ensembl
rs201490996 CA6743278	1988	L>V		No	ClinGen 1000Genomes ExAC gnomAD
rs367851970 CA242400709	1989	Q>L		No	ClinGen ESP TOPMed gnomAD
CA6743279 rs146367811	1990	N>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs747940559 CA6743280	1992	T>M		No	ClinGen ExAC TOPMed gnomAD
CA6743285 rs139139597	1998	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743284 COSM1232149 rs766476346	1998	R>W	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1334039209 CA386266593	1999	K>E		No	ClinGen TOPMed
CA6743286 rs759731933	2001	H>D		No	ClinGen ExAC TOPMed gnomAD
CA242400761 rs948183973	2001	H>R		No	ClinGen Ensembl
rs1038084042 CA242400762	2002	E>A		No	ClinGen TOPMed gnomAD
CA386266640 rs1038084042	2002	E>G		No	ClinGen TOPMed gnomAD
CA386266656 rs1362288476	2003	T>S		No	ClinGen TOPMed gnomAD
CA6743287 rs143153802 COSM1561888	2005	R>C	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs143153802 CA6743288	2005	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs756559736 CA6743289	2005	R>H		No	ClinGen ExAC TOPMed gnomAD
rs756559736 CA6743290	2005	R>L		No	ClinGen ExAC TOPMed gnomAD
CA6743291 rs754376370	2006	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs756791850 COSM1358146 CA6743292	2006	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA242400810 rs907097284	2012	I>V		No	ClinGen TOPMed
CA242400823 rs771907975	2014	N>K		No	ClinGen Ensembl
CA6743297 rs758097426	2015	Q>*		No	ClinGen ExAC gnomAD
CA386266826 rs1387138993	2017	M>V		No	ClinGen gnomAD
rs1327698488 CA386266868	2020	E>K		No	ClinGen gnomAD
rs1257644076 CA386266886	2021	S>P		No	ClinGen TOPMed
rs779811047 CA6743300	2021	S>Y		No	ClinGen ExAC gnomAD
CA386266898 rs1443687740	2022	I>F		No	ClinGen gnomAD
CA6743301 rs746719745	2022	I>S		No	ClinGen ExAC gnomAD
CA386266901 rs746719745	2022	I>T		No	ClinGen ExAC gnomAD
TCGA novel	2023	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386266921 rs1565805774	2024	L>S		No	ClinGen Ensembl
TCGA novel	2027	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242400871 rs1029548418	2027	Y>N		No	ClinGen Ensembl
CA386266976 rs1487678584	2028	G>D		No	ClinGen TOPMed
CA386267003 rs1275677714	2030	I>S		No	ClinGen gnomAD
rs953880159 CA242400881	2030	I>V		No	ClinGen TOPMed gnomAD
rs1195605108 CA386267022	2031	S>R		No	ClinGen gnomAD
rs1357419098 CA6743305	2031	S>R		No	ClinGen TOPMed gnomAD
CA386267028 rs1248634656	2032	E>K		No	ClinGen gnomAD
CA242400910 rs1034990688	2035	P>L		No	ClinGen TOPMed gnomAD
CA242400902 rs1034990688	2035	P>R		No	ClinGen TOPMed gnomAD
CA6743308 rs776389782	2038	T>P		No	ClinGen ExAC gnomAD
CA6743309 rs776389782	2038	T>S		No	ClinGen ExAC gnomAD
CA386267127 rs1419953921	2040	K>E		No	ClinGen gnomAD
CA386267137 rs1458176673	2040	K>N		No	ClinGen gnomAD
rs772200066 CA6743333	2043	N>S		No	ClinGen ExAC gnomAD
CA386267181 rs1328562245	2044	P>L		No	ClinGen gnomAD
rs1304078142 CA386267197	2047	P>Q		No	ClinGen gnomAD
rs760983038 CA6743335	2048	A>V		No	ClinGen ExAC TOPMed gnomAD
rs777108135 CA6743337	2050	D>E		No	ClinGen ExAC TOPMed gnomAD
rs762337652 CA6743338	2052	R>C		No	ClinGen ExAC gnomAD
CA6743339 rs200987450	2052	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1317060038 CA386267236	2054	P>Q		No	ClinGen gnomAD
CA386267243 rs1258941768	2055	P>L		No	ClinGen gnomAD
CA6743341 rs369147512	2055	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743343 rs751078144	2056	Q>H		No	ClinGen ExAC gnomAD
rs765933027 CA6743342	2056	Q>R		No	ClinGen ExAC gnomAD
rs1452153122 CA386267251	2057	S>G		No	ClinGen gnomAD
TCGA novel	2058	C>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs947252322 CA242401826	2059	L>F		No	ClinGen TOPMed
CA386267280 rs1377686565	2061	L>P		No	ClinGen gnomAD
CA242401856 rs933726574	2062	P>T		No	ClinGen Ensembl
TCGA novel	2063	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1565806049 CA386267287	2063	P>S		No	ClinGen Ensembl
rs373946150 CA6743347	2064	T>S		No	ClinGen ESP ExAC gnomAD
CA386267303 rs1387803210	2065	P>L		No	ClinGen gnomAD
rs1436224340 CA386267311	2067	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs777621371 CA6743349	2067	R>P		No	ClinGen ExAC TOPMed gnomAD
rs777621371 CA6743348	2067	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1210241748 CA386267313	2068	G>S		No	ClinGen gnomAD
rs780163654 CA6743351	2069	G>E		No	ClinGen ExAC gnomAD
CA6743352 rs747101880	2072	A>S		No	ClinGen ExAC TOPMed gnomAD
CA242401894 rs942303087	2073	V>L		No	ClinGen TOPMed
rs768922754 CA6743353	2074	V>G		No	ClinGen ExAC gnomAD
rs1393688301 CA386267363	2076	R>G		No	ClinGen TOPMed
CA6743354 rs777054847	2076	R>T		No	ClinGen ExAC TOPMed gnomAD
rs1466227031 CA386267379	2078	T>N		No	ClinGen TOPMed gnomAD
CA6743355 rs762198453	2078	T>S		No	ClinGen ExAC TOPMed gnomAD
rs1209327683 CA386267386	2079	N>S		No	ClinGen gnomAD
CA386267391 rs1593451011	2080	M>V		No	ClinGen Ensembl
CA386267422 rs1467016299	2082	I>M		No	ClinGen gnomAD
CA6743356 rs377393735	2082	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA386267430 rs1490904654	2083	F>Y		No	ClinGen TOPMed gnomAD
TCGA novel	2084	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386267439 rs1192567844	2084	I>V		No	ClinGen gnomAD
