D3ZN43

PR
Gene name
Ndufaf6
Protein name
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:297821
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D3ZN43

Entry ID Method Resolution Chain Position Source
AF-D3ZN43-F1 Predicted AlphaFoldDB

1 variants for D3ZN43

Variant ID(s) Position Change Description Diseaes Association Provenance
rs106931344 131 H>Y No EVA

No associated diseases with D3ZN43

No regional properties for D3ZN43

Type Name Position InterPro Accession
No domain, repeats, and functional sites for D3ZN43

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane
  • Peripherally localized on the matrix face of the mitochondrial inner membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
mitochondrial respiratory chain complex I assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A2AIL4 Ndufaf6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 Mus musculus (Mouse) PR
10 20 30 40 50 60
MATSMLGSVP GPRPFGLAGL FRRRPPRDPW ERVRRLPRLS AVRRSVAAAS GPGIPDSHLY
70 80 90 100 110 120
CLELLRKRDY ESYLCSLLFP AECQRSASAL RAFNVELAQV KDSVSEKTIG LMRMQFWRKA
130 140 150 160 170 180
VEDMFCDNPP HQPVAMELWK AVKRHNLTKR WLLRIIDERE KNLDDKAYRS IRELETYAEN
190 200 210 220 230 240
TQSSLLYLTL EVLGVKDVHA DHAASHIGKA QGIVTCLRAT PYHSSRRQVF LPMDVCVQHG
250 260 270 280 290 300
VSQEDFLRRN QDKNVRDVVY DIASQAHLHL KHARSFHSRV PAEAFPAFLQ TVSLEDYLKK
310 320 330
IQRVDFDIFH PSLQQKNTLL PLSLYIQSWR KRY