Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A6QNR1

Entry ID Method Resolution Chain Position Source
AF-A6QNR1-F1 Predicted AlphaFoldDB

62 variants for A6QNR1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs525707683 2 R>P No EVA
rs458272211 3 R>G No EVA
rs450280440 4 A>E No EVA
rs450280440 4 A>G No EVA
rs463906678 5 S>N No EVA
rs480392171 6 S>P No EVA
rs445372604 10 A>G No EVA
rs434867645 10 A>P No EVA
rs464299204 11 V>G No EVA
rs432978932 12 A>S No EVA
rs476509931 13 G>A No EVA
rs435139739 14 S>A No EVA
rs455238468 14 S>Y No EVA
rs472278665 17 E>A No EVA
rs457878146 19 Q>H No EVA
rs440873227 19 Q>P No EVA
rs443817435 20 D>G No EVA
rs471773616 20 D>Y No EVA
rs463842980 21 G>S No EVA
rs449604387 23 E>G No EVA
rs459683254 25 D>A No EVA
rs479881030 26 G>W No EVA
rs445273605 27 S>G No EVA
rs465498511 27 S>R No EVA
rs449916373 30 N>H No EVA
rs470018799 31 D>Y No EVA
rs443893314 54 Q>E No EVA
rs474919261 136 K>* No EVA
rs483186370 150 E>D No EVA
rs448584679 155 L>I No EVA
rs479341655 157 H>Q No EVA
rs522163790 161 R>L No EVA
rs474871762 171 E>D No EVA
rs454058423 180 L>P No EVA
rs470546623 181 A>D No EVA
rs439245304 182 L>P No EVA
rs462597046 183 K>N No EVA
rs441744521 185 E>G No EVA
rs476311410 185 E>Q No EVA
rs477961277 188 A>D No EVA
rs477961277 188 A>G No EVA
rs458300436 188 A>T No EVA
rs470052342 189 Q>E No EVA
rs470052342 189 Q>K No EVA
rs435678892 189 Q>P No EVA
rs468327983 190 A>P No EVA
rs433784167 191 Q>E No EVA
rs470883734 191 Q>H No EVA
rs433784167 191 Q>K No EVA
rs453995578 191 Q>P No EVA
rs453995578 191 Q>R No EVA
rs432700985 192 Q>E No EVA
rs456118550 192 Q>P No EVA
rs476291994 193 G>A No EVA
rs447229174 194 H>P No EVA
rs472751211 197 Y>F No EVA
rs797944393 199 L>P No EVA
rs443135007 204 Q>R No EVA
rs459741673 205 R>C No EVA
rs479835023 207 L>V No EVA
rs438891541 208 V>G No EVA
rs715475123 230 R>K No EVA

No associated diseases with A6QNR1

No regional properties for A6QNR1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A6QNR1

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cleavage involved in rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96EU6 RRP36 Ribosomal RNA processing protein 36 homolog Homo sapiens (Human) PR
Q3UFY0 Rrp36 Ribosomal RNA processing protein 36 homolog Mus musculus (Mouse) PR
10 20 30 40 50 60
MRRASSCGGA VAGSPSEAQD GGEDDGSLRN DTSHMSFEEL LELQSQVGTK AYKQLVTGSS
70 80 90 100 110 120
TKKQSSRPPV QKGCVADKHR PLEMSAKVRV PFLRQVVPIS KKVARDPRFD DLSGEYNPEV
130 140 150 160 170 180
FDKTYQFLDD IRAREKELVK KQLKKHRSGE EHEKLQHLLQ RMEQQEMAQK ERKRQQELRL
190 200 210 220 230 240
ALKQERRAQA QQGHRPYFLK KSEQRQLVLA EKFKELKRSK KLESFLSRKR RRNAGKDRRH
LPLSKE