O02639

PR
Gene name
rpl-19 (C09D4.5)
Protein name
60S ribosomal protein L19
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_C09D4.5
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O02639

Entry ID Method Resolution Chain Position Source
AF-O02639-F1 Predicted AlphaFoldDB

No variants for O02639

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O02639

No associated diseases with O02639

3 regional properties for O02639

Type Name Position InterPro Accession
domain Ribosomal protein L19/L19e 3 - 149 IPR000196
conserved_site Ribosomal protein L19/L19e conserved site 7 - 26 IPR023638
domain Ribosomal protein L19, eukaryotic 4 - 167 IPR033935

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
determination of adult lifespan The pathways that regulate the duration of the adult phase of the life-cycle of an animal.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LUQ6 RPL19B 60S ribosomal protein L19-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSNLRLQKRL ASAVLKCGKH RVWLDPNEVS EISGANSRQS IRRLVNDGLI IRKPVTVHSR
70 80 90 100 110 120
FRAREYEEAR RKGRHTGYGK RRGTANARMP EKTLWIRRMR VLRNLLRRYR DAKKLDKHLY
130 140 150 160 170 180
HELYLRAKGN NFKNKKNLIE YIFKKKTENK RAKQLADQAQ ARRDKNKESR KRREERQVVK
190
RAELLRKISQ SEKVIAGK