O35698

PR
Gene name
Rbmy1a1 (Rbm)
Protein name
RNA-binding motif protein, Y chromosome, family 1 member A1
Names
RNA-binding motif protein 1, Y chromosome RNA recognition motif 1
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:19657
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

53-172 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O35698

Entry ID Method Resolution Chain Position Source
AF-O35698-F1 Predicted AlphaFoldDB

1 variants for O35698

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3412869453 235 H>R No EVA

No associated diseases with O35698

1 regional properties for O35698

Type Name Position InterPro Accession
domain RNA recognition motif domain 8 - 86 IPR000504

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
male germ cell nucleus The nucleus of a male germ cell, a reproductive cell in males.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

5 GO annotations of biological process

Name Definition
hematopoietic progenitor cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
male gonad development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
positive regulation of mRNA splicing, via spliceosome Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O35698 Rbmy1a1 RNA-binding motif protein, Y chromosome, family 1 member A1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAETNQPGKI FIGGLNIKTR QKTLQEIFGR FGPVARVILM RDRETKKSRG FAFLTFRRLA
70 80 90 100 110 120
DAKNAVKEMN GVILDGKRIK VKQARRPSSL ESGSKKRPPS FSRTRGASRI LKCGRGGRSR
130 140 150 160 170 180
ARSGPSCEGN LGGDRYTPNF NVSSSGRHFA VKRNPSSKRD DPPSKRSATS AQTRSNTGLR
190 200 210 220 230 240
GREPHRREIS RNMPRGEPAS SRRDEYPLPR DYGQSSNDRK YESTSRGYCD YGNYHSREES
250 260 270 280 290 300
ASKVFSDHAG YLGGRDRDFS EYLSGNSYRD TYRSYGRFHE APSARGGNNR YDDYSNSQDG
310 320 330 340 350 360
YGGRGEPYIS NRSNIYSSDY ERSGRQEVLP PPIDREYFDR EGRQERGHSP KDGLYSASRE
370
SYSSNTKIWG IPWRSWRKQI