CA386267462 rs1197613106	2085	E>D		No	ClinGen TOPMed gnomAD
rs1417950513 CA386267484	2087	G>A		No	ClinGen gnomAD
rs139993869 CA6743359	2089	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368816848 CA6743358	2089	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1187769913 CA386267631	2092	H>L		No	ClinGen gnomAD
rs1416350837 CA386267652	2094	S>N		No	ClinGen gnomAD
rs1165970202 CA386267720	2099	K>R		No	ClinGen gnomAD
rs540667932 CA6743372	2100	I>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs540667932 CA242402957	2100	I>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs540667932 CA386267730	2100	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	2102	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743374 rs566317967	2105	E>D		No	ClinGen ExAC gnomAD
rs773678254 CA6743375	2110	M>V		No	ClinGen ExAC gnomAD
CA386267818 rs1414253848	2112	D>Y		No	ClinGen gnomAD
CA6743377 rs180913369	2113	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386267850 rs1353516040	2115	V>L		No	ClinGen gnomAD
rs1446755889 CA386267881	2117	L>R		No	ClinGen TOPMed
CA386267888 rs1290299896	2118	L>F		No	ClinGen TOPMed gnomAD
rs139860197 CA6743380	2119	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242403074 rs867384052	2124	S>F		No	ClinGen Ensembl
rs117476305 CA6743381 RCV000957672	2128	K>R		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA386268461 rs1163282535	2132	G>S		No	ClinGen gnomAD
CA386268476 rs1416819823	2134	L>S		No	ClinGen TOPMed
rs145553624 CA6743408	2135	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs977857106 CA242404761	2136	C>*		No	ClinGen Ensembl
CA386268488 rs1593452383	2136	C>R		No	ClinGen Ensembl
rs1334670287 CA386268502	2138	I>V		No	ClinGen gnomAD
CA386268535 rs1432589311	2142	R>S		No	ClinGen gnomAD
CA6743411 rs142621773	2144	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA386268559 rs1272789747	2146	P>L		No	ClinGen gnomAD
CA386268554 rs1181643591	2146	P>T		No	ClinGen TOPMed
CA6743414 rs749504475	2148	I>T		No	ClinGen ExAC gnomAD
CA386268581 rs1258312028	2150	T>A		No	ClinGen TOPMed
CA386268584 rs1213679753	2150	T>I		No	ClinGen TOPMed
CA386268589 rs1284127014	2151	K>T		No	ClinGen gnomAD
rs532458001 CA6743415	2152	A>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	2152	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743416 rs779125530	2153	E>G		No	ClinGen ExAC gnomAD
rs759751947 CA242404823	2154	Q>R		No	ClinGen Ensembl
CA242404825 rs368586505	2157	K>E		No	ClinGen ESP TOPMed
rs887618091 CA242404826	2158	H>N		No	ClinGen Ensembl
rs753723276 CA6743418	2158	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1310236420 CA386268668	2164	K>E		No	ClinGen TOPMed
CA6743419 rs146353954	2164	K>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs746467924 CA6743420	2167	A>G		No	ClinGen ExAC gnomAD
rs1478368080 CA386268690	2167	A>T		No	ClinGen gnomAD
CA242404839 rs990604941	2169	L>P		No	ClinGen TOPMed
CA6743423 rs372898217	2170	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA386268716 rs1161357834	2171	A>D		No	ClinGen gnomAD
rs141629518 CA6743425	2172	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs150422308 CA6743426 RCV000903319	2173	R>G		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs751546746 CA6743428	2175	Q>R		No	ClinGen ExAC gnomAD
rs1278420231 CA386268757	2177	F>L		No	ClinGen gnomAD
CA6743429 rs760797743	2177	F>L		No	ClinGen ExAC gnomAD
rs11615135 CA242404919	2178	H>P		No	ClinGen Ensembl
rs1565806957 CA386268760	2178	H>Y		No	ClinGen Ensembl
CA6743431 rs138226932	2179	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA242404927 rs138226932	2179	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743432 rs754000492	2181	V>F		No	ClinGen ExAC gnomAD
CA6743433 rs149603349	2182	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs75031616 CA242404945	2182	N>Y		No	ClinGen 1000Genomes
TCGA novel	2184	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242404994 rs144338772	2185	K>R		No	ClinGen ESP TOPMed
CA6743445 rs562091153	2186	C>Y		No	ClinGen 1000Genomes ExAC gnomAD
rs1471708181 CA386268851	2187	V>M		No	ClinGen TOPMed
rs1272759174 CA386268859	2188	T>I		No	ClinGen gnomAD
rs774383044 CA6743446	2190	L>F		No	ClinGen ExAC gnomAD
rs767532247 CA6743448	2191	V>I		No	ClinGen ExAC gnomAD
TCGA novel	2194	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1462264044 CA386268906	2195	K>N		No	ClinGen TOPMed
rs753860891 CA6743449	2198	Q>E		No	ClinGen ExAC TOPMed gnomAD
CA6743450 rs762013459	2198	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA6743451 rs765322230	2199	I>T		No	ClinGen ExAC gnomAD
TCGA novel	2202	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386268981 rs1368337868	2206	V>D		No	ClinGen gnomAD
rs1269662887 CA386268995	2209	A>S		No	ClinGen TOPMed
CA6743453 rs369865286	2210	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1565807141 CA386269012	2211	A>V		No	ClinGen Ensembl
TCGA novel	2212	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	2213	E>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1356151015 CA386269029	2214	D>N		No	ClinGen TOPMed
CA6743456 rs755432902	2218	T>S		No	ClinGen ExAC gnomAD
