AiPD: Autoinhibited Protein Database

Gene name	ANP32CP (PP32R1)
Protein name	Putative uncharacterized protein ANP32CP
Names	Acidic leucine-rich nuclear phosphoprotein 32 family member C , Phosphoprotein 32-related protein 1 , Tumorigenic protein pp32r1
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
EC number	3.1.4.11: Phosphoric diester hydrolases
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

117-159 (Autoinhibitory domain) SS

117-159 (Autoinhibitory domain)

1-159 (Leucine-rich region)

PTM (Phosphorylation of Ser158 or both Ser158 and Ser204), Others (C-terminal acidic region-mediated neutralization)

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-O43423-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs2288674 VAR_026702	23	A>V	No	UniProt dbSNP
rs2288675 VAR_020419	71	R>K	No	UniProt dbSNP
rs17008716 VAR_048314	105	L>P	No	UniProt dbSNP
rs76372915 VAR_026703	140	Y>H	No	UniProt dbSNP
rs2288676 VAR_020420	204	E>G	No	UniProt dbSNP

Type	Name	Position	InterPro Accession
domain	ABC transporter-like, ATP-binding domain	423 - 646	IPR003439-1
domain	ABC transporter-like, ATP-binding domain	1211 - 1444	IPR003439-2
domain	AAA+ ATPase domain	450 - 639	IPR003593-1
domain	AAA+ ATPase domain	1237 - 1419	IPR003593-2
domain	ABC transporter type 1, transmembrane domain	82 - 350	IPR011527-1
domain	ABC transporter type 1, transmembrane domain	860 - 1158	IPR011527-2
conserved_site	ABC transporter-like, conserved site	548 - 562	IPR017871
domain	CFTR regulator domain	639 - 849	IPR025837
domain	Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette domain 1	389 - 670	IPR047082

		Description
EC Number	3.1.4.11	Phosphoric diester hydrolases
Subcellular Localization	Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
perinuclear region of cytoplasm	Cytoplasm situated near, or occurring around, the nucleus.

Name	Definition
histone binding	Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.

Name	Definition
nucleocytoplasmic transport	The directed movement of molecules between the nucleus and the cytoplasm.
regulation of apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P51122	ANP32A	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Bos taurus (Bovine)	SS
Q8HY67	ANP32A	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Canis lupus familiaris (Dog) (Canis familiaris)	SS
Q9V895	Anp32a	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Drosophila melanogaster (Fruit fly)	SS
Q9BTT0	ANP32E	Acidic leucine-rich nuclear phosphoprotein 32 family member E	Homo sapiens (Human)	SS
Q92688	ANP32B	Acidic leucine-rich nuclear phosphoprotein 32 family member B	Homo sapiens (Human)	SS
P39687	ANP32A	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Homo sapiens (Human)	EV
O35381	Anp32a	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Mus musculus (Mouse)	SS
P49911	Anp32a	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Rattus norvegicus (Rat)	SS
Q7Y180	Os03g0668900	Acidic leucine-rich nuclear phosphoprotein 32-related protein 2	Oryza sativa subsp. japonica (Rice)	SS
Q9SCQ7	At3g50690	Acidic leucine-rich nuclear phosphoprotein 32-related protein	Arabidopsis thaliana (Mouse-ear cress)	SS
Q7ZUP0	anp32a	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Danio rerio (Zebrafish) (Brachydanio rerio)	SS