F1MLB4

PR
Gene name
DNAAF3
Protein name
Dynein axonemal assembly factor 3
Names
Species
Bos taurus (Bovine)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-66 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for F1MLB4

Entry ID Method Resolution Chain Position Source
AF-F1MLB4-F1 Predicted AlphaFoldDB

No variants for F1MLB4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for F1MLB4

No associated diseases with F1MLB4

2 regional properties for F1MLB4

Type Name Position InterPro Accession
domain Domain of unknown function DUF4470 16 - 122 IPR027974
domain Dynein assembly factor 3, C-terminal domain 155 - 439 IPR028235

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Dynein axonemal particle
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
dynein axonemal particle An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
D3ZCM9 Dnaaf3 Dynein axonemal assembly factor 3 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MTTPAGSGTG FGSVSWWGLS PAVDLQAESP PVDPDSQAET EHETPELNVL LLGSVDGRHL
70 80 90 100 110 120
LRTLARAALW PRRRFHFYVL ENNLEAVARH ILIFSLALED PEKMGLQERS ETFLEVWGNA
130 140 150 160 170 180
LLRPPVAAFV RAQAGRLAHL VPEPDRLAEQ LPWLSLGALK FRERDALEAV FRFWAGGEKG
190 200 210 220 230 240
PEAFPMSRLW DSRLRQYLGS RYDARHGVSD WDLHMKLHDR GARVIHTREF RRWRDTGVAF
250 260 270 280 290 300
ELRDSSAYHV PNRTLASGRL LSHRGERVAA RGYWGDIATG PFVAFGIEAD DETLLRTSNG
310 320 330 340 350 360
QPVKTACEIT EHNVAELFRE MAAWGHPRAA EGDPEQVQGG AEGSSEPAAP APEPFTVHFL
370 380 390 400 410 420
SLDSAHTLHH KSCYMGQFQL LYVACGMVHL LSAELGACVA PGGRLIVELA QFLVDLRQEQ
430 440 450 460 470 480
LQAFSSRVGE LAQAAGFAPQ LGGKPSDTFA RFYKAGDSAP GHEDPAVESG TPPPEVLAPP
490 500 510 520 530 540
LEATDPPSED RTQPLESGNP PSEPLKLTSE SQASLLEASV PPTGSQAPKS ENQTVPPETK
YPIP