CA6743459 rs747551809 CA6743458	2219	S>*		No	ClinGen ExAC gnomAD
CA6743460 rs747551809	2219	S>L		No	ClinGen ExAC gnomAD
rs781750460 CA6743457	2219	S>T		No	ClinGen ExAC gnomAD
rs1295621149 CA386269068	2220	R>G		No	ClinGen gnomAD
CA6743461 rs748970812	2220	R>K		No	ClinGen ExAC gnomAD
rs770757513 CA6743462	2221	Q>K		No	ClinGen ExAC gnomAD
CA386269076 rs1279681269	2221	Q>R		No	ClinGen gnomAD
CA386269082 rs1482355052	2222	A>P		No	ClinGen gnomAD
CA6743464 rs745713661	2223	T>I		No	ClinGen ExAC gnomAD
rs774258450 CA6743463	2223	T>P		No	ClinGen ExAC gnomAD
TCGA novel	2225	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs201141140 CA6743465	2226	G>A		No	ClinGen ExAC gnomAD
rs766523697 CA6743489	2231	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1318449487 CA386269155	2232	L>S		No	ClinGen TOPMed
rs1322772093 CA386269165	2234	R>G		No	ClinGen Ensembl
rs774571712 CA6743490	2234	R>T		No	ClinGen ExAC gnomAD
rs759771736 CA6743491	2235	K>Q		No	ClinGen ExAC TOPMed gnomAD
CA386269181 rs1227708285	2236	L>P		No	ClinGen gnomAD
CA386269194 rs1330876766	2238	V>A		No	ClinGen gnomAD
CA6743494 rs180780749	2239	P>L		No	ClinGen 1000Genomes ExAC gnomAD
CA242406084 rs766100227	2242	D>G		No	ClinGen Ensembl
CA242406103 rs753771405	2245	M>T		No	ClinGen gnomAD
CA6743499 rs778647982	2246	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA6743497 rs753392000	2246	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA386269256 rs1458054936	2248	V>I		No	ClinGen gnomAD
rs1348552915 CA386269263	2249	S>P		No	ClinGen gnomAD
rs758085666 CA6743501	2249	S>Y		No	ClinGen ExAC gnomAD
CA6743502 rs142287605	2253	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743504 rs768579024	2257	S>N		No	ClinGen ExAC gnomAD
rs372457025 CA6743506	2258	E>K	Variant assessed as Somatic; 4.622e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs372457025 CA386269333	2258	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs774397930 CA6743508	2259	P>R		No	ClinGen ExAC gnomAD
rs771023694 CA6743507	2259	P>S		No	ClinGen ExAC gnomAD
rs771023694 CA386269344	2259	P>T		No	ClinGen ExAC gnomAD
CA386269356 rs759773189	2260	A>P		No	ClinGen ExAC gnomAD
CA6743509 rs759773189	2260	A>S		No	ClinGen ExAC gnomAD
rs772232264 CA6743510	2262	V>F		No	ClinGen ExAC TOPMed gnomAD
rs772232264 CA386269378	2262	V>I		No	ClinGen ExAC TOPMed gnomAD
rs775909500 CA6743511	2263	Q>*		No	ClinGen ExAC gnomAD
CA6743512 rs761186850	2263	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA6743513 rs764628008	2264	C>R		No	ClinGen ExAC TOPMed gnomAD
CA6743514 rs754408117	2264	C>Y		No	ClinGen ExAC TOPMed gnomAD
rs376562450 CA6743531	2268	F>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs762374363 CA6743532	2273	L>I		No	ClinGen ExAC gnomAD
CA6743533 rs765726286	2274	D>E		No	ClinGen ExAC
rs139827671 CA6743534	2275	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA386270146 rs1390863865	2282	R>K		No	ClinGen gnomAD
rs1441560158 CA386270164	2283	P>L		No	ClinGen TOPMed
CA386270172 rs1413987690	2284	N>D		No	ClinGen gnomAD
TCGA novel	2285	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs762377711 CA6743535	2285	L>W		No	ClinGen ExAC gnomAD
CA386270209 rs1357388069	2286	E>A		No	ClinGen gnomAD
rs766002145 CA6743536	2287	F>L		No	ClinGen ExAC gnomAD
CA6743538 rs754729985	2288	M>L		No	ClinGen ExAC TOPMed gnomAD
rs767269641 CA6743539	2293	N>H		No	ClinGen ExAC gnomAD
CA6743556 rs759167711	2294	Y>H		No	ClinGen ExAC gnomAD
CA242409794 rs1024283589	2295	E>K		No	ClinGen TOPMed gnomAD
CA242409804 rs143189050	2296	H>R		No	ClinGen ESP TOPMed gnomAD
CA386270506 rs1411179830	2297	E>Q		No	ClinGen gnomAD
rs1198690136 CA386270550	2300	R>T		No	ClinGen TOPMed
CA6743561 rs753738063	2301	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs1321254830 CA386270586	2303	T>I		No	ClinGen gnomAD
rs758462810 CA6743562	2304	L>*		No	ClinGen ExAC gnomAD
rs1032802610 CA242409852	2308	A>T		No	ClinGen TOPMed gnomAD
CA6743567 rs139095183	2309	Y>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242409879 rs988527920	2309	Y>N		No	ClinGen Ensembl
CA386270650 rs139095183	2309	Y>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743568 rs149930556	2310	L>F		No	ClinGen ESP ExAC TOPMed
rs1333312155 CA386270672	2311	F>S		No	ClinGen TOPMed
CA6743570 rs749729594	2312	D>E		No	ClinGen ExAC gnomAD
rs1292308588 CA386270679	2312	D>G		No	ClinGen gnomAD
TCGA novel	2312	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386270676 rs1208216424	2312	D>N		No	ClinGen TOPMed gnomAD
rs771517719 CA6743571	2313	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1377953817 CA386270714	2315	P>L		No	ClinGen TOPMed
rs1482021096 CA386270710	2315	P>S		No	ClinGen gnomAD
rs773838973 CA6743572	2316	Q>*		No	ClinGen ExAC gnomAD
CA6743573 rs759112591	2316	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs775080807 CA6743593	2320	H>N		No	ClinGen ExAC TOPMed gnomAD
CA6743594 rs760211652	2320	H>R		No	ClinGen ExAC TOPMed gnomAD
rs199641573 CA6743595	2322	N>S		No	ClinGen 1000Genomes ExAC
COSM933948 CA6743597 rs142260891	2324	G>R	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD
CA386270838 rs1434644685	2325	M>T		No	ClinGen TOPMed gnomAD
rs765212844 CA6743598	2326	F>L		No	ClinGen ExAC TOPMed gnomAD
