D3ZCM9
Gene name |
Dnaaf3 |
Protein name |
Dynein axonemal assembly factor 3 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:100359753 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for D3ZCM9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-D3ZCM9-F1 | Predicted | AlphaFoldDB |
No variants for D3ZCM9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for D3ZCM9 | |||||
No associated diseases with D3ZCM9
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| dynein axonemal particle | An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| axonemal dynein complex assembly | The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. |
| determination of left/right symmetry | The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. |
| heart development | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| motile cilium assembly | The aggregation, arrangement and bonding together of a set of components to form a motile cilium. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F1MLB4 | DNAAF3 | Dynein axonemal assembly factor 3 | Bos taurus (Bovine) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTPAGSGNG | FGTVSWWGLS | PALDLQAESP | PVDPDSQSKT | EHKIPELDAL | LLGSVDGRHM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRTLARAMLW | PLRRFNFYVL | ENNLEAVARH | MLIFSLALEE | PEKMGLQERS | ETFLELWGNA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLRPSVAAFL | RAQASHLSNL | VPEPDRLEEL | LPWLSLRPLK | FRERDALEAV | FRFWSGGEKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PEVFPMSRLW | DSRLRHYLGS | RYDARRGVAD | WDLRMKLHDR | GAQVIHFHEF | RRWRDTGVAF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELRDLSAYHV | PNRTMASGRL | LSHRGERVAA | RGYWGDIATG | PFVAFGIEAD | DKSLLRTSNG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QPVKTASEIT | QHNVTELFRD | VAAWRGPRAI | KGNVEETKSP | EPDAPAQEPF | TIHFLPLDSS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QTLHHKTCYR | GRFQLLYVSC | GMIHLLSPEL | GACVAPGGNL | VVELARYLVD | LRPKELKAFS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DRVVEIAQAA | GFAPHTGTKP | SETFARFYKL | GDSTRGGGDS | AVESGPVPSK | VLAPTPESIN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PPQADQAPSL | EVMSPPKVDQ | TPPLEAMSPP | EADQAPPLEA | MSPPRADQIP | PLEAMSPLQA |
| 550 | 560 | 570 | 580 | ||
| EVVLPLEAIS | PPQADLAPPP | EVISPVQEAL | AMSSAIAPLK | HVT |