CA6743600 rs759652491	2329	P>R		No	ClinGen ExAC gnomAD
CA6743599 rs750411580	2329	P>S		No	ClinGen ExAC gnomAD
rs1593454211 CA386270901	2331	C>S		No	ClinGen Ensembl
CA242410049 rs1001374064	2332	L>R		No	ClinGen TOPMed
rs752872426 CA6743602	2334	T>A		No	ClinGen ExAC gnomAD
CA6743603 rs756277930	2334	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1461606141 CA386270946	2336	N>D		No	ClinGen TOPMed gnomAD
CA386270948 rs1461606141	2336	N>H		No	ClinGen TOPMed gnomAD
rs778124444 CA6743604	2336	N>S		No	ClinGen ExAC TOPMed gnomAD
rs778124444 CA6743605	2336	N>T		No	ClinGen ExAC TOPMed gnomAD
CA386270962 rs1193237067	2337	D>G		No	ClinGen gnomAD
rs1035562508 CA242410097	2337	D>N		No	ClinGen TOPMed gnomAD
rs369003885 COSM933949 CA6743606	2341	T>M	endometrium [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA6743608 rs746404453	2343	K>R		No	ClinGen ExAC gnomAD
rs1593454250 CA386271047	2345	M>T		No	ClinGen Ensembl
rs779515157 CA6743610	2348	M>I		No	ClinGen ExAC TOPMed gnomAD
CA242410159 rs1045343901	2348	M>V		No	ClinGen gnomAD
rs746583770 CA6743611	2351	K>N		No	ClinGen ExAC gnomAD
TCGA novel	2352	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743612 rs768185494	2354	L>H		No	ClinGen ExAC gnomAD
rs905440750 CA242410180	2355	G>C		No	ClinGen Ensembl
rs1230886146 CA386271163	2357	I>V		No	ClinGen gnomAD
CA386271173 rs1264940897	2358	S>G		No	ClinGen gnomAD
CA6743615 rs769744992 COSM415674	2360	E>K	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1205416221 CA386271233	2363	D>N		No	ClinGen TOPMed gnomAD
CA386271244 rs1332571860	2364	W>G		No	ClinGen TOPMed
rs80165298 CA242410200	2366	F>V		No	ClinGen Ensembl
rs762963021 CA6743617	2367	D>H		No	ClinGen ExAC gnomAD
CA6743619 rs201064625	2368	M>K		No	ClinGen ExAC gnomAD
CA6743618 rs766484215	2368	M>V		No	ClinGen ExAC TOPMed gnomAD
rs750012163 CA242410231	2370	T>I		No	ClinGen Ensembl
TCGA novel	2371	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386271289 rs1430642569	2371	T>P		No	ClinGen gnomAD
CA386271303 rs1157361537	2372	W>C		No	ClinGen gnomAD
CA386271336 rs1565808163	2377	K>R		No	ClinGen Ensembl
rs760622502 COSM1232154 CA6743638	2378	R>C	Variant assessed as Somatic; 0.0003698 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs573079112 CA6743641	2378	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs573079112 CA6743640	2378	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6743639 rs760622502	2378	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1370094219 CA386271733	2380	N>T		No	ClinGen gnomAD
rs147856864 CA6743642	2381	R>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs758763001 CA6743644	2384	A>G		No	ClinGen ExAC gnomAD
rs1033522898 CA242410959	2386	L>V		No	ClinGen Ensembl
rs766750923 CA6743645	2387	I>M		No	ClinGen ExAC gnomAD
CA6743646 rs752142725	2390	L>F		No	ClinGen ExAC TOPMed gnomAD
rs80101191 CA6743647	2392	V>L		No	ClinGen ExAC gnomAD
CA386271889 rs1203553747	2393	E>G		No	ClinGen gnomAD
CA386271911 rs780734087	2394	S>R		No	ClinGen ExAC gnomAD
CA6743649 rs747719423	2395	E>G		No	ClinGen ExAC gnomAD
CA386271948 rs1433615981	2397	V>A		No	ClinGen TOPMed
CA386271950 rs1433615981	2397	V>G		No	ClinGen TOPMed
CA6743652 rs376302667	2397	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	2398	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770779908 CA6743653	2402	R>I		No	ClinGen ExAC gnomAD
TCGA novel	2402	R>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386272024 rs1427921457	2403	L>F		No	ClinGen gnomAD
rs1168176507 CA386272051	2405	T>S		No	ClinGen gnomAD
CA386272075 rs1398625171	2409	V>M		No	ClinGen TOPMed
rs1301989774 CA386272084	2410	I>T		No	ClinGen gnomAD
rs200541979 CA242411035	2411	E>G		No	ClinGen 1000Genomes gnomAD
rs200541979 CA386272090	2411	E>V		No	ClinGen 1000Genomes gnomAD
rs199846837 CA242411042	2413	E>G		No	ClinGen 1000Genomes
CA242411051 rs967143108	2414	I>T		No	ClinGen TOPMed
CA6743658 rs761945531	2418	N>D		No	ClinGen ExAC gnomAD
rs769933960 CA6743659	2420	K>R		No	ClinGen ExAC gnomAD
CA6743681 rs545303599	2423	M>L		No	ClinGen 1000Genomes ExAC gnomAD
CA386272189 rs1242776766	2423	M>T		No	ClinGen gnomAD
rs1477775640 CA386272200	2424	E>D		No	ClinGen gnomAD
rs773322137 CA6743682	2425	E>G		No	ClinGen ExAC TOPMed gnomAD
rs1464178766 CA386272227	2428	E>G		No	ClinGen gnomAD
TCGA novel	2432	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743684 COSM278062 rs771120382	2433	R>C	upper_aerodigestive_tract Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA6743685 rs147796377	2433	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386272292 rs1387654240	2438	F>V		No	ClinGen gnomAD
CA6743686 rs759824701	2440	T>I		No	ClinGen ExAC gnomAD
rs768012945 CA6743687	2441	L>P		No	ClinGen ExAC gnomAD
CA6743688 rs753280046	2442	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1330714932 CA386272332	2444	K>N		No	ClinGen gnomAD
rs760221379 CA6743689	2446	I>T		No	ClinGen ExAC TOPMed gnomAD
CA386272349 rs1156515622	2447	K>R		No	ClinGen TOPMed
CA386272369 rs1407477803	2450	N>H		No	ClinGen TOPMed gnomAD
VAR_036275	2452	I>F	a breast cancer sample; somatic mutation [UniProt]	No	UniProt
TCGA novel	2453	Q>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763664877 CA6743690	2454	F>Y		No	ClinGen ExAC TOPMed gnomAD
CA6743691 rs370248060	2455	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1288050832 CA386272410	2455	T>P		No	ClinGen gnomAD
rs375433227 CA242411567	2457	P>L		No	ClinGen ESP TOPMed
rs994190333 CA242411568	2458	A>T		No	ClinGen TOPMed
CA386272522 rs1285283930	2465	W>*		No	ClinGen gnomAD
CA242414051 rs898458244	2466	S>N		No	ClinGen Ensembl
rs377707855 CA6743704	2466	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1047284531 CA242414087	2467	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs143659522 CA6743705	2469	H>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1249790153 CA386273334	2474	H>Q		No	ClinGen gnomAD
rs1223117007 CA386273329	2474	H>Y		No	ClinGen gnomAD
CA6743706 rs147638083	2479	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	2487	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA242414099 rs1001252343	2488	G>R		No	ClinGen TOPMed gnomAD
TCGA novel	2489	L>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386273518 rs1424805824	2490	L>F		No	ClinGen gnomAD
CA6743708 rs761241707	2493	S>F		No	ClinGen ExAC gnomAD
rs371378555 CA6743709	2498	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1329897712 CA386273641	2499	L>V		No	ClinGen TOPMed gnomAD
CA242414106 rs756326544	2500	I>F		No	ClinGen Ensembl
CA386273654 rs1340254085	2500	I>T		No	ClinGen gnomAD
CA6743710 rs776272918	2501	Q>K		No	ClinGen ExAC gnomAD
CA6743711 rs761229316	2501	Q>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA242414108 rs780186819	2503	W>G		No	ClinGen gnomAD
CA6743712 rs116332299	2504	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA242414119 rs1020137666	2505	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1337308543 CA386273742	2506	K>R		No	ClinGen gnomAD
rs955245576 CA386273761	2507	K>N		No	ClinGen gnomAD
CA386273757 rs1171377743	2507	K>R		No	ClinGen gnomAD
rs1593456695 CA386273764	2508	T>P		No	ClinGen Ensembl
CA6743715 rs766142512	2510	K>N		No	ClinGen ExAC TOPMed gnomAD
CA386273807 rs1273359798	2511	H>D		No	ClinGen gnomAD
rs1593456703 CA386273811	2511	H>P		No	ClinGen Ensembl
rs1593456711 CA386273829	2512	L>P		No	ClinGen Ensembl
CA242414151 rs987143491	2513	P>L		No	ClinGen TOPMed
rs1593456717 CA386273856	2514	E>D		No	ClinGen Ensembl
rs373837810 CA6743717	2514	E>V		No	ClinGen ExAC gnomAD
rs1383144903 CA386273860	2515	P>S		No	ClinGen gnomAD
rs1320648993 CA386273881	2516	V>G		No	ClinGen TOPMed gnomAD
rs140552393 CA242414158	2517	A>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs140552393 CA6743718	2517	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743719 rs749331612	2522	A>T		No	ClinGen ExAC TOPMed gnomAD
CA6743721 rs779157503	2523	S>R		No	ClinGen ExAC gnomAD
rs974163391 CA242414187	2525	L>F		No	ClinGen Ensembl
CA6743722 rs746045243	2527	Q>R		No	ClinGen ExAC gnomAD
rs772469775 CA6743723	2528	K>R		No	ClinGen ExAC gnomAD
COSM1188578 rs767396129 CA6743737	2529	M>I	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs1456847915 CA386274138	2529	M>V		No	ClinGen gnomAD
CA386274147 rs1387211827	2530	K>E		No	ClinGen gnomAD
rs1382891635 CA386274158	2531	S>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA386274161 rs1323013392	2532	I>L		No	ClinGen gnomAD
CA386274170 rs1344748477	2533	S>A		No	ClinGen gnomAD
CA6743740 rs756115922	2535	A>P		No	ClinGen ExAC gnomAD
rs756115922 CA6743739	2535	A>T		No	ClinGen ExAC gnomAD
rs1237862346 CA386274195	2537	C>G		No	ClinGen gnomAD
rs1486543004 CA386274229	2540	L>M		No	ClinGen gnomAD
rs750574576 CA6743741	2542	S>F		No	ClinGen ExAC TOPMed gnomAD
rs758688020 CA6743742	2543	K>E		No	ClinGen ExAC gnomAD
CA6743743 rs780424379	2545	L>W		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	2546	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs528441378 CA6743745	2547	Q>E		No	ClinGen 1000Genomes ExAC gnomAD
rs781693478 CA6743746	2547	Q>P		No	ClinGen ExAC
rs1269828186 CA386274331	2550	G>R		No	ClinGen TOPMed gnomAD
CA6743769 rs751859465	2553	V>F		No	ClinGen ExAC
rs111400774 CA242416742	2554	V>F		No	ClinGen gnomAD
rs755302660 CA6743770	2555	K>N		No	ClinGen ExAC gnomAD
CA386274748 rs1456034352	2556	N>D		No	ClinGen TOPMed
rs778766401 CA242416765	2557	L>S		No	ClinGen Ensembl
CA6743771 rs781400772	2557	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1198811953 CA386274773	2558	L>S		No	ClinGen TOPMed
CA6743773 rs770137347	2560	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1461440872 CA386274808	2562	K>E		No	ClinGen gnomAD
rs1336290751 CA386274832	2564	L>S		No	ClinGen gnomAD
CA386274853 rs1306246960	2566	L>S		No	ClinGen TOPMed
rs372360583 CA6743776	2568	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs577332098 CA6743777	2571	C>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386274884 rs1247582657	2571	C>R		No	ClinGen TOPMed gnomAD
rs759163867 CA6743778	2571	C>W		No	ClinGen ExAC gnomAD
rs577332098 CA386274886	2571	C>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386274909 rs1292353017	2574	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1222919546 CA386274918	2575	Q>R		No	ClinGen TOPMed gnomAD
TCGA novel	2576	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743779 rs771813928	2577	K>E		No	ClinGen ExAC TOPMed gnomAD
CA386274940 rs1565810699	2578	I>K		No	ClinGen Ensembl
CA386274950 rs1481198784	2579	K>N		No	ClinGen gnomAD
CA386274973 rs1203248857 COSM933955	2583	E>K	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs760523340 CA6743781	2586	E>G		No	ClinGen ExAC gnomAD
COSM430162 rs200357157 CA6743780	2586	E>K	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD
rs763876486 CA6743782	2587	A>V		No	ClinGen ExAC gnomAD
rs763083231 CA6743784	2593	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs751749567 CA386275051	2594	C>S		No	ClinGen ExAC gnomAD
CA6743786 rs751749567	2594	C>Y		No	ClinGen ExAC gnomAD
CA386275069 rs1437283349	2597	E>K		No	ClinGen TOPMed
rs969272691 CA242416924	2598	K>N		No	ClinGen Ensembl
rs201781455 CA6743787	2599	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1178702326 CA386275095	2600	E>D		No	ClinGen TOPMed
rs773719988 CA242416937	2601	S>P		No	ClinGen gnomAD
CA242416940 CA6743790 rs369203212	2602	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs375163803 CA6743791	2603	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	2604	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA386275127 rs1209923636	2605	E>D		No	ClinGen TOPMed
TCGA novel	2607	E>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1593458399 CA386275156	2609	V>G		No	ClinGen Ensembl
CA386275154 rs1283119641	2609	V>L		No	ClinGen TOPMed
CA6743793 rs1061436	2612	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1061436 CA6743792 VAR_022163	2612	E>Q		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1310150445 CA386275185	2613	L>P		No	ClinGen TOPMed
TCGA novel	2614	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743795 rs148427016	2614	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386275200 rs1593458426	2616	P>A		No	ClinGen Ensembl
rs141701848 CA6743796	2616	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743798 rs746728087	2617	A>S		No	ClinGen ExAC gnomAD
CA242417017 rs746728087	2617	A>T		No	ClinGen ExAC gnomAD
CA6743799 rs768524022	2618	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1241590244 CA386275216	2619	L>P		No	ClinGen gnomAD
CA386275219 rs1379613522	2620	L>V		No	ClinGen TOPMed
CA386275226 rs1348034116	2621	W>*		No	ClinGen Ensembl
CA6743804 rs759679612	2625	K>Q		No	ClinGen ExAC gnomAD
rs1006467136 CA242417067	2625	K>R		No	ClinGen TOPMed gnomAD
CA6743805 rs767586083	2626	L>P		No	ClinGen ExAC TOPMed gnomAD
rs1253674503 CA386275261	2626	L>V		No	ClinGen TOPMed
CA6743808 rs764421472	2628	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA6743806 COSM278063 rs752995039	2628	R>W	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs559137147 CA242417089	2629	I>T		No	ClinGen gnomAD
CA6743810 rs757755764	2630	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1341625463 CA386275284	2631	K>Q		No	ClinGen gnomAD
rs759674615 CA6743811	2632	L>P		No	ClinGen ExAC gnomAD
CA242417134 rs1026146122	2636	Y>C		No	ClinGen TOPMed gnomAD
rs1565810788 CA386275327	2637	S>L		No	ClinGen Ensembl
CA6743814 rs779529045	2638	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs768240288 CA6743816	2640	N>H		No	ClinGen ExAC TOPMed gnomAD
rs776566190 CA6743817	2641	P>T		No	ClinGen ExAC gnomAD
rs1488539667 CA386275356	2642	L>S		No	ClinGen gnomAD
rs762178863 CA6743828	2646	C>G		No	ClinGen ExAC gnomAD
rs1317079186 CA386275403	2647	I>V		No	ClinGen TOPMed
rs765683951 CA386275415	2648	F>L		No	ClinGen ExAC TOPMed gnomAD
rs910454283 CA242417355	2652	G>S		No	ClinGen gnomAD
rs779591681 COSM199570 CA6743832	2653	A>T	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs914254454 CA242417382	2654	V>A		No	ClinGen TOPMed
COSM1270129 rs147838898 CA6743834	2654	V>I	oesophagus [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs781008844 CA6743835	2655	A>V		No	ClinGen ExAC gnomAD
rs747907268 CA6743836	2656	M>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	2659	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200707485 CA6743838	2660	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA242417412 rs1037554700	2660	I>V		No	ClinGen Ensembl
CA386275496 rs1444625915	2661	D>E		No	ClinGen gnomAD
CA386275506 rs1170048931	2663	V>I		No	ClinGen TOPMed
CA386275508 rs1170048931	2663	V>L		No	ClinGen TOPMed
rs770832540 CA6743840	2665	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	2667	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs901629445 CA242417442	2667	L>P		No	ClinGen TOPMed
TCGA novel	2668	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6743844 rs776859795	2669	M>K		No	ClinGen ExAC TOPMed gnomAD
CA6743843 rs139767850	2669	M>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1328636180 CA386275561	2671	I>T		No	ClinGen gnomAD
CA6743845 rs577369061	2671	I>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1200114435 CA386275564	2672	A>T		No	ClinGen TOPMed gnomAD
rs1443659312 CA386275570	2673	P>S		No	ClinGen gnomAD
rs1181157603 CA386275581	2674	L>F		No	ClinGen gnomAD
CA6743847 rs750799541	2676	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs765551216 CA6743846	2676	R>W		No	ClinGen ExAC gnomAD
rs763500617 CA6743848	2678	L>F		No	ClinGen ExAC gnomAD
CA386275605 rs1394760783	2678	L>P		No	ClinGen gnomAD
rs374273784 CA242417496	2680	S>N		No	ClinGen Ensembl
CA386275622 rs1593458700	2681	T>P		No	ClinGen Ensembl
rs1405561915 CA386275631	2682	Y>C		No	ClinGen gnomAD
rs1332501213 CA386275629	2682	Y>H		No	ClinGen gnomAD
rs1341213386 CA386275658	2686	D>N		No	ClinGen gnomAD
rs1220579474 CA386276186	2690	K>*		No	ClinGen gnomAD
CA6743867 rs766861815	2690	K>M		No	ClinGen ExAC TOPMed gnomAD
CA386276188 rs766861815	2690	K>R		No	ClinGen ExAC TOPMed gnomAD
CA6743868 rs774752571	2691	N>S		No	ClinGen ExAC gnomAD
rs760164413 CA6743869	2693	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs149907561 CA6743870	2695	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386276216 rs1256166008	2695	E>K		No	ClinGen gnomAD
CA6743872 rs755827583	2697	I>M		No	ClinGen ExAC gnomAD
rs149982185 CA6743871	2697	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA386276268 rs1482509013	2702	K>R		No	ClinGen gnomAD
CA6743876 rs778866140	2703	L>P		No	ClinGen ExAC gnomAD
rs1156828621 CA386276276	2704	V>I		No	ClinGen gnomAD
rs1387236946 CA386276323	2710	S>L		No	ClinGen gnomAD
rs1344606653 CA386276355	2714	A>T		No	ClinGen gnomAD
TCGA novel	2714	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1402834846 CA386276411	2717	Q>H		No	ClinGen gnomAD
rs1269279507 CA386276459	2720	A>V		No	ClinGen TOPMed
rs374626049 CA6743879	2722	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs374626049 CA6743880	2722	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743881 rs770002866	2725	A>T		No	ClinGen ExAC TOPMed gnomAD
CA6743883 rs182798292	2727	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6743884 rs771169465	2727	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA6743882 rs182798292	2727	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA386276567 rs1291741135	2728	K>Q		No	ClinGen gnomAD
rs774908710 CA6743885	2729	K>N		No	ClinGen ExAC gnomAD
TCGA novel	2729	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768208738 CA6743887	2732	A>V		No	ClinGen ExAC gnomAD
CA386276673 rs1180008829	2733	L>V		No	ClinGen gnomAD
rs1037027870 CA242419076	2734	E>Q		No	ClinGen TOPMed gnomAD
CA242419223 rs975315153	2736	V>A		No	ClinGen TOPMed
CA386276788 rs1240222580	2737	T>I		No	ClinGen gnomAD
rs776670472 CA242419227	2738	N>T		No	ClinGen Ensembl
rs1236812381 CA386276824	2739	P>L		No	ClinGen TOPMed
CA6743894 rs550346514	2739	P>T		No	ClinGen 1000Genomes ExAC gnomAD
CA6743895 rs750276172	2740	D>Y		No	ClinGen ExAC TOPMed
CA386276897 rs1422369447	2744	K>M		No	ClinGen gnomAD
rs779969473 CA6743897	2744	K>Q		No	ClinGen ExAC TOPMed gnomAD
rs1166902251	2747	M>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA386276932 rs1461328972	2747	M>V		No	ClinGen gnomAD
CA386276962 rs1329084693	2749	K>T		No	ClinGen gnomAD
CA6743899 rs756180074	2750	H>Y		No	ClinGen ExAC gnomAD
rs1447073665 CA386276983	2751	K>Q		No	ClinGen gnomAD
CA386277038 rs1335405859	2756	A>P		No	ClinGen gnomAD
CA6743900 rs777948688	2757	K>R		No	ClinGen ExAC TOPMed gnomAD
CA6743901 rs749453497	2758	K>R		No	ClinGen ExAC TOPMed gnomAD
rs749453497 CA242419247	2758	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1231816913 CA386277057	2759	R>K		No	ClinGen TOPMed
rs143303905 CA6743907	2762	E>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs1324701915 CA386277085	2763	F>L		No	ClinGen TOPMed
CA6743908 rs118052100	2765	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6743909 rs746241915	2766	P>A		No	ClinGen ExAC TOPMed gnomAD
CA386277110 rs1391070238	2767	G>E		No	ClinGen TOPMed
CA6743910 rs370882773	2769	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA6743911 rs776160013	2769	K>T		No	ClinGen ExAC gnomAD
CA242419293 rs535706848	2770	A>T		No	ClinGen 1000Genomes gnomAD
rs1175335991 CA386277139	2771	K>N		No	ClinGen TOPMed gnomAD
rs79372140 CA242419307	2773	Q>K		No	ClinGen Ensembl
rs1449533387 CA386277150	2773	Q>R		No	ClinGen gnomAD
rs1302944672 CA386277190	2778	L>R		No	ClinGen gnomAD
rs1280490446 CA386277198	2779	K>N		No	ClinGen gnomAD
CA386277191 rs1398704705	2779	K>Q		No	ClinGen gnomAD
rs1473726669 CA386277203	2780	D>G		No	ClinGen TOPMed
CA386277216 rs1223114627	2782	A>P		No	ClinGen gnomAD
CA386277218 rs1261541847	2782	A>V		No	ClinGen gnomAD
rs768015734 CA6743913	2783	M>V		No	ClinGen ExAC gnomAD
rs1402018618 CA386277232	2784	V>G		No	ClinGen gnomAD
CA386277228 rs1370908623	2784	V>M		No	ClinGen TOPMed
CA6743914 rs140645724	2785	E>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD

No associated diseases with O75691

2 regional properties for O75691

Type	Name	Position	InterPro Accession
domain	U3 small nucleolar RNA-associated protein 20, N-terminal	910 - 1533	IPR011430
domain	U3 small nucleolar RNA-associated protein 20, C-terminal	1813 - 2030	IPR046523

Functions

		Description
EC Number
Subcellular Localization	Nucleus, nucleolus	Colocalizes with NCL in the nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

7 GO annotations of cellular component

Name	Definition
90S preribosome	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
preribosome, small subunit precursor	A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
small-subunit processome	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

1 GO annotations of molecular function

Name	Definition
RNA binding	Binding to an RNA molecule or a portion thereof.

5 GO annotations of biological process

Name	Definition
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
negative regulation of cell population proliferation	Any process that stops, prevents or reduces the rate or extent of cell proliferation.
rRNA processing	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

1 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P35194	UTP20	U3 small nucleolar RNA-associated protein 20	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR

10	20	30	40	50	60
MKTKPVSHKT	ENTYRFLTFA	ERLGNVNIDI	IHRIDRTASY	EEEVETYFFE	GLLKWRELNL
70	80	90	100	110	120
TEHFGKFYKE	VIDKCQSFNQ	LVYHQNEIVQ	SLKTHLQVKN	SFAYQPLLDL	VVQLARDLQM
130	140	150	160	170	180
DFYPHFPEFF	LTITSILETQ	DTELLEWAFT	SLSYLYKYLW	RLMVKDMSSI	YSMYSTLLAH
190	200	210	220	230	240
KKLHIRNFAA	ESFTFLMRKV	SDKNALFNLM	FLDLDKHPEK	VEGVGQLLFE	MCKGVRNMFH
250	260	270	280	290	300
SCTGQAVKLI	LRKLGPVTET	ETQLPWMLIG	ETLKNMVKST	VSYISKEHFG	TFFECLQESL
310	320	330	340	350	360
LDLHTKVTKT	NCCESSEQIK	RLLETYLILV	KHGSGTKIPT	PADVCKVLSQ	TLQVASLSTS
370	380	390	400	410	420
CWETLLDVIS	ALILGENVSL	PETLIKETIE	KIFESRFEKR	LIFSFSEVMF	AMKQFEQLFL
430	440	450	460	470	480
PSFLSYIVNC	FLIDDAVVKD	EALAILAKLI	LNKAAPPTAG	SMAIEKYPLV	FSPQMVGFYI
490	500	510	520	530	540
KQKKTRSKGR	NEQFPVLDHL	LSIIKLPPNK	DTTYLSQSWA	ALVVLPHIRP	LEKEKVIPLV
550	560	570	580	590	600
TGFIEALFMT	VDKGSFGKGN	LFVLCQAVNT	LLSLEESSEL	LHLVPVERVK	NLVLTFPLEP
610	620	630	640	650	660
SVLLLTDLYY	QRLALCGCKG	PLSQEALMEL	FPKLQANIST	GVSKIRLLTI	RILNHFDVQL
670	680	690	700	710	720
PESMEDDGLS	ERQSVFAILR	QAELVPATVN	DYREKLLHLR	KLRHDVVQTA	VPDGPLQEVP
730	740	750	760	770	780
LRYLLGMLYI	NFSALWDPVI	ELISSHAHEM	ENKQFWKVYY	EHLEKAATHA	EKELQNDMTD
790	800	810	820	830	840
EKSVGDESWE	QTQEGDVGAL	YHEQLALKTD	CQERLDHTNF	RFLLWRALTK	FPERVEPRSR
850	860	870	880	890	900
ELSPLFLRFI	NNEYYPADLQ	VAPTQDLRRK	GKGMVAEEIE	EEPAAGDDEE	LEEEAVPQDE
910	920	930	940	950	960
SSQKKKTRRA	AAKQLIAHLQ	VFSKFSNPRA	LYLESKLYEL	YLQLLLHQDQ	MVQKITLDCI
970	980	990	1000	1010	1020
MTYKHPHVLP	YRENLQRLLE	DRSFKEEIVH	FSISEDNAVV	KTAHRADLFP	ILMRILYGRM
1030	1040	1050	1060	1070	1080
KNKTGSKTQG	KSASGTRMAI	VLRFLAGTQP	EEIQIFLDLL	FEPVRHFKNG	ECHSAVIQAV
1090	1100	1110	1120	1130	1140
EDLDLSKVLP	LGRQHGILNS	LEIVLKNISH	LISAYLPKIL	QILLCMTATV	SHILDQREKI
1150	1160	1170	1180	1190	1200
QLRFINPLKN	LRRLGIKMVT	DIFLDWESYQ	FRTEEIDAVF	HGAVWPQISR	LGSESQYSPT
1210	1220	1230	1240	1250	1260
PLLKLISIWS	RNARYFPLLA	KQKPGHPECD	ILTNVFAILS	AKNLSDATAS	IVMDIVDDLL
1270	1280	1290	1300	1310	1320
NLPDFEPTET	VLNLLVTGCV	YPGIAENIGE	SITIGGRLIL	PHVPAILQYL	SKTTISAEKV
1330	1340	1350	1360	1370	1380
KKKKNRAQVS	KELGILSKIS	KFMKDKEQSS	VLITLLLPFL	HRGNIAEDTE	VDILVTVQNL
1390	1400	1410	1420	1430	1440
LKHCVDPTSF	LKPIAKLFSV	IKNKLSRKLL	CTVFETLSDF	ESGLKYITDV	VKLNAFDQRH
1450	1460	1470	1480	1490	1500
LDDINFDVRF	ETFQTITSYI	KEMQIVDVNY	LIPVMHNCFY	NLELGDMSLS	DNASMCLMSI
1510	1520	1530	1540	1550	1560
IKKLAALNVT	EKDYREIIHR	SLLEKLRKGL	KSQTESIQQD	YTTILSCLIQ	TFPNQLEFKD
1570	1580	1590	1600	1610	1620
LVQLTHYHDP	EMDFFENMKH	IQIHRRARAL	KKLAKQLMEG	KVVLSSKSLQ	NYIMPYAMTP
1630	1640	1650	1660	1670	1680
IFDEKMLKHE	NITTAATEII	GAICKHLSWS	AYMYYLKHFI	HVLQTGQINQ	KLGVSLLVIV
1690	1700	1710	1720	1730	1740
LEAFHFDHKT	LEEQMGKIEN	EENAIEAIEL	PEPEAMELER	VDEEEKEYTC	KSLSDNGQPG
1750	1760	1770	1780	1790	1800
TPDPADSGGT	SAKESECITK	PVSFLPQNKE	EIERTIKNIQ	GTITGDILPR	LHKCLASTTK
1810	1820	1830	1840	1850	1860
REEEHKLVKS	KVVNDEEVVR	VPLAFAMVKL	MQSLPQEVME	ANLPSILLKV	CALLKNRAQE
1870	1880	1890	1900	1910	1920
IRDIARSTLA	KIIEDLGVHF	LLYVLKELQT	TLVRGYQVHV	LTFTVHMLLQ	GLTNKLQVGD
1930	1940	1950	1960	1970	1980
LDSCLDIMIE	IFNHELFGAV	AEEKEVKQIL	SKVMEARRSK	SYDSYEILGK	FVGKDQVTKL
1990	2000	2010	2020	2030	2040
ILPLKEILQN	TTSLKLARKV	HETLRRITVG	LIVNQEMTAE	SILLLSYGLI	SENLPLLTEK
2050	2060	2070	2080	2090	2100
EKNPVAPAPD	PRLPPQSCLL	LPPTPVRGGQ	KAVVSRKTNM	HIFIESGLRL	LHLSLKTSKI
2110	2120	2130	2140	2150	2160
KSSGECVLEM	LDPFVSLLID	CLGSMDVKVI	TGALQCLIWV	LRFPLPSIET	KAEQLTKHLF
2170	2180	2190	2200	2210	2220
LLLKDYAKLG	AARGQNFHLV	VNCFKCVTIL	VKKVKSYQIT	EKQLQVLLAY	AEEDIYDTSR
2230	2240	2250	2260	2270	2280
QATAFGLLKA	ILSRKLLVPE	IDEVMRKVSK	LAVSAQSEPA	RVQCRQVFLK	YILDYPLGDK
2290	2300	2310	2320	2330	2340
LRPNLEFMLA	QLNYEHETGR	ESTLEMIAYL	FDTFPQGLLH	ENCGMFFIPL	CLMTINDDSA
2350	2360	2370	2380	2390	2400
TCKKMASMTI	KSLLGKISLE	KKDWLFDMVT	TWFGAKKRLN	RQLAALICGL	FVESEGVDFE
2410	2420	2430	2440	2450	2460
KRLGTVLPVI	EKEIDPENFK	DIMEETEEKA	ADRLLFSFLT	LITKLIKECN	IIQFTKPAET
2470	2480	2490	2500	2510	2520
LSKIWSHVHS	HLRHPHNWVW	LTAAQIFGLL	FASCQPEELI	QKWNTKKTKK	HLPEPVAIKF
2530	2540	2550	2560	2570	2580
LASDLDQKMK	SISLASCHQL	HSKFLDQSLG	EQVVKNLLFA	AKVLYLLELY	CEDKQSKIKE
2590	2600	2610	2620	2630	2640
DLEEQEALED	GVACADEKAE	SDGEEKEEVK	EELGRPATLL	WLIQKLSRIA	KLEAAYSPRN
2650	2660	2670	2680	2690	2700
PLKRTCIFKF	LGAVAMDLGI	DKVKPYLPMI	IAPLFRELNS	TYSEQDPLLK	NLSQEIIELL
2710	2720	2730	2740	2750	2760
KKLVGLESFS	LAFASVQKQA	NEKRALRKKR	KALEFVTNPD	IAAKKKMKKH	KNKSEAKKRK
2770	2780
IEFLRPGYKA	KRQKSHSLKD	LAMVE